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Displaying drugs 76 - 100 of 370 in total
Tagraxofusp is a CD123-directed cytotoxin. It is a fusion protein composed of a human interleukin-3 (IL-3) that is genetically fused to the catalytic and translocation domains of truncated diphtheria toxin (DT) produced in Escherichia coli.[A253762, A253887, L43702] Tagraxofusp received its first global approval by the FDA on December 21, 2018...
Approved
Investigational
Rizatriptan is a second-generation triptan and a selective 5-HT1B and 5-HT1D receptor agonist. Used in the treatment of migraines, rizatriptan was first approved in the US in 1998. Rizatriptan is available in oral tablets, orally disintegrating tablets (wafers), and oral film formulations.
Approved
Sodium fluoride is an inorganic chemical compound that is a source of the fluoride ion in many applications, including dental care and radiographic imaging when it is used as Fluoride ion F-18. Sodium fluoride's benefits on dental health were first observed in the 1930s, when individuals in communities with fluoridated...
Approved
Matched Mixtures name: … VINATAL DHA CAPSULA DE GELATINA BLANDA …
Also known as Aspirin, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. Acetylsalicylic acid has both anti-inflammatory and antipyretic effects. This drug also inhibits platelet aggregation and is used in the prevention of blood clots stroke, and myocardial infarction...
Approved
Vet approved
Matched Categories: … Heparin
Homosalate is an organic compound that belongs to salicylates. It is an ester formed from salicylic acid and 3,3,5-trimethylcyclohexanol, a derivative of cyclohexanol. Salicylates prevent direct skin exposure to the sun’s harmful rays by absorbing ultraviolet (UV) light. Homosalate specifically absorbs short-wave UVB rays, which are associated with DNA damage...
Approved
Investigational
Matched Mixtures name: … Introstem Stem Cell Active Defense …
Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone. It forms colorless crystals that are readily soluble in most organic solvents. It is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays.
Approved
Investigational
Matched Mixtures name: … Introstem Stem Cell Active Defense …
Also known as Ethylhexyl Salicylate. Octyl salicylate is an oil soluble chemical sunscreen agent that absorbs UVB radiation. It does not protect against UVA. Octyl salicylate is used to augment the UVB protection in a sunscreen. Salicylates are weak UVB absorbers and they are generally used in combination with other...
Approved
Investigational
Matched Mixtures name: … Introstem Stem Cell Active Defense …
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor...
Approved
Investigational
Matched International brands: … Heparin LEO …
Matched Synonyms: … Unfractionated heparin
Matched Name: … Heparin
Matched Description: … Unfractionated heparin is more specific than LMWH for thrombin. ... Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers ... UH is different from low molecular weight heparin (LMWH) in the following ways: the average molecular …
Matched Mixtures name: … Heparin Sodium in Dextrose ... Heparin Sodium in Dextrose ... Heparin Sodium in Dextrose …
Matched Salts name: … Heparin sodium ... Heparin calcium …
Matched Categories: … heparin ... heparin ... heparin ... Heparin Group ... Heparin and similars …
Matched Products: … Heparin ... Heparin Sodium ... Heparin sodium …
Fondaparinux (Arixtra) is a synthetic anticoagulant agent consisting of five monomeric sugar units and a O-methyl group at the reducing end of the molecule. It is structurally similar to polymeric glycosaminoglycan heparin and heparan sulfate (HS) when they are cleaved into monomeric units. The monomeric sequence in heparin and HS...
Approved
Investigational
Matched Synonyms: … Natural heparin pentasaccharide …
Matched Description: … Once bound to heparin or HS, the anticoagulant activity of ATIII is potentiated by 1000-fold. ... It is structurally similar to polymeric glycosaminoglycan heparin and heparan sulfate (HS) when they ... The monomeric sequence in heparin and HS is thought to form the high affinity binding site for the natural …
Remestemcel-L is a third-party, off-the-shelf suspension of ex-vivo cultured adult human mesenchymal stem cells intended for intravenous infusion. The mesenchymal stem cells are derived from the bone marrow of unrelated and human leukocyte antigen (HLA)–unmatched healthy adult donors and have the ability to differentiate into different tissue cells. It was...
Approved
Investigational
Matched Synonyms: … Adult human mesenchymal stem cells ... Allogeneic human mesenchymal stem cell …
Matched Description: … Remestemcel-L is a third-party, off-the-shelf suspension of ex-vivo cultured adult human mesenchymal stem ... The mesenchymal stem cells are derived from the bone marrow of unrelated and human leukocyte antigen ... aGvHD is a T-cell mediated disease that occurs after allogeneic hematopoietic stem cell transplant and …
Matched Categories: … Stem Cells ... Multipotent Stem Cells …
Rhubarb allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Rhubarb stem ... Rheum rhabarbarum stem
Rumex crispus top allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Rumex crispus flower/leaf/stem extract …
A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes. It is a member of the serpin superfamily.
Approved
Matched Synonyms: … Heparin cofactor B …
Purslane is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Portulaca Oleracea Flower/leaf/stem Extract …
Approved
Experimental
Matched Synonyms: … Rhamnus purshiana stem bark …
Artesunate is indicated for the initial treatment of severe malaria. The World Health Organization recommends artesunate as first line treatment for severe malaria. Artesunate was developed out of a need for a more hydrophilic derivative of artemisinin. Artesunate was granted FDA approval on 26 May 2020.
Approved
Investigational
Motixafortide is a cyclic peptide hematopoietic stem cell mobilizer used to improve stem cell collection prior to autologous transplantation. Hematopoietic stem cell transplantation (HSCT) is commonly employed in the context of hematologic cancers - high-dose chemotherapy regimens destroy cancerous blood cells, which are then replaced via infusion of the patient's...
Approved
Investigational
Matched Description: … Motixafortide is a cyclic peptide hematopoietic stem cell mobilizer used to improve stem cell collection ... cell mobilization prior to autologous stem cell transplant in patients with multiple myeloma. ... [L48116] Hematopoietic stem cell transplantation (HSCT) is commonly employed in the context of hematologic …
Matched Categories: … Hematopoietic Stem Cell Mobilizer …
Certoparin is part of the heparins of low molecular weight that presents high activity against the coagulation factor Xa. It is normally used to prevent deep venous thrombosis.
Approved
Investigational
Matched Categories: … Heparin and similars ... Heparin (Low Molecular Weight) …
Reviparin is a low molecular weight heparin which seems to have a better safety profile than unfractionated heparin. It is prepared from porcine intestinal mucosa by nitrous acid depolymerization. Reviparin has a molecular weight of 3.9 kDa. It was developed by Abbott laboratories and in 2009, reviparin presented an orphan...
Approved
Investigational
Matched Description: … heparin. ... Reviparin is a low molecular weight heparin which seems to have a better safety profile than unfractionated …
Matched Categories: … Heparin and similars ... Heparin (Low Molecular Weight) …
Tinzaparin is a low molecular weight heparin (LMWH), produced by enzymatic depolymerization of unfractionated heparin from porcine intestinal mucosa. It is a heterogeneous mixture of with an average molecular weight between 5500 and 7500 daltons. Tinzaparin is composed of molecules with and without a special site for high affinity binding...
Approved
Matched Description: … heparin from porcine intestinal mucosa. ... Tinzaparin is a low molecular weight heparin (LMWH), produced by enzymatic depolymerization of unfractionated ... are less effective at inactivating factor IIa due to their shorter length compared to unfractionated heparin
Matched Categories: … Heparin and similars ... Heparin (Low Molecular Weight) …
Dimethicone is a silicone oil that is also known as polydimethylsiloxane (PDMS). It has viscoelastic properties. Dimethicone is used as a surfactant, antifoaming agent, carminative in various products such as medical devices, food products, and lubricants. It is used in a number of health and beauty products including hair care...
Approved
Matched Products: … Oxy Stem M ... Oxy Stem M Serum ... Easter Stem Cell Hair Perfection 22 …
Dicoumarol is an oral anticoagulant agent that works by interfering with the metabolism of vitamin K. In addition to its clinical use, it is also used in biochemical experiments as an inhibitor of reductases.
Approved
Argatroban is a direct, selective thrombin inhibitor. The American College of Cardiologists (ACC) recommend using bivalirudin or argatroban in patients who have had, or at risk for, heparin induced thrombocytopenia (HIT) and are undergoing percutaneous coronary intervention. Argatroban is a non-heparin anticoagulant shown to both normalize platelet count in patients...
Approved
Investigational
Matched Description: … Argatroban is a non-heparin anticoagulant shown to both normalize platelet count in patients with HIT ... Cardiologists (ACC) recommend using bivalirudin or argatroban in patients who have had, or at risk for, heparin
Treosulfan is under investigation in Allogeneic Haematopoietic Stem Cell Transplantation. Treosulfan has been investigated for the treatment of Lymphoblastic Leukemia, Acute, Childhood.
Approved
Investigational
Matched Description: … Treosulfan is under investigation in Allogeneic Haematopoietic Stem Cell Transplantation. …
Danaparoid is a low-molecular-weight heparinoid with an average molecular weight of 5500 Daltons consisting of a mixture of glycosaminoglycans . The active constituents are heparan, dermatan and DB09301 , and they are isolated from the porcine intestinal mucosa [FDA Label]. Danaparoid possesses a potent antithrombic activity that works by inhibiting...
Approved
Withdrawn
Matched Description: … cross-reactivity in heparin-intolerant patients. ... Danaproid is used in the treatment of heparin-induced thrombocytopenia (HIT) as an off-label indication ... It is chemically distinct from heparin by containing different protein binding properties, thus has lower …
Matched Categories: … Heparin and similars …
Displaying drugs 76 - 100 of 370 in total