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Displaying drugs 76 - 100 of 8517 in total
Tetracaine is an ester local anaesthetic currently available in combination with lidocaine as a cream and patch.
Approved
Vet approved
Matched Categories: … Esters of Aminobenzoic Acid ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis,...
Approved
Investigational
Matched Description: … a family of enzymes known as "penicillin-binding proteins" (PBPs). ... A232920] β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of ... glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of
Zoledronic acid, or CGP 42'446, is a third generation, nitrogen containing bisphosphonate similar to ibandronic acid, minodronic acid, and risedronic acid. Zoledronic acid is used to treat and prevent multiple forms of osteoporosis, hypercalcemia of malignancy, multiple myeloma, bone metastases from solid tumors, and Paget’s disease of bone.[L13712,L13715,L13721] Zoledronic acid...
Approved
Matched Description: … of malignancy, multiple myeloma, bone metastases from solid tumors, and Paget’s disease of bone. ... [A203111] Zoledronic acid is used to treat and prevent multiple forms of osteoporosis, hypercalcemia …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. It is marketed by Genzyme under the trade name Renagel.
Approved
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
Sodium phosphate is a saline laxative that is thought to work by increasing fluid in the small intestine. It usually results in a bowel movement after 30 minutes to 6 hours.
Approved
Matched Mixtures name: … TERUFLEX Blood Anticoagulant Citrate Phosphate Dextrose Adenine (CPDA-1) for Collection of 450mL of Blood …
Matched Categories: … Drugs for Treatment of Hypercalcemia …
Collagenase clostridium histolyticum is an enzyme produced by the bacterium Clostridium histolyticum. It is beneficial in the breakdown of collagen plaques for the treatment of Dupuytren's contracture and Peyronie's disease. The topical formulation is used for the debridement of necrotic tissue due to burns or chronic ulcers. On July 6,...
Approved
Investigational
Matched Description: … It is beneficial in the breakdown of collagen plaques for the treatment of Dupuytren's contracture and ... for the treatment of cellulite in adult women. ... [L14882] The topical formulation is used for the debridement of necrotic tissue due to burns or chronic …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers …
Ibandronate, or BM 21.0955, is a third generation, nitrogen containing bisphosphonate similar to zoledronic acid, minodronic acid, and risedronic acid.[A203111,A203138] It is used to prevent and treat postmenopausal osteoporosis.[L13805,L13808] Ibandronate was first described in the literature in 1993 as a treatment for bone loss in dogs. Ibandronate was granted FDA...
Approved
Investigational
Matched Categories: … Drugs for Treatment of Bone Diseases …
Benzylpenicilloyl polylysine is used as a skin-testing reagent to detect immunoglobulin E antibodies in people with a history of penicillin allergy. The quantitation of in vitro IgE antibodies to the benzylpenicilloyl determinant is a useful tool for evaluating allergic subjects.
Approved
Matched Description: … The quantitation of in vitro IgE antibodies to the benzylpenicilloyl determinant is a useful tool for ... polylysine is used as a skin-testing reagent to detect immunoglobulin E antibodies in people with a history of
Matched Categories: … combinations of penicillins …
A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with anemia, short stature, hypogonadism, impaired wound...
Approved
Investigational
Matched Description: … in the pathophysiology and treatment of affective disorders, plus discussed the potential value of zinc ... as a marker of these diseases [L2097]. ... A metallic element of atomic number 30 and atomic weight 65.38. …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Iron sucrose (sucroferric oxyhydroxide or iron saccharate) is used as a source of iron in patients with iron deficiency anemia with chronic kidney disease (CKD), including those who are undergoing dialysis (hemodialysis or peritoneal) and those who do not require dialysis. Due to less side effects than iron dextran, iron...
Approved
Matched Description: … Iron sucrose (sucroferric oxyhydroxide or iron saccharate) is used as a source of iron in patients with …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
Tyropanoic acid is a radiocontrast agent used in cholecystography, the X-ray diagnosis of gallstones under the trade names include Bilopaque, Lumopaque, Tyropaque, and Bilopac. The molecule contains three heavy iodine atoms which obstruct X-rays in the same way as the calcium in bones, which results in a visible image .
Approved
Matched Description: … Tyropanoic acid is a radiocontrast agent used in cholecystography, the X-ray diagnosis of gallstones …
Matched Categories: … Diagnostic Uses of Chemicals …
Zinc gluconate is a zinc salt of gluconic acid comprised of two gluconic acid molecules for each zinc cation (2+). Zinc gluconate is a generally recognized as safe (GRAS) substance by FDA . It is available as a trace mineral supplement and over the counter as a lozenge form for...
Approved
Vet approved
Matched Description: … Zinc gluconate is a zinc salt of gluconic acid comprised of two gluconic acid molecules for each zinc ... has been associated with some cases of anosmia [A32414], [A32409], [A32410], [L2080]. ... Although it has been nasally administered for treating the common cold, this route of administration …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Oxetacaine, also called oxethazaince, is a potent surface analgesic with the molecular formula N, N-bis-(N-methyl-N-phenyl-t-butyl-acetamide)-beta-hydroxyethylamine that conserves its unionized form at low pH levels. Its actions have shown to relieve dysphagia, relieve pain due to reflux, chronic gastritis, and duodenal ulcer. Oxetacaine is approved by Health Canada since 1995 for...
Approved
Investigational
Matched Description: … [L1113] It is also in the list of approved derivatives of herbal products by the EMA.[L2816] …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages.
Approved
Matched Mixtures name: … Tincture Of Iodine 2.5% ... De La Cruz Tincture of Iodine …
Matched Products: … University of Michigan ... Essence Of Beauty Snowy Apple ... Essence Of Beauty Wind Kissed …
Perflutren, a diagnostic drug that is intended to be used for contrast enhancement during the indicated echocardiographic procedures, is comprised of lipid-coated microspheres filled with octafluoropropane(OFP) gas. When exposed to ultrasound waves, the microspheres resonate and "echo" strong signals back to the ultrasound machine. The difference in density between the...
Approved
Matched Description: … During echocardiography, activated Perflutren enhances images of the inner edges or borders of the heart ... to be used for contrast enhancement during the indicated echocardiographic procedures, is comprised of ... difference in density between the gas-filled bubbles and the blood around them creates an increased level of
Matched Categories: … Diagnostic Uses of Chemicals …
Tigecycline is a glycylcycline antibiotic developed and marketed by Wyeth under the brand name Tygacil. It was developed in response to the growing prevalence of antibiotic resistance in bacteria such as Staphylococcus aureus. It was granted fast-track approval by the U.S. Food and Drug Administration (FDA) on June 17, 2005.
Approved
Matched Description: … It was developed in response to the growing prevalence of antibiotic resistance in bacteria such as Staphylococcus …
Matched Categories: … combinations of tetracyclines …
One of the penicillins which is resistant to penicillinase but susceptible to a penicillin-binding protein. It is inactivated by gastric acid so administered by injection.
Approved
Investigational
Matched Description: … One of the penicillins which is resistant to penicillinase but susceptible to a penicillin-binding protein …
Matched Categories: … combinations of penicillins …
Sarecycline is a semi-synthetic derivative of tetracycline that was initially discovered by Paratek Pharmaceuticals from Boston, MA but then licensed to Warner Chilcott of Rockaway, NJ in July of 2007 . After completing various phase-II and phase-III trials demonstrating its effectiveness in treating moderate to severe facial acne vulgaris [A39993,...
Approved
Investigational
Matched Description: … from Boston, MA but then licensed to Warner Chilcott of Rockaway, NJ in July of 2007 [A40005]. ... inflammatory lesions of non-nodular moderate to severe acne vulgaris in patients nine years of age and ... of young adults aged 12 to 25 years globally - with the possibility of permanent physical and mental …
Matched Categories: … combinations of tetracyclines …
Temocillin has been investigated in Infection, Liver Dysfunction, and Urinary Tract Infection.
Approved
Investigational
Matched Categories: … combinations of penicillins …
Phthalylsulfathiazole is a broad spectrum antibiotic which is part of the drug class, sulfonamides. It was used as an antibiotic for bowel surgery, and for infections of the colon .
Approved
Matched Description: … It was used as an antibiotic for bowel surgery, and for infections of the colon [A175006]. ... Phthalylsulfathiazole is a broad spectrum antibiotic which is part of the drug class, sulfonamides. …
Matched Categories: … combinations of sulfonamides …
Gallium (Ga) 68 prostate-specific membrane antigen (PSMA)-11, or Ga-68 gozetotide, is a radiopharmaceutical agent used to identify and assess prostate-specific membrane antigen (PSMA)-positive lesions in adult men with prostate cancer during positron emission tomography (PET). Prostate cancer is one of the most commonly diagnosed cancers among men in Western countries...
Approved
Matched Description: … [L43542] In December of the same year, the drug was fully authorized by the EMA. ... [L26981] Prostate cancer is one of the most commonly diagnosed cancers among men in Western countries ... Human Use (CHMP) recommended Ga-68 gozetotide be granted marketing authorization for the diagnosis of
Matched Categories: … Diagnostic Uses of Chemicals …
Protriptyline hydrochloride is a dibenzocycloheptene-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, protriptyline does not affect mood or arousal, but may cause sedation. In depressed individuals, protriptyline exerts a positive...
Approved
Matched Description: … Protriptyline may be used for the treatment of depression. ... TCAs are potent inhibitors of serotonin and norepinephrine reuptake. ... See toxicity section below for a complete listing of side effects. …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Latanoprost is a prodrug analog of prostaglandin F2 alpha that is used to treat elevated intraocular pressure (IOP). It was initially approved by the FDA in 1998. Latanoprost is the first topical prostaglandin F2 alpha analog used for glaucoma treatment. It has been found to be well-tolerated and its use...
Approved
Investigational
Matched Description: … Latanoprost is a prodrug analog of prostaglandin F2 alpha that is used to treat elevated intraocular …
Persistent forms of tuberculosis (TB) have proven to be a major cause of global morbidity and mortality and a cause for significant concern. Research in recent years has been geared toward the development of novel therapies that target persistent forms of this disease, which have shown resistance to standard therapy...
Approved
Matched Description: … Persistent forms of tuberculosis (TB) have proven to be a major cause of global morbidity and mortality ... forms of this disease, which have shown resistance to standard therapy regimens. ... Research in recent years has been geared toward the development of novel therapies that target persistent …
Matched Categories: … Drugs for Treatment of Tuberculosis …
Corifollitropin alfa, also known as Elonva is used in women undergoing fertility treatment to stimulate the development of more than one mature egg (oocyte) at a time in the ovaries. This drug used together with a gonadotropin-releasing hormone (GnRH) antagonist, a type of medicine also used in fertility treatments. Elonva...
Approved
Investigational
Matched Description: … risk of ovarian hyperstimulation in the high responder study group of women [L2276], [A32526]. ... effectiveness of this drug, however, warns at the same time against the possibility of an increased ... In July 2014, Merck announced the receipt of a Complete Response Letter (CRL) from the U.S. …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Displaying drugs 76 - 100 of 8517 in total