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Mepyramine H1-Antihistamine Action
smpdb.ca/view/SMP0057583Drug actionMepyramine (pyrilamine) is a first-generation ethylenediamine H1-antihistamine.
Mepyramine H1-Antihistamine Immune Response Action Pathway
smpdb.ca/view/SMP0175094Drug actionMepyramine is an antihistamine agent used for the symptomatic treatment of allergy, hypersensitivity reactions, and pruritic skin disorders. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are admi...
Mepyramine H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0175002Drug actionMepyramine is an antihistamine agent used for the symptomatic treatment of allergy, hypersensitivity reactions, and pruritic skin disorders. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are admi...
Mepyramine H1 Antihistamine Neurological Sleep Action Pathway
smpdb.ca/view/SMP0145417Drug actionMepyramine is an ethanolamine class H1 antihistamine used to treat insomnia and allergy symptoms such as hay fever and hives. It is also used with pyridoxine in the treatment of nausea and vomiting in pregnancy. H1-antihistamines interfe...
Mepyramine H1 Antihistamine Smooth Muscle Relaxation Action Pathway
smpdb.ca/view/SMP0174910Drug actionMepyramine is an antihistamine agent used for the symptomatic treatment of allergy, hypersensitivity reactions, and pruritic skin disorders. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are admi...
Caffeine Metabolism
smpdb.ca/view/SMP0000028MetabolicCaffeine is obtained from diet including coffee and other beverages and is absorbed in the stomach and small intestine. In the liver, the cytochrome P450 oxidase enzyme system and specifically CYP1A2 metabolizes caffeine into paraxanthin...
Drugs: NADH · Caffeine · Theophylline · Theobromine · Mesoheme · Flavin adenine dinucleotide +1 moreAcetaminophen Metabolism Pathway
smpdb.ca/view/SMP0000640Drug metabolismAcetaminophen (APAP) is metabolized primarily in the liver. Glucuronidation is the main route, accounting for 45-55% of APAP metabolism, and is mediatied by UGT1A1, UGT1A6, UGT1A9, UGT2B15 in the liver and UGT1A10 in the gut. APAP can al...
Acetaminophen Action Pathway (New)
smpdb.ca/view/SMP0122823Drug actionAcetaminophen is an oral/IV antipyretic and analgesic drug used to treat fevers and mild to moderate pain. Its exact mechanism is unknown but it is thought to target the cyclooxygenase pathway in the CNS (brain). It does not inhibit the ...
Caffeine Vasodilation Action Pathway
smpdb.ca/view/SMP0125283Drug actionCaffeine is a stimulant present in tea, coffee, cola beverages, analgesic drugs, and agents used to increase alertness. The cardiovascular effects are extensive and can help with headaches, migraines, or other types of pain in certain ci...
Caffeine Nervous Action Pathway
smpdb.ca/view/SMP0125297Drug actionCaffeine is a central nervous system stimulant present in tea, coffee, cola beverages, analgesic drugs, and agents used to increase alertness. Consistent intake of caffeine increases the population of adenosine receptors, which can poten...
Drugs: Pyridoxal phosphate · Glutamic acid · Caffeine · Norepinephrine · Adenosine · Calcium +1 more