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Ciclesonide
go.drugbank.com/drugs/DB01410
ApprovedInvestigational
Ciclesonide is a glucocorticoid used to treat obstructive airway diseases. It is marketed under the brand name Alvesco.
Ciclesonide Action Pathway
smpdb.ca/view/SMP0126184Drug actionCiclesonide is a pro-drug so it is enzymatically hydrolyzed to C21-desisobutyryl-ciclesonide (des-ciclesonide or RM1), the active metabolite. … Des-ciclesonide has anti-inflammatory activity with an affinity for the glucocorticoid receptor that is 120 times higher than ciclesonide.
Bronchoconstriction
go.drugbank.com/conditions/DBCOND0020847Perennial Allergic Rhinitis (PAR)
go.drugbank.com/conditions/DBCOND0058482Drugs: Azelastine · Beclomethasone dipropionate · Cetirizine · Ciclesonide · Cortisone acetate · Cromoglicic acid +12 moreSeasonal Allergic Rhinitis
go.drugbank.com/conditions/DBCOND0030588Drugs: Acrivastine · Azelastine · Beclomethasone dipropionate · Bilastine · Cetirizine · Ciclesonide +22 moreChronic Obstructive Pulmonary Disease (COPD)
go.drugbank.com/conditions/DBCOND0031289Asthma
go.drugbank.com/conditions/DBCOND0013565Drugs: Albuterol · Ambrosia artemisiifolia pollen · Aminophylline · Arformoterol · Beclomethasone dipropionate · Budesonide +39 more