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Displaying drugs 2601 - 2625 of 9554 in total

Roxadustat

Roxadustat is a first-in-class hypoxia-inducible factor prolyl hydroxylase inhibitor used to treat anemia associated with chronic kidney disease. It works by reducing the breakdown of the hypoxia-inducible factor (HIF), which is a transcription factor that stimulates red blood cell production in response to low oxygen levels. Roxadustat was first approved...
Approved
Investigational
Matched Description: … It works by reducing the breakdown of the hypoxia-inducible factor (HIF), which is a transcription factor …

Rosoxacin

Rosoxacin is a quinolone derivative antibiotic for the treatment of bacterial infection of respiratory tract, urinary tract, GI, CNS and immuno compromised patients. Rosoxacin is known to be effective against penicillin resistant strains and is a single dose orally administered drug, which avoids all complications of parenteral administration seen with...
Approved
Investigational
Matched Description: … Rosoxacin is a quinolone derivative antibiotic for the treatment of bacterial infection of respiratory ... penicillin resistant strains and is a single dose orally administered drug, which avoids all complications of …

Sodium phosphate, monobasic, unspecified form

Approved
Matched Mixtures name: … Reveos Select CPD/AS-5 Red Cell Preservative For Collection Of Blood …

Romosozumab

Romosozumab is a humanized monoclonal antibody indicated for the treatment of osteoperosis in postmenopausal women at high risk of fracture and patients who have failed in other treatments or are intolerant to other osteoperosis therapies . Romosozumab prevents bone resorption and induces the formation of bone though it is associated...
Approved
Investigational
Matched Description: … increased risk of cardiac death, heart attack, and stroke in one study[L5921,L5924]. ... women at high risk of fracture and patients who have failed in other treatments or are intolerant to ... Romosozumab is a humanized monoclonal antibody indicated for the treatment of osteoperosis in postmenopausal …
Matched Categories: … Drugs for Treatment of Bone Diseases …

Glofitamab

Glofitamab is a full-length bispecific monoclonal antibody with affinity for both CD20 and CD3 surface antigens found on B- and T-cells, respectively. It has a 2:1 configuration, with bivalency towards CD20 and monovalency towards CD3, and works by recruiting T-cells directly to the surface of cancerous B-cells.[L45698,A258488] Glofitamab was approved...
Approved
Investigational
Matched Description: … In June 2023, the FDA approved the use of glofitamab for the treatment of patients with relapsed or refractory ... systemic therapy under accelerated approval based on response rate and durability of response. ... [L45698,A258488] Glofitamab was approved by Health Canada in March 2023 for the treatment of certain …

Cephalosporium roseum

Cephalosporium roseum allergenic extract is used in allergenic testing.
Approved

Doconexent

A mixture of fish oil and primrose oil, doconexent is used as a high-docosahexaenoic acid (DHA) supplement. DHA is a 22 carbon chain with 6 cis double bonds with anti-inflammatory effects. It can be biosythesized from alpha-linolenic acid or commercially manufactured from microalgae. It is an omega-3 fatty acid and...
Approved
Investigational
Matched Description: … A mixture of fish oil and primrose oil, doconexent is used as a high-docosahexaenoic acid (DHA) supplement ... It is an omega-3 fatty acid and primary structural component of the human brain, cerebral cortex, skin …
Matched Mixtures name: … Herbs of Gold Salmon Oil 1000 mg …

Inula helenium root

Inula helenium root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental

Bleomycin

A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2 (B2 CAS # 9060-10-0). It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. Bleomycin A2 is used as the representative structure for Bleomycin.
Approved
Investigational
Matched Description: … A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin …

Turmeric

Turmeric is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Investigational

Eleuthero

Eleuthero is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental

Rofecoxib

Rofecoxib is used for the treatment of osteoarthritis, rheumatoid arthritis, acute pain in adults, and primary dysmenorrhea, as well as acute treatment of migraine attacks with or without auras. Rofecoxib is a solid. This compound belongs to the stilbenes. These are organic compounds containing a 1,2-diphenylethylene moiety. Stilbenes (C6-C2-C6 )...
Approved
Investigational
Withdrawn
Matched Description: … doses of 125, 25, and 50 mg is approximately 93%. ... The introduction of one or more hydroxyl groups to a phenyl ring lead to stilbenoids. ... primary dysmenorrhea, as well as acute treatment of migraine attacks with or without auras. …

Naphazoline

Naphazoline is a rapid acting imidazoline sympathomimetic vasoconstrictor of ocular or nasal artierioles[L5804,L5807]. It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations[L5804,L5807]. Naphazoline was first developed in 1942 as a nasal formulation for congestion .
Approved
Investigational
Matched Description: … Naphazoline is a rapid acting imidazoline sympathomimetic vasoconstrictor of ocular or nasal artierioles …
Matched Mixtures name: … FENIXIL-OF …

Rosiglitazone

Rosiglitazone is an anti-diabetic drug in the thiazolidinedione class of drugs. It is marketed by the pharmaceutical company GlaxoSmithKline as a stand-alone drug (Avandia) and in combination with metformin (Avandamet) or with glimepiride (Avandaryl). Like other thiazolidinediones, the mechanism of action of rosiglitazone is by activation of the intracellular receptor...
Approved
Investigational
Matched Description: … Like other thiazolidinediones, the mechanism of action of rosiglitazone is by activation of the intracellular ... Recent research has suggested that rosiglitazone may also be of benefit to a subset of patients with ... This is the subject of a clinical trial currently underway. …

Sulfoxone

Sulfoxone is a water-soluble sulfone used as an antileprosy drug. It has been used with limited success in the treatment of dermatitis herpetiformis.
Approved
Matched Description: … It has been used with limited success in the treatment of dermatitis herpetiformis. …
Matched Categories: … Drugs for Treatment of Lepra …

Clostridium tetani toxoid antigen (formaldehyde inactivated)

Clostridium tetani toxoid antigen (formaldehyde inactivated) is a vaccine for intramuscular injection. It is used for active immunization of children 7 years of age or older, and adults, for prevention of tetanus. The toxoid in the Clostridium tetani culture is grown and detoxified followed by purification via ammonium sulfate filtration...
Approved
Matched Description: … It is used for active immunization of children 7 years of age or older, and adults, for prevention of …
Matched Mixtures name: … FINAL BULK OF ADSORBED TD VACCINE …

Valproate bismuth

Valproate bismuth is available in Canada in the over-the-counter medication Neo-Laryngobis.
Approved
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Iofetamine I-123

Approved
Matched Categories: … Diagnostic Uses of Chemicals ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Terizidone

Terizidone has been used in trials studying the treatment of Tuberculosis, HIV Infections, Multidrug Resistant Tuberculosis, and Extensively-drug Resistant Tuberculosis.
Approved
Investigational
Matched Description: … Terizidone has been used in trials studying the treatment of Tuberculosis, HIV Infections, Multidrug …
Matched Categories: … Drugs for Treatment of Tuberculosis …

Trolamine

Trolamine, which is also referred to as triethanolamine (TEA), is a tertiary amine and a triol. It is a bifunctional compound that exhibits both properties of alcohols and amines. Trolamine contains small amounts of diethanolamine and ethanolamine and may also act as an antioxidant against the auto-oxidation of animal and...
Approved
Matched Description: … against the auto-oxidation of animal and vegetable fats [A27174]. ... It is a bifunctional compound that exhibits both properties of alcohols and amines. ... Trolamine contains small amounts of diethanolamine and ethanolamine and may also act as an antioxidant …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers …

Sporotrichum pruinosum

Sporotrichum pruinosum is a fungus which can provoke allergic reactions. Sporotrichum pruinosum extract is used in allergenic testing.
Approved

Rolitetracycline

A pyrrolidinylmethyl tetracycline.
Approved
Matched Categories: … combinations of tetracyclines …

Procaine

A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016). Procaine has also been investigated as an oral entry inhibitor in...
Approved
Investigational
Vet approved
Matched Description: … A local anesthetic of the ester type that has a slow onset and a short duration of action. …
Matched Categories: … Esters of Aminobenzoic Acid ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Pheneticillin

Pheneticillin (or phenethicillin) is a penicillin antibiotic which is approved for use internationally.
Approved
Matched Categories: … combinations of penicillins …

Omidenepag isopropyl

Omidenepag isopropyl is a topical ocular hypotensive agent used to reduce intraocular pressure (IOP) in patients with glaucoma and ocular hypertension. Omidenepag isopropyl is quickly metabolized to its active metabolite, omidenepag, a molecule with high selectivity and agonistic activity towards the prostaglandin E2 (EP2) receptor.[A253263,A253268] Prostanoid FP receptor agonists (FP...
Approved
Investigational
Matched Description: … [A253268] In September 2022, the FDA approved the use of omidenepag isopropyl.[L43503] ... The use of an EP2 receptor agonist such as omidenepag represents an alternative in these scenarios. ... [A253263,A253268] Prostanoid FP receptor agonists (FP agonists), such as [latanoprost], are part of the …
Matched Categories: … combinations of sulfonamides …
Displaying drugs 2601 - 2625 of 9554 in total