Displaying drugs 3376 - 3400 of 11612 in total
Kaolin
Kaolin is a layered silicate mineral. Kaolin is used in ceramics, medicine, coated paper, as a food additive, in toothpaste, as a light diffusing material in white incandescent light bulbs, and in cosmetics. Until the early 1990s it was the active substance of anti-diarrhoea medicine Kaopectate.
Approved
Matched Description: … Kaolin is a layered silicate mineral. ... Kaolin is used in ceramics, medicine, coated paper, as a food additive, in toothpaste, as a light diffusing …
Birch bark extract
Birch bark extract is rich in triterpenoids with beneficial biological and pharmacological activities. Some of the compounds identified in it include betulin, lupeol, betulinic acid, oleanolic acid, and erythrodiol. Birch bark extract is obtained from the white part of the birch tree bark, and the main species of trees used...
Approved
Experimental
Matched Description: … approved for the treatment of partial thickness wounds in patients with epidermolysis bullosa (EB), a …
Xenon Xe-129
Hyperpolarized Xenon-129 (Xe-129) is a contrast agent used in the lung's clinical magnetic resonance imaging (MRI). Lung MRIs are challenging due to the low proton density of this tissue, as well as the presence of artifacts due to respiration and cardiovascular pulsation movement and air–tissue interfaces.[A255178,A255183] The use of hyperpolarized...
Approved
Matched Description: … a higher MRI signal. ... Hyperpolarized Xenon-129 (Xe-129) is a contrast agent used in the lung's clinical magnetic resonance ... They undergo a process that increases nuclear polarization up to five orders of magnitude, leading to …
Bromfenac
Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. Their well-characterized anti-inflammatory activity, analgesic property, and established safety record have also made NSAIDs an important tool for optimizing surgical outcomes. Non-ophthalmic formulations of bromfenac were...
Approved
Withdrawn
Matched Description: … Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. ... Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. …
Baclofen
Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients. Baclofen was reintroduced in 1971 as a treatment for spasticity and...
Approved
Matched Description: … Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. ... [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the …
Cephaloglycin
A cephalorsporin antibiotic that is no longer commonly used.
Approved
Matched Description: … A cephalorsporin antibiotic that is no longer commonly used. …
Lisocabtagene maraleucel
Lisocabtagene maraleucel is a chimeric antigen receptor (CAR) T-cell therapy, similar to brexucabtagene autoleucel and axicabtagene ciloleucel.[A228493,L31588] Lisocabtagene maraleucel is a genetically modified autologous T-cell therapy that targets CD19, the B-lymphocyte surface antigen B4. CAR T-cell therapy has changed the treatment of B-cell lymphomas, significantly increasing survival rates over standard...
Approved
Matched Description: … Lisocabtagene maraleucel is a chimeric antigen receptor (CAR) T-cell therapy, similar to [brexucabtagene ... [A228493,L31588] Lisocabtagene maraleucel is a genetically modified autologous T-cell therapy that targets ... majority of patients given lisocabtagene maraleucel reported an overall increase in quality of life over a …
Carbidopa
Carbidopa presents a chemical denomination of N-amino-alpha-methyl-3-hydroxy-L-tyrosine monohydrate. It potently inhibits aromatic amino acid decarboxylase (DDC) and due to its chemical properties, it does not cross the blood-brain barrier. Due to its activity, carbidopa is always administered concomitantly with levodopa. An individual formulation containing solely carbidopa was generated to treat...
Approved
Matched Description: … Carbidopa presents a chemical denomination of N-amino-alpha-methyl-3-hydroxy-L-tyrosine monohydrate. …
Sparfloxacin
Sparfloxacin is a fluoroquinolone antibiotic indicated for bacterial infections. Sparfloxacin exerts its antibacterial activity by inhibiting DNA gyrase, a bacterial topoisomerase. DNA gyrase is an essential enzyme which controls DNA topology and assists in DNA replication, repair, deactivation, and transcription.
Approved
Investigational
Withdrawn
Matched Description: … Sparfloxacin is a fluoroquinolone antibiotic indicated for bacterial infections. ... Sparfloxacin exerts its antibacterial activity by inhibiting DNA gyrase, a bacterial topoisomerase. …
Entecavir
Entecavir is an oral antiviral drug used in the treatment of hepatitis B infection. It is marketed under the trade name Baraclude (BMS).
Entecavir is a guanine analogue that inhibits all three steps in the viral replication process, and the manufacturer claims that it is more efficacious than previous agents...
Approved
Investigational
Matched Description: … Entecavir is a guanine analogue that inhibits all three steps in the viral replication process, and the …
Butalbital
Butalbital, or 5-allyl-5-isobutylbarbituric acid, is a derivative of barbituric acid which the hydrogens at position 5 are substituted by an allyl group and an isobutyl group. It is a short-to-intermediate acting member of barbiturates that exhibit muscle-relaxing and anti-anxiety properties that produce central nervous system (CNS) depression that ranges from...
Approved
Illicit
Matched Description: … [A177754] Butalbital has a low degree of selectivity and a narrow therapeutic index. ... Butalbital, or 5-allyl-5-isobutylbarbituric acid, is a derivative of barbituric acid which the hydrogens ... It is a short-to-intermediate acting member of barbiturates that exhibit muscle-relaxing and anti-anxiety …
Phenyl aminosalicylate
Approved
Ferric ammonium citrate
Approved
Experimental
Ambrosia trifida pollen
Ambrosia trifida pollen is the pollen of the Ambrosia trifida plant. Ambrosia trifida pollen is mainly used in allergenic testing.
Approved
Artemisia vulgaris root
Artemisia vulgaris root allergenic extract is used in allergenic testing.
Approved
Investigational
Glycine
A non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.
Approved
Nutraceutical
Vet approved
Matched Description: … A non-essential amino acid. ... It is also a fast inhibitory neurotransmitter. ... It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. …
Sumatriptan
Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches.[L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available in Europe in 1991 to treat migraines. Sumatriptan was granted FDA approval on 28 December 1992.
Approved
Investigational
Matched Description: … Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches …
Matched Categories: … Monoamine Oxidase A Substrates …
Matched Categories: … Monoamine Oxidase A Substrates …
Sucralfate
Sucralfate is a medication that is widely used to prevent and treat a number of diseases in the gastrointestinal tract such as duodenal ulcers [FDA label], gastro-esophageal reflux disease (GERD), gastritis, peptic ulcer disease, stress ulcer, in addition to dyspepsia . It is considered a cytoprotective agent, protecting cells in...
Approved
Matched Description: … Sucralfate is a medication that is widely used to prevent and treat a number of diseases in the gastrointestinal ... Sucralfate has been shown to be a well-tolerated and safe drug. ... It is considered a _cytoprotective agent_, protecting cells in the gastrointestinal tract from damage …
Teprotumumab
Teprotumumab is a fully human IgG1 monoclonal antibody directed against the human insulin-like growth factor-1 receptor. Following a clinical trial in which its efficacy in the treatment of thyroid eye disease (TED) was assessed, it received "breakthrough therapy" designation from the FDA in 2016 and was approved by the FDA...
Approved
Investigational
Matched Description: … Teprotumumab is a fully human IgG1 monoclonal antibody directed against the human insulin-like growth ... [L11359] Following a clinical trial in which its efficacy in the treatment of thyroid eye disease (TED ... [L11350] Thyroid eye disease is a potentially debilitating complication of Graves' Disease involving …
Mebendazole
A benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of microtubules. [PubChem]
Approved
Vet approved
Matched Description: … A benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of …
Hexaminolevulinate
Hexaminolevulinate is an optical imaging drug. In solution form it is instilled intravesically for use with photodynamic blue light cystoscopy as an adjunct to white light cystoscopy. On May 28, 2010, the U.S. Food and Drug Administration (FDA) granted approval for hexaminolevulinate hydrochloride (Cysview for Intravesical Solution, Photocure ASA), as...
Approved
Matched Description: … invasive papillary cancer of the bladder for patients suspected or known to have lesion(s) on the basis of a …
Nicoboxil
Nicoboxil has been investigated for the treatment of Acute Low Back Pain, where it is typically considered an effective and safe therapeutic option. Nevertheless, it is predominantly found paired with nonivamide as a combination topical analgesic product where its proposed mechanism of action as a rubefacient is complementary and ultimately...
Approved
Investigational
Matched Description: … where its proposed mechanism of action as a rubefacient is complementary and ultimately synergistic ... Nevertheless, it is predominantly found paired with nonivamide as a combination topical analgesic product …
Gonadorelin
Gonadorelin is another name for gonadotropin-releasing hormone (GnRH). It is a synthetic decapeptide prepared using solid phase peptide synthesis. GnRH is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pituitary.
Approved
Investigational
Vet approved
Matched Description: … It is a synthetic decapeptide prepared using solid phase peptide synthesis. …
Mycophenolate mofetil
Mycophenolate mofetil, also known as MMF or CellCept, is a prodrug of mycophenolic acid, and classified as a reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH). This drug is an immunosuppressant combined with drugs such as Cyclosporine and corticosteroids to prevent organ rejection after hepatic, renal, and cardiac transplants. It is...
Approved
Investigational
Matched Description: … as a reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH). ... Mycophenolate mofetil, also known as MMF or CellCept, is a prodrug of mycophenolic acid, and classified ... It demonstrates an increased bioavailability, a higher efficacy, and reduced gastrointestinal effects …
Vorinostat
Vorinostat (rINN) or suberoylanilide hydroxamic acid (SAHA), is a drug currently under investigation for the treatment of cutaneous T cell lymphoma (CTCL), a type of skin cancer, to be used when the disease persists, gets worse, or comes back during or after treatment with other medicines. It is the first...
Approved
Investigational
Matched Description: … It is the first in a new class of agents known as histone deacetylase inhibitors. ... Vorinostat (rINN) or suberoylanilide hydroxamic acid (SAHA), is a drug currently under investigation ... for the treatment of cutaneous T cell lymphoma (CTCL), a type of skin cancer, to be used when the disease …
Displaying drugs 3376 - 3400 of 11612 in total