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Displaying results 971 - 980 of 10000 in total
  1. Pathway

    Intracellular Signalling Through Histamine H2 Receptor and Histamine

    smpdb.ca/view/SMP0000335
    Signaling

    Histamine can mediate various actions by interacting with histamine receptors (H1, H2, H3 and H4). … Histamine is an organic nitrogenous compound that is involved in local immune responses and it is a neurotransmitter for brain.

    Drugs: ATP · Magnesium cation · Cyclic adenosine monophosphate · Pyrophosphoric acid
  2. Pathway

    Metabolism and Physiological Effects of Indoxyl glucoside (indican)

    smpdb.ca/view/SMP0124742
    Metabolic

    It is a uremic toxin as identified by the European Uremic Toxin Working Group and accumulates in the presence of Lactobacillus bacteria in the gut. … in tryptophan metabolism, leading to an increase in indican synthesis.

    Drugs: Tryptophan · Mesoheme · Indole · Indoxyl sulfate
  3. Pathway

    Metabolism and Phsyiological Effects of Asymmetric dimethylarginine (ADMA)

    smpdb.ca/view/SMP0124747
    Metabolic

    L-arginine is obtained from protein-rich foods like red meat, poultry, dairy and eggs. It is absorbed in the intestine to the blood. … It enters cells in the body and is metabolized to ADMA via the enzyme protein arginine methyltransferase-1. ADMA inhibits nitric oxide synthase, preventing the formation of nitric oxide.

    Drugs: Ademetionine · Arginine
  4. Pathway

    Metabolism and Physiological Effects of Symmetric dimethylarginine (SDMA)

    smpdb.ca/view/SMP0124764
    Metabolic

    L-arginine is obtained from protein-rich foods like red meat, poultry, dairy and eggs. It is absorbed in the intestine to the blood. … It enters cells in the body and is metabolized to SDMA via the enzyme protein arginine methyltransferase-5 or protein arginine methyltransferase-7.

    Drugs: Ademetionine · Arginine · Symmetric dimethylarginine
  5. Pathway

    Metabolism and Physiological Effects of β-Hydroxybutyric acid

    smpdb.ca/view/SMP0126987
    Metabolic

    In the liver mitochondrial matrix, the enzyme can also catalyze the reverse reaction, a step in ketogenesis. Hepatocytes are the main cell type in the liver (~80%). … Glucose is metabolized into pyruvate through glycolysis in the cytoplasm, and pyruvate is completely oxidized to generate ATP through the TCA cycle and oxidative phosphorylation in the mitochondria.

    Drugs: NADH · Acetoacetic acid
  6. Pathway

    Intracellular Signalling Through Adenosine Receptor A2b and Adenosine

    smpdb.ca/view/SMP0000321
    Signaling

    Adenosine is thought to play a role in the pathophysiology of asthma. Stimulation of A2B can induce production of interleukin-8 mast cells.

    Drugs: ATP · Adenosine · Magnesium cation · Zinc · Cyclic adenosine monophosphate · Pyrophosphoric acid
  7. Pathway

    Metabolism and Physiological Effects of 2-Aminobenzoic acid

    smpdb.ca/view/SMP0126869
    Disease

    It can also cause changes in mental status, such as confusion, reduced awareness, agitation, psychosis, seizures, and coma. … In addition, 2-aminobenzoic acid and L-alanine can be biosynthesized from L-kynurenine through its interaction with the enzyme kynureninase.

    Drugs: Tryptophan · Alanine · Formic acid · Kynurenine · Mesoheme · Anthranilic acid +1 more
    Enzymes: Neutral and basic amino acid transport protein rBAT
  8. Pathway

    Metabolism and Physiological Effects of 4-Hydroxyphenylacetic acid

    smpdb.ca/view/SMP0126879
    Metabolic

    p-Hydroxyphenylacetic acid can be found in numerous foods such as olives, cocoa beans, oats, and mushrooms. p-Hydroxyphenylacetic acid can be found throughout all human tissues and in all biofluids. … , and C. propionicum. l-tyrosine, derived from diet and endogenous proteins and peptides, can be converted to phenol and 4-hydroxyphenylpyruvate.

    Drugs: Pyridoxal phosphate · Tyrosine · Glutamic acid · P-Cresol · Oxogluric acid · 4-Hydroxyphenylpyruvic acid
  9. Drug

    Piracetam

    go.drugbank.com/drugs/DB09210
    ApprovedWithdrawn

    In the UK, piracetam is prescribed mainly for myoclonus, but is used off-label for other conditions such as learning difficulties in children, memory loss or other cognitive defects in the elderly, and … It is not approved for any medical or dietary use by the FDA.

    Categories: Psychostimulants, Agents Used for ADHD and Nootropics, Compounds used in a research, industrial, or household settingProducts: NOTROSERB 1 G IM/IV ENJEKSİYONLUK ÇÖZELTİ , 100 ADET, NOTROSERB 1 G IM/IV ENJEKSİYONLUK ÇÖZELTİ , 12 ADET
  10. Drug

    Cod liver oil

    go.drugbank.com/drugs/DB11321
    ApprovedNutraceuticalVet approved

    It is used as an adjunct treatment and preventative therapy of rickets, osteomalacia and osteoporosis while meeting the consumption criteria. … Also being a rich source of vitamin A and D, cod liver oil can be taken orally as daily supplements.

    Mixtures: CURACID Dermal for cuts and burnsCategories: Diet, Food, and Nutrition