Displaying drugs 2576 - 2600 of 3214 in total
Pristimerin
Pristimerin is a quinone methide triterpenoid researched for its anti-cancer potential.
Investigational
Matched Synonyms: … .)-3-hydroxy-9,13-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid ... 24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid, 3-hydroxy-9,13-dimethyl-2-oxo-, methyl ester, …
Carbenicillin
Broad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function.
Approved
Investigational
Matched Synonyms: … N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)hept-6-yl)-2-phenylmalonamic acid ... -6-{[carboxy(phenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Iupac: … )-6-(2-carboxy-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … It is susceptible to gastric juice and penicillinase and may damage platelet function. …
Matched Iupac: … )-6-(2-carboxy-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … It is susceptible to gastric juice and penicillinase and may damage platelet function. …
Reserpine
An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool,...
Approved
Investigational
Withdrawn
Matched Synonyms: … 16beta,17alpha,18beta,20alpha)-11,17-Dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic acid …
Matched Description: … An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. ... It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse ... serotonin from central and peripheral axon terminals. …
Matched Categories: … reserpine and diuretics ... reserpine and diuretics, combinations with other drugs ... reserpine and diuretics, combinations with psycholeptics …
Matched Description: … An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. ... It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse ... serotonin from central and peripheral axon terminals. …
Matched Categories: … reserpine and diuretics ... reserpine and diuretics, combinations with other drugs ... reserpine and diuretics, combinations with psycholeptics …
VPO-227
Investigational
Matched Synonyms: … phenyl-8-oxa-1,12,14-triazatetracyclo[8.7.0.02,7.011,16]heptadeca-2(7),3,5,10,16-pentaene-4-carboxylic acid …
Matched Iupac: … -8-oxa-1,12,14-triazatetracyclo[8.7.0.0^{2,7}.0^{11,16}]heptadeca-2,4,6,10,16-pentaene-4-carboxylic acid …
Matched Iupac: … -8-oxa-1,12,14-triazatetracyclo[8.7.0.0^{2,7}.0^{11,16}]heptadeca-2,4,6,10,16-pentaene-4-carboxylic acid …
Piracetam
Piracetam is a nootropic drug in the racetams group, with chemical name 2-oxo-1-pyrrolidine acetamide. It shares the same 2-oxo-pyrrolidone base structure with pyroglutamic acid and is a cyclic derivative of the neurotransmitter γ-aminobutyric acid (GABA). However its mechanism of action differ from that of endogenous GABA. Piracetam has neuroprotective and...
Approved
Investigational
Matched Description: … It shares the same 2-oxo-pyrrolidone base structure with pyroglutamic acid and is a cyclic derivative ... Piracetam has neuroprotective and anticonvulsant properties and is reported to improve neural plasticity ... of the neurotransmitter γ-aminobutyric acid (GABA). …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics ... Acids, Acyclic ... Carboxylic Acids …
Matched Products: … PIRACETAM TABLETAS RECUBIERTAS POR 800 MG …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics ... Acids, Acyclic ... Carboxylic Acids …
Matched Products: … PIRACETAM TABLETAS RECUBIERTAS POR 800 MG …
Oxacillin
An antibiotic similar to flucloxacillin used in resistant staphylococci infections.
Approved
Investigational
Matched Synonyms: … 6β-(5-methyl-3-phenylisoxazol-4-yl)penicillanic acid ... 5-methyl-3-phenylisoxazol-4-yl)carbonyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Iupac: … dimethyl-6-(5-methyl-3-phenyl-1,2-oxazole-4-amido)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Salts name: … Oxacillin sodium monohydrate ... Oxacillin sodium …
Matched Iupac: … dimethyl-6-(5-methyl-3-phenyl-1,2-oxazole-4-amido)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Salts name: … Oxacillin sodium monohydrate ... Oxacillin sodium …
Pixofisiran
Investigational
Matched Synonyms: … Cotsiranib tgf-.beta.1 si-rna free acid component ... Stp-705 component tgf-.beta.1 si-rna free acid ... Tgf-.beta.1 si-rna free acid component of cotsiranib …
Matched Salts name: … Pixofisiran sodium …
Matched Salts name: … Pixofisiran sodium …
nor-NOHA
N-Hydroxy-nor-L-arginine (nor-NOHA) is under investigation in clinical trial NCT02009527 (Arginase Inhibition in Ischemia-reperfusion Injury).
Investigational
Matched Synonyms: … (2S)-2-amino-4-(((hydroxyamino)iminomethyl)amino)butanoic acid …
Matched Iupac: … (2S)-2-amino-4-(N'-hydroxycarbamimidamido)butanoic acid …
Matched Iupac: … (2S)-2-amino-4-(N'-hydroxycarbamimidamido)butanoic acid …
1-Methylhistidine
Experimental
Matched Synonyms: … (2S)-2-amino-3-(1-methyl-1H-imidazol-4-yl)propanoic acid …
Matched Iupac: … (2S)-2-amino-3-(1-methyl-1H-imidazol-4-yl)propanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic …
Matched Iupac: … (2S)-2-amino-3-(1-methyl-1H-imidazol-4-yl)propanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic …
N-methylnicotinamide
N-methylnicotinamide is an experimental drug with no approved indication or marketed formulation. It is a metabolite of niacinamide/nicotinamide and niacin/nicotinic acid (vitamin B3), and as such N-methylnicotinamide is used to diagnose niacin deficiency by measuring N-methylnicotinamide in the urine.
Experimental
Matched Synonyms: … Nicotinic acid methylamide …
Matched Description: … It is a metabolite of niacinamide/nicotinamide and niacin/nicotinic acid (vitamin B3), and as such N-methylnicotinamide …
Matched Categories: … Bile and Liver Therapy ... Alimentary Tract and Metabolism ... Acids, Heterocyclic ... Nicotinic Acids …
Matched Description: … It is a metabolite of niacinamide/nicotinamide and niacin/nicotinic acid (vitamin B3), and as such N-methylnicotinamide …
Matched Categories: … Bile and Liver Therapy ... Alimentary Tract and Metabolism ... Acids, Heterocyclic ... Nicotinic Acids …
Mavodelpar
Investigational
Matched Synonyms: … REN-001 free acid …
Matched Iupac: … fluorophenyl)-3-{4-[3-(morpholin-4-yl)prop-1-yn-1-yl]phenyl}prop-2-en-1-yl]oxy}-2-methylphenoxy)acetic acid …
Matched Salts name: … Mavodelpar sodium …
Matched Iupac: … fluorophenyl)-3-{4-[3-(morpholin-4-yl)prop-1-yn-1-yl]phenyl}prop-2-en-1-yl]oxy}-2-methylphenoxy)acetic acid …
Matched Salts name: … Mavodelpar sodium …
Vancomycin
Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear.
As of January 29 2018, CutisPharma's Firvanq is the only FDA approved vancomycin oral liquid treatment option available for the the treatment of...
Approved
Matched Iupac: … }.0^{34,39}]pentaconta-3,5,8,10,12(48),14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid …
Matched Description: … kidneys and the inner ear. ... It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to ... liquid treatment option available for the the treatment of _Clostridium difficile_ associated diarrhea and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism …
Matched Products: … Vancomycin Injection USP In 0.9% Sodium Chloride …
Matched Description: … kidneys and the inner ear. ... It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to ... liquid treatment option available for the the treatment of _Clostridium difficile_ associated diarrhea and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism …
Matched Products: … Vancomycin Injection USP In 0.9% Sodium Chloride …
Ethiodized oil
Ethiodized oil is used by injection as a radio-opaque contrast agent. The composition of the oil is comprised of iodine combined with ethyl esters of fatty acids of poppyseed oil. And although these esters are primarily as ethyl monoiodostearate and ethyl diiodostearate, the actual, specific structure is unknown.
Approved
Investigational
Matched Synonyms: … IODIZED ETHYL ESTERS OF POPPYSEED FATTY ACIDS …
Matched Description: … And although these esters are primarily as ethyl monoiodostearate and ethyl diiodostearate, the actual ... The composition of the oil is comprised of iodine combined with ethyl esters of fatty acids of poppyseed …
Matched Categories: … ethyl esters of iodised fatty acids …
Matched Description: … And although these esters are primarily as ethyl monoiodostearate and ethyl diiodostearate, the actual ... The composition of the oil is comprised of iodine combined with ethyl esters of fatty acids of poppyseed …
Matched Categories: … ethyl esters of iodised fatty acids …
Hydrogenated soybean oil
Extracted from the seeds of the soybean (Glycine soja), hydrogenated soybean oil is a major food fat used in the production of margarine, shortening, and salad and cooking oils. According to the FDA, hydrogenated soybean oil is generally recognized as safe (GRAS) food substance. Linolenic acid and stearic acids are...
Experimental
Matched Synonyms: … Soya bean oil fatty acids, hydrogenated …
Matched Description: … Linolenic acid and stearic acids are contained in hydrogenated soybean oil, but hydrogenation results ... salad and cooking oils. ... soja), hydrogenated soybean oil is a major food fat used in the production of margarine, shortening, and …
Matched Description: … Linolenic acid and stearic acids are contained in hydrogenated soybean oil, but hydrogenation results ... salad and cooking oils. ... soja), hydrogenated soybean oil is a major food fat used in the production of margarine, shortening, and …
Fish oil
Fish oil is a component of SMOFLIPID, which was FDA approved in July 2016. It is indicated in adults as a source of calories and essential fatty acids for parenteral nutrition when oral or enteral nutrition is not possible, insufficient, or contraindicated.
More commonly, fish oil refers to the omega-3-fatty...
Approved
Nutraceutical
Matched Synonyms: … Fish oil containing omega-3 acids …
Matched Description: … More commonly, fish oil refers to the omega-3-fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic ... It is indicated in adults as a source of calories and essential fatty acids for parenteral nutrition ... However, prescription-only fish oil products are sometimes prescribed for individuals who demonstrate …
Matched Categories: … Calcium Channel Blockers …
Matched Description: … More commonly, fish oil refers to the omega-3-fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic ... It is indicated in adults as a source of calories and essential fatty acids for parenteral nutrition ... However, prescription-only fish oil products are sometimes prescribed for individuals who demonstrate …
Matched Categories: … Calcium Channel Blockers …
Levofloxacin
Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic ofloxacin. It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive bacteria compared to R-(+)-ofloxacin and remains stereochemically stable following administration (i.e. it does not invert to the inactive isomer). Levofloxacin, along with other quinolones...
Approved
Investigational
Matched Synonyms: … methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid ... dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid ... methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzooxazine-6-carboxylic acid …
Matched Iupac: … methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13),6,8,11-tetraene-11-carboxylic acid …
Matched Description: … several South American countries soon after. ... Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic [ofloxacin]. ... [A31453,A190756] Levofloxacin was first approved by the FDA in 1996, and was approved in Canada and …
Matched Categories: … Alimentary Tract and Metabolism ... levofloxacin and ornidazole ... Metabolic Side Effects of Drugs and Substances ... lansoprazole, amoxicillin and levofloxacin …
Matched Iupac: … methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13),6,8,11-tetraene-11-carboxylic acid …
Matched Description: … several South American countries soon after. ... Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic [ofloxacin]. ... [A31453,A190756] Levofloxacin was first approved by the FDA in 1996, and was approved in Canada and …
Matched Categories: … Alimentary Tract and Metabolism ... levofloxacin and ornidazole ... Metabolic Side Effects of Drugs and Substances ... lansoprazole, amoxicillin and levofloxacin …
Chloroprocaine
Chloroprocaine is an ester local anesthetic commonly available in its salt form, chloroprocaine hydrochloride. Similar to other local anesthetics, it increases the threshold for electrical excitation in nerves by slowing the propagation of the nerve impulse and reducing the rate of rise of the action potential. The pharmacological profile of...
Approved
Investigational
Matched Synonyms: … 4-amino-2-chlorobenzoic acid 2-(diethylamino)ethyl ester …
Matched Description: … [A252952] Chloroprocaine can be given as an injection, and is available in formulations with and without ... formulation can be used for lumbar and caudal epidural blocks. ... increases the threshold for electrical excitation in nerves by slowing the propagation of the nerve impulse and …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Esters of Aminobenzoic Acid …
Matched Description: … [A252952] Chloroprocaine can be given as an injection, and is available in formulations with and without ... formulation can be used for lumbar and caudal epidural blocks. ... increases the threshold for electrical excitation in nerves by slowing the propagation of the nerve impulse and …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Esters of Aminobenzoic Acid …
RU85053
Experimental
Matched Synonyms: … Acetamido-3-oxo-3-[[(3S)-2-oxo-1-[(4-phenylphenyl)methyl]azepan-3-yl]amino]propyl]-2-(carboxymethyl)benzoic acid …
Matched Iupac: … [1,1'-biphenyl]-4-yl}methyl)-2-oxoazepan-3-yl]carbamoyl}-2-acetamidoethyl]-2-(carboxymethyl)benzoic acid …
Matched Iupac: … [1,1'-biphenyl]-4-yl}methyl)-2-oxoazepan-3-yl]carbamoyl}-2-acetamidoethyl]-2-(carboxymethyl)benzoic acid …
Acrivastine
Acrivastine is a triprolidine analog antihistamine indicated for the treatment of allergies and hay fever. As an H1 receptor antagonist, it functions by blocking the action of histamine at this receptor thereby preventing the symptoms associated with histamine release such as pruritis, vasodilation, hypotension, edema, bronchoconstriction, and tachycardia.
Acrivastine is...
Approved
Matched Synonyms: … (2E)-3-{6-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridin-2-yl}acrylic acid …
Matched Iupac: … (2E)-3-{6-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridin-2-yl}prop-2-enoic acid …
Matched Description: … Acrivastine is a triprolidine analog antihistamine indicated for the treatment of allergies and hay fever ... associated with histamine release such as pruritis, vasodilation, hypotension, edema, bronchoconstriction, and …
Matched Iupac: … (2E)-3-{6-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridin-2-yl}prop-2-enoic acid …
Matched Description: … Acrivastine is a triprolidine analog antihistamine indicated for the treatment of allergies and hay fever ... associated with histamine release such as pruritis, vasodilation, hypotension, edema, bronchoconstriction, and …
Cianidanol
An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin (cis) forms.
Approved
Withdrawn
Matched Synonyms: … Catechuic acid …
Matched Description: … An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin …
Matched Description: … An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin …
Vipoglanstat
Investigational
Matched Synonyms: … dimethyl-propionylamino)-methyl]-phenylamino}-6-(2,2-difluoroethoxy)-1-methyl-1H-benzoimidazole-5-carboxylic acid …
Perindopril
Perindopril is a nonsulfhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration. Perindoprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to...
Approved
Matched Synonyms: … 3aS,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]octahydro-1H-indole-2-carboxylic acid …
Matched Iupac: … 3aS,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]-octahydro-1H-indole-2-carboxylic acid …
Matched Description: … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS ... be used to treat mild to moderate essential hypertension, mild to moderate congestive heart failure, and ... to reduce the cardiovascular risk of individuals with hypertension or post-myocardial infarction and …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... atorvastatin, acetylsalicylic acid and perindopril ... ACE Inhibitors and Diuretics ... perindopril and diuretics ... perindopril and bisoprolol …
Matched Iupac: … 3aS,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]-octahydro-1H-indole-2-carboxylic acid …
Matched Description: … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS ... be used to treat mild to moderate essential hypertension, mild to moderate congestive heart failure, and ... to reduce the cardiovascular risk of individuals with hypertension or post-myocardial infarction and …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... atorvastatin, acetylsalicylic acid and perindopril ... ACE Inhibitors and Diuretics ... perindopril and diuretics ... perindopril and bisoprolol …
4-[Hydroxy-[Methyl-Phosphinoyl]]-3-Oxo-Butanoic Acid
Experimental
Matched Name: … 4-[Hydroxy-[Methyl-Phosphinoyl]]-3-Oxo-Butanoic Acid …
Matched Iupac: … 4-[hydroxy(methyl)phosphoryl]-3-oxobutanoic acid …
Matched Iupac: … 4-[hydroxy(methyl)phosphoryl]-3-oxobutanoic acid …
(2s,3s)-Trans-2,3-Dihydro-3-Hydroxyanthranilic Acid
Experimental
Matched Name: … (2s,3s)-Trans-2,3-Dihydro-3-Hydroxyanthranilic Acid …
Matched Iupac: … (5S,6S)-6-amino-5-hydroxycyclohexa-1,3-diene-1-carboxylic acid …
Matched Iupac: … (5S,6S)-6-amino-5-hydroxycyclohexa-1,3-diene-1-carboxylic acid …
Displaying drugs 2576 - 2600 of 3214 in total