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Displaying drugs 626 - 650 of 794 in total

Ketotifen

Ketotifen is a benzocycloheptathiophene derivative with potent antihistaminic and mast cell stabilizing properties. It has a similar structure to some other first-generation antihistamines such as cyproheptadine and azatadine. Ketotifen was first developed in Switzerland in 1970 by Sandoz Pharmaceuticals and was initially marketed for the treatment of anaphylaxis. In the...
Approved
Matched Description: … allergic symptoms and disorders,[A231204] including urticaria, mastocytosis, and food allergy. ... Ketotifen is a benzocycloheptathiophene derivative[A231204] with potent antihistaminic and mast cell ... It has a similar structure to some other first-generation antihistamines such as [cyproheptadine] and …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Up and Up Eye Itch Relief …

Esmolol

Esmolol, commonly marketed under the trade name Brevibloc, is a cardioselective beta-1 receptor blocker. It has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses. It works by blocking beta-adrenergic receptors in the heart, which leads to decreased...
Approved
Withdrawn
Matched Description: … It works by blocking beta-adrenergic receptors in the heart, which leads to decreased force and rate ... Esmolol prevents the action of two naturally occurring substances: epinephrine and norepinephrine. ... FDA withdrew its approval for the use of all parenteral dosage form drug products containing esmolol hydrochloride …
Matched Salts name: … Esmolol hydrochloride …
Matched Products: … Esmolol Hydrochloride ... Esmolol Hydrochloride in Water ... Esmolol Hydrochloride In Sodium Chloride …

(2R)-2-Acetamido-3-(octadecyloxy)propyl 2-(methylsulfanyl)ethyl hydrogen phosphate

Experimental
Matched Synonyms: … 1-Octadecyl-2-acetamido-2-deoxy-SN-glycerol-3-phosphoethylmethyl sulfide …

Cholecalciferol

Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight . Both the endogenous form of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin D3 (cholecalciferol), and the plant-derived form, vitamin D2 (ergocalciferol), are...
Approved
Nutraceutical
Matched Description: … C23 and has an additional methyl group at C24 [L5689]. ... of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin D3 (cholecalciferol), and ... the plant-derived form, vitamin D2 (ergocalciferol), are considered the main forms of vitamin d and …
Matched Mixtures name: … PR Natal 400 ... PR Natal 400 ec ... Duet DHA 400 …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition ... Calcium-Regulating Hormones and Agents ... Vitamin D and Analogues ... ibandronic acid and colecalciferol …
Matched Products: … DECAL® 7000 UI ... DEFEROL ® 7000 UI ... FARMA D® 7000 UI …

Mosedipimod

Mosedipimod has been used in trials studying the supportive care and treatment of Chemotherapy-induced Neutropenia.
Investigational
Matched Synonyms: … 1-Palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol …
Matched Description: … Mosedipimod has been used in trials studying the supportive care and treatment of Chemotherapy-induced …

Terazosin

Terazosin is a quinazoline derivative alpha-1-selective adrenergic blocking agent indicated for benign prostatic hyperplasia and hypertension[FDA Label] . Terazosin blocks adrenaline's action on alpha-1 adrenergic receptors, causing relaxation of smooth muscle in blood vessels and the prostate .
Approved
Matched Description: … quinazoline derivative alpha-1-selective adrenergic blocking agent indicated for benign prostatic hyperplasia and ... adrenaline's action on alpha-1 adrenergic receptors, causing relaxation of smooth muscle in blood vessels and …
Matched Salts name: … Terazosin hydrochloride ... Terazosin hydrochloride hydrate …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … Terazosin Hydrochloride ... Terazosin hydrochloride ... Terazosin Hydrochloride Anhydrous …

1,4-Dioxane

Experimental
Matched Synonyms: … glycol ethylene ether …

Iodide I-131

Iodide I-131 (as Sodium iodide I-131) is a radioisotopic drug used for the treatment and palliation of thyroid malignancy. Iodine-131 is notable for causing mutation and death in cells that it penetrates, which is due to its mode of beta decay. As a result of beta decay, approximately 10% of...
Approved
Investigational
Matched Description: … Iodide I-131 (as Sodium iodide I-131) is a radioisotopic drug used for the treatment and palliation of ... Iodine-131 is notable for causing mutation and death in cells that it penetrates, which is due to its ... As a result of beta decay, approximately 10% of its energy and radiation dose is via gamma radiation, …
Matched Products: … MON.IYOT-131 74-18500 MBQ ORAL ÇÖZELTİ İÇEREN FLAKON, 400 MCİ ... MON.IYOT-131 0.37-7400 MBQ (10µ Cİ-200 M Cİ) ORAL KAPSÜL, 70 MCİ …

Triprolidine

First generation histamine H1 antagonist used in allergic rhinitis; asthma; and urticaria. It is a component of cough and cold medicines. It may cause drowsiness.
Approved
Matched Description: … It is a component of cough and cold medicines. It may cause drowsiness. ... First generation histamine H1 antagonist used in allergic rhinitis; asthma; and urticaria. …
Matched Salts cas: … 550-70-9 …
Matched Mixtures name: … Mucinex Nightshift Cold and Flu Clear and Cool ... Mucus Relief DM and Overnight Cold and Flu ... and Flu Clear and Cool …
Matched Salts name: … Triprolidine hydrochloride ... Triprolidine hydrochloride monohydrate …
Matched Products: … Triprolidine Hydrochloride …

Ursodeoxycholic acid

Ursodeoxycholic acid (UDCA), also known as ursodiol, is a naturally-occurring bile acid that constitutes a minor fraction of the human bile acid pool.[A256272,A256277] UDCA has been used to treat liver disease for decades: its first use in traditional medicine dates back more than a hundred years.[A256267,A256463] UDCA was first characterized...
Approved
Investigational
Matched Description: … [A256267,A256463] UDCA was first characterized in the bile of the Chinese black bear and is formed by ... [A256272] UDCA was first approved by the FDA in 1987 for dissolution of gallstones and for primary …
Matched Categories: … Bile Acids and Salts ... Alimentary Tract and Metabolism ... Bile and Liver Therapy ... Bile acids and derivatives ... Cholagogues and Choleretics …
Matched Products: … Reltone 400 mg ... Ursodiol 400 mg ... URSO 400 HEUMANN …

Chloroprocaine

Chloroprocaine is an ester local anesthetic commonly available in its salt form, chloroprocaine hydrochloride. Similar to other local anesthetics, it increases the threshold for electrical excitation in nerves by slowing the propagation of the nerve impulse and reducing the rate of rise of the action potential. The pharmacological profile of...
Approved
Investigational
Matched Description: … Chloroprocaine is an ester local anesthetic commonly available in its salt form, chloroprocaine hydrochloride ... [A252952] Chloroprocaine can be given as an injection, and is available in formulations with and without ... formulation can be used for lumbar and caudal epidural blocks. …
Matched Salts name: … Chloroprocaine hydrochloride …
Matched Products: … Chloroprocaine Hydrochloride …

Minocycline

Minocycline was first described in the literacture in 1966. It is a second generation tetracycline antibiotic that is active against gram-negative and gram-positive bacteria. Like other semisynthetic tetracyclines, minocycline has modifications to carbons 7-9 on the D ring to generate higher efficacy than previous tetracyclines. Minocycline was granted FDA approval...
Approved
Investigational
Matched Description: … [A190681] It is a second generation tetracycline antibiotic that is active against gram-negative and …
Matched Salts name: … Minocycline hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... Antiinfectives and Antiseptics for Local Oral Treatment …
Matched Products: … Minocycline Hydrochloride ... Minocycline hydrochloride …

Cyproheptadine

Cyproheptadine is a potent competitive antagonist of both serotonin and histamine receptors. It is used primarily to treat allergic symptoms, though it is perhaps more notable for its use in appetite stimulation and its off-label use in the treatment of serotonin syndrome.
Approved
Matched Description: … Cyproheptadine is a potent competitive antagonist of both serotonin and histamine receptors. ... treat allergic symptoms, though it is perhaps more notable for its use in appetite stimulation[L32519] and …
Matched Salts name: … Cyproheptadine hydrochloride …
Matched Products: … Cyproheptadine Hydrochloride ... CYPROHEPTADINE HYDROCHLORIDE ... CYPROHEPTADINE HYDROCHLORIDE SYRUP …

Loxapine

An antipsychotic agent used in schizophrenia. [PubChem]
Approved
Matched Salts name: … Loxapine hydrochloride …
Matched Categories: … Diazepines, Oxazepines, Thiazepines and Oxepines …
Matched Products: … Loxapine Hydrochloride Im Injection 50mg/ml ... Loxapine Hydrochloride Oral Concentrate 25mg/ml …

Oxybuprocaine

Oxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology and otolaryngology. Oxybuprocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions.
Approved
Investigational
Matched Description: … Oxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology and ... Oxybuprocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases …
Matched Mixtures name: … Fluorescein Sodium and Benoxinate Hydrochloride ... Fluorescein Sodium and Benoxinate Hydrochloride ... Fluorescein Sodium and Benoxinate Hydrochloride …
Matched Salts name: … Oxybuprocaine hydrochloride …
Matched Products: … Minims Benoxinate Hydrochloride 0.4% …

NNZ-2591

NNZ-2591 (cyclo-L-glycyl-L-2-allylproline) is an investigational synthetic analog of cyclic glycine-proline (cGP), a breakdown product of human insulin-like growth factor 1 (IGF-1), that has been chemically modified to increase its half-life, stability, and oral bioavailability. It is currently under development by Neuren Pharmaceuticals for the symptomatic treatment of Angelman, Phelan-McDermid, and...
Investigational
Matched Synonyms: … Cyclo(-L-glycyl-L-2-allylproline) …
Matched Description: … It was granted Orphan Drug Designation by the FDA in October 2019[L11103] and was granted a patent by ... NNZ-2591 (cyclo-L-glycyl-L-2-allylproline)[A189390] is an investigational synthetic analog of cyclic ... under development by Neuren Pharmaceuticals for the symptomatic treatment of Angelman, Phelan-McDermid, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Trifluoperazine

A phenothiazine with actions similar to chlorpromazine. It is used as an antipsychotic and an antiemetic.
Approved
Investigational
Matched Description: … It is used as an antipsychotic and an antiemetic. …
Matched Salts name: … Trifluoperazine hydrochloride …
Matched Products: … Trifluoperazine Hydrochloride ... TRIFLUOPERAZINE HYDROCHLORIDE …

Triheptanoin

Triheptanoin is a source of heptanoate fatty acids, which can be metabolized without the enzymes of long chain fatty acid oxidation. In clinical trials, patients with long chain fatty acid oxidation disorders (lc-FAODs) treated with triheptanoin are less likely to develop hypoglycemia, cardiomyopathy, rhabdomyolysis, and hepatomegaly.[A214812,A214817] Complications in lc-FAOD patients...
Approved
Investigational
Matched Synonyms: … Glycerol triheptanoate …
Matched Description: … treated with triheptanoin are less likely to develop hypoglycemia, cardiomyopathy, rhabdomyolysis, and …
Matched Categories: … Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products …

PVX-410 component CD138 260-268(GLVGLIFAV)

Investigational
Matched Synonyms: … L-valine, glycyl-l-leucyl-l-valylglycyl-l-leucyl-l-isoleucyl-l-phenylalanyl-l-alanyl- …

Progesterone

Progesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity, embryo implantation, and the successful establishment of pregnancy. A low progesterone concentration or an insufficient response to progesterone can cause infertility and pregnancy loss . Progesterone is used in various contraceptive preparations to prevent ovulation...
Approved
Vet approved
Matched Description: … , embryo implantation, and the successful establishment of pregnancy. ... ], [A175612] as well as in other formulations to promote and support pregnancy. ... Progesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity …
Matched Mixtures name: … Estradiol and Progesterone …
Matched Categories: … progesterone and estrogen ... Progesterone and Derivatives ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … CYCLOGEST 400 ... PROGENDO 400 MG ... CYCLOGEST PESSARY 400 mg …

Diltiazem

Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. Approved in 1982 by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug class. It works through various mechanisms of action, but it primarily works by inhibiting the calcium influx into cardiac and vascular smooth muscle...
Approved
Investigational
Matched Description: … Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. ... under various brand names with Cardizem and Tiazac being the most common ones. ... various mechanisms of action, but it primarily works by inhibiting the calcium influx into cardiac and …
Matched Salts name: … Diltiazem hydrochloride …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Diltiazem Hydrochloride ... Diltiazem hydrochloride ... DILTIAZEM HYDROCHLORIDE …

Choline alfoscerate

A component of phosphatidylcholines (lecithins), in which the two hydroxy groups of glycerol are esterified with fatty acids. (From Stedman, 26th ed) It counteracts the effects of urea on enzymes and other macromolecules. [PubChem]
Experimental
Investigational
Matched Synonyms: … glycerol-3-phosphocholine ... Glycerol phosphorylcholine ... Glycerol-3-phosphatidylcholine …
Matched Description: … (From Stedman, 26th ed) It counteracts the effects of urea on enzymes and other macromolecules. ... A component of phosphatidylcholines (lecithins), in which the two hydroxy groups of glycerol are esterified …

Nalbuphine

A narcotic used as a pain medication. It appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid receptors. Nalbuphine is the only opioid analgesic that is not a controlled substance in the United States.
Approved
Matched Description: … It appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid …
Matched Salts name: … Nalbuphine hydrochloride …
Matched Products: … Nalbuphine Hydrochloride …

Digalactosyl Diacyl Glycerol (Dgdg)

Experimental
Matched Name: … Digalactosyl Diacyl Glycerol (Dgdg) …

Tramadol

Tramadol is a centrally acting synthetic opioid analgesic and SNRI (serotonin/norepinephrine reuptake-inhibitor) that is structurally related to codeine and morphine. Due to its good tolerability profile and multimodal mechanism of action, tramadol is generally considered a lower-risk opioid option for the treatment of moderate to severe pain. It is considered...
Approved
Investigational
Matched Description: … of and response to pain. ... such as [duloxetine] and [venlafaxine]. ... ) that is structurally related to [codeine] and [morphine]. …
Matched Mixtures name: … Tramadol Hydrochloride and Acetaminophen ... Tramadol Hydrochloride and Acetaminophen ... Tramadol Hydrochloride and Acetaminophen …
Matched Salts name: … Tramadol hydrochloride …
Matched Categories: … tramadol and celecoxib ... tramadol and paracetamol ... tramadol and dexketoprofen …
Matched Products: … TRAVEX ONE 400MG ... TRAMACONTIN ® 400 MG COMPRIMIDOS DE LIBERACION PROLONGADA ... Tramadol Hydrochloride …
Displaying drugs 626 - 650 of 794 in total