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Thrombomodulin Alfa is a novel, recombinant and soluble thrombomodulin (ART-123). It is a human protein with both thrombin inhibiting and protein C stimulating activities, for the potential treatment of thromboembolism and blood clotting disorders, such as disseminated intravascular thromboembolism.
Approved
Investigational
Matched Synonyms: … Thrombomodulin Alfa ... Thrombomodulin (human 498-amino acid fragment) …
Matched Name: … Thrombomodulin Alfa
Matched Description: … Thrombomodulin Alfa is a novel, recombinant and soluble thrombomodulin (ART-123). ... It is a human protein with both thrombin inhibiting and protein C stimulating activities, for the potential ... treatment of thromboembolism and blood clotting disorders, such as disseminated intravascular thromboembolism …
Matched Categories: … Amino Acids, Peptides, and Proteins …
The lysosomal acid lipase (LAL) enzyme is found in lysosomes and is primarily responsible for the metabolism of lipids, and its absence or deficiency results in the accumulation of lipids in various organs. This lipid accumulation can lead to end-organ damage in the form of liver dysfunction or malabsorption secondary...
Approved
Investigational
Matched Synonyms: … Sebelipasa alfa ... Sebelipase alfa
Matched Name: … Sebelipase alfa
Matched Description: … The lysosomal acid lipase (LAL) enzyme is found in lysosomes and is primarily responsible for the metabolism ... [L39337] Sebelipase alfa is a recombinant form LAL approved for the treatment of LAL deficiency. ... It was first approved by both the FDA and EMA in 2015 and is marketed under the brand name Kanuma (Alexion …
Matched Categories: … sebelipase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Turoctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally occurring B-domain. Turoctocog alfa is produced in Chinese hamster ovary (CHO) cells without addition of any...
Approved
Investigational
Matched Synonyms: … Turoctocog alfa
Matched Name: … Turoctocog alfa
Matched Description: … During secretion, some rFVIII molecules are cleaved at the C-terminal of the heavy chain (HC) at amino acid ... Turoctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence ... Turoctocog alfa is produced in Chinese hamster ovary (CHO) cells without addition of any human- or animal-derived …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … NovoEight 500IU Powder and Solvent for Solution for Injection ... NovoEight 1000IU Powder and Solvent for Solution for Injection ... NovoEight® 250IU Powder and Solvent for Solution for Injection …
Approved
Investigational
Matched Synonyms: … Lonoctocog alfa
Matched Name: … Lonoctocog alfa
Matched Products: … AFSTYLA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 250IU/VIAL ... AFSTYLA 250IU powder and solvent for solution for injection ... AFSTYLA 500IU powder and solvent for solution for injection …
Olipudase alfa is recombinant human acid sphingomyelinase. It is the first and only enzyme replacement therapy in the world for the treatment of Acid Sphingomyelinase Deficiency (ASMD), also known as Niemann–Pick disease. ASMD is a rare lysosomal storage disease caused by mutations in the SMPD1 gene, leading to a deficiency...
Approved
Investigational
Matched Synonyms: … Olipudase alfa
Matched Name: … Olipudase alfa
Matched Description: … Olipudase alfa is recombinant human acid sphingomyelinase. ... [A251590] It is the first and only enzyme replacement therapy in the world for the treatment of Acid ... , liver, spleen, kidneys, and bone marrow. …
Matched Categories: … olipudase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Asfotase alfa is a first-in-class bone-targeted enzyme replacement therapy designed to address the underlying cause of hypophosphatasia (HPP)—deficient alkaline phosphatase (ALP). Hypophosphatasia is almost always fatal when severe skeletal disease is obvious at birth. By replacing deficient ALP, treatment with Asfotase Alfa aims to improve the elevated enzyme substrate levels...
Approved
Investigational
Matched Synonyms: … Asfotase alfa
Matched Name: … Asfotase alfa
Matched Description: … Asfotase alfa was first approved by Pharmaceuticals and Medicals Devices Agency of Japan (PMDA) on July ... levels and improve the body's ability to mineralize bone, thereby preventing serious skeletal and systemic ... patient morbidity and premature death. …
Matched Categories: … asfotase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. It is produced in genetically modified Chinese hamster ovary (CHO) cells using recombinant DNA technology. The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and...
Approved
Matched Synonyms: … Dornasa alfa ... Dornase alfa ... Dornase alfa, recombinant …
Matched Name: … Dornase alfa
Matched Description: … The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. ... Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and 5´-phosphooligonucleotide end products ... Enzymatic breakdown of this extracellular DNA appears to reduce sputum viscosity and viscoelasticity. …
Matched Categories: … dornase alfa (desoxyribonuclease) ... Enzymes and Coenzymes ... Cough and Cold Preparations ... Amino Acids, Peptides, and Proteins …
Velmanase alfa is a recombinant human lysosomal alpha-mannosidase developed for enzyme replacement therapy to treat alpha-mannosidosis. Alpha-mannosidosis is a rare autosomal recessive lysosomal storage disorder. Patients with alpha-mannosidosis have a genetic mutation that causes a deficiency in the lysosomal enzyme alpha-mannosidase, which is an enzyme responsible for breaking down complex...
Approved
Investigational
Matched Synonyms: … Velmanase alfa ... Velmanase alfa-tycv …
Matched Name: … Velmanase alfa
Matched Description: … Velmanase alfa has an amino acid sequence of the monomeric protein identical to the naturally occurring ... deterioration, such as skeletal abnormalities, motor function impairment, intellectual disability, and ... sugars in the body leads to an array of clinical manifestations leading to progressive neuromuscular and
Matched Categories: … velmanase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Vonicog alfa is a recombinant von Willebrand factor manufactured by Baxalta. It was FDA approved in December 2015. The gen of von Willebrand factor was first cloned in 1985 by Stuart Orkin and David Ginsburg. By the EMA, vonicog alfa is still under clinical analysis.
Approved
Investigational
Matched Synonyms: … Vonicog alfa
Matched Name: … Vonicog alfa
Matched Description: … [A32230] The gen of von Willebrand factor was first cloned in 1985 by Stuart Orkin and David Ginsburg ... Vonicog alfa is a recombinant von Willebrand factor manufactured by Baxalta. ... [L1849] By the EMA, vonicog alfa is still under clinical analysis.[L1862] …
Interferon a (human leukocyte protein moiety reduced). A type I interferon consisting of 165 amino acid residues with lysine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent. An oral form is...
Approved
Investigational
Matched Synonyms: … Interferon alfa-2a ... Interferon-alfa-2a ... Interferon alfa-2a,recombinant …
Matched Name: … Interferon alfa-2a …
Matched Description: … A type I interferon consisting of 165 amino acid residues with lysine in position 23. ... This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes …
Matched Categories: … Alfa Interferons ... interferon alfa-2a ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Albutrepenonacog alfa (rIX-RFP) is a recombinant fusion protein that links a recombinant coagulation factor IX (rFIX) with a recombinant human albumin (rAlbumin). It was developed by CSL Behring Canada, Inc and approved by Health Canada on April 26, 2017. It was also approved by FDA and EMA in 2016. It...
Approved
Matched Synonyms: … Albutrepenonacog alfa
Matched Name: … Albutrepenonacog alfa
Matched Description: … Albutrepenonacog alfa (rIX-RFP) is a recombinant fusion protein that links a recombinant coagulation ... It was also approved by FDA and EMA in 2016. ... It is currently marketed in the forms of 250, 500, 1000 and 2000 IU/vial.[L2305] …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Products: … IDELVION 250 IU powder and solvent for solution for injection ... IDELVION 500 IU powder and solvent for solution for injection ... IDELVION 1000 IU powder and solvent for solution for injection …
Peginterferon alfa-2b is a form of recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Matched Synonyms: … Peginterferon alfa-2b …
Matched Name: … Peginterferon alfa-2b …
Matched Description: … Peginterferon alfa-2b is derived from the alfa-2b moeity of recombinant human interferon and acts by ... When combined together, Peginterferon alfa-2b and [Ribavirin] have been shown to achieve a SVR between ... aggravation and development of endocrine and autoimmune disorders, retinopathies, cardiovascular and
Matched Categories: … Alfa Interferons ... peginterferon alfa-2b ... Amino Acids, Peptides, and Proteins ... peginterferon alfa-2b, combinations ... Antineoplastic and Immunomodulating Agents …
Rurioctocog alfa pegol is a pegylated recombinant human coagulation factor VIII or antihemophilic factor. Factor VIII is an essential protein involved in normal blood clotting; thus, a deficient level of functional factor VIII is associated with an elevated risk for excessive bleeding caused by spontaneous or secondary events like trauma...
Approved
Experimental
Matched Synonyms: … Rurioctocog alfa pegol …
Matched Name: … Rurioctocog alfa pegol …
Matched Description: … Bleeding in joints is a common manifestation of hemophilia A, and bleeding episodes can be severe and ... A to manage and prevent bleeding episodes. ... [L40119] Rurioctocog alfa pegol is a covalent conjugate of [octocog alfa], which is a recombinant …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … ADYNOVATE 1500IU Powder and Solvent for Solution for Injection ... ADYNOVATE 2000IU Powder and Solvent for Solution for Injection ... ADYNOVATE 1000IU Powder and Solvent for Solution for Injection …
Interferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). A type I interferon consisting of 165 amino acid residues with arginine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent.
Approved
Matched Synonyms: … Interferon alfa-2b ... Interferon alfa-2b (recombinant) ... Interferon alfa-2b, recombinant …
Matched Name: … Interferon alfa-2b …
Matched Description: … A type I interferon consisting of 165 amino acid residues with arginine in position 23. ... This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes …
Matched Mixtures name: … Rebetron Ready To Use Solution (albumin(human)free) (6000000 Iu/ml and 200mg Capsules) …
Matched Categories: … Alfa Interferons ... interferon alfa-2b ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Stratagraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is an allogeneic cellularized scaffold product used for the treatment of adults with thermal burns containing intact dermal elements for which surgical intervention is clinically indicated (also known as deep partial-thickness burns). It was developed as an alternative to autografting...
Approved
Matched Synonyms: … Viable and metabolically active allogeneic human NIKS keratinocytes and human dermal fibroblasts cellularized ... allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat …
Matched Name: … Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen …
Matched Description: … active and viable cells, provide a variety of human growth factors and cytokines as well as extracellular ... Stratagraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is an ... developed as an alternative to autografting - the process by which a patient's own skin is harvested and
Efanesoctocog alfa (BIVV001) is a recombinant factor VIII (FVIII) analogue fusion protein used for the routine prophylaxis, perioperative management of bleeding and on-demand treatment and control of bleeding episodes in patients with hemophilia A. The use of FVIII replacement products is beneficial in patients with hemophilia A; however, their quality...
Approved
Investigational
Matched Name: … Efanesoctocog alfa
Matched Description: … [A257464] Efanesoctocog alfa was designed to have an extended half-life, and to surpass the half-life ... To extend the half-life of FVIII, efanesoctocog alfa is fused to dimeric Fc, a D'D3 domain of VWF, and ... routine prophylaxis, perioperative management of bleeding and on-demand treatment and control of bleeding …
Matched Categories: … Amino Acids, Peptides, and Proteins …
A vitamin-like antioxidant.
Approved
Investigational
Nutraceutical
Matched Synonyms: … Lipoic acid ... Thioctic acid ... α-lipoic acid
Matched Name: … Lipoic acid
Matched Iupac: … 5-[(3R)-1,2-dithiolan-3-yl]pentanoic acid
Matched Categories: … thioctic acid ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products …
Matched Products: … NUTRABIOTICS A-LIPOR ® ACIDO ALFA LIPOICO ... ALPHA LIPOIC ACID CAPSULE ... GNC-ALPHA LIPOIC ACID 100MG …
A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions. Its salts, the salicylates, are used as analgesics.
Approved
Investigational
Vet approved
Matched Synonyms: … Salicylic acid ... 2-Hydroxybenzoic acid ... O-hydroxybenzoic acid
Matched Name: … Salicylic acid
Matched Iupac: … 2-hydroxybenzoic acid
Matched Description: … A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically ... It has bacteriostatic, fungicidal, and keratolytic actions. …
Matched Mixtures name: … Dermaharmony Sulfur and Salicylic Acid ... Dermaharmony Sulfur and Salicylic Acid ... NW SULPHUR 2%W/W AND SALICYLIC ACID 2%W/W CREAM …
Matched Categories: … Salicylic Acid and Derivatives ... salicylic acid ... salicylic acid ... sodium salicylate and methenamine ... Genito Urinary System and Sex Hormones …
Matched Products: … PRICKLY PEAR and SALICYLIC ACID ACNE CLEARING TONIC ... Rosemary and Salicylic Acid Acne Clearing Moisturizer ... Naturopathica Chlorophyll and Salicylic Acid Spot Treatment …
Approved
Matched Name: … Smallpox and Monkeypox Vaccine, Live, Non-replicating …
Approved
Investigational
Matched Synonyms: … Glycollic acid ... 2-Hydroxyacetic acid ... Hydroxyacetic acid
Matched Name: … Glycolic acid
Matched Iupac: … 2-hydroxyacetic acid
Matched Products: … Glycolic Acid
Chenodeoxycholic acid (or Chenodiol) is an epimer of ursodeoxycholic acid (DB01586). Chenodeoxycholic acid is a bile acid naturally found in the body. It works by dissolving the cholesterol that makes gallstones and inhibiting production of cholesterol in the liver and absorption in the intestines, which helps to decrease the formation...
Approved
Matched Synonyms: … Chenic acid ... Chenocholic acid ... Chenodeoxycholic acid
Matched Name: … Chenodeoxycholic acid
Matched Iupac: … 9aS,9bS,11aR)-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid
Matched Description: … Chenodeoxycholic acid is a bile acid naturally found in the body. ... Chenodeoxycholic acid (or Chenodiol) is an epimer of ursodeoxycholic acid (DB01586). ... It works by dissolving the cholesterol that makes gallstones and inhibiting production of cholesterol …
Matched Categories: … Bile Acid Preparations ... chenodeoxycholic acid ... Bile Acids and Salts ... Bile and Liver Therapy ... Bile acids and derivatives …
Matched Products: … Chenodeoxycholic Acid Leadiant …
Tranexamic acid is a synthetic derivative of lysine used as an antifibrinolytic in the treatment and prevention of major bleeding. It possesses a similar mechanism of action to aminocaproic acid but is approximately 10-fold more potent. It was first patented in 1957 and received its initial US approval in 1986.
Approved
Matched Synonyms: … Tranexmic acid ... Tranexamic acid ... Tranhexamic acid
Matched Name: … Tranexamic acid
Matched Iupac: … (1r,4r)-4-(aminomethyl)cyclohexane-1-carboxylic acid
Matched Description: … Tranexamic acid is a synthetic derivative of [lysine] used as an antifibrinolytic in the treatment and ... [L31883] It was first patented in 1957[A230108] and received its initial US approval in 1986. ... It possesses a similar mechanism of action to [aminocaproic acid] but is approximately 10-fold more potent …
Matched Categories: … tranexamic acid ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … Tranexamic acid ... Tranexamic Acid ... TRANEXAMIC ACID
Also known as Aspirin, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. Acetylsalicylic acid has both anti-inflammatory and antipyretic effects. This drug also inhibits platelet aggregation and is used in the prevention of blood clots stroke, and myocardial infarction...
Approved
Vet approved
Matched International brands: … Solprin acid
Matched Synonyms: … 2-Acetoxybenzoic acid ... o-acetoxybenzoic acid ... O-acetylsalicylic acid
Matched Name: … Acetylsalicylic acid
Matched Iupac: … 2-(acetyloxy)benzoic acid
Matched Description: … Acetylsalicylic acid has both anti-inflammatory and antipyretic effects. ... Also known as _Aspirin_, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain ... Acetylsalicylic acid is a very common cause of accidental poisoning in young children. …
Matched Mixtures name: … C T Acetylsalicylic Acid Codeine and Caf Tab ... Acetylsalicylic Acid, Caffeine and 8 Mg Codeine Phosphate ... Clopidogrel/acetylsalicylic Acid Mylan …
Matched Categories: … Salicylic Acid and Derivatives ... codeine and acetylsalicylic acid ... sotalol and acetylsalicylic acid ... oxycodone and acetylsalicylic acid ... bisoprolol and acetylsalicylic acid
Matched Products: … Up and Up Aspirin ... Up and Up aspirin ... Berkley and Jensen Aspirin …
Azelaic acid is a saturated dicarboxylic acid found naturally in wheat, rye, and barley. It is also produced by Malassezia furfur, also known as Pityrosporum ovale, which is a species of fungus that is normally found on human skin. Azelaic acid is effective against a number of skin conditions, such...
Approved
Matched Synonyms: … Anchoic acid ... Azelaic acid ... Lepargylic acid
Matched Name: … Azelaic acid
Matched Iupac: … nonanedioic acid
Matched Description: … Azelaic acid is a saturated dicarboxylic acid found naturally in wheat, rye, and barley. ... It works in part by stopping the growth of skin bacteria that cause acne, and by keeping skin pores clear ... Azelaic acid is effective against a number of skin conditions, such as mild to moderate acne, when applied …
Matched Mixtures name: … Azelaic Acid 15% / Niacinamide 4% ... 2% Salicylic Acid FACIAL CLEANSER …
Matched Categories: … azelaic acid ... Skin and Mucous Membrane Agents …
Matched Products: … Azelaic Acid ... Azelaic Acid Gel …
A common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids.
Approved
Matched Synonyms: … Palmitic Acid ... Hexadecoic acid ... Hexadecylic acid
Matched Name: … Palmitic Acid
Matched Iupac: … hexadecanoic acid
Matched Description: … A common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids. …
Matched Salts name: … 16-chloropalmitic acid
Displaying drugs 1 - 25 of 14930 in total