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Displaying drugs 226 - 250 of 13884 in total

Oseltamivir

Oseltamivir (marketed as the product TamifluⓇ), is an antiviral neuraminidase inhibitor used for the treatment and prophylaxis of infection with influenza viruses A (including pandemic H1N1) and B. Oseltamivir exerts its antiviral activity by inhibiting the activity of the viral neuraminidase enzyme found on the surface of the virus, which...
Approved
Matched Description: … time; there is generally no benefit in use beyond 48 hours for healthy, low-risk individuals as influenza ... They recommend the use of oseltamivir in people with a higher risk of developing complications including ... is a self-limiting illness. …
Matched Categories: … Antivirals for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … Oseltamivir Phosphate for Oral Suspension ... FLUHALT FOR ORAL SUSPENSION 60 mg/ 5 ml ... Oseltamivir Powder for Oral Suspension …

Asparaginase Erwinia chrysanthemi

Asparaginase Erwinia chrysanthemi is an asparaginase-specific enzyme derived from Erwinia chrysanthemi used as an anticancer agent. It works by depleting the stores of an important amino acid called asparagine, which is involved in DNA synthesis and cell survival of malignant cells, leading to cell death. L-asparaginase was first identified in...
Approved
Investigational
Matched Description: … [A236344] Studies show that substitution of _Erwinia_ asparaginase for _E. coli_-derived asparaginase ... patients with acute lymphoblastic leukemia (ALL) who are allergic to _E. coli_-derived asparaginase: ... FDA as a component of a chemotherapy regimen to treat acute lymphoblastic leukemia and lymphoblastic …

Ioxaglic acid

Ioxaglic acid is marketed as Hexabrix. This drug is an ionic tri-iodinated benzoate used as a low-osmolality contrast agent during diagnostic imaging procedures. Like other organic iodine compounds, ioxaglic acid blocks x-rays and is opaque in its appearance on x-ray film, improving the visualization of important structures and organs during...
Approved
Investigational
Matched Description: … Like other organic iodine compounds, ioxaglic acid blocks x-rays and is opaque in its appearance on x-ray ... This drug is an ionic tri-iodinated benzoate used as a low-osmolality contrast agent during diagnostic ... Ioxaglic acid has a low osmolarity and is associated with fewer side effects compared to older contrast …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Gadobutrol

Gadobutrol is a second-generation extracellular non-ionic macrocyclic GBCA (gadolinium-based contrast agent) used in magnetic resonance imaging (MRI) in adults and children older than 2 years of age. Due to its physicochemical properties, gadobutrol is formulated at twice the gadolinium ion concentration compared to other GBCA and thus requires a lesser...
Approved
Matched Description: … agent) used in magnetic resonance imaging (MRI) in adults and children older than 2 years of age. ... Gadobutrol is a second-generation extracellular non-ionic macrocyclic GBCA (gadolinium-based contrast ... fibrosis (NSF) due to the dissociation of gadolinium from the chelates, although gadobutrol tends to have a …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … GADOVIST 1.0 MMOL/ML SOLUTION FOR INJECTION ... Gadograf 1,0 mmol/ml Injektionslösung in Fertigspritzen ... Gadovist 1,0 mmol/ml Injektionslösung in Fertigspritzen/Patronen …

Bisacodyl

Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation.[A233300,L13362] Both bisacodyl and picosulfate are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).[A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956 but has been used as a laxative since 1952.
Approved
Matched Description: … Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional ... A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956[L33045] but has been used as a …
Matched Categories: … Drugs for Constipation …
Matched Products: … Lax-A Go ... Feen-A-mint - Ect 5mg ... Laxative for Women …

Bempedoic acid

High levels of LDL cholesterol (LDL-C) are a major risk factor for cardiovascular events. Caused by genetic mutations or lifestyle factors, hypercholesterolemia can significantly reduce quality of life and increase the risk of mortality from cardiovascular disease. About 1 in 4 patients, or 15 million Americans with elevated LDL-C, are...
Approved
Investigational
Matched Description: … once a day for reducing LDL cholesterol levels in statin-refractory patients. ... High levels of LDL cholesterol (LDL-C) are a major risk factor for cardiovascular events. ... A combination product of bempedoic acid and [ezetimibe] was approved on February 26, 2020 for increased …
Matched Categories: … Hypolipidemic Agents Indicated for Hyperlipidemia ... Non-statin Hypolipidemic Agents Indicated for Hyperlipidemia …

Polyethylene glycol 400

Polyethylene glycols (PEGs) are products made of condensed ethylene oxide and water that can contain various derivatives and have various functions. Because many PEG types are hydrophilic, they are favorably used as enhancers of penetration, and used heavily in topical dermatological preparations. PEGs, along with their many nonionic derivatives, are...
Approved
Matched Description: … In addition, PEG is available as a bowel preparation for colonoscopy procedures and as a laxative [L1788 ... It is used in ophthalmic solutions for the relief of burning, irritation and/or discomfort that follows ... It is very hydrophilic, which renders it a useful ingredient in drug formulations to augment the solubility …
Matched Mixtures name: … Visine ALL DAY COMFORT DRY EYE Relief ... Visine for Red Eye Cool ... Visine for Red Eye Workplace …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Degarelix

Degarelix is used for the treatment of advanced prostate cancer. Degarelix is a synthetic peptide derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and blocks interaction with GnRH. This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately causes testosterone suppression. Reduction in...
Approved
Matched Description: … Degarelix is used for the treatment of advanced prostate cancer. ... Reduction in testosterone is important in treating men with advanced prostate cancer. ... Degarelix is a synthetic peptide derivative drug which binds to gonadotropin-releasing hormone (GnRH) …
Matched Products: … Firmagon 120mg Powder and Solvent for Solution for Injection ... Firmagon 80mg Powder and Solvent for Solution for Injection ... FIRMAGON Powder and Solvent for Solution for Injection 120 mg …

Melatonin

Melatonin is a biogenic amine that is found in animals, plants and microbes. Aaron B. Lerner of Yale University is credited for naming the hormone and for defining its chemical structure in 1958. In mammals, melatonin is produced by the pineal gland. The pineal gland is small endocrine gland, about...
Approved
Nutraceutical
Vet approved
Matched Description: … A 2008 study found that unaffected parents of individuals with ASD also have lower melatonin levels, ... Lerner of Yale University is credited for naming the hormone and for defining its chemical structure ... Melatonin is a biogenic amine that is found in animals, plants and microbes. Aaron B. …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Human interferon beta

Human interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis (MS), and was initially approved by the FDA in 1992. Multiple Sclerosis is a devastating neurodegenerative disease that is usually progressive and significantly debilitating with a profound impact on the quality of life. Interferon...
Approved
Investigational
Matched Description: … It is therefore a potential drug candidate for SARS-CoV-2 based on viral genetic similarity. ... [A191784] Interferon beta is currently being studied as a possible treatment for COVID-19, which ... Human interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis …
Matched Categories: … Experimental Unapproved Treatments for COVID-19 …

Ixekizumab

Ixekizumab is a humanized immunoglobulin G subclass 4 (IgG4) monoclonal antibody (mAb) against interleukin-17A (IL-17A) and prevents it from interacting with the IL-17A receptor. As IL-17A is a pro-inflammatory cytokine involved in inflammation and immune responses, blocking its effect is beneficial for use in inflammatory conditions. In particular, IL-17A has...
Approved
Investigational
Matched Description: … effect is beneficial for use in inflammatory conditions. ... In particular, IL-17A has been found to be implicated in a variety of autoimmune diseases including Rheumatoid ... As IL-17A is a pro-inflammatory cytokine involved in inflammation and immune responses, blocking its …
Matched Products: … Taltz 80mg solution for injection in pre-filled pen ... Taltz 80mg solution for injection in pre-filled syringe ... TALTZ SOLUTION FOR INJECTION IN PRE-FILLED PEN 80 mg/ml …

Soybean oil

Derived from soybeans, soybean oil is a common vegetable oil and a source of polyunsaturated and saturated fatty acids. It is a complex mixture of triglycerides where per 100 g, soybean oil has 16 g of saturated fat, 23 g of monounsaturated fat, and 58 g of polyunsaturated fat. The...
Approved
Matched Description: … It is used as a cooking oil and lipid emulsion for parenteral nutrition in clinical settings. ... Derived from soybeans, soybean oil is a common vegetable oil and a source of polyunsaturated and saturated ... Soybean oil-based lipid emulsion is the only FDA-approved lipid formulation for clinical use. …
Matched Mixtures name: … KABIVEN EMULSION FOR INFUSION ... OLIMEL N7E, emulsion for infusion ... OLIMEL N9E, emulsion for infusion …

Remdesivir

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19), which is a respiratory disease that is capable of progressing to viral pneumonia and acute respiratory distress syndrome (ARDS); COVID-19 can be fatal. Like other RNA viruses, SARS-CoV-2 depends on an RNA-dependent RNA polymerase...
Approved
Investigational
Matched Description: … in 2016 as a potential treatment for Ebola. ... ] leading to considerable interest in remdesivir as a possible treatment for COVID-19. ... [L39640] Remdesivir in combination with [baricitinib] for the treatment of COVID-19, was granted an FDA …
Matched Categories: … Antivirals for Systemic Use ... Antiinfectives for Systemic Use ... Approved Treatments for COVID-19 …
Matched Products: … COVIFOR (REMDESIVIR FOR INJECTION 100MG/VIAL) ... VEKLURY® LYOPHILIZED POWDER FOR IV INFUSION 100MG/VIAL …

Secnidazole

Secnidazole is a second-generation 5-nitroimidazole antimicrobial agent. It is structurally related to other 5-nitroimidazoles, including DB00916 and DB00911, but displays improved oral absorption and a longer terminal elimination half-life than other drugs in this class. Secnidazole is selective against many anaerobic Gram-positive and Gram-negative bacteria as well as protozoa. Once...
Approved
Matched Description: … [A245503, A245508] In September 2017, FDA approved secnidazole under the market name Solosec for the ... Africa for decades. ... [A245503] Secnidazole has been available in many other countries in Europe, Asia, South America, and …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … SECNICHEN POLVO PARA RECONSTITUIR A SUSPENSIÓN ORAL ... SECNIDAZOL PPS (POLVO PARA RECONSTITUIR A SUSPENSIÓN) ... SECNIPEN 750 MG POLVO PARA RECOSTRUIR A SUSPENSION ORAL …

Pegunigalsidase alfa

Pegunigalsidase alfa (PRX-102) is a recombinant form of human α-galactosidase-A indicated for long-term enzyme replacement therapy in patients with Fabry disease, a rare genetic disorder characterized by the deficiency of alpha-galactosidase A.[A259352,L46342] Unlike other forms of recombinant alpha-galactosidase A, such as agalsidase alfa and agalsidase beta, pegunigalsidase alfa uses a...
Approved
Investigational
Matched Description: … Pegunigalsidase alfa (PRX-102) is a recombinant form of human α-galactosidase-A indicated for long-term ... enzyme replacement therapy in patients with Fabry disease, a rare genetic disorder characterized by ... [A259347,A259352] In May 2023, the EMA granted marketing authorization to pegunigalsidase alfa in …

Technetium Tc-99m disofenin

Technetium Tc-99m disofenin is a radiopharmaceutical agent used in hepatobiliary imaging for diagnostic purposes. It is well suited for both planar and single photon tomographic scintigraphy to quantitatively measure the function of liver, gallbladder and bile ducts and detect any anatomical changes in the hepatobliary system. It is available as...
Approved
Matched Description: … Technetium Tc-99m disofenin is a radiopharmaceutical agent used in hepatobiliary imaging for diagnostic ... and its hepatic uptake is not as highly dependent on serum bilirubin levels (a competitive inhibitor ... It is available as an intravenous injection in a preparation kit under the name Hepatolite. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Kit for the Preparation of Technetium Tc99m Disofenin …

Rotavirus vaccine

Rotavirus commonly infects children and infants causing severe diarrhea and vomiting leading to potentially fatal dehydration. Two rotavirus vaccines are available for the prevention of rotavirus gastroenteritis, Rotateq and Rotarix. Rotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains. Rotarix is a live attenuated vaccine containing the...
Approved
Matched Description: … [Label] Rotavirus vaccines are 90% effective in protecting against severe rotavirus infection. ... [L1117] Two rotavirus vaccines are available for the prevention of rotavirus gastroenteritis, Rotateq ... Rotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains. …
Matched Salts name: … Human Rotavirus A type G1P(8) strain RIX4414 live antigen ... Human Rotavirus A type G1P7(5) strain WI79 live antigen ... Human Rotavirus A type G2P7(5) strain SC2 live antigen ... Human Rotavirus A type G4P7(5) strain BRB live antigen ... Human Rotavirus A type G3P7(5) strain WI78 live antigen …
Matched Categories: … Antiinfectives for Systemic Use …

Linoleic acid

Approved
Experimental
Matched Synonyms: … all-cis-9,12-octadecadienoic acid …

Labetalol

Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up 25% of the mixture. Labetalol is formulated as an injection or tablets to treat hypertension.[L7727,L7730] Labetalol was granted FDA approval on 1 August 1984.
Approved
Matched Description: … Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up …
Matched Categories: … Antihypertensive Agents Indicated for Hypertension …
Matched Products: … Labetalol HCl in Dextrose ... Labetalol HCl in Sodium Chloride ... BLOCAMINE (Labetalol hydrochloride 5 mg/ml solution for Injection and for Infusion) …

Terlipressin

Terlipressin is a synthetic analogue of vasopressin, which is an endogenous neurohormone that acts as a vasoconstrictor. It is a prodrug of lypressin, or lysine vasopressin. Compared to endogenous vasopressin, terlipressin has a longer half life and increased selectivity for the V1 receptor. As a potent vasopressor, terlipressin has been...
Approved
Investigational
Matched Description: … Compared to endogenous vasopressin, terlipressin has a longer half life and increased selectivity for ... [L43217] As a potent vasopressor, terlipressin has been investigated in various shock states and conditions ... a vasoconstrictor. …
Matched Products: … GLYPRESSIN FOR INJECTION 1 mg/vial ... GLYPRESSIN 1mg/8.5ml solution for injection ... GLYPRESSIN solution for injection, 1 mg/8.5 ml …

Abatacept

Abatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin G1 (IgG1).[L20504,L42715] Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it...
Approved
Matched Description: … Although approved for the treatment of rheumatoid arthritis, Repligen has entered a slightly different ... It is produced through recombinant DNA technology in mammalian CHO cells. ... [L20504,L42715] Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight …
Matched Categories: … Agents reducing cytokine levels ... Biologics for Rheumatoid Arthritis Treatment …
Matched Products: … ORENCIA Injection 125mg/ml in Prefilled Syringe …

Emicizumab

Emicizumab is a humanized recombinant monoclonal antibody that mimics the function of the coagulation Factor VIII and it has the capacity to bind simultaneously to activated Factor IX and Factor X. The ability of Emicizumab to bind to all these three different factors allows it to overcome immunogenicity and unstable...
Approved
Investigational
Matched Description: … Emicizumab is a humanized recombinant monoclonal antibody that mimics the function of the coagulation ... The ability of Emicizumab to bind to all these three different factors allows it to overcome immunogenicity …
Matched Products: … HEMLIBRA 30MG/ML SOLUTION FOR INJECTION ... HEMLIBRA 150MG/ML SOLUTION FOR INJECTION ... HEMLIBRA SOLUTION FOR INJECTION 30MG/ML …

Flurbiprofen

Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen may also be used topically prior to ocular surgery to prevent or reduce intraoperative miosis....
Approved
Investigational
Matched Description: … Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic ... Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, …
Matched Categories: … Topical Products for Joint and Muscular Pain ... Antiinflammatory Preparations, Non-Steroids for Topical Use …
Matched Products: … STREPSILS INTENSIVE SOLUCION EN SPRAY SABOR A MIEL Y LIMON ... Strepsils 8,75 mg/Dosis Spray zur Anwendung in der Mundhöhle, Lösung ... Strepsils Honig & Zitrone 8,75 mg/Dosis Spray zur Anwendung in der Mundhöhle, Lösung …

Strontium ranelate

Strontium ranelate, a strontium (II) salt of ranelic acid, is a medication for osteoporosis. Some reports have shown that strontium ranelate can slow down the progression of osteoarthritis of the knee. This agent presents an atypical mechanism of action in which it increases deposition of new bone by osteoblasts and,...
Approved
Withdrawn
Matched Description: … Available for prescription use for a time in some parts of the world as Protelos (strontium ranelate) ... It is therefore promoted as a "dual action bone agent" (DABA) indicated for use in treatment of severe ... Strontium ranelate, a strontium (II) salt of ranelic acid, is a medication for osteoporosis. …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Matched Products: … PROTOS Granules for Oral Suspension 2g …

Oxybutynin

Overactive bladder (OAB) is a common condition negatively impacting the lives of millions of patients worldwide. Due to its urinary symptoms that include nocturia, urgency, and frequency, this condition causes social embarrassment and a poor quality of life.[A185996,A185999] Oxybutynin, also marketed as Ditropan XL, is an anticholinergic medication used for...
Approved
Investigational
Matched Description: … the relief of overactive bladder symptoms that has been optimized for high levels of safety and efficacy ... since initial FDA approval in 1975. ... Overactive bladder (OAB) is a common condition negatively impacting the lives of millions of patients …
Matched Categories: … Drugs for Urinary Frequency and Incontinence …
Matched Products: … Oxytrol For Women ... Oxytrol for Women …
Displaying drugs 226 - 250 of 13884 in total