Search
Glycine betaine/proline betaine-binding periplasmic protein
go.drugbank.com/bio_entities/BE0002045TargetTransporterEscherichia coli (strain K12)Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake. Binds glycine betaine and proline betaine with high affinity.
Polypeptides: Glycine betaine/proline betaine-binding periplasmic proteinSynonyms: Glycine betaine-binding periplasmic proteinBetaine--homocysteine S-methyltransferase 1
go.drugbank.com/bio_entities/BE0000845TargetHumansConverts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline
Polypeptides: Betaine--homocysteine S-methyltransferase 1Function: betaine-homocysteine S-methyltransferase activitySodium- and chloride-dependent betaine transporter
go.drugbank.com/bio_entities/BE0004777TargetTransporterHumansTransporter that mediates cellular uptake of betaine and GABA in a sodium- and chloride-dependent process (PubMed:7589472).
Polypeptides: Sodium- and chloride-dependent betaine transporterSynonyms: Na(+)/Cl(-) betaine/GABA transporterS-methylmethionine--homocysteine S-methyltransferase BHMT2
go.drugbank.com/bio_entities/BE0002249TargetEnzymeHumansInvolved in the regulation of homocysteine metabolism. Converts homocysteine to methionine using S-methylmethionine (SMM) as a methyl donor
Synonyms: Betaine--homocysteine S-methyltransferase 2Alpha-aminoadipic semialdehyde dehydrogenase
go.drugbank.com/bio_entities/BE0000135TargetHumansInvolved in cellular defense against hyperosmotic stress by metabolizing betaine aldehyde to betaine, an important cellular osmolyte and methyl donor (PubMed:20207735)
Synonyms: Betaine aldehyde dehydrogenaseGamma-butyrobetaine dioxygenase
go.drugbank.com/bio_entities/BE0002197TargetEnzymeHumansCatalyzes the formation of L-carnitine from gamma-butyrobetaine
Choline dehydrogenase, mitochondrial
go.drugbank.com/bio_entities/BE0000636EnzymeHumansCatalyzes the dehydrogenation of choline to betaine aldehyde in the mitochondria (By similarity). Involved in mitochondrial autophagy after mitochondrial damage (PubMed:25483962)
Flavin-containing monooxygenase 3
go.drugbank.com/bio_entities/BE0003606EnzymeHumansTMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine.
Flavin-containing monooxygenase 1
go.drugbank.com/bio_entities/BE0003609EnzymeHumansTMAO) and could therefore participate to the detoxification of this compound that is generated by the action of gut microbiota from dietary precursors such as choline, choline containing compounds, betaine
Y+L amino acid transporter 2
go.drugbank.com/bio_entities/BE0009872TransporterHumansMay also transport glycine betaine in a sodium dependent manner from the cumulus granulosa into the enclosed oocyte (By similarity)