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Displaying drugs 276 - 300 of 3330 in total
Dabocemagene autoficel is an ex vivo, autologous cell-based gene therapy. It comprises autologous dermal fibroblasts genetically modified to express functional type VII collagen. Developed by Castle Creek Biosciences Inc., dabocemagene autoficel is being investigated for the treatment of dystrophic epidermolysis bullosa.
Investigational
Matched Synonyms: … AUTOLOGOUS HUMAN DERMAL FIBROBLAST CELLS DERIVED FROM SKIN BIOPSIES, AND TRANSDUCED WITH A NON-REPLICATING ... INTEGRATED PROVIRAL HUMAN COLLAGEN TYPE VII TRANSGENE COL7A1 PLUS 5'-HUMAN CYTOMEGALOVIRUS PROMOTER/UTR-AND ... , SELF-INACTIVATING LENTIVIRUS VECTOR THAT ENCODES HUMAN COLLAGEN TYPE VII ALPHA 1 (COL7A1) UNDER THE …
Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation.[A233300,L13362] Both bisacodyl and picosulfate are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).[A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956 but has been used as a laxative since 1952.
Approved
Matched Iupac: … 4-{[4-(acetyloxy)phenyl](pyridin-2-yl)methyl}phenyl acetate
Matched Description: … [A233300,L13362] Both bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-( …
Matched Mixtures name: … HalfLytely and Bisacodyl ... HalfLytely and Bisacodyl ... GaviLyte-H and Bisacodyl …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Up and Up womens laxative ... Up and Up Gentle Laxative ... Gentle and Effective Laxative Enteric Coated …
Pyrethrum is the crude extract form obtained from flowers of the plant Chrysanthemum cinerariifolium. Pyrethrin refers to a more refined extract of pyrethrum. While pyrethrum extract is composed of 6 esters, both organic compounds mediate insecticidal activities. Pyrethrum-containing mixtures are used as a common insecticide to control specific pest species....
Approved
Matched Synonyms: … Pyrethrins and pyrethroids …
Matched Description: … Pyrethrum extract is also used used to treat head, body, and pubic lice infections. ... The active compound is absorbed by the lice and destroys them by acting on their nervous systems but …
Matched Mixtures name: … Lice-Nil Lice and Eggs Killer ... Medi and Lice Lice Killing ... Weeks and Leo Complete Lice Treatment …
Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral alpha (α)-adrenergic properties. Available since the 1950s, tetryzoline is a selective α1-receptor agonist that is used as an ocular and nasal decongestant. Tetryzoline is found in a wide array of over-the-counter eye drops, including the most...
Approved
Matched Description: … such as [povidone], [polyethylene glycol 400], [dextran], and [zinc sulfate]. ... alpha (α)-adrenergic properties. ... Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral …
Matched Mixtures name: … Redness reliever and Lubricant ... Seasonal itchy and Red eye relief ... Up and Up Ultra Itchy Relief …
Matched Salts name: … Tetrahydrozoline hydrochloride
Matched Categories: … Decongestants and Antiallergics ... Adrenergic alpha-Agonists ... Adrenergic alpha-1 Receptor Agonists …
Matched Products: … Walgreens Eye Drops Original 15mL and twin pack ... Foster and Thrive Original Formula Eye Drops …
Xylometazoline is an imidazoline derivative with sympathomimetic and nasal decongestant activity. Xylometazoline works by binding to alpha (α)-adrenergic receptors to cause vasoconstriction of nasal blood vessels. Xylometazoline is available in over-the-counter (OTC) nasal sprays or drops to temporarily relieve nasal congestion due to cold, hay fever or other respiratory allergies....
Approved
Investigational
Matched Description: … Xylometazoline is an imidazoline derivative [A228523] with sympathomimetic and nasal decongestant activity ... Xylometazoline works by binding to alpha (α)-adrenergic receptors to cause vasoconstriction of nasal …
Matched Salts name: … Xylometazoline hydrochloride
Matched Categories: … Decongestants and Antiallergics ... Adrenergic alpha-Agonists ... Adrenergic alpha-1 Receptor Agonists ... Adrenergic alpha-2 Receptor Agonists …
Matched Products: … Cold and Allergy Decongestant Nasal Spray ... Otrivin Cold and Allergy Decongestant Nose Drops ... Otrivin Allergy and Cold Decongestant Nasal Spray …
Approved
Nutraceutical
Matched Synonyms: … Ascorbic acid calcium salt ... L-ascorbic acid, calcium salt (2:1) ... Calcium ascorbate anhydrous
Matched Mixtures name: … Iron Fumarate and Aspartate, Glycinate, Ascorbic Calcium, Vitamin B12, Folic Acid, Calcium Threonate ... Iron Aspartate Glycinate and Polysaccharide Complex, Ascorbic Calcium, Vitamin B12, Folic Acid, Calcium ... Iron Aspartate, Glycinate, Ascorbic Calcium, Vitamin B12, Calcium Threonate and Succinic Acid
Matched Categories: … Diet, Food, and Nutrition ... Vitamin C and analogues ... Acids, Acyclic ... Carboxylic Acids ... Sugar Acids
Matched Products: … Ester-C With Non-medicinal Bioflavonoids, Quercetin, and Grape Seed Extract …
A water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.
Approved
Investigational
Nutraceutical
Matched Synonyms: … (+)-cis-Hexahydro-2-oxo-1H-thieno[3,4]imidazole-4-valeric acid ... 5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid ... cis-Hexahydro-2-oxo-1H-thieno(3,4)imidazole-4-valeric acid
Matched Iupac: … 5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid
Matched Description: … and milk. ... It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, …
Matched Mixtures name: … Folivane-Plus with Ascorbic Acid Precursors ... B-complex With Vitamin C, Biotin, Folic Acid ... Prenatal Vitamin No 53 Iron Fum Folic Acid Docusate CA DHA …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition ... Enzymes and Coenzymes …
Matched Products: … Biona-vit Controls and Prevents Hair Loss …
Garcinia gummi-gutta fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Garcinia Cambogia (Constituent of Garcinia Cambogia and Garcinia Indica) …
DCLL9718S is an antibody-drug conjugate targeting C-type lectin-like molecule-1 (CLL-1). DCLL9718S is under investigation in clinical trial NCT03298516 (A Study of DCLL9718S in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) or DCLL9718S in Combination With Azacitidine in Participants With Previously Untreated AML Unsuitable for Intensive Induction Chemotherapy).
Investigational
Matched Synonyms: … antibody drug conjugate comprised of humanized IgG1 anti-C-type lectin-like molecule-1 monoclonal antibody and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and secreted by the somatotropic cells of the anterior pituitary gland. Growth hormone plays an essential role in growth regulation during childhood as well as other basal metabolic functions, muscle and fat mass regulation, blood...
Approved
Investigational
Matched Description: … in a strain of _Escherichia coli_, recombinant HGH is a polypeptide hormone that contains 191 amino acid ... fat mass regulation, blood glucose level regulation, and lipid regulation in both children and adults ... Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Anterior Pituitary Lobe Hormones and Analogues ... Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Somatropin and Somatropin Agonists …
Matched Products: … GENOTROPIN® 12MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... GENOTROPIN® 5.3MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ZOMACTON Powder and Solvent for Solution for Injection 10mg …
A potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.
Approved
Investigational
Matched Synonyms: … 2,4-Diamino-6-piperidinopyrimidine 3-oxide ... 6-Piperidin-1-ylpyrimidine-2,4-diamine 3-oxide
Matched Description: … potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and
Matched Mixtures name: … Bakumokon 7% Minoxidil Sulfate
Matched Salts name: … Minoxidil sulfate
Matched Categories: … Skin and Mucous Membrane Agents …
Matched Products: … Up and Up Minoxidil ... Up and Up minoxidil ... Berkley and Jensen Minoxidil …
Dexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Dexpanthenol is enzymatically cleaved to form pantothenic acid, which is an essential component of Coenzyme A, which acts as a cofactor in many enzymatic reactions that...
Approved
Matched Description: … Dexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and ... Due to its good penetration and high local concentrations, dexpanthanol is used in many topical products ... , such as ointments and lotions for treatment of dermatological conditions to relieve itching or promote …
Matched Mixtures name: … Somarexin and C 1000 ... B Complex W C and B12 Inj ... CH6 Perfumed Aloforthya Peony and the sunset …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Alimentary Tract and Metabolism ... Vitamin D and Analogues ... Preparations for Treatment of Wounds and Ulcers …
Matched Products: … Eros Aqua Sensations and Care Woman ... DEXPANTHENOL ACIS WUND+HEI …
This drug is a broad spectrum antimycotic or antifungal agent. Clotrimazole's antimycotic properties were discovered in the late 1960s . Clotrimazole falls under the imidazole category of azole antifungals, possessing broad-spectrum antimycotic activity . It is available in various preparations, including creams, pessaries, and troche formulations (slowly dissolving tablets). As...
Approved
Vet approved
Matched Description: … It is available in various preparations, including creams, pessaries, and troche formulations (slowly ... has become a drug of interest in treating several other diseases such as sickle cell disease, malaria and ... The minimal side effect profile of this drug and its uncomplicated metabolic profile have led it to gain …
Matched Mixtures name: … CLOTRIMAZOL ACIS 3 KOMBI ... CLOTRIMAZOL ACIS 3 KOMBI ... Clotrimazole and Betamethasone Dipropionate …
Matched Categories: … Antiinfectives and Antiseptics for Local Oral Treatment ... Imidazole and Triazole Derivatives ... Gynecological Antiinfectives and Antiseptics ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Terrasil Foot and Nail Anti-Fungal ... Up and Up Jock Itch Relief ... Protective Nail and skin …
Insulin aspart is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … with aspartic acid. ... body starts to break down fat, instead of glucose, for energy which results in a build-up of ketone acids ... Compared to human insulin, it has a single amino acid substitution at position B28 where proline is replaced …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... insulin degludec and insulin aspart ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Insulins and Analogues for Injection, Fast-Acting …
Matched Products: … Insulin Aspart Protamine and Insulin Aspart Mix 70/30 ... .Insulin Aspart Protamine and Insulin Aspart …
Cupric sulfate is a salt created by treating cupric oxide with sulfuric acid. This forms as large, bright blue crystals containing five molecules of water (CuSO4∙5H2O) and is also known as blue vitriol. The anhydrous salt is created by heating the hydrate to 150 °C (300 °F). Cupric sulfate is...
Approved
Matched Synonyms: … Cupric sulfate anhydrous ... Cupric sulfate, anhydrous ... Cupric sulphate anhydrous
Matched Name: … Cupric sulfate
Matched Iupac: … copper(2+) sulfate
Matched Description: … Cupric sulfate is a salt created by treating cupric oxide with sulfuric acid. ... After zinc and iron, copper is the third most abundant trace element found in the human body. ... Cupric sulfate is used primarily for agricultural purposes, as a pesticide, germicide, feed additive, …
Matched Mixtures name: … Stress B Complex With C,e, Zinc and Copper ... Stress Tab With Zinc, Copper and Vitamin E ... Multivitamins and Minerals Tablets …
Matched Salts name: … Cupric sulfate pentahydrate …
Matched Categories: … Sulfur Acids ... Sulfuric Acids ... Sulfates ... copper sulfate
Matched Products: … Cupric Sulfate
Mucor circinelloides f. lusitanicus allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, mucor circinelloides f. lusitanicus …
Investigational
Matched Synonyms: … antibody-drug conjugate comprised of a human aglycosylated anti-CD74 IgG1 antibody (SP7219) and two non-cleavable …
PRGN-3006 are autologous CD3+ T cells genetically modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and a truncated form of human HER1T (kill switch) on the cell surface.
Investigational
Matched Synonyms: … genetically modified using a non-viral system to express a CD33 CAR, membrane bound Interleukin-15, and
Matched Description: … genetically modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and
Investigational
Matched Synonyms: … recombinant adeno-associated viral (AAV) vector that contains a bio-engineered capsid (AAV-Spark100) and ... a codon-optimized expression cassette to drive expression of a secretable form of human acid a-glucosidase …
Atidarsagene autotemcel, sold under the brand name Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene. Libmeldy was granted orphan designation by the EMA in April 2007, and was...
Approved
Matched Synonyms: … Autologous CD34+ cell enriched population that contains haematopoietic stem and progenitor cells (HSPC ... deoxyribonucleic acid sequence ... Autologous CD34+ cells transduced with lentiviral vector which encodes for the aryl Sulfatase A complimentary …
Matched Description: … Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and ... [L45191] Libmeldy was granted orphan designation by the EMA in April 2007, and was issued a marketing …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Investigational
Matched Synonyms: … , mixture of three isomers a, b and c (25%, 50%, 25%) ... 4,4'-(15,20-diphenyl-7,8(or 12,13 or 17,18)-dihydro-21h,23h-porphine-5,10-diyl)bisbenzenesulfonic acid ... Benzenesulfonic acid, 4,4'-(7,8(or 17,18)-dihydro-10,15(or 15,20)-diphenyl-21h,23h-porphine-5,20(or 5,10 …
Approved
Investigational
Matched Synonyms: … Aluminum acetate
Matched Name: … Aluminum acetate
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
Matched Products: … ACID MANTLECREMA ... ACID MANTLE NLOCION ... ACID MANTLE N LOCION …
Titanium dioxide, also known as titanium(IV) oxide or titania, is the naturally occurring oxide of titanium. It is used as a pigment under the names titanium white, Pigment White 6 (PW6), or CI 77891. It is typically extracted from ilmenite, rutile and anatase.
Approved
Matched Description: … It is typically extracted from ilmenite, rutile and anatase. ... Titanium dioxide, also known as titanium(IV) oxide or titania, is the naturally occurring oxide of titanium …
Matched Mixtures name: … Zinc Oxide ... Zinc Oxide ... Zinc Oxide
Matched Categories: … Astringents and Deodorants …
Matched Products: … Revitalizing Alpha Hydroxy Make-UP - Cream ... Quick and Clean Oil Free Sun Spf35 Pa ... Super Bb Anti Wrinkle and Sun Protection Spf36 …
Demplatin pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and Gemcitabine Versus Gemcitabine Alone in Pancreatic Cancer).
Investigational
Matched Synonyms: … A micelle drug formulation composed of cisplatin and mPEG-poly(l-Glu) diblock copolymer with 1,3-propanediyl …
Matched Description: … pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Amino Acids, Dicarboxylic …
evorpacept is under investigation in clinical trial NCT04755244 (A Study of Evorpacept (ALX148) With Venetoclax and Azacitidine for Acute Myeloid Leukemia (ASPEN-05)).
Investigational
Matched Synonyms: … (SIRPalpha) variant 1 (v1) genetically linked to a modified and inactive Fc domain of human IgG ... , fusion protein containing a high affinity engineered D1 domain of human signal regulatory protein alpha
Matched Description: … is under investigation in clinical trial NCT04755244 (A Study of Evorpacept (ALX148) With Venetoclax and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 276 - 300 of 3330 in total