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Displaying drugs 801 - 825 of 880 in total
Experimental
Matched Synonyms: … Dihydrogen sulfate
Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)
Approved
Investigational
Nutraceutical
Matched International brands: … Sam-Sulfate
Matched Description: … Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all ... It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids and Derivatives ... Amino Acids, Peptides, and Proteins ... Nucleic Acids, Nucleotides, and Nucleosides …
Atorvastatin (Lipitor®), is a lipid-lowering drug included in the statin class of medications. By inhibiting the endogenous production of cholesterol in the liver, statins lower abnormal cholesterol and lipid levels, and ultimately reduce the risk of cardiovascular disease. More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,...
Approved
Matched Description: … lipid levels, and ultimately reduce the risk of cardiovascular disease. ... inhibiting the endogenous production of cholesterol in the liver, statins lower abnormal cholesterol and ... Bruce Roth and approved by the FDA in 1996. …
Matched Mixtures name: … Amlodipine Besylate and Atorvastatin Calcium ... Amlodipine Besylate and Atorvastatin Calcium ... Amlodipine Besylate and Atorvastatin Calcium
Matched Salts name: … Atorvastatin calcium ... Atorvastatin calcium trihydrate …
Matched Categories: … atorvastatin and ezetimibe ... atorvastatin and amlodipine ... atorvastatin and perindopril ... atorvastatin, amlodipine and ramipril ... atorvastatin, amlodipine and perindopril …
Matched Products: … Atorvastatin Calcium ... Atorvastatin calcium ... ATORVASTATIN CALCIUM
Synthetic guanethidine derivative that locates phaeochromocytomas and neuroblastomas. The radioisotope used can either be iodine-123 for imaging or iodine-131 for destruction of tissues that metabolize noradrenaline. Iodine 123 is a cyclotron-produced radionuclide that decays to Te 123 by electron capture. Images are produced by a I123 MIBG scintigraphy. FDA approved...
Approved
Investigational
Matched Description: … Synthetic guanethidine derivative that locates phaeochromocytomas and neuroblastomas. …
Matched Salts name: … Iobenguane sulfate ... Iobenguane sulfate I 123 ... Iobenguane sulfate I 131 …
Matched Categories: … Indicators and Reagents …
Matched Products: … Iobenguane Sulfate I 131 Injection …
Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.
Approved
Vet approved
Matched Description: … Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antiinflammatory and Antirheumatic Products ... Ketoprofen and isomer ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain …
Matched Products: … OKI GOLA ... KELIS GOLA ... EUSPIDOL GOLA
SEP-363856 is a novel psychotropic drug being investigated for the treatment of schizophrenia. Unlike other drugs used for this condition, SEP-363856 does not bind to the dopamine D2 receptors, but exerts actions on the trace amine–associated receptor 1 (TAAR1) and 5-hydroxytryptamine type 1A (5-HT1A). SEP-363856 was developed by Sunovion pharmaceuticals....
Investigational
Matched Name: … SEP-363856 …
Matched Description: … Additional clinical trials of SEP-363856 are required to confirm the safety and efficacy of this drug ... , and social withdrawal. ... exerts actions on the trace amine–associated receptor 1 (TAAR1) and 5-hydroxytryptamine type 1A (5-HT1A …
MK-4541 is a 4-azasteroid and a selective androgen receptor modulator (SARM). MK-4541 acts as a dual selective SARM and is both a potent androgen receptor antagonist and a 5α-reductase inhibitor.
Investigational
Matched Synonyms: … 9bS,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,9b,10,11-decahydro-1H-indeno[5,4-f]quinolin-1-yl]carbamate
Matched Description: … MK-4541 acts as a dual selective SARM and is both a potent androgen receptor antagonist and a 5α-reductase ... MK-4541 is a 4-azasteroid and a selective androgen receptor modulator (SARM). …
Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)1B/1D/(1F) receptor agonists used to treat acute migraine.[A462, L12978] Sumatriptan was the first triptan to be developed, but had poor oral bioavailability and lipophilicity. This led to the development of second-generation triptans, including almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, and zolmitriptan. Triptans...
Approved
Investigational
Matched Description: … A462, L12978] [Sumatriptan] was the first triptan to be developed, but had poor oral bioavailability and ... It is currently available in both tablet and nasal spray forms.[L12978] ... second-generation triptans, including [almotriptan], [eletriptan], [frovatriptan], [naratriptan], [rizatriptan], and
Matched Categories: … Serotonin-1b and Serotonin-1d Receptor Agonist …
Matched Products: … Septa-zolmitriptan-odt …
A benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)
Approved
Vet approved
Matched Synonyms: … O-methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate
Matched Iupac: … methyl N-[6-(propylsulfanyl)-1H-1,3-benzodiazol-2-yl]carbamate
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Bethanechol is a synthetic ester that was initially synthesized in 1935.[A232905,L32539] As a cholinergic agent, bethanechol is similar in structure and pharmacological function to acetylcholine and is used in specific cases when stimulation of the parasympathetic nervous system is necessary.[A232905,L32539] For example, bethanechol is readily used to treat postoperative or...
Approved
Matched Synonyms: … (2-hydroxypropyl)trimethylammonium carbamate
Matched Iupac: … 1-(trimethylazaniumyl)propan-2-yl carbamate
Matched Description: … [A232905,L32539] As a cholinergic agent, bethanechol is similar in structure and pharmacological function ... to acetylcholine and is used in specific cases when stimulation of the parasympathetic nervous system …
Idursulfase beta is under investigation in clinical trial NCT01645189 (Safety and Efficacy of Hunterase).
Investigational
Matched Synonyms: … Iduronate 2-sulfatase (a-l-iduronate sulfate sulfatase), human proenzyme produced in cho cells (glycoform …
Matched Description: … Idursulfase beta is under investigation in clinical trial NCT01645189 (Safety and Efficacy of Hunterase …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Zafirlukast is an oral leukotriene receptor antagonist (LTRA) for the maintenance treatment of asthma, often used in conjunction with an inhaled steroid and/or long-acting bronchodilator. It is available as a tablet and is usually dosed twice daily. Another leukotriene receptor antagonist is montelukast (Singulair), which is usually taken just once...
Approved
Investigational
Matched Synonyms: … cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carbamoyl)benzyl)-1-methylindole-5-carbamate
Matched Iupac: … cyclopentyl N-[3-({2-methoxy-4-[(2-methylbenzenesulfonyl)carbamoyl]phenyl}methyl)-1-methyl-1H-indol-5-yl]carbamate
Matched Description: … It is available as a tablet and is usually dosed twice daily. ... antagonist (LTRA) for the maintenance treatment of asthma, often used in conjunction with an inhaled steroid and ... on the CysLT1 receptors, thus reducing constriction of the airways, build-up of mucus in the lungs and
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Experimental
Matched Synonyms: … Golden shower fruit ... Golden shower tree fruit ... Golden shower cassia fruit …
Polyvinyl alcohol is a water-soluble synthetic polymer obtained by polymerization of vinyl alcohol. It has varying roles in commercial and industrial applications such as papermaking, textiles, and printing. Polyvinyl alcohol is found in ophthalmic solutions as a lubricant to prevent irritation or to relieve dryness of the eyes .
Approved
Matched Description: … It has varying roles in commercial and industrial applications such as papermaking, textiles, and printing …
Matched Mixtures name: … Clear Eyes Natural Tears ... Sound Body Artificial Tears …
Matched Products: … ALCOHOL POLIVINILICO OFTALMICO LAGRIMAS NATURALES OPHTHAVINIL …
Quinagolide is a non-ergot-derived selective dopamine D2 receptor agonist used for the treatment of elevated levels of prolactin or hyperprolactinaemia. Hyperprolalctinaemia is associated with gonadal dysfunction, including infertility and reduced libido, as well as long-term complications such as osteoporosis . Newer dopamine receptor agonists such as quinagolide and DB00248 are...
Approved
Investigational
Matched Synonyms: … N-Diethyl-N'-((3R*,4aR*,10aS*)-1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propylbenzo(g)quinolin-3-yl)sulfamide
Matched Description: … Hyperprolalctinaemia is associated with gonadal dysfunction, including infertility and reduced libido ... Newer dopamine receptor agonists such as quinagolide and [DB00248] are shown to effectively inhibit prolactin ... Quinagolide exists as a racemate and its relevant clinical activity is mediated predominantly by the …
Matched Categories: … Genito Urinary System and Sex Hormones …
Cobicistat, marketed under the name Tybost (formerly GS-9350), indicated for treating infection with human immunodeficiency virus (HIV). Although it does not have any anti-HIV activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting cytochrome P450 3A isoforms (CYP3A) and therefore increases the systemic exposure of coadministered agents that are metabolized...
Approved
Matched Synonyms: … thiazol-4-yl)methyl](methyl)carbamoyl}amino)-4-(morpholin-4-yl)butanoyl]amino}-1,6-diphenylhexan-2-yl]carbamate
Matched Iupac: … -yl)-1,3-thiazol-4-yl]methyl})carbamoyl]amino}-4-(morpholin-4-yl)butanamido]-1,6-diphenylhexan-2-yl]carbamate
Matched Description: … activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting cytochrome P450 3A isoforms (CYP3A) and ... exposure of anti-retrovirals (ARVs) without increasing dosage allows for better treatment outcomes and
Matched Categories: … darunavir and cobicistat ... atazanavir and cobicistat ... Metabolic Side Effects of Drugs and Substances ... emtricitabine, tenofovir alafenamide, darunavir and cobicistat ... emtricitabine, tenofovir disoproxil, elvitegravir and cobicistat …
Salbutamol (Albuterol [USAN]) is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. Salbutamol is formulated as a...
Approved
Vet approved
Matched Description: … USAN]) is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and ... Salbutamol is formulated as a racemic mixture of the R- and S-isomers. ... The R-isomer has 150 times greater affinity for the beta2-receptor than the S-isomer and the S-isomer …
Matched Mixtures name: … Ipratropium Bromide and Albuterol Sulfate ... Ipratropium Bromide and Albuterol Sulfate ... Ipratropium Bromide and Albuterol Sulfate
Matched Salts name: … Albuterol sulfate
Matched Categories: … salbutamol and beclometasone ... salbutamol and sodium cromoglicate ... salbutamol and ipratropium bromide …
Matched Products: … Albuterol Sulfate ... Albuterol sulfate ... Albuterol Sulfate ER …
Experimental
Matched Synonyms: … Iodopropynyl butyl carbamate
First synthesized by Janssen Pharmaceuticals in 1955, cinnarizine is an anti-histaminic drug mainly used for the control of vestibular disorders and motion sickness. Cinnarizine is a specific calcium channel blocker that primarily works on the central vestibular system to interfere with the signal transmission between vestibular apparatus of the inner...
Approved
Investigational
Matched International brands: … Sepan
Matched Description: … in 1955, cinnarizine is an anti-histaminic drug mainly used for the control of vestibular disorders and ... to interfere with the signal transmission between vestibular apparatus of the inner ear and the vomiting ... centre of the hypothalamus. …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Calcium Channel Blockers …
Experimental
Matched Name: … 3,6-Anhydro-2-(hydrogen sulfate)-alpha-D-galactopyranose …
Olmesartan belongs to the angiotensin II receptor blocker (ARB) family of drugs, which also includes telmisartan, candesartan, losartan, valsartan, and irbesartan. ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of aldosterone...
Approved
Investigational
Matched International brands: … Golme
Matched Description: … However, this does not prevent the formation of all angiotensin II within the body. ... and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of ... aldosterone and ADH, cardiac stimulation, and renal reabsorption of sodium, among others. …
Matched Mixtures name: … Amlodipine and olmesartan Medoxomil ... Amlodipine and olmesartan Medoxomil ... Amlodipine and olmesartan Medoxomil …
Matched Categories: … Angiotensin II Antagonists and Calcium Channel Blockers ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... Angiotensin II receptor blockers (ARBs) and diuretics ... olmesartan medoxomil and diuretics ... olmesartan medoxomil and amlodipine …
Rosuvastatin, also known as the brand name product Crestor, is a lipid-lowering drug that belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver. More specifically, statin medications...
Approved
Matched Description: … belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and ... of metabolic reactions involved in the production of several compounds involved in lipid metabolism and ... including cholesterol, low-density lipoprotein (LDL) (sometimes referred to as "bad cholesterol"), and
Matched Mixtures name: … Rosuvastatin and Ezetimibe ... Rosuvastatin and Ezetimibe ... Rosuvastatin and Ezetimibe …
Matched Salts name: … Rosuvastatin calcium
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... rosuvastatin and valsartan ... Gynecological Antiinfectives and Antiseptics ... rosuvastatin and ramipril …
Matched Products: … Rosuvastatin Calcium ... Rosuvastatin calcium ... ROSUVASTATIN CALCIUM
Amaranthus retroflexus whole allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Red-root amaranth whole …
Experimental
Matched Name: … TERT-BUTYL {2-[(1,3-THIAZOL-2-YLAMINO)CARBONYL]PYRIDIN-3-YL}CARBAMATE
Matched Iupac: … tert-butyl N-{2-[(1,3-thiazol-2-yl)carbamoyl]pyridin-3-yl}carbamate
Investigational
Matched Synonyms: … Sulindac sulfone
Displaying drugs 801 - 825 of 880 in total