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Displaying results 1 - 10 of 509 in total
  1. Target

    Sodium- and chloride-dependent betaine transporter

    go.drugbank.com/bio_entities/BE0004777
    TargetTransporterHumans

    Transporter that mediates cellular uptake of betaine and GABA in a sodium- and chloride-dependent process (PubMed:7589472). … Probably also involved in renal and hepatic osmotic regulation (By similarity)

    Polypeptides: Sodium- and chloride-dependent betaine transporter
  2. Target

    Sodium- and chloride-dependent taurine transporter

    go.drugbank.com/bio_entities/BE0009148
    TransporterHumans

    Mediates sodium- and chloride-dependent transport of taurine, a key amino acid (PubMed:31345061, PubMed:31903486, PubMed:39837997, PubMed:40108165, PubMed:40108449, PubMed:40615403, PubMed:40789850, PubMed … Taurine acts as an anti-aging agent by reducing cellular senescence and combating oxidative stress: levels decline with age and supplementation has been shown to extend lifespan (By similarity).

    Polypeptides: Sodium- and chloride-dependent taurine transporter
  3. Target

    Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)

    go.drugbank.com/bio_entities/BE0000423
    TargetTransporterHumans

    Transports non-alpha-amino acids such as beta-alanine with low affinity, and has a higher affinity for dipolar and cationic amino acids such as leucine and lysine (PubMed:18599538). … Can also transport carnitine, butirylcarnitine and propionylcarnitine coupled to the transmembrane gradients of Na(+) and Cl(-) (PubMed:17855766)

    Polypeptides: Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)
  4. Target

    Sodium- and chloride-dependent GABA transporter 1

    go.drugbank.com/bio_entities/BE0000249
    TargetHumans

    Mediates transport of gamma-aminobutyric acid (GABA) together with sodium and chloride and is responsible for the reuptake of GABA from the synapse (PubMed:30132828). … Can also mediate sodium- and chloride-dependent transport of hypotaurine but to a much lower extent as compared to GABA (By similarity)

    Polypeptides: Sodium- and chloride-dependent GABA transporter 1
  5. Target

    Sodium- and chloride-dependent creatine transporter 1

    go.drugbank.com/bio_entities/BE0000375
    TargetTransporterHumans

    Plays an important role in supplying creatine to the brain via the blood-brain barrier (By similarity)

    Polypeptides: Sodium- and chloride-dependent creatine transporter 1
  6. Target

    Sodium- and chloride-dependent GABA transporter 2

    go.drugbank.com/bio_entities/BE0004776
    TargetHumans

    Mediates sodium- and chloride-dependent transport of gamma-aminobutyric acid (GABA) (PubMed:17502375, PubMed:22932902). Mediates transport of beta-alanine (PubMed:17502375). … Can also mediate transport of taurine and hypotaurine (By similarity)

    Polypeptides: Sodium- and chloride-dependent GABA transporter 2
  7. Target

    Sodium- and chloride-dependent glycine transporter 1

    go.drugbank.com/bio_entities/BE0000940
    TransporterTargetHumans

    Sodium- and chloride-dependent glycine transporter (PubMed:37962965, PubMed:8183239). Essential for regulating glycine concentrations at inhibitory glycinergic synapses

    Polypeptides: Sodium- and chloride-dependent glycine transporter 1
  8. Target

    Sodium- and chloride-dependent glycine transporter 2

    go.drugbank.com/bio_entities/BE0002310
    TransporterTargetHumans

    Sodium- and chloride-dependent glycine transporter (PubMed:10381548, PubMed:10606742, PubMed:16751771, PubMed:31370103, PubMed:9845349). … Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals (PubMed:9845349).

    Polypeptides: Sodium- and chloride-dependent glycine transporter 2
  9. Target

    Sodium- and chloride-dependent GABA transporter 3

    go.drugbank.com/bio_entities/BE0004733
    TargetHumans

    Mediates sodium- and chloride-dependent transport of gamma-aminobutyric acid (GABA) (PubMed:7874447). … Can also mediate transport of beta-alanine and to a lower extent that of taurine and hypotaurine (By similarity)

    Polypeptides: Sodium- and chloride-dependent GABA transporter 3
  10. Target

    Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide

    go.drugbank.com/bio_entities/BE0001300
    TargetHumans

    May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K

    Polypeptides: Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide