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Displaying drugs 226 - 250 of 13436 in total

Leuprolide

Leuprolide is a synthetic 9-residue peptide analogue of gonadotropin-releasing hormone (GnRH). Unlike the endogenous decapeptide GnRH, leuprolide contains a single D-amino acid (D-leucyl) residue, which helps to increase its circulating half-life from three to four minutes to approximately three hours. As a GnRH mimic, leuprolide is capable of binding to...
Approved
Investigational
Matched Iupac: … (2S)-1-[(2S)-5-carbamimidamido-2-[(2S)-2-[(2R)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol …
Matched Description: … Leuprolide is a synthetic 9-residue peptide analogue of gonadotropin-releasing hormone (GnRH). ... Unlike the endogenous decapeptide GnRH, leuprolide contains a single D-amino acid (D-leucyl) residue, ... [A203222] As a GnRH mimic, leuprolide is capable of binding to the GnRH receptor (GnRHR) and inducing …
Matched Products: … LUPRON ® DEPOT 11.25 MG POLVO LIOFILIOZADO PARA RECONSTITUIR A SUSPENSIÓN INYECTABLE ... LEUPRONE 5 MG IMPLANT, 1 ADET ... LEUPRONE 3.6 MG IMPLANT, 1 ADET …

Sulfamethazine

A sulfanilamide anti-infective agent. It has a spectrum of antimicrobial action similar to other sulfonamides.
Approved
Investigational
Vet approved
Matched Synonyms: … N(1)-(4,6-Dimethyl-2-pyrimidyl)sulfanilamide ... N(1)-(4,6-Dimethyl-2-pyrimidinyl)sulfanilamide …
Matched Iupac: … 4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzene-1-sulfonamide …
Matched Description: … A sulfanilamide anti-infective agent. ... It has a spectrum of antimicrobial action similar to other sulfonamides. …

Progesterone

Progesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity, embryo implantation, and the successful establishment of pregnancy. A low progesterone concentration or an insufficient response to progesterone can cause infertility and pregnancy loss . Progesterone is used in various contraceptive preparations to prevent ovulation...
Approved
Vet approved
Matched Iupac: … [a]phenanthren-7-one ... (1S,3aS,3bS,9aR,9bS,11aS)-1-acetyl-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta …
Matched Description: … Pharmaceutical progesterone is made from a plant source as a starting material and is chemically identical ... Progesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity ... A low progesterone concentration or an insufficient response to progesterone can cause infertility and …
Matched Products: … N/A ... PROGESTOGEL 1% ... PROGYNEX % 1 JEL, 80 G …

Nonoxynol-9

Nonoxynol-9 (N-9) is a typical surfactant used as a vaginal spermicide. Spermicides are locally acting non-hormonal contraceptives. When present in the vagina during intercourse, they immobilize/inactivate/damage and/or kill sperms without eliciting systemic effects. N-9 has been in use for more than 30 years as an over-the-counter (OTC) drug in creams,...
Approved
Withdrawn
Matched Synonyms: … 26-(Nonylphenoxy)-3,6,9,12,15,18,21,24-octaoxahexacosan-1-ol …
Matched Iupac: … 26-(4-nonylphenoxy)-3,6,9,12,15,18,21,24-octaoxahexacosan-1-ol …
Matched Description: … Nonoxynol-9 (N-9) is a typical surfactant used as a vaginal spermicide. …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Ensulizole

Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that absorbs strongly at UV-B wavelengths. It is commonly found in cosmetic products and sunscreen formulas in combination with other UV filter compounds due to its minimal protection against UV-A wavelengths. Due to its water solubility, ensulizole is commonly...
Approved
Matched Description: … Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that ... cyclobutane pyrimidine dimers and photosensitized the formation of oxidized guanine bases after UV-A ... sunscreen formulas in combination with other UV filter compounds due to its minimal protection against UV-A …
Matched Mixtures name: … Aqua Fusion SPF 15 Peau Normale A Seche ... Careone Anti Aging Vitamin Complex 7 in 1 ... Happyderm SPF 15 Peaux Normales A Seches …
Matched Products: … Covergirl Outlast All Day Stay Fabulous 3-IN-1 Foundation ... Full Spectrum Matte Ambition Skin Primer SPF 20 ... Covergirl TruBlend Base Business Everyday Defense Primer SPF 20 …

Dicoumarol

Dicoumarol is an oral anticoagulant agent that works by interfering with the metabolism of vitamin K. In addition to its clinical use, it is also used in biochemical experiments as an inhibitor of reductases.
Approved
Matched Synonyms: … 3,3'-methylenebis(4-hydroxy-2H-1-benzopyran-2-one) …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index …

Ergotamine

A vasoconstrictor found in ergot of Central Europe. It is an alpha-1 selective adrenergic agonist and is commonly used in the treatment of migraine disorders.
Approved
Matched Iupac: … diazatricyclo[7.3.0.0^{2,6}]dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1( …
Matched Description: … A vasoconstrictor found in ergot of Central Europe. ... It is an alpha-1 selective adrenergic agonist and is commonly used in the treatment of migraine disorders …
Matched Mixtures name: … ERGO SANOL DRAJE , 20 ADET ... AVMIGRAN FİLM TABLET, 20 ADET ... ERGOTAMINA/CAFEINA 1/100 MG …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Products: … ERGAFEIN DRAJE, 20 ADET …

Milrinone

Heart failure is a multifactorial condition that affects roughly 1-2% of the adult population. Often the result of long-term myocardial ischemia, cardiomyopathy, or other cardiac insults, heart failure results from an inability of the heart to perfuse peripheral tissues with sufficient oxygen and metabolites, resulting in complex systemic pathologies. Heart...
Approved
Matched Description: … Heart failure is a multifactorial condition that affects roughly 1-2% of the adult population. ... [A228323] Milrinone is a second-generation bipyridine phosphodiesterase (PDE) inhibitor created through ... [A228333] As a PDE-III inhibitor, milrinone results in increased cAMP levels and improves cardiac function …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Compounds used in a research, industrial, or household setting …
Matched Products: … MULTİFLEKS KARDİYOMİL 20 MG/100 ML IV İNFÜZYONLUK ÇÖZELTİ ... Milrinon Hikma 1 mg/ml Injektionslösung ... Milrinon Tillomed 1 mg/ml Injektions-/Infusionslösung …

Tacrolimus

Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug whose main use is after organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It is also used in a topical preparation in the treatment of severe atopic dermatitis, severe refractory uveitis...
Approved
Investigational
Matched Iupac: … ]prop-1-en-2-yl]-23,25-dimethoxy-13,19,21,27-tetramethyl-17-(prop-2-en-1-yl)-11,28-dioxa-4-azatricyclo ... (1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-1,14-dihydroxy-12-[(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl …
Matched Description: … Tacrolimus is chemically known as a macrolide. ... It is also used in a topical preparation in the treatment of severe atopic dermatitis, severe refractory ... It was discovered in 1984 from the fermentation broth of a Japanese soil sample that contained the bacteria …
Matched Mixtures name: … Hyaluronic Acid Sodium Salt 1% / Tacrolimus 0.1% / Urea 20% ... Hyaluronic Acid Sodium Salt 1% / Niacinamide 4% / Tacrolimus 0.1% …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index …
Matched Products: … TACROCIN 1- TACROLIMUS CAPSULE USP 1 MG ... TACLIM 1 MG ... ADVAGRAF(R) 1 MG …

Estradiol valerate

Estradiol Valerate (also known as E2V) is a pro-drug ester of DB00783, a naturally occurring hormone that circulates endogenously within the human body. Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex hormone. As a pro-drug of estradiol, estradiol acetate therefore...
Approved
Investigational
Vet approved
Matched Iupac: … -1-yl pentanoate ... (1S,3aS,3bR,9bS,11aS)-7-hydroxy-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthren …
Matched Description: … Estradiol Valerate (also known as E2V) is a pro-drug ester of [DB00783], a naturally occurring hormone ... As a pro-drug of estradiol, estradiol acetate therefore has the same downstream effects within the body ... First-pass metabolism by the gut and the liver quickly degrades the estradiol molecule before it gets a …
Matched Mixtures name: … VELBIENNE® 20 ... VELBIENNE® 20 ... DIVICONT TABLETAS 1 MG/5 MG …
Matched Products: … โปรกีโนวา 1 มก. ... PROGYNOVA 1 MG. ... MERIESTRA ® 1 MG …

Ziprasidone

Disorders such as schizophrenia and bipolar disorder can significantly impair mood, cognition, and behavior. These mental illnesses can often be accompanied by comorbidities such as depression and substance abuse, and can significantly impact the quality of life of patients and caregivers. Luckily, several treatment options for psychotic disorders have been...
Approved
Matched Iupac: … 5-{2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl}-6-chloro-2,3-dihydro-1H-indol-2-one …
Matched Description: … [A180748] Although ziprasidone is classified as an atypical antipsychotic, it appears to have a lower …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists ... Heterocyclic Compounds, 1-Ring …
Matched Products: … ICIN KURU TOZ ICEREN FLAKON 20MG/ML FLAKON, 1 ADET ... ZIPROS 20 ... ZELDOX 20 MG …

Bendamustine

Bendamustine is a nitrogen mustard drug which has been used in the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL). Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl groups that covalently bond to other molecules. Through this function as an alkylating agent, bendamustine...
Approved
Investigational
Matched Iupac: … 4-{5-[bis(2-chloroethyl)amino]-1-methyl-1H-1,3-benzodiazol-2-yl}butanoic acid …
Matched Description: … Bendamustine is a nitrogen mustard drug which has been used in the treatment of chronic lymphocytic leukemia ... Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl groups …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index …
Matched Products: … LEVACT 25 MG İNFÜZYONLUK ÇÖZELTİ İÇİN TOZ İÇEREN FLAKON , 20 ADET ... GENSTINA® POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE ... INFÜZYON IÇIN LIYOFILIZE TOZ IÇEREN FLAKON ,1 ADET …

Influenza A virus A/Christchurch/16/2010 NIB-74XP (H1N1) antigen (formaldehyde inactivated)

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Synonyms: … influenza A virus A/Christchurch/16/2010 (H1N1) antigen …
Matched Name: … Influenza A virus A/Christchurch/16/2010 NIB-74XP (H1N1) antigen (formaldehyde inactivated) …
Matched Description: … A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …

Tetracycline

Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria. It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and blocking incoming aminoacyl tRNA from binding to the ribosome acceptor site. It also binds to some extent to the...
Approved
Vet approved
Withdrawn
Matched Description: … Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria ... It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit ... for the use of all liquid oral drug products formulated for pediatric use containing tetracycline in a …
Matched Products: … Tetracycline 3 percent a First Aid Antibiotic ... Achromycin Ont Oph 1% ... Tetracycline 1% Ophthalmic Ointment …

Ketoconazole

Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal infections.[FDA Label] It functions by preventing the synthesis of ergosterol, the fungal equivalent of cholesterol, thereby increasing membrane fluidity and preventing growth of the fungus.[A181802,T116] Ketoconazole was first approved in an oral formulation...
Approved
Investigational
Matched Iupac: … -1-yl]ethan-1-one ... 1-[4-(4-{[2-(2,4-dichlorophenyl)-2-[(1H-imidazol-1-yl)methyl]-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin …
Matched Description: … Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal ... [A188054] At this time it was considered a significant improvement over previous antifungals, [miconazole …
Matched Mixtures name: … Hydrocortisone 2.5% / Iodoquinol 1% / Ketoconazole 2% …
Matched Products: … Nizoral A-D ... A-BE LOTION ... NIZORAL SHAMPOO 20 mg/g …

Degarelix

Degarelix is used for the treatment of advanced prostate cancer. Degarelix is a synthetic peptide derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and blocks interaction with GnRH. This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately causes testosterone suppression. Reduction in...
Approved
Matched Iupac: … (4S)-N-{4-[(2S)-2-{[(1R)-2-[4-(carbamoylamino)phenyl]-1-{[(1S)-1-{[(2S)-1-[(2S)-2-{[(1R)-1-carbamoylethyl ... ]carbamoyl}pyrrolidin-1-yl]-1-oxo-6-[(propan-2-yl)amino]hexan-2-yl]carbamoyl}-3-methylbutyl]carbamoyl …
Matched Description: … Degarelix is a synthetic peptide derivative drug which binds to gonadotropin-releasing hormone (GnRH) ... Chemically, it is a synthetic linear decapeptide amide with seven unnatural amino acids, five of which …

Benzphetamine

A sympathomimetic agent with properties similar to dextroamphetamine. It is used in the treatment of obesity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1222)
Approved
Illicit
Matched Synonyms: … N-methyl-1-phenyl-N-(phenylmethyl)propan-2-amine …
Matched Iupac: … benzyl(methyl)[(2S)-1-phenylpropan-2-yl]amine …
Matched Description: … A sympathomimetic agent with properties similar to dextroamphetamine. …
Matched Categories: … Adrenergic alpha-1 Receptor Agonists …

Medroxyprogesterone acetate

Medroxyprogesterone acetate (MPA) is a progesterone derivative that is more resistant to metabolism for improved pharmacokinetic properties. MPA can be use to treat secondary amenorrhea, endometrial hyperplasia, abnormal uterine bleeding, osteoporosis, vasomotor symptoms in menopause, vulvar and vaginal atrophy, prevent pregnancy, manage pain in endometriosis, prevent pregnancy, and is also...
Approved
Investigational
Matched Iupac: … ,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl acetate ... (1R,3aS,3bR,5S,9aR,9bS,11aS)-1-acetyl-5,9a,11a-trimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH …
Matched Description: … Medroxyprogesterone acetate (MPA) is a [progesterone] derivative that is more resistant to metabolism …
Matched Mixtures name: … DIVICONT TABLETAS 1 MG/5 MG ... DIVICONT TABLETAS 1 MG/2.5 MG …
Matched Products: … อีนาฟ-150 (1 มล.) ... OBAT SUNTIK KB 1 TIGA BULANAN ... FARLUTAL 500 MG FLAKON, 1 ADET …

Potassium chloride

A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives. The FDA withdrew its approval for the use of all solid oral dosage form drug products containing potassium chloride that supply 100 mg or more of...
Approved
Withdrawn
Matched Description: … A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia …
Matched Mixtures name: … Plasma-Lyte A ... Elliott's Solution A ... MULTIELECTROLITOS TIPO 1 …
Matched Products: … Kcl Solution A 20% ... Kaochlor-20 ... CLORURO DE POTASIO 20 MEQ/10 ML …

Cobimetinib

Cobimetinib is an orally active, potent and highly selective small molecule inhibiting mitogen-activated protein kinase kinase 1 (MAP2K1 or MEK1), and central components of the RAS/RAF/MEK/ERK signal transduction pathway. It has been approved in Switzerland and the US, in combination with vemurafenib for the treatment of patients with unresectable or...
Approved
Investigational
Matched Iupac: … 1-{3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzoyl}-3-[(2S)-piperidin-2-yl]azetidin-3-ol …
Matched Description: … active, potent and highly selective small molecule inhibiting mitogen-activated protein kinase kinase 1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... MAP Kinase Kinase 1, antagonists & inhibitors ... UGT2B7 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Products: … COTELLIC FILM-COATED TABLET 20 MG ... COTELLIC® (COBIMETINIB) 20 MG TABLETAS RECUBIERTAS ... COTELLIC 20 MG FILM KAPLI TABLET,63 FILM KAPLI TABLET …

Histrelin

Histrelin is a gonadotropin-releasing hormone (GnRH) agonist that acts as a potent inhibitor of gonadotropin when administered as an implant delivering continuous therapeutic doses. This drug is a synthetic analog of naturally occurring GnRH with a higher potency. Histrelin implants are non-biodegradable, diffusion-controlled, hydrogel polymer reservoirs containing histrelin acetate that...
Approved
Withdrawn
Matched Synonyms: … 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-1-benzyl-D-histidyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide …
Matched Iupac: … (2S)-1-[(2S)-2-[(2S)-2-[(2R)-3-(1-benzyl-1H-imidazol-4-yl)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)- …
Matched Description: … This drug is a synthetic analog of naturally occurring GnRH with a higher potency. ... Histrelin is a gonadotropin-releasing hormone (GnRH) agonist that acts as a potent inhibitor of gonadotropin …

Influenza B virus B/Austria/1359417/2021 live (attenuated) antigen

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Description: … A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …

Oxolamine

Oxolamine is not approved in the USA, it may be marketed elsewhere internationally as a cough suppressant . It is listed as a prescription drug in New Zealand legislation . Oxolamine is also approved in Taiwan for the treatment of respiratory tract inflamation .
Approved
Matched Description: … It is listed as a prescription drug in New Zealand legislation [L5419]. ... Oxolamine is not approved in the USA, it may be marketed elsewhere internationally as a cough suppressant …
Matched Salts cas: … 1949-20-8 …
Matched Mixtures name: … KATARIN 120 MG+50 MG+1 MG/5 ML PEDIATRIK SURUP 100 ML ... KATARIN FORT 650 MG/200 MG/60 MG/4 MG FİLM KAPLI TABLET, 20 ADET …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … SEKODIN 0,2 GR TABLET, 20 ADET …

Thiosulfuric acid

Thiosulfuric acid is available in its salt forms sodium thiosulfate and sodium thiosulfate pentahydrate. Sodium thiosulfate is part of the World Health Organization’s list of essential medicines, and it has a variety of industrial uses, including food preservative, water de-chlorinator and paper pulp bleaching agent. Sodium thiosulfate is rapidly degraded...
Approved
Investigational
Matched Iupac: … dihydroxy-1lambda6-disulfen-1-one …
Matched Description: … Sodium thiosulfate is part of the World Health Organization’s list of essential medicines, and it has a ... [L43337] When administered 6 hours after cisplatin chemotherapy, Sodium thiosulfate leads to a lower ... cyanide poisoning[L310,L43332,A252832] and it is frequently used in conjunction with sodium nitrite (a …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … TIOSULFATO DE SODIO 20% …

Rotavirus vaccine

Rotavirus commonly infects children and infants causing severe diarrhea and vomiting leading to potentially fatal dehydration. Two rotavirus vaccines are available for the prevention of rotavirus gastroenteritis, Rotateq and Rotarix. Rotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains. Rotarix is a live attenuated vaccine containing the...
Approved
Matched Description: … Rotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains. ... [L1116] Rotarix is a live attenuated vaccine containing the 89-12 human strain. …
Matched Salts name: … Human Rotavirus A type G1P(8) strain RIX4414 live antigen ... Human Rotavirus A type G1P7(5) strain WI79 live antigen ... Human Rotavirus A type G2P7(5) strain SC2 live antigen ... Human Rotavirus A type G4P7(5) strain BRB live antigen ... Human Rotavirus A type G3P7(5) strain WI78 live antigen …
Matched Products: … ROTARIX ORAL SÜSPANSIYON HAZIRLAMAK IÇIN LIYOFILIZE TOZ IÇEREN FLAKON, 1 ADET …
Displaying drugs 226 - 250 of 13436 in total