Displaying drugs 2601 - 2625 of 15294 in total
Mephenytoin
Mephenytoin is used for the treatment of refractory partial epilepsy. Mephenytoin is a solid. This compound belongs to the phenylhydantoins. These are heterocyclic aromatic compounds containing an imiazolidinedione moiety substituted by a phenyl group. Mephenytoin is known to target sodium channel protein type 5 subunit alpha. Cytochrome P450 2C19, Cytochrome...
Approved
Investigational
Withdrawn
Matched Description: … Mephenytoin and oxazolidinedione derivatives are associated with higher incidences of blood dyscrasias ... Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2B6, Cytochrome P450 1A2, and …
Besifloxacin
Besifloxacin is a fourth generation fluoroquinolone-type opthalmic antibiotic for the treatment of bacterial conjunctivitis. FDA approved on May 28, 2009.
Approved
Matched Iupac: … 7-[(3R)-3-aminoazepan-1-yl]-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Lovotibeglogene autotemcel
Lovotibeglogene autotemcel consists of autologous hematopoietic stem and progenitor cells transduced with the BB305 lentiviral vector encoding a modified β-globin gene. Specifically, lovotibeglogene autotemcel provides a functional copy of a modified beta-globin gene (βA-T87Q-globin) that when combined with α-globin, produces hemoglobins with similar oxygen-binding capacity as wild type hemoglobin. Additionally,...
Approved
Investigational
Matched Description: … Lovotibeglogene autotemcel consists of autologous hematopoietic stem and progenitor cells transduced ... FDA under the brand name Lyfgenia for the treatment of sickle cell disease (SCD) in patients ages 12 and ... treatments comprising the first cell-based gene therapies for the treatment of SCD in patients 12 years and …
Neisseria meningitidis serogroup B recombinant LP2086 A05 protein variant antigen
Neisseria meningitidis serogroup B recombinant lp2086 a05 protein variant antigen is a sterile vaccine for intramuscular injection indicated for the active immunization to prevent invasive disease caused by Neisseria meningitidis serogroup B. It is contained in the suspension of Trumenba, which is a vaccine is composed of two recombinant lipidated...
Approved
Matched Description: … one from subfamily B (A05 and B01, respectively). ... factor H binding protein (fHBP) variants from N. meningitidis serogroup B, one from fHBP subfamily A and …
Hydroxystilbamidine
Hydroxystilbamidine isethionate is used in the therapy of some patients with nonprogressive blastomycosis of the skin, and pulmonary or systemic blastomycosis in children, with fewer side effects than amphotericin B. Hydroxystilbamidine isethionate is also used in pathology for diagnostic purposes.
Approved
Matched Description: … isethionate is used in the therapy of some patients with nonprogressive blastomycosis of the skin, and …
Porfimer sodium
The purified component of hematoporphyrin derivative, it consists of a mixture of oligomeric porphyrins. It is used in photodynamic therapy (hematoporphyrin photoradiation); to treat malignant lesions with visible light and experimentally as an antiviral agent. It is the first drug to be approved in the use of photodynamic therapy in...
Approved
Investigational
Matched Description: … photodynamic therapy (hematoporphyrin photoradiation); to treat malignant lesions with visible light and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Imelasomeran
Imelasomeran was first approved in Canada on September 1, 2022, as one-half of Moderna's Spikevax Bivalent COVID-19 mRNA vaccine. It encodes for the viral spike protein of the Omicron BA.1 variant of SARS-CoV-2, a particularly infectious variant of concern first documented in 2021.
Approved
Investigational
Rivastigmine
Rivastigmine is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer's type. Rivastigmine is a cholinesterase inhibitor that inhibits both butyrylcholinesterase and acetylcholinesterase.
Approved
Investigational
Matched Description: … Rivastigmine is a cholinesterase inhibitor that inhibits both butyrylcholinesterase and acetylcholinesterase …
Bethanechol
Bethanechol is a synthetic ester that was initially synthesized in 1935.[A232905,L32539] As a cholinergic agent, bethanechol is similar in structure and pharmacological function to acetylcholine and is used in specific cases when stimulation of the parasympathetic nervous system is necessary.[A232905,L32539] For example, bethanechol is readily used to treat postoperative or...
Approved
Matched Description: … [A232905,L32539] As a cholinergic agent, bethanechol is similar in structure and pharmacological function ... to acetylcholine and is used in specific cases when stimulation of the parasympathetic nervous system …
Human papillomavirus type 33 L1 capsid protein antigen
Human papillomavirus type 33 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 33. The vaccine is prepared from the purified...
Approved
Matched Description: … It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused ... HPV Type 33 which are produced by separate fermentations in recombinant *Saccharomyces cerevisiae* and …
Dabigatran
Dabigatran is the active form of the orally bioavailable prodrug dabigatran etexilate.
Approved
Investigational
Matched Iupac: … carbamimidoylphenyl)amino]methyl}-1-methyl-1H-1,3-benzodiazol-5-yl)-N-(pyridin-2-yl)formamido]propanoic acid …
Decamethonium
Decamethonium is used in anesthesia to cause paralysis. It is a short acting depolarizing muscle relaxant. It is similar to acetylcholine and acts as a partial agonist of the nicotinic acetylcholine receptor.
Approved
Matched Description: … It is similar to acetylcholine and acts as a partial agonist of the nicotinic acetylcholine receptor. …
Aluminum chlorohydrex propylene glycol
Aluminum chlorohydrex propylene glycol is a complex consisting of Aluminum Chorohydrate and propylene glycol (PG). It is an antiperspirant active ingredient found in antiperspirant drug products for over-the-counter human use.
Approved
Matched Description: … Aluminum chlorohydrex propylene glycol is a complex consisting of Aluminum Chorohydrate and propylene …
Doravirine
Doravirine is an HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) intended to be administered in combination with other antiretroviral medicines.[L12729,L4562] Doravirine is available by itself or as a combination product of doravirine (100 mg), lamivudine (300 mg), and tenofovir disoproxil fumarate (300 mg). Doravirine is formally indicated for the treatment of...
Approved
Investigational
Matched Description: … adult patients with no prior antiretroviral treatment experience, further expanding the possibility and ... Doravirine is available by itself or as a combination product of doravirine (100 mg), lamivudine (300 mg), and …
Matched Categories: … lamivudine, tenofovir disoproxil and doravirine …
Matched Categories: … lamivudine, tenofovir disoproxil and doravirine …
Alosetron
Alosetron is a 5-HT3 antagonist used only for the management of severe diarrhoea-predominant irritable bowel syndrome (IBS) in women. Alosetron has an antagonist action on the 5-HT3 receptors and thus may modulate serotonin-sensitive gastrointestinal (GI) processes. Alosetron was voluntarily withdrawn from the US market in November 2000 by the manufacturer...
Approved
Withdrawn
Matched Description: … reports of severe adverse effects including ischemic colitis, severely obstructed or ruptured bowel, and ... Alosetron has an antagonist action on the 5-HT3 receptors and thus may modulate serotonin-sensitive gastrointestinal …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Categories: … Alimentary Tract and Metabolism …
Pemirolast
Pemirolast potassium is a slightly yellow powder that is soluble in water. It is a mast cell stabilizer that acts as an antiallergic agent. As an ophthalmic aqueous sterile solution, pemirolast is used for the prevention of itching of the eyes caused by allergies such as hay fever, and allergic...
Approved
Investigational
Matched Description: … pemirolast is used for the prevention of itching of the eyes caused by allergies such as hay fever, and …
Choline C-11
Choline C 11 Injection is a radioactive diagnostic agent for positron emission tomography (PET) imaging of pat ients with suspected prostate cancer recurrence and non-informative bone scintigraphy, computerized tomography (CT) or magnetic resonance imaging.
Approved
Matched Description: … for positron emission tomography (PET) imaging of pat ients with suspected prostate cancer recurrence and …
Copper Cu-64
Copper-64 is a radiopharmaceutical usually found in the +2 oxidation state as the complexes including the +1 state tend to be more unstable. It is used in molecular radiotherapy and positron emission tomography.
Approved
Matched Description: … [T604] It is used in molecular radiotherapy and positron emission tomography. …
Davesomeran
Davesomeran is a mRNA vaccine used in conjunction with elasomeran as part of the Moderna Bivalent COVID-19 vaccine. Similar to the previous Moderna COVID-19 vaccine, Moderna Bivalent vaccine encodes the full-length pre-fusion stabilized spike (S) protein to elicit an immune response.[L43882,L28026] However, with the addition of davesomeran, Moderna Bivalent vaccine...
Approved
Investigational
Matched Description: … Bivalent vaccine elicit a higher seroresponse both against the original SARS-CoV-2 strain and the BA ... [L43882] A phase 2 and 3 open-label study in participants 18 years or older who had previously received ... a two-dose primary series and one booster dose of Moderna COVID-19 Vaccine demonstrated that the Moderna …
N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine
N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine is a component of black rubber. It is also a dermatological sensitizer and allergen.
Sensitivity to N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine may be identified with a clinical patch test.
Approved
Matched Description: … It is also a dermatological sensitizer and allergen. …
Equine Botulinum Neurotoxin G Immune FAB2
Equine Botulinum Neurotoxin G Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype G. It is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes G in...
Approved
Experimental
Investigational
Matched Description: … symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes G in adults and …
Equine Botulinum Neurotoxin A Immune FAB2
Equine Botulinum Neurotoxin A Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype A. It is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes A in...
Approved
Experimental
Investigational
Matched Description: … symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes A in adults and …
Equine Botulinum Neurotoxin F Immune FAB2
Equine Botulinum Neurotoxin F Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype F. It is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes F in...
Approved
Experimental
Investigational
Matched Description: … symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes F in adults and …
Equine Botulinum Neurotoxin D Immune FAB2
Equine Botulinum Neurotoxin D Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype D. It is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes D in...
Approved
Experimental
Investigational
Matched Description: … symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes D in adults and …
Equine Botulinum Neurotoxin B Immune FAB2
Equine Botulinum Neurotoxin B Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype B. It is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes B in...
Approved
Experimental
Investigational
Matched Description: … symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes B in adults and …
Displaying drugs 2601 - 2625 of 15294 in total