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Displaying drugs 226 - 250 of 14523 in total

Digoxin

Digoxin is one of the oldest cardiovascular medications used today. It is a common agent used to manage atrial fibrillation and the symptoms of heart failure. Digoxin is classified as a cardiac glycoside and was initially approved by the FDA in 1954. This drug originates from the foxglove plant, also...
Approved
Matched Description: … [A178225] It is a common agent used to manage atrial fibrillation and the symptoms of heart failure. ... [A178234] Digoxin is classified as a cardiac glycoside and was initially approved by the FDA in 1954. ... plant, also known as the _Digitalis_ plant[T610], studied by William Withering, an English physician and …
Matched Categories: … Digoxin and derivatives …

Tolvaptan

Tolvaptan is used to treat low blood sodium levels (hyponatremia) associated with various conditions like congestive heart failure, cirrhosis, and syndrome of inappropriate antidiuretic hormones (SIADH). FDA approved on May 19, 2009.
Approved
Matched Description: … Tolvaptan is used to treat low blood sodium levels (hyponatremia) associated with various conditions ... like congestive heart failure, cirrhosis, and syndrome of inappropriate antidiuretic hormones (SIADH) …
Matched Categories: … Antidiuretic Hormone Receptor Antagonists …

Darolutamide

Darolutamide is a nonsteroidal androgen receptor antagonist for the treatment of castrate-resistant, non-metastatic prostate cancer (nmCRPC). This condition occurs in the majority of patients with advanced prostate cancer who have been treated with androgen receptor antagonists. Though prior treatment for prostate cancer has been successful for these patients, the cancer...
Approved
Investigational
Matched Description: … [A189054,A189063] Darolutamide was developed by Bayer HealthCare Pharmaceuticals Inc. and approved by ... darolutamide is to delay the progression of prostate cancer to metastatic disease, increasing quality of life and …
Matched Categories: … Hormone Antagonists and Related Agents ... Antineoplastic and Immunomodulating Agents …

Nitrendipine

Nitrendipine is a calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
Approved
Investigational
Matched Description: … does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive. ... It is an effective antihypertensive agent and differs from other calcium channel blockers in that it …
Matched Categories: … enalapril and nitrendipine ... ACE Inhibitors and Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents …

Insulin degludec

Insulin degludec is an ultra-long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.[A18561,A18562,A18563,A18564,A174934] Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone ... tissues such as the liver, fat cells, and skeletal muscle. ... inhibits lipolysis and proteolysis among many other functions. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin degludec and liraglutide ... insulin degludec and insulin aspart …

Enoxaparin

Enoxaparin is a common low-molecular-weight heparin (LMWH) used in the prevention and management of various thromboembolic disorders. Initially approved by the FDA in 1993, it is administered by a subcutaneous or intravenous injection and marketed by several pharmaceutical companies. Enoxaparin markedly reduces the incidence of venous thromboembolism in hospitalized patients...
Approved
Matched Description: … Enoxaparin is a common low-molecular-weight heparin (LMWH) used in the prevention and management of various ... Initially approved by the FDA in 1993, it is administered by a subcutaneous or intravenous injection and …
Matched Salts name: … Enoxaparin sodium …
Matched Categories: … Heparin and similars ... Blood and Blood Forming Organs …
Matched Products: … Enoxaparin Sodium ... Enoxaparin sodium ... ENOXAPARIN SODIUM INJECTION CUTENOX INJEKTA PFS40 MG/0.4 ML …

Angiotensin II

Angiotensin II is under investigation for the treatment of Sepsis, Septic Shock, Diabetes Mellitus, and Acute Renal Failure. Angiotensin II has been investigated for the treatment, basic science, and diagnostic of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Nephropathy. As of December 21, 2017 the FDA approved La Jolla Pharmaceutical's...
Approved
Investigational
Matched Description: … and death within hours, no matter young or o ld. ... , Renin Angiotensin System, and Idiopathic Membranous Nephropathy. ... Angiotensin II is under investigation for the treatment of Sepsis, Septic Shock, Diabetes Mellitus, and …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Amino Acids, Peptides, and Proteins …

Lormetazepam

Lormatazepam is an orally available benzodiazepine used in the UK for the treatment of short-term insomnia . It is marketed by Auden Mckenzie (Pharma Division) in 0.5 and 1 mg tablet formulations.
Approved
Matched Description: … It is marketed by Auden Mckenzie (Pharma Division) in 0.5 and 1 mg tablet formulations. …
Matched Categories: … Hypnotics and Sedatives ... Benzodiazepines and benzodiazepine derivatives …

Letrozole

Letrozole, or CGS 20267, is an oral non-steroidal type II aromatase inhibitor first described in the literature in 1990.[A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like exemestane and anastrozole, meaning it does not significantly affect cortisol, aldosterone, and thyroxine. Letrozole was granted FDA approval on 25 July 1997.
Approved
Investigational
Matched Description: … ], meaning it does not significantly affect cortisol, aldosterone, and thyroxine. ... [A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like [exemestane] and [anastrozole …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Hormone Antagonists and Related Agents ... Antineoplastic and Immunomodulating Agents ... Hormone Antagonists …

Cholic Acid

A major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. [PubChem] Cholic acid, formulated as Cholbam capsules, is approved by the United States Food and Drug Administration as a treatment for children and adults with bile acid...
Approved
Matched Description: … It facilitates fat absorption and cholesterol excretion. ... enzyme defects, and for peroxisomal disorders (such as Zellweger syndrome). ... A major primary bile acid produced in the liver and usually conjugated with glycine or taurine. …
Matched Categories: … Bile Acids and Salts ... Bile and Liver Therapy ... Bile acids and derivatives ... Alimentary Tract and Metabolism …

Chenodeoxycholic acid

Chenodeoxycholic acid (or Chenodiol) is an epimer of ursodeoxycholic acid (DB01586). Chenodeoxycholic acid is a bile acid naturally found in the body. It works by dissolving the cholesterol that makes gallstones and inhibiting production of cholesterol in the liver and absorption in the intestines, which helps to decrease the formation...
Approved
Matched Description: … It works by dissolving the cholesterol that makes gallstones and inhibiting production of cholesterol ... in the liver and absorption in the intestines, which helps to decrease the formation of gallstones. …
Matched Categories: … Bile Acids and Salts ... Bile and Liver Therapy ... Bile acids and derivatives ... Alimentary Tract and Metabolism …

Estramustine

A nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also has radiation protective properties.
Approved
Investigational
Matched Salts name: … Estramustin sodium phosphate …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Rimonabant

Rimonabant is an anorectic anti-obesity drug produced and marketed by Sanofi-Aventis. It is an inverse agonist for the cannabinoid receptor CB1. Its main avenue of effect is reduction in appetite. Rimonabant is the first selective CB1 receptor blocker to be approved for use anywhere in the world. Rimonabant is approved...
Approved
Investigational
Matched Description: … Rimonabant is an anorectic anti-obesity drug produced and marketed by Sanofi-Aventis. ... Rimonabant is approved in 38 countries including the E.U., Mexico, and Brazil. ... . advisory panel recommended the medicine not be approved because it may increase suicidal thinking and …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Cannabinoids and similars ... Alimentary Tract and Metabolism …

Bremelanotide

Bremelanotide is a 7 amino acid peptide used to treat hypoactive sexual desire disorder in premenopausal women. Bremelanotide does not interact with alcohol. The mechanism by which bremelanotide's action on receptors translates to a clinical effect is still unknown. Bremelanotide was first described in the literature in 2003 when it...
Approved
Investigational
Matched Description: … [A179683] Since then it was investigated for its place in treating sexual dysfunction in men and women ... Other drugs used to treat female sexual dysfunction include [flibanserin], [estrogen], [ospemifene], and …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Amino Acids, Peptides, and Proteins ... Genito Urinary System and Sex Hormones …

Ramipril

Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. Ramiprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII)....
Approved
Matched Description: … It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. ... ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS ... Ramipril may be used in the treatment of hypertension, congestive heart failure, nephropathy, and to …
Matched Categories: … ACE Inhibitors and Diuretics ... ramipril and diuretics ... ramipril and felodipine ... ramipril and amlodipine ... ramipril and bisoprolol …

Dienogest

Dienogest is an orally-active semisynthetic progestogen which also possesses the properties of 17α-hydroxyprogesterone. It is a derivative of 19-nortestosterone and has antiandrogenic properties. It is primarily used as a contraceptive in combination with ethinylestradiol, or in other combination form pills approved in United States and Europe however it is not...
Approved
Matched Description: … Dienogest is commonly marketed as Visanne, Natazia and Qlaira. ... It is a derivative of 19-nortestosterone and has antiandrogenic properties. ... in combination with ethinylestradiol, or in other combination form pills approved in United States and …
Matched Mixtures name: … Estradiol Valerate and Estradiol Valerate/Dienogest ... Estradiol Valerate and Estradiol Valerate/Dienogest …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Hormone Antagonists ... dienogest and estrogen ... dienogest and estradiol ... dienogest and ethinylestradiol …

Testosterone propionate

Testosterone propionate is a slower-releasing anabolic steroid with a short half-life. It is a synthetic androstane steroid derivative of testosterone in the form of 17β propionate ester of testosterone. Testosterone propionate was developed initially by Watson labs, and FDA approved on February 5, 1974. Currently, this drug has been discontinued...
Approved
Investigational
Vet approved
Withdrawn
Matched Description: … [T83] Testosterone propionate was developed initially by Watson labs, and FDA approved on February 5, …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Testosterone and derivatives …

Fludrocortisone

Fludrocortisone is a synthetic mineralocorticoid used in conjunction with hydrocortisone to replace missing endogenous corticosteroids in patients with adrenal insufficiency.[A187169,A187187] It is functionally similar to aldosterone, the body's primary endogenous mineralocorticoid, and is structurally analogous to cortisol, differing only by a fluorine atom at the 9-position of the steroid structure...
Approved
Investigational
Matched Description: … A187187] It is functionally similar to [aldosterone], the body's primary endogenous mineralocorticoid, and …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Insulins ... fludrocortisone and antiinfectives ... fludrocortisone and antiinfectives ... fludrocortisone and antiinfectives …

Testosterone cypionate

Testosterone cypionate is a synthetic derivative of testosterone in the form of an oil-soluble 17 (beta)-cyclopentylpropionate ester. Its benefit compared to other testosterone derivatives is the slow rate of release after injection and longer half-life. It was developed by the company Pharmacia and Upjohn and FDA approved on July 25,...
Approved
Matched Description: … It was developed by the company Pharmacia and Upjohn and FDA approved on July 25, 1979. ... Its benefit compared to other testosterone derivatives is the slow rate of release after injection and …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Testosterone and derivatives …

Lindane

An organochlorine insecticide that has been used as a pediculicide and a scabicide. Lindane has been banned in California, United Kingdom, Australia, and many western countries due to concerns about neurotoxicity and adverse effects on the environment. In Canada, Lindane is not recommmended as a first-line therapy due to reports...
Approved
Withdrawn
Matched Description: … about neurotoxicity and adverse effects on the environment. ... An organochlorine insecticide that has been used as a pediculicide and a scabicide. ... Lindane has been banned in California, United Kingdom, Australia, and many western countries due to concerns …
Matched Categories: … Scabicides, Insecticides and Repellents ... Antiparasitic Products, Insecticides and Repellents …

Linzagolix

Linzagolix is a non-peptide, selective antagonist of the gonadotropin-releasing hormone (GnRH) receptor. It has been studied for the treatment of estrogen-dependent conditions such as uterine fibroids and endometriosis.[A253642,A253647] It is similar to other GnRH receptor antagonists like cetrorelix, relugolix, and elagolix. Uterine fibroids occur in >70% of women of reproductive...
Approved
Matched Description: … Linzagolix is a non-peptide, selective antagonist of the gonadotropin-releasing hormone (GnRH) receptor ... [A253662] As these fibroids are essentially estrogen-dependent phenomena, hormone therapies which suppress ... , and reproductive dysfunction. …
Matched Categories: … Gonadotropin Releasing Hormone Receptor Antagonists ... Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins …

Insulin glargine

Insulin glargine is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone ... and proteolysis. ... tissues such as the liver, fat cells, and skeletal muscle. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin glargine and lixisenatide …

Docetaxel

Docetaxel is a clinically well established anti-mitotic chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and non-small cell lung cancer. Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of paclitaxel.[A259676,L46466] Docetaxel reversibly binds to microtubulin with high affinity in a 1:1 stoichiometric...
Approved
Investigational
Matched Description: … Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of [paclitaxel]. ... chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and ... microtubulin with high affinity in a 1:1 stoichiometric ratio, allowing it to prevent cell division and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Oncotaxel Concentrate and solvent for solution for infusion 40 mg/ ml …

Hexylcaine

Hexylcaine hydrochloride is also known as cyclaine and osmocaine. It is a short acting local anesthetic that acts through inhibition of sodium channels. Patients experience an overdose may present with headache, tinnitus, numbness and tingling around the mouth and tongue, convulsions, inability to breathe, and decreased heart function. Hexylcaine has...
Approved
Withdrawn
Matched Description: … It is a short acting local anesthetic that acts through inhibition of sodium channels. ... mouth and tongue, convulsions, inability to breathe, and decreased heart function. ... Hexylcaine hydrochloride is also known as cyclaine and osmocaine. …

Econazole

A broad spectrum antimycotic with some action against Gram positive bacteria. It is used topically in dermatomycoses also orally and parenterally.
Approved
Matched Description: … It is used topically in dermatomycoses also orally and parenterally. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Hormone Antagonists ... Imidazole and Triazole Derivatives ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Displaying drugs 226 - 250 of 14523 in total