Displaying drugs 3551 - 3575 of 11857 in total
Safflower oil
Safflower (Carthamus tinctorius L) is a herbaceous plant in the Asteraceae family. Extracted from the seeds of safflowers, safflower oil is a rich source of various saturated fatty acids, monounsaturated fatty acid (oleic acid) or essential n-6 polyunsaturated fatty acid (PUFA) linoleic acid [A32677, A32679], depending on the flower type....
Approved
Investigational
Matched Description: … Safflower (_Carthamus tinctorius_ L) is a herbaceous plant in the Asteraceae family. ... Extracted from the seeds of safflowers, safflower oil is a rich source of various saturated fatty acids ... Safflower oil with a higher content of polyunsaturated fatty acids is more commonly used as an edible …
Dapagliflozin
Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, and it was the first SLGT2 inhibitor to be approved. indicated for managing diabetes mellitus type 2. When combined with diet and exercise in adults, dapagliflozin helps to improve glycemic control by inhibiting glucose reabsorption in the proximal tubule of the nephron...
Approved
Matched Description: … Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, and it was the first SLGT2 inhibitor …
Lebrikizumab
Lebrikizumab is a monoclonal antibody against IL-13 that binds to a different epitope compared tralokinumab.[A262874,A262879]
On November 17, 2023, lebrikizumab was approved by the EMA under the brand name EBGLYSS for the treatment of moderate-to-severe atopic dermatitis in adult and adolescent patients 12 years and older with a body weight...
Approved
Investigational
Matched Description: … Lebrikizumab is a monoclonal antibody against IL-13 that binds to a different epitope compared [tralokinumab ... treatment of moderate-to-severe atopic dermatitis in adult and adolescent patients 12 years and older with a …
Propiverine
Propiverine is a widely used antimuscarinic drug with a mixed mode of action in the treatment of symptoms associated with overactive bladder (OAB) .
Overactive bladder (OAB) is a chronic condition of the lower urinary tract characterized by urinary urgency, increased frequency of urination, and nocturia (frequent waking during the...
Approved
Investigational
Matched Description: … Propiverine is a widely used antimuscarinic drug with a mixed mode of action in the treatment of symptoms ... OAB has a negative impact on quality of life and may lead to leakage and inconvenient urinary accidents ... Overactive bladder (OAB) is a chronic condition of the lower urinary tract characterized by urinary urgency …
Indapamide
The most significant modifiable risk factor for cardiovascular disease and the most prominent contributor to all-cause mortality is hypertension. Characterized by an office blood pressure of ≥140/90, hypertension is pervasive and impacts an estimated 25% of adults globally. Treatment for hypertension should include a number of lifestyle changes (ie. reduced...
Approved
Matched Description: … [A204134,A204161]
Indapamide is characterized by both a methylindoline and a sulfamoyl chlorobenzamide ... [A204155] Treatment for hypertension should include a number of lifestyle changes (ie. reduced sodium ... [A204155]
Thiazide-like diuretics such as indapamide are a valuable tool for the treatment of hypertension …
Albumin iodinated I-131 serum
Iodinated I-131 serum albumin is a radiopharmaceutical agent used for several diagnostic purposes, including the determination of body fluid volumes and the imaging of certain tissues.
Approved
Matched Description: … Iodinated I-131 serum albumin is a radiopharmaceutical agent used for several diagnostic purposes, including …
Albumin iodinated I-125 serum
I-125 iodinated albumin is a radiolabeled albumin-based diagnostic agent used in the determination of total blood and plasma volume.
Approved
Matched Description: … I-125 iodinated albumin is a radiolabeled albumin-based diagnostic agent used in the determination of …
Allogeneic processed thymus tissue
Allogeneic processed thymus tissue is used for immune reconstitution in immune disorders where the patients are severely immunocompromised due to the absence of a functional thymus, such as congenital athymia. As part of the immune system, the thymus is an organ responsible for the maturation and selection of T cells...
Approved
Matched Description: … [L38929] Congenital athymia is a rare condition that leads to the absence of a thymus at birth and a ... an organ responsible for the maturation and selection of T cells [A239814]; thus, patients without a ... reconstitution in immune disorders where the patients are severely immunocompromised due to the absence of a …
Tioguanine
An antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.
Approved
Acer negundo pollen
Acer negundo pollen is the pollen of the Acer negundo plant. Acer negundo pollen is mainly used in allergenic testing.
Approved
Quercus alba pollen
Quercus alba pollen, or oak white pollen, is a non-standardized allergen extract used for the diagnosis and treatment of allergic disease to grass pollen. It can be subcutaneously administered to initiate an immune response in case of an allergic reaction. Diagnostic allergenic extracts are primarily indicated for establishing clinical relevance...
Approved
Matched Description: … Quercus alba pollen, or oak white pollen, is a non-standardized allergen extract used for the diagnosis …
Amitriptylinoxide
Amitriptylinoxide has been used in trials studying Major Depression.
Approved
Investigational
Palonosetron
Palonosetron (INN, trade name Aloxi) is an antagonist of 5-HT3 receptors that is indicated for the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). It is the most effective of the 5-HT3 antagonists in controlling delayed CINV nausea and vomiting that appear more than 24 hours after the first...
Approved
Investigational
Matched Description: … controlling delayed CINV nausea and vomiting that appear more than 24 hours after the first dose of a …
Isosorbide
Isosorbide was previously available in an oral formulation for the reduction of intraocular pressure. It was approved by the FDA in 1980, but has since been discontinued. Currently, isosorbide is an organic nitrate currently available in the isosorbide mononitrate and isosorbide dinitrate forms, and is used for the prevention of...
Approved
Investigational
Diethylcarbamazine
An anthelmintic used primarily as the citrate in the treatment of filariasis, particularly infestations with Wucheria bancrofti or Loa loa.
Approved
Investigational
Vet approved
Brown iron oxide
Approved
Experimental
Escitalopram
Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic citalopram. It is used to restore serotonergic function in the treatment of depression and anxiety.[L8513,L8516,L8522] Escitalopram is approximately 150 times more potent than citalopram’s R-enantiomer and is responsible for the vast majority of citalopram’s clinical activity, with...
Approved
Matched Description: … Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic [citalopram …
Matched Categories: … Monoamine Oxidase A Substrates …
Matched Categories: … Monoamine Oxidase A Substrates …
Edetate disodium anhydrous
Edetate disodium anhydrous is a polyvalent chelating agent used to treat hypercalcemia and digitalis toxicity associated ventricular arrhythmias.
Approved
Vet approved
Matched Description: … Edetate disodium anhydrous is a polyvalent chelating agent used to treat hypercalcemia and digitalis …
Pyrophosphoric acid
Approved
Experimental
Spectinomycin
An antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea.
Approved
Investigational
Vet approved
Inotuzumab ozogamicin
Inotuzumab ozogamicin is an antibody-drug conjugate consisting of a humanized IgG4 kappa CD22-targeting monoclonal antibody covalently attached to calicheamicin derivative, N-acetyl-gamma-calicheamicin dimethylhydrazide. The antibody portion of the drug binds to CD22 receptors expressed on leukemic B cells and intracellularly releases N-acetyl-gamma-calicheamicin dimethylhydrazide, which produces cytotoxic effects. Inotuzumab ozogamicin was first...
Approved
Investigational
Matched Description: … [L938] A month later, inotuzumab ozogamicin was also approved by the FDA.[L50542] ... Inotuzumab ozogamicin is an antibody-drug conjugate consisting of a humanized IgG4 kappa CD22-targeting …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index …
Rasagiline
Rasagiline is an irreversible inhibitor of monoamine oxidase and is used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases.
Approved
Matched Description: … Rasagiline is an irreversible inhibitor of monoamine oxidase and is used as a monotherapy in early Parkinson's …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Elivaldogene autotemcel
Elivaldogene autotemcel is a gene therapy consisting of genetically modified autologous cells. It is used to provide functional copies of human adrenoleukodystrophy protein (ALDP) in patients with adrenoleukodystrophy, an X-linked genetic disorder characterized by missing or non-functional ABCD1 gene that codes for ALDP. ALDP is a key protein that normally...
Approved
Matched Description: … Elivaldogene autotemcel is a gene therapy consisting of genetically modified autologous cells. ... [A243691] ALDP is a key protein that normally breaks down fatty substances in the body called very long-chain ... Gene therapy with autologous hematopoietic stem cells was introduced and investigated as a possible treatment …
Tolmetin
A non-steroidal anti-inflammatory agent (anti-inflammatory agents, NON-steroidal) similar in mode of action to indomethacin.
Approved
Matched Description: … A non-steroidal anti-inflammatory agent (anti-inflammatory agents, NON-steroidal) similar in mode of …
Potassium aspartate
Approved
Experimental
Displaying drugs 3551 - 3575 of 11857 in total