Displaying drugs 3201 - 3225 of 12063 in total
Cephaloglycin
A cephalorsporin antibiotic that is no longer commonly used.
Approved
Matched Description: … A cephalorsporin antibiotic that is no longer commonly used. …
Lenvatinib
Lenvatinib is a receptor tyrosine kinase (RTK) inhibitor that inhibits the kinase activities of vascular endothelial growth factor (VEGF) receptors VEGFR1 (FLT1), VEGFR2 (KDR), and VEGFR3 (FLT4). Lenvatinib also inhibits other RTKs that have been implicated in pathogenic angiogenesis, tumor growth, and cancer progression in addition to their normal cellular...
Approved
Investigational
Matched Description: … Lenvatinib is a receptor tyrosine kinase (RTK) inhibitor that inhibits the kinase activities of vascular ... and increased expression of VEGF is associated with a poor prognosis in many types of cancers. ... Most patients with thyroid cancer have a very good prognosis with treatment (98% 5 year survival rate …
Butalbital
Butalbital, or 5-allyl-5-isobutylbarbituric acid, is a derivative of barbituric acid which the hydrogens at position 5 are substituted by an allyl group and an isobutyl group. It is a short-to-intermediate acting member of barbiturates that exhibit muscle-relaxing and anti-anxiety properties that produce central nervous system (CNS) depression that ranges from...
Approved
Illicit
Matched Description: … [A177754] Butalbital has a low degree of selectivity and a narrow therapeutic index. ... Butalbital, or 5-allyl-5-isobutylbarbituric acid, is a derivative of barbituric acid which the hydrogens ... It is a short-to-intermediate acting member of barbiturates that exhibit muscle-relaxing and anti-anxiety …
Methotrimeprazine
A phenothiazine with pharmacological activity similar to that of both chlorpromazine and promethazine. It has the histamine-antagonist properties of the antihistamines together with central nervous system effects resembling those of chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed, p604)
Approved
Investigational
Matched Description: … A phenothiazine with pharmacological activity similar to that of both chlorpromazine and promethazine …
Bicisate
Bicisate, also known as ethyl cysteinate dimer (ECD), is a N,N'-1,2-ethylene-di-yl-bis-L-cysteinate diethyl ester. It is used in conjunction with technetium Tc99m as a tracer to measure cerebral blood flow with single-photon emission computed tomography (SPECT). The complex of bicisate and technetium Tc99m as a kit was developed by Lantheus Medcl...
Approved
Investigational
Matched Description: … Bicisate, also known as ethyl cysteinate dimer (ECD), is a N,N'-1,2-ethylene-di-yl-bis-L-cysteinate diethyl ... It is used in conjunction with technetium Tc99m as a tracer to measure cerebral blood flow with single-photon ... [A32374] The complex of bicisate and technetium Tc99m as a kit was developed by Lantheus Medcl and FDA-approved …
Enoximone
Enoximone is a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity that does not cause changes in myocardial oxygen consumption. It is used in patients with congestive heart failure. Trials were halted in the U.S., but the drug is used in various countries.
Approved
Investigational
Matched Description: … Enoximone is a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Sodium tetradecyl sulfate
An anionic surface-active agent used for its wetting properties in industry and used in medicine as an irritant and sclerosing agent for hemorrhoids and varicose veins.
Approved
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …
Albumin Aggregated
Albumin aggregated is an ingredient in the DRAXIMAGE MAA kit for the preparation of technetium tc99m albumin aggregated injection. This imaging agent is used to assess lung perfusion and for the evaluation of peritoneovenous (LeVeen) shunt patency.
Approved
Arzoxifene
Approved
Investigational
Amorolfine
Amorolfine or amorolfin, is a morpholine antifungal drug that inhibits the fungal enzymes D14 reductase and D7-D8 isomerase. This inhibition affects fungal sterol synthesis pathways, depleting ergosterol and causing ignosterol to accumulate in the fungal cytoplasmic cell membranes. Amorolfine is marketed as Curanail, Loceryl, Locetar, and Odenil. It is available...
Approved
Investigational
Matched Description: … It is a topical solution for the treatment of toenail infections. ... Amorolfine or amorolfin, is a morpholine antifungal drug that inhibits the fungal enzymes D14 reductase ... It is available in the form of a 5% amorolfine nail lacquer used to treat onychomycosis (fungal infection …
Amylocaine
Despite the introduction of using cocaine injections for regional anesthesia in 1884, non-addictive substitutes were sought after immediately . Finally, in 1903 the world's first synthetic and non-addictive local anesthetic, amylocaine, was synthesized and patented under the name Forneaucaine by Ernest Fourneau at the Pasteur Institute . Elsewhere in English...
Approved
Withdrawn
Adiphenine
Approved
Withdrawn
Alfentanil
A short-acting opioid anesthetic and analgesic derivative of fentanyl. It produces an early peak analgesic effect and fast recovery of consciousness. Alfentanil is effective as an anesthetic during surgery, for supplementation of analgesia during surgical procedures, and as an analgesic for critically ill patients.
Approved
Illicit
Matched Description: … A short-acting opioid anesthetic and analgesic derivative of fentanyl. …
Imelasomeran
Imelasomeran was first approved in Canada on September 1, 2022, as one-half of Moderna's Spikevax Bivalent COVID-19 mRNA vaccine. It encodes for the viral spike protein of the Omicron BA.1 variant of SARS-CoV-2, a particularly infectious variant of concern first documented in 2021.
Approved
Investigational
Matched Description: … [L45320] It encodes for the viral spike protein of the Omicron BA.1 variant of SARS-CoV-2, a particularly …
Diflorasone
Diflorasone is a topical corticosteroid used to treat itching and inflammation of the skin.
Approved
Matched Iupac: … dihydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Diflorasone is a topical corticosteroid used to treat itching and inflammation of the skin. …
Matched Description: … Diflorasone is a topical corticosteroid used to treat itching and inflammation of the skin. …
Alclometasone
Alclometasone is synthetic glucocorticoid steroid for topical use in dermatology as anti-inflammatory, antipruritic, antiallergic, antiproliferative and vasoconstrictive agent.
Approved
Matched Iupac: … dihydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Mifepristone
Mifepristone is a progestational and glucocorticoid hormone antagonist. Its inhibition of progesterone induces bleeding during the luteal phase and in early pregnancy by releasing endogenous prostaglandins from the endometrium or decidua. As a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients with nonpituitary cushing syndrome....
Approved
Investigational
Matched Iupac: … phenyl]-1-hydroxy-11a-methyl-1-(prop-1-yn-1-yl)-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Mifepristone is a progestational and glucocorticoid hormone antagonist. ... As a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients …
Matched Description: … Mifepristone is a progestational and glucocorticoid hormone antagonist. ... As a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients …
Fluocortolone
Fluocortolone is a glucocorticoid with anti-inflammatory activity used topically for various skin disorders.
Approved
Withdrawn
Matched Iupac: … hydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Fluocortolone is a glucocorticoid with anti-inflammatory activity used topically for various skin disorders …
Matched Description: … Fluocortolone is a glucocorticoid with anti-inflammatory activity used topically for various skin disorders …
Prednisolone phosphate
Prednisolone phosphate is a glucocorticoid similar to cortisol used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. Prednisolone phosphate was granted FDA Approval on 19 December 1973.
Approved
Vet approved
Matched Iupac: … 11aS)-1,10-dihydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Prednisolone phosphate is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive …
Matched Description: … Prednisolone phosphate is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive …
Temozolomide
Refractory anaplastic astrocytoma (WHO grade III) and Glioblastoma multiforme (WHO grade IV) are primary malignant brain tumours with poor prognosis and limited treatment options. Despite considerable genetic heterogeneity, these tumours often have impaired DNA repair systems, rendering them initially sensitive to alkylating agents, although they invariably develop resistance to these...
Approved
Investigational
Matched Description: … [A229853, A229888, A229923, L32033] Following initial hydrolysis, further reactions liberate a highly …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index …
Technetium Tc-99m oxidronate
Technetium Tc-99m oxidronate, also known as 99mTc-methylene diphosphonate, is a radiopharmaceutical agent. A radiopharmaceutical is defined as a medicinal formulation containing radioisotopes that are used in major clinical areas for diagnosis and/or therapy. The radiopharmaceuticals based on technetium-99m are widely used for diagnostic purposes because 99mTc has a versatile chemistry...
Approved
Matched Description: … A radiopharmaceutical is defined as a medicinal formulation containing radioisotopes that are used in ... Technetium Tc-99m oxidronate, also known as 99mTc-methylene diphosphonate, is a radiopharmaceutical agent ... [L1139] Thus, technetium Tc-99m oxidronate is a powerful detection tool for abnormal osteogenesis by …
Tirofiban
Tirofiban prevents the blood from clotting during episodes of chest pain or a heart attack, or while the patient is undergoing a procedure to treat a blocked coronary artery. It is a non-peptide reversible antagonist of the platelet glycoprotein (GP) IIb/IIIa receptor, and inhibits platelet aggregation.
Approved
Matched Description: … the patient is undergoing a procedure to treat a blocked coronary artery. ... Tirofiban prevents the blood from clotting during episodes of chest pain or a heart attack, or while ... It is a non-peptide reversible antagonist of the platelet glycoprotein (GP) IIb/IIIa receptor, and inhibits …
alpha-Linolenic acid
Alpha-linolenic acid (ALA) is a polyunsaturated omega-3 fatty acid. It is a component of many common vegetable oils and is important to human nutrition.
Approved
Investigational
Nutraceutical
Matched Description: … Alpha-linolenic acid (ALA) is a polyunsaturated omega-3 fatty acid. ... It is a component of many common vegetable oils and is important to human nutrition. …
Piracetam
Piracetam is a nootropic drug in the racetams group, with chemical name 2-oxo-1-pyrrolidine acetamide. It shares the same 2-oxo-pyrrolidone base structure with pyroglutamic acid and is a cyclic derivative of the neurotransmitter γ-aminobutyric acid (GABA). However its mechanism of action differ from that of endogenous GABA. Piracetam has neuroprotective and...
Approved
Investigational
Matched Description: … Piracetam is a nootropic drug in the racetams group, with chemical name 2-oxo-1-pyrrolidine acetamide ... It shares the same 2-oxo-pyrrolidone base structure with pyroglutamic acid and is a cyclic derivative …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Iofetamine I-123
Approved
Matched Categories: … Compounds used in a research, industrial, or household setting …
Displaying drugs 3201 - 3225 of 12063 in total