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Displaying results 961 - 970 of 10000 in total
  1. Drug

    Isoleucine

    go.drugbank.com/drugs/DB00167
    ApprovedInvestigationalNutraceutical

    An essential branched-chain aliphatic amino acid found in many proteins. It is an isomer of leucine. It is important in hemoglobin synthesis and regulation of blood sugar and energy levels.

    Mixtures: Aminosyn II in Dextrose, Aminosyn II in Dextrose
  2. Drug

    Valproic acid

    go.drugbank.com/drugs/DB00313
    ApprovedInvestigational

    It is currently a compound of interest in the field of oncology for its anti-proliferative effects and is the subject of many clinical trials in a variety of cancer types. … Valproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in 1881 by Beverly S. Burton.

    Synonyms: 2-n-propyl-n-valeric acid, n-DPAMixtures: Depakine Chronosphere 50 mg Retardgranulat in Beuteln, Depakine Chronosphere 50 mg Retardgranulat in Beuteln
  3. Target

    Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

    go.drugbank.com/bio_entities/BE0005530
    TargetHumans

    Involved in the regulation of synaptic function in excitatory hippocampal synapses. … May be a negative regulator of insulin signaling and glucose metabolism in adipose tissue.

    Synonyms: Mutated in multiple advanced cancers 1
  4. Target

    tRNA-dihydrouridine(20) synthase [NAD(P)+]-like

    go.drugbank.com/bio_entities/BE0020091
    EnzymeHumans

    Specifically modifies U20 in cytoplasmic tRNAs (PubMed:38680565). Activity depends on the presence of guanosine at position 19 in the tRNA substrate (PubMed:38680565). … Catalyzes the NADPH-dependent synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (PubMed:15994936, PubMed:26429968, PubMed:30149704, PubMed:34798057, PubMed:38680565).

    Synonyms: Up-regulated in lung cancer protein 8
  5. Drug

    Glycine

    go.drugbank.com/drugs/DB00145
    ApprovedInvestigationalNutraceuticalVet approved

    It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.

    Mixtures: Aminosyn II in Dextrose, Aminosyn II in Dextrose
  6. Indication

    Bone Diseases, Infectious

    go.drugbank.com/conditions/DBCOND0076351
    Drugs: Cephalexin · Tobramycin
    Synonyms: Infection in Bone
  7. Indication

    Diabetes Mellitus

    go.drugbank.com/conditions/DBCOND0027886
    Drugs: Ammonium chloride · Borneol · Insulin aspart · Insulin degludec · Insulin glargine · Insulin glulisine +4 more
    Synonyms: Ketoacidosis in diabetes mellitus
  8. Indication

    Insomnia

    go.drugbank.com/conditions/DBCOND0017531
    Drugs: Amitriptyline · Brotizolam · Butabarbital · Cinolazepam · Clotiazepam · Daridorexant +31 more
    Synonyms: Difficulty in sleep initiation
  9. Drug

    Lysine

    go.drugbank.com/drugs/DB00123
    ApprovedInvestigationalNutraceutical

    Lysine is a base, as are arginine and histidine. The ε-amino group acts as a site for hydrogen binding and a general base in catalysis. … O-Glycosylation of lysine residues in the endoplasmic reticulum or Golgi apparatus is used to mark certain proteins for secretion from the cell.

    Mixtures: Aminosyn II in Dextrose, Aminosyn II in Dextrose
  10. Drug

    Cefixime

    go.drugbank.com/drugs/DB00671
    ApprovedInvestigational

    [A262995] Third-generation cephalosporins are often a first-line therapy against certain bacterial infections. … [A263031] Cefixime was first approved in the United States in 1986.[L49293]

    Products: CEFIXIMA INN-FARM