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Displaying drugs 226 - 250 of 4669 in total
Investigational
Matched Synonyms: … Dna (synthetic human adenovirus 5/35 vector load703 human cd137 ligand and trimerized membrane-bound …
Investigational
Matched Synonyms: … interfering RNA (siRNA) therapeutic directed against transforming growth factor-beta 1 (TGF-beta 1) and
PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) designed to down-regulate the expression of EVI1 oncogene in cancer cells.
Investigational
Matched Synonyms: … Nanocomplex consisting of a small interfering RNA that targets the human EV11 oncogenic transcription factor and
Matched Description: … PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) …
Tolnaftate is a synthetic over-the-counter anti-fungal agent. It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot and ringworm. It is sold under several brand names, most notably Tinactin and Odor Eaters.
Approved
Investigational
Vet approved
Matched Synonyms: … Methyl (3-methylphenyl)carbamothioic acid O-2-naphthalenyl ester ... m,N-Dimethylthiocarbanilic acid O-2-naphthyl ester ... 2-Naphthyl N-methyl-N-(3-tolyl)thionocarbamate …
Matched Iupac: … N-methyl-N-(3-methylphenyl)-1-(naphthalen-2-yloxy)methanethioamide …
Matched Description: … and ringworm. ... It is sold under several brand names, most notably Tinactin and Odor Eaters. ... It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot …
Matched Mixtures name: … Terbinafine HCl Chlortimazole and Tolnaftate …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids
Matched Products: … Up and Up Antifungal ... Up and Up Soothing Antifungal ... Fungi Nail Toe and Foot …
Zenocutuzumab is under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy in HER2+ and With Endocrine Therapy in ER+ and Low HER2 Breast Cancer).
Investigational
Matched Synonyms: … Immunoglobulin g1, bispecific, anti-(human epidermal growth factor receptors, her2 and her3) (humanized ... antibody with enhanced antibody-dependent cell-mediated cytotoxicity (adcc) activity targeting her2 and
Matched Description: … With Endocrine Therapy in ER+ and Low HER2 Breast Cancer). ... under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy in HER2+ and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Oxymetazoline is an imidazole derivative and a potent, direct-acting alpha (α)-adrenergic agonist with affinity to both α1- and α2-adrenoceptors. Oxymetazoline is available in various formulations with a wide variety of clinical implications. The topical formulation of the drug is used to treat persistent facial redness in adults. As an effective...
Approved
Investigational
Matched Synonyms: … 2-(4-tert-butyl-2,6-dimethyl-3-hydroxybenzyl)-2-imidazoline ... 6-t-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol ... 6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol …
Matched Iupac: … 6-tert-butyl-3-[(4,5-dihydro-1H-imidazol-2-yl)methyl]-2,4-dimethylphenol …
Matched Description: … affinity to both α1- and α2-adrenoceptors. ... Oxymetazoline is an imidazole derivative and a potent, direct-acting alpha (α)-adrenergic agonist with ... is used for regional anesthesia during dental procedures in children and adults. …
Matched Mixtures name: … Mucinex Sinus-Max Pressure, Pain and Cough and Mucinex Sinus-Max Severe Congestion Relief Clear and Cool …
Matched Salts name: … Oxymetazoline hydrochloride
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Up and Up nasal ... Up and up nasal ... Breaze Nasal Sinus Colds and Allergies …
Triptorelin is a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion. After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production and testicular and ovarian steroidogenesis. Serum testosterone concentrations may fall to levels...
Approved
Vet approved
Matched Iupac: … 1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-3-(1H-indol-3-yl)propanamido]- ... hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol-4-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-( ... carbamimidamido-1-[(2S)-2-[(carbamoylmethyl)carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]-2-[(2R)-2-[(2S)-2-[(2S)-3- …
Matched Description: … and testicular and ovarian steroidogenesis. ... After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production …
Matched Salts cas: … 124508-66-3
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Hormones and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION 11.25 mg/vial ... POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION 3.75 mg/vial …
Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for prescription use in 1976 and then for over-the-counter (OTC) use in 1994. It can effectively manage acute pain as well as pain related to rheumatic diseases, and has a well studied adverse effect profile. Given its...
Approved
Vet approved
Matched Synonyms: … (+)-2-(6-Methoxy-2-naphthyl)propionic acid ... (+)-2-(Methoxy-2-naphthyl)-propionic acid ... (S)-2-(6-Methoxy-2-naphthyl)propanoic acid
Matched Iupac: … (2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid
Matched Description: … prescription use in 1976 and then for over-the-counter (OTC) use in 1994. ... Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for ... [A178975] It can effectively manage acute pain as well as pain related to rheumatic diseases, and has …
Matched Salts cas: … 26159-34-2 …
Matched Mixtures name: … Naproxen Sodium and Diphenhydramine Hydrochloride ... Naproxen Sodium and Pseudoephedrine Hydrochloride Sinus and Cold ... Naproxen Sodium and Pseudoephedrine Hydrochloride Sinus and Headache …
Matched Categories: … Naphthaleneacetic Acids ... Arylpropionic acid NSAIDS ... Antiinflammatory and Antirheumatic Products ... naproxen and misoprostol ... naproxen and esomeprazole …
Matched Products: … NAPROXEN ACIS 500MG ... Up and Up Naproxen sodium ... Back and Muscle Pain …
Investigational
Matched Synonyms: … engager antibody with a single chain fc moiety that binds to b cell maturation antigen surface receptor and
Lansoprazole marketed under the brand Prevacid, is a proton pump inhibitor (PPI) and is structurally classified as a substituted benzimidazole. It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective at promoting healing in ulcerative diseases, and treating gastroesophageal reflux disease (GERD) along with other pathologies...
Approved
Investigational
Matched Iupac: … 2-{[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methanesulfinyl}-1H-1,3-benzodiazole …
Matched Description: … [A177065] It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective ... with other pathologies caused by excessive acid secretion. ... Lansoprazole marketed under the brand Prevacid, is a proton pump inhibitor (PPI) and is structurally …
Matched Mixtures name: … Lansoprazole, Amoxicillin, and Clarithromycin ... Lansoprazole, Amoxicillin and Clarithromycin ... Lansoprazole, Amoxicillin and Clarithromycin …
Matched Categories: … Acid Reducers ... Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders ... Inhibition Gastric Acid Secretion ... Alimentary Tract and Metabolism …
Matched Products: … Foster and Thrive Acid Reducer ... Smart Sense Acid Reducer ... CareOne Acid Reducer …
Investigational
Matched Synonyms: … Flt3 ligand, IL-7, IL-15 and IL-2 to generate the NK cell ... The cells are expanded and differentiated in the presence of cytokines including thrombopoietin, SCF, …
Omega-6 fatty acids are polyunsaturated fatty acids with a final carbon-carbon double bond in the n-6 position, that is, the sixth bond, counting from the methyl end. They are a family of fatty acid molecules that act as precursors to potent lipid mediator signalling molecules with either pro-inflammatory and anti-inflammatory...
Nutraceutical
Matched Synonyms: … Omega 6 fatty acids ... Omega 6 acids ... n-6 fatty acids
Matched Name: … Omega-6 fatty acids
Matched Description: … Omega-6 fatty acids are polyunsaturated fatty acids with a final carbon-carbon double bond in the n-6 ... Vegetable oil is a major dietary sources of omega-6 fatty acids. ... molecules with either pro-inflammatory and anti-inflammatory effects. …
Matched Categories: … Fatty Acids ... Fatty Acids, Unsaturated …
Talquetamab is a IgG4-PAA bispecific G protein-coupled receptor class C group 5 member D (GPRC5D)-directed CD3 T-cell engager. It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each arm comprising a heavy and light chain. Talquetamab binds to GPRC5D, a cell surface...
Approved
Investigational
Matched Synonyms: … -KAPPA/G4-LAMBDA, ANTI-(HOMO SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP 5 MEMBER D)), AND ... ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), HUMANIZED AND CHIMERIC MONOCLONAL ANTIBODY, BISPECIFIC ... -KAPPA/G4-LAMBDA, ANTI-(HOMO SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP 5 MEMBER D)), AND
Matched Description: … arm comprising a heavy and light chain. ... It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each ... Talquetamab binds to GPRC5D, a cell surface receptor expressed predominantly on multiple myeloma cells, and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex. Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions.[L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone. Hydrocortisone was granted FDA approval on 5 August 1952.
Approved
Vet approved
Matched Iupac: … (1R,3aS,3bS,9aR,9bS,10S,11aS)-1,10-dihydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H, …
Matched Description: … [A188387] Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions. ... [L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named …
Matched Mixtures name: … Hydrocortisone and Acetic Acid ... Hydrocortisone and Acetic Acid ... Hydrocortisone and Acetic Acid
Matched Categories: … Alimentary Tract and Metabolism ... Sex Hormones and Insulins ... Hydrocortisone and derivatives ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... hydrocortisone and mydriatics …
Matched Products: … HYDROCORTISON ACIS 10MG ... SANATISON MONO 1/3% ... Rodan and Fields Soothe …
Octinoxate is a cinnamate ester and common ingredient in sunscreen and other skin care products to minimize DNA photodamage. It was originally developed in 1950's as an organic UV-B filter that absorbs UV-B rays from sun. It is often combined with nanoparticles or other water-resistant liposomes in formulations to increase...
Approved
Investigational
Matched Iupac: … 2-ethylhexyl (2E)-3-(4-methoxyphenyl)prop-2-enoate …
Matched Description: … Octinoxate is a cinnamate ester and common ingredient in sunscreen and other skin care products to minimize ... Its use in pharmaceutical and cosmetic formulations is approved by FDA. ... nanoparticles or other water-resistant liposomes in formulations to increase the localization at the epidermis and
Matched Mixtures name: … Acid SPF 20 Capuccino 310-C ... Acid SPF 20 Latte 180-F ... Acid SPF 20 Beige 220-C …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic ... Emollients and Protectives …
Matched Products: … Rain and Shine Liptint With SPF 10 Sunscreen ... Firming and Moisturizing Body ... Resilience Lift Firming Sculpting Face and Neck Spf15 for Dry Skin …
Lanolin is a yellow fat obtained from sheep's wool. It is used as an emollient, cosmetic, and pharmaceutic aid . The US federal code of regulations states that lanolin in the concentration range of 12-50% may be included in over the counter skin ointments . Lanolin is the purified, secreted...
Approved
Matched Synonyms: … Wool fat ... Fats, lanolin …
Matched Description: … Lanolin is a yellow fat obtained from sheep's wool. ... It is used as an emollient, cosmetic, and pharmaceutic aid [L2580]. ... Lanolin is used in the protection, treatment, and cosmetic enhancement of human skin. …
Matched Mixtures name: … DURATEARS STERIL OKULER LUBRIKANT POMAD, 3.5 GR ... MAKRA TATTOO SUNSCREEN and SKIN PROTECTANT Broad Spectrum SPF 30 ... Vitamins A and D Diaper Rash …
Matched Categories: … Basic Ointments and Protectants …
Matched Products: … Soothe and Cool Free Medseptic Skin Protectant ... 3ce Drawing Lip Chilling …
Suratadenoturev is a gene-modified oncolytic adenovirus expressing the telomerase reverse transcriptase gene.
Investigational
Matched Synonyms: … telomerase reverse transcriptase (hTERT) and IRES, respectively. ... -5) in which the E1 gene, including its normal transcriptional regulatory element, has been deleted and ... A replication-competent adenovirus type 5 in which the E1A and E1B genes are under the control of a human …
Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up 25% of the mixture. Labetalol is formulated as an injection or tablets to treat hypertension.[L7727,L7730] Labetalol was granted FDA approval on 1 August 1984.
Approved
Matched Synonyms: … 3-Carboxamido-4-hydroxy-alpha-((1-methyl-3-phenylpropylamino)methyl)benzyl alcohol ... 5-(1-Hydroxy-2-(1-methyl-3-phenylpropylamino)ethyl)salicylamide …
Matched Salts name: … Labetalol hydrochloride
Matched Categories: … Alpha and Beta Blocking Agents and Thiazides ... Alpha and Beta Blocking Agents ... Beta Blocking Agents and Thiazides ... labetalol and thiazides ... labetalol and other diuretics …
Matched Products: … BLOCAMINE (Labetalol hydrochloride 5 mg/ml solution for Injection and for Infusion) ... Labetalol Hydrochloride ... Labetalol hydrochloride
AB-201 is a CAR-NK cell therapy targeted against HER2. It is under investigation for the treatment of HER2-positive cancers, including breast and gastric carcinomas.
Investigational
Matched Synonyms: … allogeneic cord blood-derived NK cells that have been genetically modified to express a HER2-directed CAR and
Matched Description: … [L48340] It is under investigation for the treatment of HER2-positive cancers, including breast and gastric …
OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human gp91phox gene. It is being investigated for the treatment of X-linked chronic granulomatous disease.
Investigational
Matched Synonyms: … Autologous CD34+ enriched cell population that contains hematopoietic stem and progenitor cells transduced …
Matched Description: … OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells …
Haemophilus influenzae type b strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen is an active immunization as a booster dose given intramuscularly to pediatric patients who have received a primary series with a Haemophilus b Conjugate Vaccine that is licensed for primarly immunization. The vaccine contains Haemophilus b capsular polysaccharide...
Approved
Investigational
Matched Synonyms: … Haemophilus influenzae type B-PRP and tetanus toxoid conjugate (PRP-T) …
Matched Description: … These are heat inactivated and purified. …
Thrombotic thrombocytopenic purpura (TTP) is a rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and various degrees of organ damage. It may be inherited (congenital TTP; cTTP) or acquired due to autoantibodies (immune-mediated TTP; iTTP), although cTTP accounts for <5% of all cases of TTP. Patients with cTTP...
Approved
Investigational
Matched Synonyms: … Recombinant disintegrin and metalloprotease with thrombospondin type 1 motifs …
Matched Description: … rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and ... Patients with cTTP have a severe deficiency of a plasma metalloproteinase called ADAMTS13 (a disintegrin and ... thrombospondin type 1 motif, member 13), which is responsible for cleaving large von Willebrand factor multimers and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Benzethonium is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties. Its salt form, benzethonium chloride, is primarily used as a skin disinfectant at concentrations of 0.1-0.2 %, which are safe and effective concentrations for the compound specified by the U.S. Food and Drug Administration (FDA)....
Approved
Matched Description: … It is additionally found in cosmetics and toiletries such as mouthwashes and anti-itch ointments. ... Food and Drug Administration (FDA). ... Benzethonium is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum …
Matched Mixtures name: … Salicylic Acid ... Benzethonium Chloride and Dyclonine Hydrochloride ... Benzethonium chloride and Dyclonine hydrochloride
Matched Categories: … Antiseptics and Disinfectants …
Matched Products: … LYSOL Healthy Touch Cleansing Green Tea and Ginger ... LYSOL Healthy Touch Aloe Vera And Vitamin E with Moisturizers ... Foaming Instant Hand Sanitizer with Aloe and Vitamin E …
Calcium carbonate is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. Subsequent increases in pH may inhibit the action of pepsin. An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects. Calcium carbonate may also...
Approved
Investigational
Matched Synonyms: … Carbonic acid calcium salt (1:1) …
Matched Description: … It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. ... An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects. …
Matched Mixtures name: … Calcium Folic Acid Plus D Chewable ... PNV Ferrous Fumarate Docusate Folic Acid ... Berkley and Jensen Acid Controller Complete …
Matched Categories: … ascorbic acid (vit C) and calcium ... Carbonic Acid ... Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders ... Alimentary Tract and Metabolism …
Matched Products: … ACID STOP ... Medique Ban-acid Maximum Strength 750 ... HEB Lime and Berry Antacid Chews …
Trichloroacetate, or trichloroacetic acid, is a strong acid prepared by the reaction of chlorine with acetic acid in the presence of a suitable catalyst. In clinical chemistry and biochemistry, it is used as a precipitant of macromolecules including proteins, DNA and RNA. Trichloroacetate is also found in cosmetic treatments and...
Approved
Matched Description: … Trichloroacetate, or trichloroacetic acid, is a strong acid prepared by the reaction of chlorine with ... acetic acid in the presence of a suitable catalyst. ... , DNA and RNA. …
Matched Salts name: … Trichloroacetic acid
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Trichloroacetic Acid
Matched Products: … Trichloroacetic Acid 30% ... Trichloroacetic Acid 15% ... Trichloroacetic Acid 5% …
Displaying drugs 226 - 250 of 4669 in total