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Displaying drugs 251 - 275 of 13657 in total

Oxybutynin

Overactive bladder (OAB) is a common condition negatively impacting the lives of millions of patients worldwide. Due to its urinary symptoms that include nocturia, urgency, and frequency, this condition causes social embarrassment and a poor quality of life.[A185996,A185999] Oxybutynin, also marketed as Ditropan XL, is an anticholinergic medication used for...
Approved
Investigational
Matched Description: … the relief of overactive bladder symptoms that has been optimized for high levels of safety and efficacy ... since initial FDA approval in 1975. ... Overactive bladder (OAB) is a common condition negatively impacting the lives of millions of patients …
Matched Categories: … Drugs for Urinary Frequency and Incontinence …
Matched Products: … Oxytrol For Women ... Oxytrol for Women …

Certolizumab pegol

Certolizumab pegol is a pegylated monoclonal antibody against the tumor necrosis factor-alpha (TNF-alpha). It is formed with a humanized Fab fragment of 50 kDa, from an IgG 1 isotype, fused to a 40 kDa polyethylene glycol moiety replacing the Fc antibody region. The absence of the Fc region was ideated...
Approved
Matched Description: … for a new indication on March 28, 2019. ... [A176585] It is formed with a humanized Fab fragment of 50 kDa, from an IgG 1 isotype, fused to a 40 ... [A176606] Certolizumab does not require glycosylation for active function and hence, its production …
Matched Categories: … Agents reducing cytokine levels ... Biologics for Rheumatoid Arthritis Treatment …
Matched Products: … CIMZIA 200 MG ILO IN FER ... CIMZIA 200MG ILO IN FER …

Panthenol

Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Panthenol exists as a racemic mixture containing both the dextrorotatory form (dexpanthenol) and the levorotatory form (levopanthenol). While pantothenic acid is optically active, only the dextrorotatory...
Approved
Matched Description: … that acts as a cofactor in many enzymatic reactions that are important for protein metabolism in the ... , such as ointments and lotions for treatment of dermatological conditions to relieve itching or promote ... essential component of a normally functioning epithelium. …
Matched Mixtures name: … ReEn Mogangbichaek for Sensitive Scalp ... All New TS ... ReEn Hairloss Clinic Jahajin Shampoo for Sensitive Scalp …
Matched Products: … Roota Re F for men ... Roota Re V for women …

Cetrorelix

Cetrorelix is a man-made hormone that blocks the effects of Gonadotropin Releasing Hormone (GnRH). GnRH controls another hormone that is called luteinizing hormone (LH), which is the hormone that starts ovulation during the menstrual cycle. When undergoing hormone treatment sometimes premature ovulation can occur, leading to eggs that are not...
Approved
Investigational
Matched Description: … Cetrorelix is a man-made hormone that blocks the effects of Gonadotropin Releasing Hormone (GnRH). ... undergoing hormone treatment sometimes premature ovulation can occur, leading to eggs that are not ready for …
Matched Products: … Cetrotide 0.25 mg powder and solvent for solution for injection …

Ceftriaxone

Ceftriaxone is a broad-spectrum third-generation cephalosporin antibiotic. It has a very long half-life compared to other cephalosporins and is high penetrable into the meninges , eyes , and inner ear . Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins, but worse activity against methicillin-susceptible S.aureus. Ceftriaxone...
Approved
Matched Description: … , its relatively safe adverse effect profile, and its long half-life which allows for the convenience ... Ceftriaxone is a broad-spectrum third-generation cephalosporin antibiotic. ... [A215582] It has a very long half-life compared to other cephalosporins and is high penetrable into the …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … CEFTRIAXONA 1000 MG POLVO ESTERIL PARA RECONSTITUIR A SOLUCION INYECTABLE. ... CYROSEF POWDER FOR SOLUTION FOR INJECTION 2GM ... CYROSEF POWDER FOR SOLUTION FOR INJECTION 1GM …

Isoniazid

Antibacterial agent used primarily as a tuberculostatic. It remains the treatment of choice for tuberculosis.
Approved
Investigational
Matched Description: … It remains the treatment of choice for tuberculosis. ... Antibacterial agent used primarily as a tuberculostatic. …
Matched Categories: … Antiinfectives for Systemic Use ... Drugs for Treatment of Tuberculosis …

Sodium phosphate, monobasic

Sodium phosphate is a saline laxative that is thought to work by increasing fluid in the small intestine. It usually results in a bowel movement after 30 minutes to 6 hours.
Approved
Matched Description: … It usually results in a bowel movement after 30 minutes to 6 hours. ... Sodium phosphate is a saline laxative that is thought to work by increasing fluid in the small intestine …
Matched Mixtures name: … FLEET ENEMA FOR CHILDREN ... OMEGA PLUS EMULSION FOR INFUSION ... Instillation Medium for Immucyst …
Matched Categories: … Drugs for Constipation ... Drugs for Treatment of Hypercalcemia …

Abemaciclib

Abemaciclib is an antitumor agent and dual inhibitor of cyclin-dependent kinases 4 (CDK4) and 6 (CDK6) that are involved in the cell cycle and promotion of cancer cell growth in case of unregulated activity. On September 28, 2017, FDA granted approval of abemaciclib treatment under the market name Verzenio for...
Approved
Investigational
Matched Description: … On September 28, 2017, FDA granted approval of abemaciclib treatment under the market name Verzenio for ... of cancer, or in combination with [DB00947]. ... the cell cycle and promotion of cancer cell growth in case of unregulated activity. …
Matched Categories: … MATE 1 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …

Povidone

Povidone, also known as polyvinylpyrrolidone (PVP) or polyvidone, is a synthetic water-soluble polymer made from the monomer N-vinylpyrrolidone used as a binder in many pharmaceutical tablets and lubricant in eye drops. It is also used in many technical applications with various roles as an adhesive, additive, and emulsifier. When in...
Approved
Withdrawn
Matched Description: … The FDA withdrew its approval for the use of all intravenous drug products containing povidone. ... made from the monomer N-vinylpyrrolidone used as a binder in many pharmaceutical tablets and lubricant ... When in complex with iodine, [DB06812] displays antiseptic properties where the iodine, a bactericidal …
Matched Mixtures name: … Visine for Red Eye Cool ... Murine Tears for Dry Eyes ... Visine for Red Eye Workplace …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … iVizia Lubricant Eye for Severe Night Dry Eyes …

Amlexanox

Amlexanox is an antiallergic drug, clinically effective for atopic diseases, especially allergic asthma and rhinitis. Amlexanox as a topical paste is a well tolerated treatment of recurrent aphthous ulcers. Recurrent aphthous ulcer (RAU) is the most prevalent oral mucosal disease in humans, estimated to affect between 5% and 50% of...
Approved
Investigational
Withdrawn
Matched International brands: … OraDisc A …
Matched Description: … Amlexanox as a topical paste is a well tolerated treatment of recurrent aphthous ulcers. ... Amlexanox is an antiallergic drug, clinically effective for atopic diseases, especially allergic asthma ... Recurrent aphthous ulcer (RAU) is the most prevalent oral mucosal disease in humans, estimated to affect …
Matched Categories: … Drugs for Obstructive Airway Diseases …

Sevelamer

Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. It is marketed by Genzyme under the trade name Renagel.
Approved
Matched Description: … Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
Matched Products: … Sevelamer Carbonate for Oral Suspension ... Sevelamer Carbonate For Oral Suspension …

Flurbiprofen

Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen may also be used topically prior to ocular surgery to prevent or reduce intraoperative miosis....
Approved
Investigational
Matched Description: … Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic ... Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, …
Matched Categories: … Topical Products for Joint and Muscular Pain ... Antiinflammatory Preparations, Non-Steroids for Topical Use …
Matched Products: … STREPSILS INTENSIVE SOLUCION EN SPRAY SABOR A MIEL Y LIMON ... Strepsils 8,75 mg/Dosis Spray zur Anwendung in der Mundhöhle, Lösung ... Strepsils Honig & Zitrone 8,75 mg/Dosis Spray zur Anwendung in der Mundhöhle, Lösung …

Hydralazine

Originally developed in the 1950s as a malaria treatment, hydralazine showed antihypertensive ability and was soon repurposed. Hydralazine is a hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment of hypertension and only as adjunct therapy in the treatment of heart failure.[A186820,L8782,L8785] Hydralazine is no longer a...
Approved
Matched Description: … [A186820,L8782,L8785] Hydralazine is no longer a first line therapy for these indications since the development ... Originally developed in the 1950s as a malaria treatment, hydralazine showed antihypertensive ability ... [A186841] Hydralazine is a hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment …
Matched Categories: … Medications that reduce magnesium levels ... Antihypertensive Agents Indicated for Hypertension …
Matched Products: … APRESOLINE FOR INJECTION 20 mg/ampoule …

Pamidronic acid

Pamidronic acid is a second generation, nitrogen containing bisphosphonate similar to neridronic acid and alendronic acid. Pamidronic acid was first described in the literature in 1977. The second generation bisphosphonates are less common as third generation bisphosphonates, such as ibandronic acid, zoledronic acid, minodronic acid, and risedronic acid are becoming...
Approved
Matched Description: … [A203111] Pamidronic acid was first described in the literature in 1977. ... Pamidronic acid is a second generation, nitrogen containing bisphosphonate similar to [neridronic acid …
Matched Categories: … Drugs for Treatment of Bone Diseases ... Medications that reduce magnesium levels …
Matched Products: … Pamidronate Disodium for Injection …

Moroctocog alfa

Moroctocog alfa, also known as BDDrFVIII (B domain deleted recombinant factor VIII), is a recombinant DNA-based drug with functional characteristics comparable to those of endogenous coagulation Factor VIII, the essential human blood clotting protein that is impaired in Hemophilia A. Moroctocog alfa is identical in sequence to endogenously produced Factor...
Approved
Matched Description: … the body due to its involvement in the clotting cascade where it is responsible for acting as a co-factor ... Replacement of Factor VIII is essential for the treatment of Hemophilia A, which is caused by mutations ... prevention of hemorrhagic episodes and for routine and surgical prophylaxis in patients with hemophilia …
Matched Products: … Xyntha 250 IU Powder and Solvent for Solution for Injection ... Xyntha 1000 IU Powder and Solvent for Solution for Injection ... Xyntha 500 IU Powder and Solvent for Solution for Injection …

Fexinidazole

Human African trypanosomiasis (HAT, also colloquially referred to as sleeping sickness), caused by T. brucei gambiense and T. brucei rhodesiense, remains a moderate risk (>1/10,000 inhabitants per year in endemic areas) despite focussed control efforts. Transmitted by the bite of an infected tsetse fly, HAT is biphasic with a first...
Approved
Investigational
Matched Description: … rediscovered through the Drugs for Neglected Diseases Initiative (DNDi) in 2005, is the first all-oral ... that progresses to a second (meningoencephalitic) stage in which patients experience progressively worsening ... treatment for first and second stage HAT caused by _T. brucei gambiense_. …

Linoleic acid

Approved
Experimental
Matched Synonyms: … all-cis-9,12-octadecadienoic acid …

Permethrin

A pyrethroid insecticide commonly used in the treatment of lice infestations and scabies. It is a yellow to light orange-brown, low melt-ing solid or viscous liquid.
Approved
Investigational
Matched Description: … A pyrethroid insecticide commonly used in the treatment of lice infestations and scabies. ... It is a yellow to light orange-brown, low melt-ing solid or viscous liquid. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … A Scabs ... A-LICES LOTION 1%w/w …

Cisatracurium

Cisatracurium is a non-depolarising neuromuscular blocking agent of the benzylisoquinolinium class, available in its salt form, cisatracurium besylate.[A243416,A253592] Cisatracurium has an intermediate duration of action and is one of the most commonly used neuromuscular blocking agents in intensive care.[A253592,A253597]. Cisatracurium acts on cholinergic receptors, blocking neuromuscular transmission. This action is...
Approved
Investigational
Matched Description: … in its salt form, cisatracurium besylate. ... [A243416] Compared to atracurium, cisatracurium produces a lower degree of histamine release. ... Cisatracurium is a non-depolarising neuromuscular blocking agent of the benzylisoquinolinium class, available …
Matched Products: … Cisatracurium-hameln 2 mg/ml solution for injection/infusion ... Cisatracurium Kabi 2 mg/ml solution for injection or infusion …

Darunavir

Darunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as ritonavir for the effective management of HIV-1 infection. As a second-generation protease inhibitor, darunavir is designed to combat resistance to standard HIV therapy.[A2278,A2281] It was initially approved by the FDA in 2006. Darunavir is being...
Approved
Matched Description: … for COVID-19, due to in vitro evidence supporting its ability to combat this infection. ... [L9227] Darunavir is being studied as a possible treatment for SARS-CoV-2, the coronavirus responsible ... for the effective management of HIV-1 infection. …
Matched Categories: … Antivirals used in combination for the treatment of HIV infections ... Antivirals for Systemic Use ... Antiinfectives for Systemic Use ... Experimental Unapproved Treatments for COVID-19 …

Fosaprepitant

Fosaprepitant is an intravenously administered antiemetic drug. It is a prodrug of Aprepitant. It aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment.
Approved
Matched Description: … It is a prodrug of Aprepitant. ... It aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment …
Matched Products: … Powder for Solution for Infusion 150mg ... APRITANT IV® 150 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE …

Antithymocyte immunoglobulin (rabbit)

Rabbit anti-thymocyte globulin. Thymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for acute organ rejection in transplant patients. Thymoglobulin is a mixture of antibodies intended to bind to various cell surface antigens. The most common mode of action of Thymoglobulin is via selective depletion of...
Approved
Matched Description: … Thymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for ... acute organ rejection in transplant patients. ... Thymoglobulin is a mixture of antibodies intended to bind to various cell surface antigens. …
Matched Products: … Thymoglobuline 5mg/ml Powder for concentrate for solution for infusion …

Tetryzoline

Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral alpha (α)-adrenergic properties. Available since the 1950s, tetryzoline is a selective α1-receptor agonist that is used as an ocular and nasal decongestant. Tetryzoline is found in a wide array of over-the-counter eye drops, including the most...
Approved
Matched Description: … [A7045, A231769] It has also been misused for non-therapeutic purposes as a causative drug for several ... Tetryzoline is found in a wide array of over-the-counter eye drops, including the most common brand, ... Tetryzoline is also found in nasal spray under the trade name Tyzine, which is used for decongestion …
Matched Mixtures name: … Rohto All-In-One ... ISCHEMOL A ... ISCHEMOL A …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Pregabalin

Pregabalin is structurally similar to gamma-aminobutyric acid (GABA) - an inhibitory neurotransmitter. It may be used to manage neuropathic pain, postherpetic neuralgia, and fibromyalgia among other conditions. Although as per the FDA Label the mechanism of action has not been definitively characterized, there is evidence that pregabalin exerts its effects...
Approved
Investigational
Matched Description: … [L1006,L7066] It may have dependence liability if misused but the risk appears to be highest in patients …
Matched Products: … PREGABALIN 1 A PHARMA 25MG ... PREGABALIN 1 A PHARMA 75MG ... PREGABALIN 1 A PHARMA200MG …

Lithium citrate

Approved
Displaying drugs 251 - 275 of 13657 in total