Displaying drugs 876 - 900 of 14030 in total
Equine Botulinum Neurotoxin E Immune FAB2
Equine Botulinum Neurotoxin E Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype E. It is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes E in...
Approved
Experimental
Investigational
Matched Description: … exposure to botulinum neurotoxin serotypes E in adults and pediatric patients. ... Equine Botulinum Neurotoxin E Immune FAB2 is composed of a mixture of immune globulin fragments purified ... It is intravenously administered for the treatment of symptomatic botulism following documented or suspected …
Equine Botulinum Neurotoxin C Immune FAB2
Equine Botulinum Neurotoxin C Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype C. It is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes C in...
Approved
Experimental
Investigational
Matched Description: … exposure to botulinum neurotoxin serotypes C in adults and pediatric patients. ... Equine Botulinum Neurotoxin C Immune FAB2 is composed of a mixture of immune globulin fragments purified ... It is intravenously administered for the treatment of symptomatic botulism following documented or suspected …
Methacholine
Asthma is a complex condition associated with phenomena such as airway hyperresponsiveness (AHR), in which the smooth muscle in the airways (ASM) excessively contracts in response to stimuli, reducing pulmonary function and causing symptoms such as difficulty breathing.[A229598, A229603] Although the underlying pathology of AHR is complex, ASM contraction can...
Approved
Investigational
Matched Description: … Asthma is a complex condition associated with phenomena such as airway hyperresponsiveness (AHR), in ... [L31763] In patients with AHR, a lower dose of methacholine is required to induce bronchoconstriction ... , which forms the basis for the methacholine challenge test to diagnose AHR. …
Metreleptin
Metreleptin, a recombinant analog of the human hormone leptin, is an orphan drug used to treat complications of leptin deficiency in people with lipodystrophy. Lipodystrophies include a range of disorders characterized by the reduction, absence, or altered distribution of adipose tissue. Complications of lipodystrophy include metabolic abnormalities such as hypertriglyceridemia,...
Approved
Matched Description: … [L41315] Metreleptin was approved by Health Canada in January 2024 for the same patient population, in ... [L41315]
In February 2014, metreleptin was approved by the FDA for the treatment of complications ... Metreleptin is produced in _E. coli_ and differs from native human leptin by the addition of a methionine …
Safinamide
Safinamide is for the treatment of parkinson's disease. It was approved in Europe in February 2015, and in the United States on March 21, 2017.
Approved
Investigational
Matched Description: … Safinamide is for the treatment of parkinson's disease. ... It was approved in Europe in February 2015, and in the United States on March 21, 2017. …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Ethchlorvynol
Ethchlorvynol is a sedative and hypnotic drug. It has been used to treat insomnia, but has been largely superseded and is only offered where an intolerance or allergy to other drugs exists.
Approved
Illicit
Withdrawn
Matched Description: … Ethchlorvynol is a sedative and hypnotic drug. …
Nomifensine
Nomifensine, formerly marketed as Merital capsules, was associated with an increased incidence of hemolytic anemia. The approved application holder removed Merital capsules from the market on January 23, 1986. FDA published a notice of its determination that Merital capsules were removed from the market for safety reasons (see the Federal...
Approved
Withdrawn
Matched Description: … FDA published a notice of its determination that Merital capsules were removed from the market for safety ... Approval of the NDA for Merital capsules was withdrawn on March 20, 1992 (see the Federal Register of …
Relebactam
Relebactam is a diazabicyclooctane beta-lactamase inhibitor, similar in structure to avibactam.[A181195,A181207] It includes a piperidine ring which reduces export from bacterial cells by producing a positive charge. It is currently available in a combination product which includes imipenem and cilastatin to treat complicated urinary tract infections (UTIs), pyelonephritis, and complicated...
Approved
Investigational
Matched Description: … Relebactam is a diazabicyclooctane beta-lactamase inhibitor, similar in structure to [avibactam]. ... [A181207] It is currently available in a combination product which includes [imipenem] and [cilastatin ... product RecarbrioⓇ in July 2019. …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Magaldrate
Magaldrate is an antacid drug used for the treatment of esophagitis, duodenal and gastric ulcers, and gastroesophageal reflux. Magaldrate has been discontinued in the US market.
Approved
Withdrawn
Matched Description: … Magaldrate has been discontinued in the US market. ... Magaldrate is an antacid drug used for the treatment of esophagitis, duodenal and gastric ulcers, and …
Matched Categories: … Drugs for Acid Related Disorders …
Matched Categories: … Drugs for Acid Related Disorders …
Human papillomavirus type 11 L1 capsid protein antigen
Human papillomavirus type 11 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus...
Approved
Matched Description: … Human papillomavirus type 11 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human ... It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused ... major capsid (L1) protein of HPV Types 6, 11, 16, and 18, which are produced by separate fermentations in …
Matched Mixtures name: … GARDASIL 9 SUSPENSION FOR INJECTION ... GARDASIL SUSPENSION FOR INJECTION …
Matched Mixtures name: … GARDASIL 9 SUSPENSION FOR INJECTION ... GARDASIL SUSPENSION FOR INJECTION …
Pentostatin
A potent inhibitor of adenosine deaminase. The drug is effective in the treatment of many lymphoproliferative malignancies, particularly hairy-cell leukemia. It is also synergistic with some other antineoplastic agents and has immunosuppressive activity.
Approved
Investigational
Matched Description: … A potent inhibitor of adenosine deaminase. ... The drug is effective in the treatment of many lymphoproliferative malignancies, particularly hairy-cell …
Matched Categories: … Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …
Matched Categories: … Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …
Defibrotide
Defibrotide is the sodium salt of a mixture of single-stranded oligodeoxyribonucleotides derived from porcine mucosal DNA. It has been shown to have antithrombotic, anti-inflammatory and anti-ischemic properties (but without associated significant systemic anticoagulant effects). It is marketed under the brand names Dasovas (FM), Noravid, and Prociclide in a variety of...
Approved
Investigational
Matched Description: … It is marketed under the brand names Dasovas (FM), Noravid, and Prociclide in a variety of countries. ... In the USA it is was approved in March, 2016 as Defitelio. ... Defibrotide is the sodium salt of a mixture of single-stranded oligodeoxyribonucleotides derived from …
Influenza B virus B/Phuket/3073/2013 live (attenuated) antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from …
Influenza B virus B/Brisbane/60/2008 live (attenuated) antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from …
Corynebacterium diphtheriae
Corynebacterium diphtheriae toxin is extracted from the pathogenic actinobacterium C. diphtheriae that causes diphtheria. The bacteria culture is grown in a medium and through purification, diphtheria toxin is detoxified with formaldehyde and diafiltered. The vaccine is intramuscularly administered to provide active immunization against diphtheria in infants and children.
Approved
Investigational
Matched Description: … The bacteria culture is grown in a medium and through purification, diphtheria toxin is detoxified with ... The vaccine is intramuscularly administered to provide active immunization against diphtheria in infants …
Matched Mixtures name: … PREVENAR 13 SUSPENSION FOR INJECTION ... Boostrix Injektionssuspension in einer Fertigspritze ... Boostrix Polio - Injektionssuspension in einer Fertigspritze …
Matched Mixtures name: … PREVENAR 13 SUSPENSION FOR INJECTION ... Boostrix Injektionssuspension in einer Fertigspritze ... Boostrix Polio - Injektionssuspension in einer Fertigspritze …
Aureobasidium pullulans var. pullutans
Aureobasidium pullulans var. pullutans is a fungus which can provoke allergic reactions. Aureobasidium pullulans var. pullutans extract is used in allergenic testing.
Approved
Matched Description: … Aureobasidium pullulans var. pullutans extract is used in allergenic testing. ... Aureobasidium pullulans var. pullutans is a fungus which can provoke allergic reactions. …
Matched Mixtures name: … A Mold Mixture ... A Mold Mixture ... A Mold Mixture …
Matched Mixtures name: … A Mold Mixture ... A Mold Mixture ... A Mold Mixture …
Mestranol
The 3-methyl ether of ethinyl estradiol. It must be demethylated to be biologically active. It is used as the estrogen component of many combination ORAL contraceptives.
Approved
Matched Iupac: … 3aS,3bR,9bS,11aS)-1-ethynyl-7-methoxy-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Categories: … Hormonal Contraceptives for Systemic Use …
Matched Categories: … Hormonal Contraceptives for Systemic Use …
Technetium Tc-99m pertechnetate
Technetium Tc-99m pertechnetate is a radiopharmaceutical diagnostic agent composed of an oxoanion with the chemical formula TcO4-. Pertechnetate has a wide variety of uses within nuclear medicine as it distributes within the body to a similar extent as iodine. It also concentrates in the thyroid gland, salivary glands, gastric mucosa,...
Approved
Investigational
Matched Description: … This is normally supplied in a hospital setting through the use of a technetium-99m generator, whereby ... promptly used for clinical diagnostics. ... a similar extent as iodine. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Creatine
An amino acid derivative that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as creatinine in the urine.
Approved
Investigational
Nutraceutical
Matched Description: … An amino acid derivative that occurs in vertebrate tissues and in urine. ... Creatine is excreted as creatinine in the urine. ... In muscle tissue, creatine generally occurs as phosphocreatine. …
Atriplex polycarpa pollen
Atriplex polycarpa pollen is the pollen of the Atriplex polycarpa plant. Atriplex polycarpa pollen is mainly used in allergenic testing.
Approved
Matched Description: … Atriplex polycarpa pollen is mainly used in allergenic testing. …
Clomifene
A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue.
Approved
Investigational
Matched Description: … A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the …
Trimipramine
Tricyclic antidepressant similar to imipramine, but with more antihistaminic and sedative properties.
Approved
Matched Categories: … Antidepressive Agents Indicated for Depression ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index …
Sodium iodide
Sodium iodide is a water-soluble ionic compound with a crystal lattice. Sodium iodide is a source of iodine and can be administered as a supplement for total parenteral nutrition but is more commonly used in veterinary medicine. Radiolabelled compound, DB09293, is used as a diagnostic tool to evaluate thyroid function...
Approved
Matched Description: … Sodium iodide is a source of iodine and can be administered as a supplement for total parenteral nutrition ... [L2065] but is more commonly used in veterinary medicine. ... Sodium iodide is a water-soluble ionic compound with a crystal lattice. …
Crotalus adamanteus antivenin
Each year it is estimated there are 45,000 snakebites in the US and 300,000 to 400,000 bites worldwide. About 8000 of these snakebites involve venomous snake species. The majority of people bitten are males and about 50% occur in the age group of 18 to 28 .
The eastern diamondback...
Approved
Experimental
Matched Description: … Each year it is estimated there are 45,000 snakebites in the US and 300,000 to 400,000 bites worldwide ... The majority of people bitten are males and about 50% occur in the age group of 18 to 28 [F116]. …
Displaying drugs 876 - 900 of 14030 in total