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Displaying drugs 476 - 500 of 15298 in total
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Christchurch/16/2010 NIB-74XP (H1N1) hemagglutinin antigen (formaldehyde inactivated …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Guangdong-Maonan/SWL1536/2019 CNIC-1909 (H1N1) antigen (UV, formaldehyde inactivated …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. …
Glutethimide is a hypnotic and sedative. Its use has been largely superseded by other drugs.
Approved
Illicit
Matched Synonyms: … 2-Ethyl-2-phenylglutarimide …
Matched Iupac: … 3-ethyl-3-phenylpiperidine-2,6-dione …
Matched Description: … Glutethimide is a hypnotic and sedative. Its use has been largely superseded by other drugs. …
Lasofoxifene is a non-steroidal 3rd generation selective estrogen receptor modulator (SERM) that selectively binds to both ERα and ERβ with high affinity. It is a naphthalene derivative marketed for prevention and treatment of osteoporosis and for the treatment of vaginal atrophy. It was initially developed as Oporia by Pfizer as...
Approved
Investigational
Matched Synonyms: … (-)-cis-5,6,7,8-Tetrahydro-6-phenyl-5-(p-(2-(1-pyrrolidinyl)ethoxy)phenyl)-2-naphthol …
Matched Iupac: … (5R,6S)-6-phenyl-5-{4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}-5,6,7,8-tetrahydronaphthalen-2-ol …
Matched Description: … atrophy, in which were both rejected for approval by FDA. ... with a newly submitted New Drug Application in 2008. ... It is a naphthalene derivative marketed for prevention and treatment of osteoporosis and for the treatment …
Avelumab is a human IgG1 lambda monoclonal antibody that binds programmed cell death ligand-1 (PD-L1) to block its interaction with its receptors found on T cells and antigen-presenting cells. Avelumab was first approved by the FDA on March 23, 2017. On September 18 and December 18 of the same year,...
Approved
Investigational
Matched Description: … Avelumab is a human IgG1 lambda monoclonal antibody that binds programmed cell death ligand-1 (PD-L1) ... It is used in the treatment of Merkel cell carcinoma, metastatic urothelial carcinoma, or renal cell …
Matched Products: … BAVENCIO CONCENTRATE FOR SOLUTION FOR INFUSION 200MG/10ML …
Canis lupus familiaris dander is the dander of Canis lupus familiaris. Canis lupus familiaris dander is used in allergenic testing.
Approved
Matched Description: … Canis lupus familiaris dander is used in allergenic testing. …
Corticorelin, available commercially as corticorelin ovine triflutate (tradename Acthrel), is a synthetic form of the peptide human corticotropin-releasing hormone (hCRH), a potent stimulator of adrenocorticotropic hormone (ACTH) release from the anterior pituitary. Endogenous forms hCRH are involved in the stress response and its main function is stimulation of the pituitary...
Approved
Matched Description: … It provides a differential diagnosis for Cushing's disease (a pituitary source of ACTH excess) or of ... It is used as a diagnostic agent to evaluate the status of the pituitary-adrenal axis in the differentiation ... Endogenous forms hCRH are involved in the stress response and its main function is stimulation of the …
Matched Categories: … Tests for Pituitary Function …
Retinal vascular diseases (RVDs) such as diabetic macular edema (DME), age-related macular degeneration (AMD), and retinal vein occlusion (RVO) are typically caused by retinal ischemia and subsequent neovascularization (NV).[A225985, A225990, A225995] Vascular endothelial growth factor A (VEGF-A) is a well-known mediator of retinal NV, and many currently approved RVD therapies...
Approved
Investigational
Matched Description: … soluble ligands Ang-1 and Ang-2, has been shown to play critical roles in mediating VEGF-A-induced NV ... [L40026] It received subsequent approval for the same indications in Canada in May 2022. ... [L42305] In July 2022, the EMA's Committee for Medicinal Products for Human Use (CHMP) recommended faricimab …
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19), which is a respiratory disease that is capable of progressing to viral pneumonia and acute respiratory distress syndrome (ARDS); COVID-19 can be fatal. Like other RNA viruses, SARS-CoV-2 depends on an RNA-dependent RNA polymerase...
Approved
Investigational
Matched Iupac: … 2-ethylbutyl (2S)-2-{[(S)-{[(2R,3S,4R,5R)-5-{4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl}-5-cyano-3,4-dihydroxyoxolan ... -2-yl]methoxy}(phenoxy)phosphoryl]amino}propanoate …
Matched Description: … in 2016 as a potential treatment for Ebola. ... ] leading to considerable interest in remdesivir as a possible treatment for COVID-19. ... the treatment of COVID-19 on October 22, 2020. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antivirals for Systemic Use ... Antiinfectives for Systemic Use ... SARS-CoV-2 Nucleotide Analog RNA Polymerase Inhibitor ... Approved Treatments for COVID-19 …
Matched Products: … COVIFOR (REMDESIVIR FOR INJECTION 100MG/VIAL) ... VEKLURY® LYOPHILIZED POWDER FOR IV INFUSION 100MG/VIAL …
Thyrotropin alfa is a recombinant form of thyroid stimulating hormone used in performing certain tests in patients who have or have had thyroid cancer. It is also used along with a radioactive agent to destroy remaining thyroid tissue in certain patients who have had their thyroid gland removed because of...
Approved
Vet approved
Matched Description: … Thyrotropin alfa is a recombinant form of thyroid stimulating hormone used in performing certain tests ... It is also used along with a radioactive agent to destroy remaining thyroid tissue in certain patients ... The alpha subunit of thyrotropin alfa, which is the effector region responsible for the stimulation of …
Matched Products: … Thyrogen 0.9 mg Powder for Solution for Injection ... THYROGEN 0,9 MG/1,08 ML IM ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ İÇEREN FLAKON, 2 FLAKON …
Recombinant human chorionic gonadotropin with 2 subunits, alpha = 92 residues, beta = 145 residues, each with N-and O-linked carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN-13, ASN-30, SER-121, SER-127, SER-132 and SER-138 (on beta subunit). The primary structure of the alpha-chain of r-hCG is identical...
Approved
Matched Description: … Recombinant human chorionic gonadotropin with 2 subunits, alpha = 92 residues, beta = 145 residues, each …
Matched Products: … Ovidrel Solution for Injection 250 mcg ... OVIDREL 250MCG/0.5ML SOLUTION FOR INJECTION …
Field mushroom allergenic extract is used in allergenic testing.
Approved
Matched Description: … Field mushroom allergenic extract is used in allergenic testing. …
Levomilnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI), although it is a more potent inhibitor of norepinephrine reuptake than serotonin reuptake.[A261181, A38560] Levomilnacipran is the more active 1S,2R-enantiomer in the racemate milnacipran.[A261181, L47956] Once administered, interconversion between levomilnacipran and its stereoisomer does not occur in humans. First approved...
Approved
Investigational
Matched Synonyms: … CYCLOPROPANECARBOXAMIDE, 2-(AMINOMETHYL)-N,N-DIETHYL-1-PHENYL-, (1S,2R)- …
Matched Iupac: … (1S,2R)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclopropane-1-carboxamide …
Matched Description: … [L47956] While levomilnacipran was previously investigated and proposed as a potential treatment for ... a more potent inhibitor of norepinephrine reuptake than serotonin reuptake. ... stroke in Europe, the EMA decided against this use. …
Matched Categories: … Antidepressive Agents Indicated for Depression …
Sotalol is a methanesulfonanilide developed in 1960. It was the first of the class III anti arrhythmic drugs. Sotalol was first approved as an oral tablet on 30 October 1992. A racemic mixture of sotalol is currently formulated as a tablet, oral solution, and intravenous injection indicated for life threatening...
Approved
Matched Synonyms: … 4'-(1-hydroxy-2-(isopropylamino)ethyl)methane sulfonanilide …
Matched Iupac: … N-(4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}phenyl)methanesulfonamide …
Matched Description: … Sotalol is a methanesulfonanilide developed in 1960. ... in atrial fibrillation or flutter. ... injection indicated for life threatening ventricular arrhythmias and maintaining normal sinus rhythm …
Matched Categories: … Medications that reduce magnesium levels ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index …
Muskmelon allergenic extract is used in allergenic testing.
Approved
Matched Description: … Muskmelon allergenic extract is used in allergenic testing. …
Human Beta-glucocerebrosidase or Beta-D-glucosyl-N-acylsphingosine glucohydrolase E.C. 3.2.1.45. 497 residue protein with N-linked carbohydrates, MW=59.3 kD. Alglucerase is prepared by modification of the oligosaccharide chains of human Beta-glucocerebrosidase. The modification alters the sugar residues at the non-reducing ends of the oligosaccharide chains of the glycoprotein so that they are predominantly terminated...
Approved
Matched Products: … (Imiglucerase) 400U Powder for solution for injection …
Potassium is an essential nutrient, like Calcium and Magnesium. It was identified as a shortfall nutrient by the 2015-2020 Advisory Committee of Dietary Guidelines for Americans. Many conditions and diseases interfere with normal body potassium balance, and underconsumption of potassium is one example. Hypokalemia (low potassium) or hyperkalemia (high potassium)...
Approved
Experimental
Matched Description: … Potassium is often a key ingredient for intravenous fluids, given to patients in clinical settings for ... It was identified as a shortfall nutrient by the 2015-2020 Advisory Committee of Dietary Guidelines for ... They are available in an assortment of tablet, injection, and other forms, depending on the setting and …
Matched Mixtures name: … Swical-energy 3e Age ... BION 3 FILM COATED TABLET ... Formula F L W …
Matched Products: … Port A Mins Super Potassium 99 …
Velaglucerase alfa is a gene-activated human recombinant glucocerebrosidase used for the treatment of Type 1 Gaucher disease, caused by a deficiency of the lysosomal enzyme glucocerebrosidase. Additionally, Velaglucerase alfa has also been investigated for use in Type 3 Gaucher disease.
Approved
Investigational
Matched Description: … Additionally, Velaglucerase alfa has also been investigated for use in Type 3 Gaucher disease. ... Velaglucerase alfa is a gene-activated human recombinant glucocerebrosidase used for the treatment of ... Type 1 Gaucher disease, caused by a deficiency of the lysosomal enzyme glucocerebrosidase. …
Matched Products: … VPRIV POWDER FOR SOLUTION FOR INFUSION 400 UNITS/VIAL …
Esculin is found in barley. Vitamin C2 is generally considered a bioflavanoid, related to vitamin P esculin is a glucoside that naturally occurs in the horse chestnut (Aesculus hippocastanum), California Buckeye (Aesculus californica) and in daphnin (the dark green resin of Daphne mezereum). Esculin belongs to the family of Glycosyl...
Approved
Matched Synonyms: … 6-(beta-D-Glucopyranosyloxy)-7-hydroxy-2H-1-benzopyran-2-one …
Matched Iupac: … 7-hydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2H-chromen-2-one …
Matched Description: … group via a C-, S-,N-,O-, or Se- glycosidic bond. ... These are carbohydrate derivatives in which a sugar group is bonded through its anmoeric carbonA to another ... Esculin is found in barley. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Fosaprepitant is an intravenously administered antiemetic drug. It is a prodrug of Aprepitant. It aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment.
Approved
Matched Iupac: … (3-{[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl …
Matched Description: … It is a prodrug of Aprepitant. ... It aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment …
Matched Products: … Powder for Solution for Infusion 150mg ... APRITANT IV® 150 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. …
Chlorpropamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. Sulfonylureas increase both basal insulin secretion and meal-stimulated insulin release. Medications in this class...
Approved
Investigational
Matched Synonyms: … 1-(p-chlorobenzenesulfonyl)-3-propylurea ... 1-(p-chlorophenylsulfonyl)-3-propylurea ... 1-propyl-3-(p-chlorobenzenesulfonyl)urea …
Matched Iupac: … 1-(4-chlorobenzenesulfonyl)-3-propylurea …
Matched Description: … Chlorpropamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes ... Chlorpropamide is not recommended for the treatment of NIDDM as it increases blood pressure and the risk ... Medications in this class differ in their dose, rate of absorption, duration of action, route of elimination …
Matched Categories: … Drugs Used in Diabetes …
Poliovirus type 1 antigen is a suspension of poliovirus Type 1 (Mahoney) used in the active immunization of infants (as young as 6 weeks of age), children, and adults for the prevention of poliomyelitis caused by poliovirus Type 1. The vaccine contains purified and inactivated poliovirus type 1 that were...
Approved
Investigational
Matched Description: … Poliovirus type 1 antigen is a suspension of poliovirus Type 1 (Mahoney) used in the active immunization ... of infants (as young as 6 weeks of age), children, and adults for the prevention of poliomyelitis caused ... The vaccine contains purified and inactivated poliovirus type 1 that were grown from a continuous line …
Matched Mixtures name: … -POLIO SUSPENSION FOR INJECTION IN PRE-FILLED SYRINGE ... Hexaxim Suspension for Injection ... BOOSTRIX POLIO SUSPENSION FOR INJECTION …
Eculizumab is a monoclonal antibody that targets complement protein C5.[L6919,A2245] Binding to this protein prevents the activation of a complement terminal complex, which is used to treat a number of autoimmune conditions.[L6919,A2245,A2246] Eculizumab was granted FDA approval on 16 March 2007. In Q1 2023, the EMA's Committee for Medicinal Products...
Approved
Investigational
Matched Description: … [L6919] In Q1 2023, the EMA's Committee for Medicinal Products for Human Use (CHMP) adopted a positive ... is used to treat a number of autoimmune conditions. ... Eculizumab is a monoclonal antibody that targets complement protein C5. …
Matched Products: … Soliris Concentrate for Solution for Infusion 300mg/vial …
Doripenem is a broad-spectrum, carbapenem antibiotic marketed under the brand name Doribax by Janssen. Doripenem injection was approved by the FDA in 2007 to treat complicated urinary tract and intra-abdominal infections. In a clinical trial of doripenem treatment in ventilator associated pneumonia (vs. imipenem and cilastatin), it was found that...
Approved
Investigational
Matched Iupac: … yl]sulfanyl}-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid ... (4R,5S,6S)-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-3-{[(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3- …
Matched Description: … The FDA revised the doripenem label in 2014 to include a warning against use in ventilator-associated ... In a clinical trial of doripenem treatment in ventilator associated pneumonia (vs. imipenem and cilastatin ... pneumonia and to reiterate its safety and efficacy for its approved indications. …
Matched Salts cas: … 364622-82-2
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … Powder for Injection 500mg ... DORIBAX 500 MG (Doripenem) for Injection …
Displaying drugs 476 - 500 of 15298 in total