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Displaying drugs 401 - 425 of 14945 in total
Meningococcal group W-135 polysaccharide is group-specific polysaccharide antigens extracted and purified from Neisseria meningitidis serogroup W-135. N. meningitidis is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia. It is subcutaneously administered as an active immunization against the invasive meningococcal disease caused by the serogroup W-135.
Approved
Experimental
Investigational
Matched Description: … *N. meningitidis* is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia ... Meningococcal group W-135 polysaccharide is group-specific polysaccharide antigens extracted and purified …
Matched Mixtures name: … Menveo Powder and Solution for Solution for Injection ... NIMENRIX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... Nimenrix Powder and Solvent for Solution for Injection …
Bretylium blocks the release of noradrenaline from the peripheral sympathetic nervous system, and is used in emergency medicine, cardiology, and other specialties for the acute management of ventricular tachycardia and ventricular fibrillation. The primary mode of action for bretylium is thought to be inhibition of voltage-gated K(+) channels. Recent evidence...
Approved
Matched Description: … tachycardia and ventricular fibrillation. ... Bretylium blocks the release of noradrenaline from the peripheral sympathetic nervous system, and is ... used in emergency medicine, cardiology, and other specialties for the acute management of ventricular …
Matched Mixtures name: … Bretylium Tosylate 0.4% and Dextrose 5% Inj ... Bretylium Tosylate 0.2% and Dextrose 5% Inj …
Ammonia is a naturally-occurring compound with a chemical formula NH3 and structure of trigonal pyramidal geometry. It is a colorless gas with a pungent smell, and become NH4, or ammonium ion, when in water. Although ammonia is used as a food additive in the anhydrous form and serves as a...
Approved
Matched Description: … normally present in all tissues constituting a metabolic pool, where it is mostly taken up by glutamic acid ... pharmaceutical and commercial products, it is caustic and hazardous when concentrated. ... and take part in transamination and other reactions, including the synthesis of protein by the Krebs-Hanseleit …
Matched Mixtures name: … Physician EZ Use Joint Tunnel and Trigger Kit ... CVS Health Medication and Topical Refill Pouch ... JTT Physicians Joint, Tunnel and Trigger …
Acemetacin is a carboxymethyl ester of indometacin. It is a potent non-steroidal anti-inflammatory drug, derived from the indol-3-acetic acid, whose activity is thought to be mainly through its active metabolite indomethacin. In clinical trials, acemetacin exhibits a better gastric tolerability compared to its active metabolite indometacin. It was developed by...
Approved
Investigational
Matched Iupac: … 2-({2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetyl}oxy)acetic acid
Matched Description: … It is a potent non-steroidal anti-inflammatory drug, derived from the indol-3-acetic acid, whose activity ... Merck and Company in Germany as an attempt to provide a safer drug but other than the amelioration on ... the gastrointestinal effects, the metabolism of acetamicin led to the formation of indomethacin and
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Mitomycin is an antineoplastic antibiotic first isolated by Japanese microbiologists in the 1950s from cultures of Streptomyces caespitosus.[L12867,A193419] It is an alkylating agent that inhibits DNA synthesis (and, at higher concentrations, RNA and protein synthesis) by cross-linking the complementary strands of the DNA double helix. Few other antibiotics have been...
Approved
Matched Description: … , RNA and protein synthesis) by cross-linking the complementary strands of the DNA double helix. ... [L12867,A193419] It is an alkylating agent that inhibits DNA synthesis (and, at higher concentrations …
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... Indicators and Reagents ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Phleum pratense pollen allergenic extract is used in allergenic testing.
Approved
Investigational
Matched Mixtures name: … K-O-R-T and Sweet Vernal Standardized Grass Pollen Mix ... K-O-R-T and Sweet Vernal Standardized Grass Pollen Mix ... Mixture of Standardized and Non-Standardized Inland Grasses …
A flavonol glycoside found in many plants, including buckwheat; tobacco; forsythia; hydrangea; viola, etc. It has been used therapeutically to decrease capillary fragility.
Approved
Experimental
Investigational
Matched Mixtures name: … KORDEL`S C TIME ACID FREE C 1000MG TABLET …
Poa pratensis pollen is the pollen of the Poa pratensis plant. Poa pratensis pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … K-O-R-T and Sweet Vernal Standardized Grass Pollen Mix ... K-O-R-T and Sweet Vernal Standardized Grass Pollen Mix ... Mixture of Standardized and Non-Standardized Inland Grasses …
Meningococcal group A polysaccharide is group-specific polysaccharide antigens extracted and purified from Neisseria meningitidis serogroup A. N. meningitidis is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia. It is subcutaneously administered as an active immunization against the invasive meningococcal disease caused by the serogroup A.
Approved
Experimental
Investigational
Matched Description: … *N. meningitidis* is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia ... Meningococcal group A polysaccharide is group-specific polysaccharide antigens extracted and purified …
Matched Mixtures name: … Menveo Powder and Solution for Solution for Injection ... NIMENRIX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... Nimenrix Powder and Solvent for Solution for Injection …
Polyethylene glycol 300 (PEG 300) is a water-miscible polyether with an average molecular weight of 300 g/mol. It is a clear viscous liquid at room temperature with non-volatile, stable properties . Polyethylene glycols are widely used in biochemistry, structural biology, and medicine in addition to pharmaceutical and chemical industries. They...
Approved
Matched Description: … pharmaceutical and chemical industries. ... They serve as solubilizers, excipients, lubricants, and chemical reagents. ... Polyethylene glycols are widely used in biochemistry, structural biology, and medicine in addition to …
Matched Mixtures name: … Lubricant and Redness Reliever …
Casirivimab is a monoclonal antibody combined with Imdevimab in Regeneron's antibody cocktail known as REGN-COV2 for the treatment of COVID-19. This drug is a combination of antibodies derived from humanized VelocImmune® mice in addition to blood samples from patients who have recovered from COVID-19. These antibodies have been formulated to...
Approved
Experimental
Matched Description: … [L39130,L39135] Full safety and efficacy data are not yet available, and further evaluation of this ... Casirivimab and imdevimab are investigational recombinant human IgG1 monoclonal antibodies that, at this ... authorized emergency approval of REGEN-COV2 to treat mild to moderate COVID-19 in patients aged 12 years and
Matched Mixtures name: … Casirivimab and Imdevimab ... Casirivimab and Imdevimab …
Matched Categories: … casirivimab and imdevimab ... Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins …
Domiphen bromide is a quaternary ammonium compound that is predominantly employed as a topically administered antiseptic agent.
Approved
Experimental
Matched Mixtures name: … Mouthwash and Gargle ... Lander Orl Hygienic Mwh and Gargle …
Matched Categories: … Alimentary Tract and Metabolism ... Antiinfectives and Antiseptics for Local Oral Treatment …
Approved
Matched Mixtures name: … DENGVAXIA MD, POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION ... DENGVAXIA, POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION …
Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used in conjunction with diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus[FDA label,A2260,A2255,A2256]. The effect of this medication leads to glucose dependent increases in insulin and decreases in glucagon to improve control of blood sugar[FDA label,A2255]....
Approved
Investigational
Matched Description: … Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used in conjunction with diet and exercise ... The effect of this medication leads to glucose dependent increases in insulin and decreases in glucagon …
Matched Mixtures name: … Sitagliptin and metformin hydrochloride ... Sitagliptin and metformin hydrochloride ... Sitagliptin and metformin hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and sitagliptin ... sitagliptin and simvastatin ... pioglitazone and sitagliptin ... sitagliptin and ertugliflozin …
A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the thymidylate synthetase conversion of deoxyuridylic acid to thymidylic acid.
Approved
Matched Description: … to thymidylic acid. ... It interferes with DNA synthesis by blocking the thymidylate synthetase conversion of deoxyuridylic acid
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... Fluorouracil and prodrugs ... Skin and Mucous Membrane Agents ... Antineoplastic and Immunomodulating Agents …
Cefiderocol is a cephalosporin antibacterial drug and exerts a mechanism of action similar to other β-lactam antibiotics.[FDA Label] Unlike other agents in this category, cefiderocol is a siderophore able to undergo active transport into the bacterial cell through iron channels. It represents a significant addition to antibacterial treatment option as...
Approved
Investigational
Matched Description: … Cefiderocol is a cephalosporin antibacterial drug and exerts a mechanism of action similar to other β-lactam ... Cefiderocol was granted designation as a Qualified Infectious Disease Product and granted priority review ... effective *in vitro* against multidrug resistant strains including extended spectrum β-lactamase producers and
Matched Salts name: … Cefiderocol sulfate tosylate …
Hops allergenic extract is used in allergenic testing.
Approved
Matched Mixtures name: … Valerian and Hops Tablets ... Sanhelios Valerian Pearls and Hops …
Matched Categories: … Herbs and Natural Products …
A nonclassical folic acid inhibitor through its inhibition of the enzyme dihydrofolate reductase. It is being tested for efficacy as an antineoplastic agent and as an antiparasitic agent against pneumocystis pneumonia in AIDS patients. Myelosuppression is its dose-limiting toxic effect.
Approved
Investigational
Matched Description: … A nonclassical folic acid inhibitor through its inhibition of the enzyme dihydrofolate reductase. ... It is being tested for efficacy as an antineoplastic agent and as an antiparasitic agent against pneumocystis …
Matched Categories: … Folic Acid Antagonists ... Antiparasitic Products, Insecticides and Repellents …
Hexylcaine hydrochloride is also known as cyclaine and osmocaine. It is a short acting local anesthetic that acts through inhibition of sodium channels. Patients experience an overdose may present with headache, tinnitus, numbness and tingling around the mouth and tongue, convulsions, inability to breathe, and decreased heart function. Hexylcaine has...
Approved
Withdrawn
Matched Description: … mouth and tongue, convulsions, inability to breathe, and decreased heart function. ... Hexylcaine hydrochloride is also known as cyclaine and osmocaine. ... Patients experience an overdose may present with headache, tinnitus, numbness and tingling around the …
Romosozumab is a humanized monoclonal antibody indicated for the treatment of osteoperosis in postmenopausal women at high risk of fracture and patients who have failed in other treatments or are intolerant to other osteoperosis therapies . Romosozumab prevents bone resorption and induces the formation of bone though it is associated...
Approved
Investigational
Matched Description: … 12 months followed by alendronic acid for 12 months was superior to alendronic acid alone for 24 months ... increased risk of cardiac death, heart attack, and stroke in one study[L5921,L5924]. ... antibody indicated for the treatment of osteoperosis in postmenopausal women at high risk of fracture and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Drugs Affecting Bone Structure and Mineralization …
A long acting sulfonamide that is used, usually in combination with other drugs, for respiratory, urinary tract, and malarial infections.
Approved
Investigational
Matched Description: … sulfonamide that is used, usually in combination with other drugs, for respiratory, urinary tract, and
Matched Categories: … Genito Urinary System and Sex Hormones ... artesunate, sulfadoxine and pyrimethamine ... Gynecological Antiinfectives and Antiseptics ... Antiparasitic Products, Insecticides and Repellents …
Ammonium chloride is an inorganic compound with the formula NH4Cl. It is highly soluble in water producing mildly acidic solutions.
Approved
Investigational
Vet approved
Matched Mixtures name: … Cough and Allergy Syrup With Codeine …
Matched Categories: … Blood and Blood Forming Organs ... Genito Urinary System and Sex Hormones ... Blood Substitutes and Perfusion Solutions …
A methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. Theophylline is marketed under several brand names such as Uniphyl and Theochron, and it is indicated mainly...
Approved
Matched Description: … Theophylline is marketed under several brand names such as Uniphyl and Theochron, and it is indicated ... mainly for asthma, bronchospasm, and COPD. ... methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and
Matched Mixtures name: … Theophylline 4mg and 5% Dextrose Inj ... Theophylline 1.6mg and 5% Dextrose Inj ... Theophylline 0.8mg and 5% Dextrose Inj …
Matched Categories: … Xanthines and Adrenergics ... theophylline and adrenergics …
Clonidine is an imidazole derivate that acts as an agonist of alpha-2 adrenoceptors. This activity is useful for the treatment of hypertension, severe pain, and ADHD.[L7237,L7240,L7243,L7246] Clonidine was granted FDA approval on 3 September 1974.
Approved
Matched Description: … [A180559] This activity is useful for the treatment of hypertension, severe pain, and ADHD. …
Matched Categories: … clonidine and diuretics ... Antiglaucoma Preparations and Miotics ... clonidine and diuretics, combinations with other drugs …
A polyhydric alcohol with about half the sweetness of sucrose. Sorbitol occurs naturally and is also produced synthetically from glucose. It was formerly used as a diuretic and may still be used as a laxative and in irrigating solutions for some surgical procedures.
Approved
Matched Description: … It was formerly used as a diuretic and may still be used as a laxative and in irrigating solutions for ... Sorbitol occurs naturally and is also produced synthetically from glucose. …
Matched Mixtures name: … Cleanse Gut And Colon ... INFUSOL M20S (Mannitol 17.5%w/v and Sorbitol 2.5%w/v Intravenous Infusion) …
Matched Categories: … Indicators and Reagents ... Diet, Food, and Nutrition ... Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Displaying drugs 401 - 425 of 14945 in total