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Displaying drugs 251 - 275 of 2893 in total
Leuprolide is a synthetic 9-residue peptide analogue of gonadotropin-releasing hormone (GnRH). Unlike the endogenous decapeptide GnRH, leuprolide contains a single D-amino acid (D-leucyl) residue, which helps to increase its circulating half-life from three to four minutes to approximately three hours. As a GnRH mimic, leuprolide is capable of binding to...
Approved
Investigational
Matched Description: … Unlike the endogenous decapeptide GnRH, leuprolide contains a single D-amino acid (D-leucyl) residue, ... downstream modulation of both gonadotropin hormone and sex steroid levels. ... [A203222] As a GnRH mimic, leuprolide is capable of binding to the GnRH receptor (GnRHR) and inducing …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Hormones and Related Agents ... leuprorelin and bicalutamide …
Matched Products: … POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 45mg ... POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 22.5mg ... POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 7.5mg …
Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an exceptionally commonly used medication . In particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs the sensations of tissues means the agent is indicated for facilitating local...
Approved
Vet approved
Matched Synonyms: … alpha-diethylamino-2,6-dimethylacetanilide …
Matched Description: … Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an ... , it can block or decrease muscle contractile, resulting in effects like vasodilation, hypotension, and ... It ultimately elicits its numbing activity by blocking sodium channels so that the neurons of local tissues …
Matched Mixtures name: … Hyaluronic Acid 60mg and Lidocaine 2% PF ... Cimetidine 10% / Lidocaine 5% / Salicylic Acid 40% ... Lidocaine Hydrochloride and Epinephrine …
Matched Categories: … Analgesics and Anesthetics ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Antipruritics and Local Anesthetics ... Sodium Channel Blockers ... Voltage-Gated Sodium Channel Blockers …
Matched Products: … Zingo ... Terrasil Rash and Pain Relief ... Terrasil Itch, Rash and Pain Relief MAX …
Oxymetazoline is an imidazole derivative and a potent, direct-acting alpha (α)-adrenergic agonist with affinity to both α1- and α2-adrenoceptors. Oxymetazoline is available in various formulations with a wide variety of clinical implications. The topical formulation of the drug is used to treat persistent facial redness in adults. As an effective...
Approved
Investigational
Matched Description: … Oxymetazoline is an imidazole derivative and a potent, direct-acting alpha (α)-adrenergic agonist with ... affinity to both α1- and α2-adrenoceptors. ... is used for regional anesthesia during dental procedures in children and adults. …
Matched Mixtures name: … Mucinex Sinus-Max Pressure, Pain and Cough and Mucinex Sinus-Max Severe Congestion Relief Clear and Cool …
Matched Categories: … Decongestants and Antiallergics ... Adrenergic alpha-Agonists ... Adrenergic alpha-1 Receptor Agonists ... Adrenergic alpha-2 Receptor Agonists …
Matched Products: … Breaze Nasal Sinus Colds and Allergies ... Up and Up nasal ... Up and up nasal …
NKX101 is an investigational allogeneic chimeric antigen receptor (CAR)-natural killer cell therapy.
Investigational
Matched Synonyms: … NK) cell therapy engineered with an NKG2D ACR, OX40 costimulatory domain, CD3zeta signaling moiety, and
Investigational
Matched Synonyms: … Fc-fusion protein comprised of an anti-CXCR4 i-body tethered at its C-terminus to constant domains 2 and
Tioconazole is an imidazole antifungal used to treat fungal and yeast infections. Topical formulations are used for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus". Tioconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the yeast membrane. In...
Approved
Matched Description: … Tioconazole is an imidazole antifungal used to treat fungal and yeast infections. ... Topical formulations are used for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus ... Tioconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme that converts lanosterol to …
Matched Categories: … 14-alpha Demethylase Inhibitors ... Genito Urinary System and Sex Hormones ... Imidazole and Triazole Derivatives ... Gynecological Antiinfectives and Antiseptics ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … Up and up tioconazole 1 ... Foster and Thrive Tioconazole …
Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation.[A233300,L13362] Both bisacodyl and picosulfate are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).[A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956 but has been used as a laxative since 1952.
Approved
Matched Description: … [A233300,L13362] Both bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-( …
Matched Mixtures name: … HalfLytely and Bisacodyl ... HalfLytely and Bisacodyl ... GaviLyte-H and Bisacodyl …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Up and Up womens laxative ... Up and Up Gentle Laxative ... Gentle and Effective Laxative Enteric Coated …
Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms. It is one of the most common skin and mucous membrane antiseptic agents in use today. The molecule itself is a cationic bis-guanide consisting of...
Approved
Vet approved
Withdrawn
Matched Description: … Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental ... [L11512] It is one of the most common skin and mucous membrane antiseptic agents in use today. ... [A190417] The molecule itself is a cationic bis-guanide consisting of two 4-chlorophenyl rings and two …
Matched Mixtures name: … RinsCap CIPA ( CHLORHEXIDINE GLUCONATE 2% w/v and ISOPROPYL ALCOHOL 70% v/v ) ... QCare Rx Oral Cleansing and Suctioning System, Q4 ... QCare Rx Oral Cleansing and Suctioning System …
Matched Salts name: … Chlorhexidine gluconate
Matched Categories: … Alimentary Tract and Metabolism ... Biguanides and Amidines ... Antiseptics and Disinfectants ... Antiinfectives and Antiseptics for Local Oral Treatment ... Mouthwashes and Gargles …
Matched Products: … 3M AVAGARD 9232 ANTISEPTIC HAND AND BODY WASH CLORHEXIDINE GLUCONATE 2% W/W SOLUTION BOTTE . ... Foster and Thrive ... Chlorhexidine Gluconate
Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid. Triethanolamine neutralizes the acidity of the salicylic acid. It is a topical analgesic used for temporary relief of minor pain associated with arthritis, simple backache, muscle strains, sprains, and bruises. Unlike other topical analgesics, trolamine...
Approved
Matched Iupac: … 2-[bis(2-hydroxyethyl)amino]ethan-1-ol; 2-hydroxybenzoic acid
Matched Description: … Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid ... Triethanolamine neutralizes the acidity of the salicylic acid. ... temporary relief of minor pain associated with arthritis, simple backache, muscle strains, sprains, and
Matched Categories: … Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids
Matched Products: … Up and Up Pain Relief Odorless ... Up and Up Odor-free Pain Relieving Cream ... Tommie Copper Pain Relief …
Cetirizine, also commonly known as Zyrtec, is an orally active second-generation histamine H1 antagonist proven effective in the treatment of various allergic symptoms, such as sneezing, coughing, nasal congestion, hives, and other symptoms , . One of the most common uses for this drug is for a condition called allergic...
Approved
Matched Iupac: … 2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid
Matched Description: … in the treatment of various allergic symptoms, such as sneezing, coughing, nasal congestion, hives, and ... prevalence of allergic rhinitis in the United States is about 15% according to physician diagnoses, and ... with sleep, and other difficulties with day to day activities for many individuals [A175057]. …
Matched Mixtures name: … Cetirizine HCl and Pseudoephedrine HCl ER ... ZYRTEC D Allergy and Congestion ... Cetirizine HCl and Pseudoephedrine HCl ER …
Matched Categories: … Cetirizine and isomer ... Decongestants and Antiallergics …
Matched Products: … ZINE ... Up and Up Allergy Relief ... Up and Up Childrens All Day Allergy Relief …
Methyl cellulose polymer consisting of numerous linked glucose molecules used as a stabiliser, thickener and emulsifier for foodstuffs and cosmetics. The Degree of Substitution (DS) of a given form of methyl cellulose is defined as the average number of substituted hydroxyl groups per glucose with a theoretical maximum of 3,...
Approved
Matched Description: … emulsifier for foodstuffs and cosmetics. ... Methyl cellulose polymer consisting of numerous linked glucose molecules used as a stabiliser, thickener and ... Like cellulose, it is not digestible, not toxic, and not allergenic …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Foster and Thrive Fiber Laxative 188 …
An isomer of 1-propanol. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.
Approved
Investigational
Matched Description: … It is used in the manufacture of acetone and its derivatives and as a solvent. …
Matched Mixtures name: … RinsCap CIPA ( CHLORHEXIDINE GLUCONATE 2% w/v and ISOPROPYL ALCOHOL 70% v/v ) ... Chlorhexidine Gluconate Applicator ... Chlorhexidine Gluconate Applicator …
Matched Categories: … Antiseptics and Disinfectants …
Matched Products: … Clean Skin club Hydrating Hand Sanitizer with Aloe Vera and Hyaluronic Acid ... Alpet E-3 ... Alpet E3 Hand Sanitizer Spray …
Investigational
Matched Synonyms: … immunoglobulin g1 (igg1) t-cell bispecific (tcb) antibody targeting carcinoembryonic antigen (cea) and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Lym-1-I-131 is a monoclonal antibody labeled with iodine-131 (131I) that preferentially targets malignant lymphocytes.
Investigational
Matched Synonyms: … Murine MAb (Lym-1) and Iodine 131-I radiolabeled murine MAb (Lym-1) to human B-cell lymphoma …
Lanolin is a yellow fat obtained from sheep's wool. It is used as an emollient, cosmetic, and pharmaceutic aid . The US federal code of regulations states that lanolin in the concentration range of 12-50% may be included in over the counter skin ointments . Lanolin is the purified, secreted...
Approved
Matched Description: … It is used as an emollient, cosmetic, and pharmaceutic aid [L2580]. ... Lanolin is used in the protection, treatment, and cosmetic enhancement of human skin. ... as an active ingredient in over the counter topical products such as ointments, lubricants, lotions and
Matched Mixtures name: … Alpha Keri ... Vitamins A and D Diaper Rash ... PETROLATUM and LANOLIN …
Matched Categories: … Basic Ointments and Protectants …
Matched Products: … Soothe and Cool Free Medseptic Skin Protectant …
This drug is a broad spectrum antimycotic or antifungal agent. Clotrimazole's antimycotic properties were discovered in the late 1960s . Clotrimazole falls under the imidazole category of azole antifungals, possessing broad-spectrum antimycotic activity . It is available in various preparations, including creams, pessaries, and troche formulations (slowly dissolving tablets). As...
Approved
Vet approved
Matched Description: … It is available in various preparations, including creams, pessaries, and troche formulations (slowly ... has become a drug of interest in treating several other diseases such as sickle cell disease, malaria and ... The minimal side effect profile of this drug and its uncomplicated metabolic profile have led it to gain …
Matched Mixtures name: … CLOTRIMAZOL ACIS 3 KOMBI ... CLOTRIMAZOL ACIS 3 KOMBI ... Clotrimazole and Betamethasone Dipropionate …
Matched Categories: … Antiinfectives and Antiseptics for Local Oral Treatment ... Imidazole and Triazole Derivatives ... Gynecological Antiinfectives and Antiseptics ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Terrasil Foot and Nail Anti-Fungal ... Up and Up Jock Itch Relief ... Protective Nail and skin …
NGN-401 is a recombinant serotype 9 adeno-associated virus (AAV) encoding an intron encoding a miRNA generating sequence, complementary miRNA binding sites and a full-length human methyl cytosine binding protein 2 (MECP2). Developed by Neurogene Inc., it is being investigated for the treatment of Rett syndrome.
Investigational
Matched Synonyms: … virus (AAV) encoding an intron encoding a miRNA generating sequence, complementary miRNA binding sites and
Matched Description: … virus (AAV) encoding an intron encoding a miRNA generating sequence, complementary miRNA binding sites and
AOC-1020 is an antibody oligonucleotide conjugate, comprised of a human transferrin receptor 1 targeting, effector function null, humanized IgG1 antibody, a MCC maleimide linker, and a double-stranded siRNA oligonucleotide targeting DUX4.
Investigational
Matched Synonyms: … transferrin receptor 1 targeting, effector function null, humanized IgG1 antibody, a MCC maleimide linker, and
Matched Description: … transferrin receptor 1 targeting, effector function null, humanized IgG1 antibody, a MCC maleimide linker, and
Diphenhydramine - perhaps known most commonly as its brand name formulation Benadryl - is a first-generation H1 receptor antihistamine that is used extensively for the treatment of seasonal allergies, insect bites and stings, and rashes [L5263, L5266, L5269, F3379]. However, it also has antiemetic, antitussive, hypnotic, and antiparkinson properties [L5269,...
Approved
Investigational
Matched Description: … stings, and rashes [L5263, L5266, L5269, F3379]. ... receptor antihistamine that is used extensively for the treatment of seasonal allergies, insect bites and ... However, it also has antiemetic, antitussive, hypnotic, and antiparkinson properties [L5269, F3352]. …
Matched Mixtures name: … Diphenhydramine HCl and Zinc Acetate ... Diphenhydramine HCl and Zinc Acetate ... Diphenhydramine HCl and Zinc Acetate …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Hypnotics and Sedatives ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... naproxen and diphenhydramine …
Matched Products: … Up and Up Allergy Relief ... Up and Up Nighttime Sleep-aid ... Berkley and Jensen Allergy …
Loperamide is an anti-diarrheal agent that is available as various over-the-counter products for treating diarrhea. The drug was first synthesized in 1969 and used medically in 1976. It is a highly lipophilic synthetic phenylpiperidine opioid that is structurally similar to opiate receptor agonists such as diphenoxylate and haloperidol. Due to...
Approved
Matched Description: … withdrawal symptoms and to induce euphoria. ... [L42785] The drug was first synthesized in 1969 and used medically in 1976. ... [A6249] Due to pharmacological properties, loperamide has been misused and abused to self-manage opioid …
Matched Mixtures name: … Loperamide Hydrochloride and Simethicone ... Up and Up Anti Diarrheal Anti Gas ... Anti Diarrheal and Anti Gas …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Up and Up anti diarrheal ... Berkley and Jensen Anti Diarrheal ... Foster and Thrive Anti-diarrheal …
Loratadine is a second generation antihistamine used to manage symptoms of allergic rhinitis. A lack of sedative and CNS adverse effects make loratadine, along with other second generation antihistamines, preferable over their 1st generation counterparts in many clinical situations.
Approved
Investigational
Matched Description: … [A176435] A lack of sedative and CNS adverse effects make loratadine, along with other second generation …
Matched Mixtures name: … Loratadine and Pseudoephedrine ... Allergy and Congestion Relief Non Drowsy ... Loratadine and Pseudoephedrine …
Matched Categories: … Loratadine and derivatives …
Matched Products: … Up and Up Allergy Relief ... Up and Up Childrens Allergy Relief ... Berkley and Jensen Loratadine Non Drowsy …
Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up 25% of the mixture. Labetalol is formulated as an injection or tablets to treat hypertension.[L7727,L7730] Labetalol was granted FDA approval on 1 August 1984.
Approved
Matched Synonyms: … 3-Carboxamido-4-hydroxy-alpha-((1-methyl-3-phenylpropylamino)methyl)benzyl alcohol …
Matched Categories: … Alpha and Beta Blocking Agents ... Alpha and Beta Blocking Agents and Thiazides ... Beta Blocking Agents and Thiazides ... labetalol and thiazides ... labetalol and other diuretics …
Matched Products: … BLOCAMINE (Labetalol hydrochloride 5 mg/ml solution for Injection and for Infusion) ... Labetalol HCl in Sodium Chloride …
Originally approved by the FDA in 1989, omeprazole is a proton-pump inhibitor, used to treat gastric acid-related disorders. These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases characterized by the oversecretion of gastric acid. This drug was the first clinical useful drug in its class,...
Approved
Investigational
Vet approved
Matched Description: … characterized by the oversecretion of gastric acid. ... Omeprazole is generally effective and well-tolerated, promoting its popular use in children and adults ... These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases …
Matched Mixtures name: … Omeprazole and Sodium Bicarbonate ... Omeprazole and Sodium Bicarbonate ... Omeprazole and Sodium Bicarbonate …
Matched Salts name: … Omeprazole sodium
Matched Categories: … Acid Reducers ... Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders ... Alimentary Tract and Metabolism ... Omeprazole and enantiomer …
Matched Products: … Up and Up Omeprazole ... Berkley and Jensen Omeprazole ... STOMACER
Garcinia gummi-gutta fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Garcinia Cambogia (Constituent of Garcinia Cambogia and Garcinia Indica) …
DCLL9718S is an antibody-drug conjugate targeting C-type lectin-like molecule-1 (CLL-1). DCLL9718S is under investigation in clinical trial NCT03298516 (A Study of DCLL9718S in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) or DCLL9718S in Combination With Azacitidine in Participants With Previously Untreated AML Unsuitable for Intensive Induction Chemotherapy).
Investigational
Matched Synonyms: … antibody drug conjugate comprised of humanized IgG1 anti-C-type lectin-like molecule-1 monoclonal antibody and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 251 - 275 of 2893 in total