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Displaying drugs 201 - 225 of 4111 in total
TRK-001 is an autologous regulatory T-cell therapy. It is being investigated for the prevention of graft rejection following solid organ transplantation.
Investigational
Matched Synonyms: … Regulatory T Cells (T-Regs), Expanded with Interleukin-2, ExpAct Beads (CD3/CD28; Miltenyi), Rapamycin and
Investigational
Matched Synonyms: … interfering RNA (siRNA) therapeutic directed against transforming growth factor-beta 1 (TGF-beta 1) and
PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) designed to down-regulate the expression of EVI1 oncogene in cancer cells.
Investigational
Matched Synonyms: … Nanocomplex consisting of a small interfering RNA that targets the human EV11 oncogenic transcription factor and
Matched Description: … PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) …
Leuprolide is a synthetic 9-residue peptide analogue of gonadotropin-releasing hormone (GnRH). Unlike the endogenous decapeptide GnRH, leuprolide contains a single D-amino acid (D-leucyl) residue, which helps to increase its circulating half-life from three to four minutes to approximately three hours. As a GnRH mimic, leuprolide is capable of binding to...
Approved
Investigational
Matched Iupac: … propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido]-4-methylpentanamido]pentanoyl]-N-ethylpyrrolidine …
Matched Description: … Unlike the endogenous decapeptide GnRH, leuprolide contains a single D-amino acid (D-leucyl) residue, ... downstream modulation of both gonadotropin hormone and sex steroid levels. ... [A203222] As a GnRH mimic, leuprolide is capable of binding to the GnRH receptor (GnRHR) and inducing …
Matched Mixtures name: … Leuprolide Acetate ... Leuprolide Acetate ... Leuprolide Acetate
Matched Salts name: … Leuprolide acetate
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Hormones and Related Agents ... leuprorelin and bicalutamide …
Matched Products: … POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 45mg ... POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 22.5mg ... POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 7.5mg …
Methyl cellulose polymer consisting of numerous linked glucose molecules used as a stabiliser, thickener and emulsifier for foodstuffs and cosmetics. The Degree of Substitution (DS) of a given form of methyl cellulose is defined as the average number of substituted hydroxyl groups per glucose with a theoretical maximum of 3,...
Approved
Matched Description: … Like cellulose, it is not digestible, not toxic, and not allergenic ... Methyl cellulose is a hydrophilic white powder in pure form and dissolves in cold (but not in hot) water ... emulsifier for foodstuffs and cosmetics. …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Foster and Thrive Fiber Laxative 188 ... Premier Value Fiber Therapy …
Zenocutuzumab is under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy in HER2+ and With Endocrine Therapy in ER+ and Low HER2 Breast Cancer).
Investigational
Matched Synonyms: … Immunoglobulin g1, bispecific, anti-(human epidermal growth factor receptors, her2 and her3) (humanized ... antibody with enhanced antibody-dependent cell-mediated cytotoxicity (adcc) activity targeting her2 and
Matched Description: … With Endocrine Therapy in ER+ and Low HER2 Breast Cancer). ... under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy in HER2+ and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Triptorelin is a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion. After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production and testicular and ovarian steroidogenesis. Serum testosterone concentrations may fall to levels...
Approved
Vet approved
Matched Synonyms: … pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2 ... (6-D-Tryptophan)luteinizing hormone-releasing hormone ... Luteinizing hormone-releasing factor (pig), 6-D-tryptophan
Matched Iupac: … (2S)-N-[(2S)-5-carbamimidamido-1-[(2S)-2-[(carbamoylmethyl)carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl …
Matched Description: … and testicular and ovarian steroidogenesis. ... After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production …
Matched Salts name: … Triptorelin acetate
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Hormones and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION 11.25 mg/vial ... POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION 3.75 mg/vial …
Sodium fluoride is an inorganic chemical compound that is a source of the fluoride ion in many applications, including dental care and radiographic imaging when it is used as Fluoride ion F-18. Sodium fluoride's benefits on dental health were first observed in the 1930s, when individuals in communities with fluoridated...
Approved
Matched Description: … Now, sodium fluoride may be found in a variety of gels, varnishes, rinses, toothpaste products, and fluoride ... chemical compound that is a source of the fluoride ion in many applications, including dental care and ... control dental caries is safe when used correctly and is highly effective in reducing the prevalence …
Matched Mixtures name: … Addamel N ... ADDAMEL N ... ADDAMEL N
Matched Categories: … Alimentary Tract and Metabolism ... Mouthwashes and Gargles …
Matched Products: … T-series ... Amino Acid Fragrancemouthwash Dawn ... Amino Acid Fragrancemouthwash Blossom …
Investigational
Matched Synonyms: … engager antibody with a single chain fc moiety that binds to b cell maturation antigen surface receptor and
Investigational
Matched Synonyms: … Flt3 ligand, IL-7, IL-15 and IL-2 to generate the NK cell ... The cells are expanded and differentiated in the presence of cytokines including thrombopoietin, SCF, ... Allogeneic natural killer (NK) cells derived from CD34+ human placental stem/progenitor cells. …
Investigational
Matched Synonyms: … 3-butylidenephthalide, mixture of cis and trans isomers ... N-butylidenephthalide, (e)+(z) …
Matched Categories: … Phthalic Acids ... Acids, Carbocyclic ... Carboxylic Acids
Ranitidine is a commonly used drug, classified as a histamine H2-receptor antagonist, and belongs to the same drug class as cimetidine and famotidine. This drug helps to prevent and treat gastric-acid associated conditions, including ulcers, because of its ability to decrease gastric acid secretion.[A176759,L10818] Ranitidine is often referred to as...
Approved
Withdrawn
Matched Description: … Ranitidine is a commonly used drug, classified as a histamine H2-receptor antagonist, and belongs to ... This drug helps to prevent and treat gastric-acid associated conditions, including ulcers, because of ... associated conditions and is therefore widely used in GERD and other gastric-acid related conditions …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) ... Acid Reducers ... Histamine Antagonists ... Gastric Acid Lowering Agents …
Matched Products: … Up and Up Acid Reducer Non Prescription Strength ... Berkley and Jensen Acid Reducer ... Berkley and Jensen Acid Reducer Maximum Strength …
Suratadenoturev is a gene-modified oncolytic adenovirus expressing the telomerase reverse transcriptase gene.
Investigational
Matched Synonyms: … -5) in which the E1 gene, including its normal transcriptional regulatory element, has been deleted and ... telomerase reverse transcriptase (hTERT) and IRES, respectively. ... A replication-competent adenovirus type 5 in which the E1A and E1B genes are under the control of a human …
Carboxymethylcellulose is a cellulose derivative that consists of the cellulose backbone made up of glucopyranose monomers and their hydroxyl groups bound to carboxymethyl groups. It is added in food products as a viscosity modifier or thickener and emulsifier. It is also one of the most common viscous polymers used in...
Approved
Investigational
Matched Description: … is a cellulose derivative that consists of the cellulose backbone made up of glucopyranose monomers and ... It is added in food products as a viscosity modifier or thickener and emulsifier. ... It is also one of the most common viscous polymers used in artificial tears, and has shown to be effective …
Matched Mixtures name: … Equate Day and Night Restore Tears ... Refresh Trial Pack (refresh Tears, Refresh Liquigel and Refresh Ultra) ... Refresh Trial Pack (refresh Tears, Refresh Liquigel and Refresh Ultra) …
Matched Categories: … Anorexigenic Agents & Respiratory and CNS Stimulants …
Matched Products: … Up and Up Lubricant Refreshing ... Up and Up Lubricant Refreshing Tears ... Up and Up Lubricant …
Loratadine is a second generation antihistamine used to manage symptoms of allergic rhinitis. A lack of sedative and CNS adverse effects make loratadine, along with other second generation antihistamines, preferable over their 1st generation counterparts in many clinical situations.
Approved
Investigational
Matched Description: … [A176435] A lack of sedative and CNS adverse effects make loratadine, along with other second generation …
Matched Mixtures name: … Allergy and Congestion Relief Non Drowsy ... Allergy and Congestion Relief Non Drowsy ... Wal Itin D Non Drowsy 24 Hour Allergy and Congestion …
Matched Categories: … Histamine H1 Antagonists, Non-Sedating ... Loratadine and derivatives ... Histamine Antagonists ... Histamine H1 Antagonists …
Matched Products: … Berkley and Jensen Loratadine Non Drowsy ... Premier Value Childrens Loratadine ... Up and Up Allergy Relief …
Lanolin is a yellow fat obtained from sheep's wool. It is used as an emollient, cosmetic, and pharmaceutic aid . The US federal code of regulations states that lanolin in the concentration range of 12-50% may be included in over the counter skin ointments . Lanolin is the purified, secreted...
Approved
Matched Description: … It is used as an emollient, cosmetic, and pharmaceutic aid [L2580]. ... Lanolin is used in the protection, treatment, and cosmetic enhancement of human skin. ... as an active ingredient in over the counter topical products such as ointments, lubricants, lotions and
Matched Mixtures name: … Vitamins A and D Diaper Rash ... PETROLATUM and LANOLIN ... Blistex Revive and Restore …
Matched Categories: … Basic Ointments and Protectants …
Matched Products: … Soothe and Cool Free Medseptic Skin Protectant …
Calcium carbonate is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. Subsequent increases in pH may inhibit the action of pepsin. An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects. Calcium carbonate may also...
Approved
Investigational
Matched Synonyms: … Carbonic acid calcium salt (1:1) …
Matched Description: … An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects. ... It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. …
Matched Mixtures name: … Berkley and Jensen Acid Controller Complete ... Up and Up dual action acid controller complete ... Up and Up Acid Controller Complete Dual Action …
Matched Categories: … ascorbic acid (vit C) and calcium ... Alimentary Tract and Metabolism ... Antacids and Adsorbents ... Carbonic Acid ... Gastric Acid Lowering Agents …
Matched Products: … ACID STOP ... Medique Ban-acid Maximum Strength 750 ... D N B Re …
AB-201 is a CAR-NK cell therapy targeted against HER2. It is under investigation for the treatment of HER2-positive cancers, including breast and gastric carcinomas.
Investigational
Matched Synonyms: … a HER2-directed CAR and secrete IL-15 ... Ex vivo expanded allogeneic cord blood-derived NK cells that have been genetically modified to express …
Matched Description: … [L48340] It is under investigation for the treatment of HER2-positive cancers, including breast and gastric ... AB-201 is a CAR-NK cell therapy targeted against HER2. …
OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human gp91phox gene. It is being investigated for the treatment of X-linked chronic granulomatous disease.
Investigational
Matched Synonyms: … Autologous CD34+ enriched cell population that contains hematopoietic stem and progenitor cells transduced …
Matched Description: … OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells …
Haemophilus influenzae type b strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen is an active immunization as a booster dose given intramuscularly to pediatric patients who have received a primary series with a Haemophilus b Conjugate Vaccine that is licensed for primarly immunization. The vaccine contains Haemophilus b capsular polysaccharide...
Approved
Investigational
Matched Synonyms: … Haemophilus influenzae type B-PRP and tetanus toxoid conjugate (PRP-T) …
Matched Description: … These are heat inactivated and purified. ... immunization as a booster dose given intramuscularly to pediatric patients who have received a primary series
Thrombotic thrombocytopenic purpura (TTP) is a rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and various degrees of organ damage. It may be inherited (congenital TTP; cTTP) or acquired due to autoantibodies (immune-mediated TTP; iTTP), although cTTP accounts for <5% of all cases of TTP. Patients with cTTP...
Approved
Investigational
Matched Synonyms: … Recombinant disintegrin and metalloprotease with thrombospondin type 1 motifs …
Matched Description: … rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and ... Patients with cTTP have a severe deficiency of a plasma metalloproteinase called ADAMTS13 (a disintegrin and ... thrombospondin type 1 motif, member 13), which is responsible for cleaving large von Willebrand factor multimers and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Glycerol monostearate, commonly known as GMS, is the glycerol ester of stearic acid . It is commonly used as an emulsifier in foods.
Experimental
Matched Synonyms: … Geleol mono and diglycerides ... Stearic acid, monoester with glycerol …
Matched Description: … Glycerol monostearate, commonly known as GMS, is the glycerol ester of stearic acid . …
Povidone-iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It contains from 9.0% to 12.0% available iodine, calculated on a dry basis. This unique complex was discovered in 1955 at the Industrial Toxicology Laboratories in Philadelphia by H. A. Shelanski and M. V. Shelanski. During in...
Approved
Matched Description: … Povidone-iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine ... Shelanski and M. V. Shelanski. ... Povidone-iodine was immediately marketed, and has since become the universally preferred iodine antiseptic …
Matched Mixtures name: … Mountain Series Weekender Medical ... Mountain Series Weekender Medical ... Physician EZ Use Joint Tunnel and Trigger Kit …
Matched Categories: … Antiseptics and Disinfectants ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Premier Value Povidone Iodine ... OP First Aid Series Povidone Iodine Prep Pad ... Fresh and Pure …
Tolnaftate is a synthetic over-the-counter anti-fungal agent. It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot and ringworm. It is sold under several brand names, most notably Tinactin and Odor Eaters.
Approved
Investigational
Vet approved
Matched International brands: … NP-27 …
Matched Synonyms: … m,N-Dimethylthiocarbanilic acid O-2-naphthyl ester ... Methyl (3-methylphenyl)carbamothioic acid O-2-naphthalenyl ester ... 2-Naphthyl N-methyl-N-(3-tolyl)thionocarbamate …
Matched Iupac: … N-methyl-N-(3-methylphenyl)-1-(naphthalen-2-yloxy)methanethioamide …
Matched Description: … and ringworm. ... It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot ... It is sold under several brand names, most notably Tinactin and Odor Eaters. …
Matched Mixtures name: … Terbinafine HCl Chlortimazole and Tolnaftate …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids
Matched Products: … Woodwards Mycocide Clinical NS ... Premier Value Tolnaftate Antifungal ... Up and Up Soothing Antifungal …
Miconazole is a broad-spectrum azole antifungal with some activity against Gram-positive bacteria as well. It is widely used to treat mucosal yeast infections, including both oral and vaginal infections; although intravenous miconazole is no longer available, a wide variety of suppositories, creams, gels, and tablet-based products are available.[L14021, L14024, L14027,...
Approved
Investigational
Vet approved
Matched Description: … , and tablet-based products are available. ... [A203636] It is widely used to treat mucosal yeast infections, including both oral and vaginal infections ... [A203636, A203639] Miconazole was first synthesized in 1969 and first granted FDA approval on January …
Matched Mixtures name: … Up and Up Miconazole 1 ... Up and Up Miconazole 1 ... Up and Up Miconazole 1 …
Matched Categories: … Antiinfectives and Antiseptics for Local Oral Treatment ... Genito Urinary System and Sex Hormones ... Imidazole and Triazole Derivatives ... Vaginal Creams, Foams, and Jellies ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … MICONAZOL ACIS CREME ... Premier Value Miconazole 3 ... Up and Up Miconazole 7 …
Displaying drugs 201 - 225 of 4111 in total