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Displaying drugs 251 - 275 of 12244 in total

Nabumetone

Nabumetone was originally developed as a non-acidic non-steroidal anti-inflammatory drug (NSAID).[label] It was thought to avoid trapping of the drug in the stomach by making it unable to dissociate into ions which was believed to reduce GI toxicity by limiting local action. While slightly reduced, possibly due to a degree...
Approved
Matched Products: … DOLORSIN 1 G …

Potassium chloride

A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives. The FDA withdrew its approval for the use of all solid oral dosage form drug products containing potassium chloride that supply 100 mg or more of...
Approved
Withdrawn
Matched Mixtures name: … Isolyte R In 5% Dextrose ... Normosol-R & 5% Dextrose ... Plasma-Lyte R …
Matched Products: … APO-K TABLET 600MG (S/R) ... POTASSIUM CHLORIDE MIXTURE 500 mg/5 ml ... POTASYUM KLORUR 75 MG /1 ML ENJEKSİYONLUK ÇÖZELTİ, 10 AMPUL …

Palivizumab

Humanized monoclonal antibody (IgG1k) produced by recombinant DNA technology, directed to an epitope in the A antigenic site of the F protein of respiratory syncytial virus (RSV). Synagis is a composite of human (95%) and murine (5%) antibody sequences. The human heavy chain sequence was derived from the constant domains...
Approved
Investigational
Matched Description: … Synagis is a composite of human (95%) and murine (5%) antibody sequences. ... 2% carbohydrate by weight and has a molecular weight of 147.7 kDa +/- 1 kDa (MALDI-TOF) ... derived from the constant domains of human IgG1 and the variable framework regions of the VH genes Cor (1) …
Matched Products: … SYNAGIS 100 MG/1 ML IM ENJEKSIYONLUK ÇÖZELTI IÇEREN FLAKON,1 ADET ... SYNAGIS 100 MG/1 ML IM ENJEKSIYONLUK ÇÖZELTI IÇEREN FLAKON, 1 ADET ... SYNAGIS 100 ML IM ENJEKSIYONLUK ÇÖZELTI IÇEREN FLAKON,1 ADET …

Rupatadine

Rupatadine is a dual histamine H1 receptor and platelet activating factor receptor antagonist that is used for symptomatic relief in seasonal and perennial rhinitis as well as chronic spontaneous urticaria. It was approved for marketing in Canada under the tradename Rupall and comes in tablet formulation for adult use and...
Approved
Matched Iupac: … 13-chloro-2-{1-[(5-methylpyridin-3-yl)methyl]piperidin-4-ylidene}-4-azatricyclo[9.4.0.0^{3,8}]pentadeca ... -1(15),3(8),4,6,11,13-hexaene …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … RUPAFİN 1 MG / ML ORAL ÇÖZELTİ, 120 ML ... Rupafin 1 mg/ml Lösung zum Einnehmen ... ANTHİX 1 MG/ML PEDİATRİK ORAL ÇÖZELTİ, 120 ML …

Ixekizumab

Ixekizumab is a humanized immunoglobulin G subclass 4 (IgG4) monoclonal antibody (mAb) against interleukin-17A (IL-17A) and prevents it from interacting with the IL-17A receptor. As IL-17A is a pro-inflammatory cytokine involved in inflammation and immune responses, blocking its effect is beneficial for use in inflammatory conditions. In particular, IL-17A has...
Approved
Investigational
Matched Products: … COPELLOR 80 MG/1 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 1 ADET ... COPELLOR 80 MG/1 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET ... COPELLOR 80 MG/1 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 2 ADET …

Nonacog beta pegol

Nonacog beta pegol is a recombinant coagulation factor IX derivative. It is produced without animal-derived materials and with an attached 40kDa polyethylene glycol (PEG) molecule for peptide activation by a site-directed glycoPEGylation. Once activated, the activation molecule with PEG is cleaved to leave the activated factor IX (Factor IXa). Nonacog...
Approved
Investigational
Matched Products: … REFİXİA 500 IU ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİNTOZ VE ÇÖZÜCÜ , 1 ADET FLAKON + 1 ADET ÇÖZÜCÜ İÇEREN ... REFİXİA 1000 IU ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİNTOZ VE ÇÖZÜCÜ , 1 ADET FLAKON + 1 ADET ÇÖZÜCÜ İÇEREN ... REFİXİA 2000 IU ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİNTOZ VE ÇÖZÜCÜ , 1 ADET FLAKON + 1 ADET ÇÖZÜCÜ İÇEREN …

Leuprolide

Leuprolide is a synthetic 9-residue peptide analogue of gonadotropin-releasing hormone (GnRH). Unlike the endogenous decapeptide GnRH, leuprolide contains a single D-amino acid (D-leucyl) residue, which helps to increase its circulating half-life from three to four minutes to approximately three hours. As a GnRH mimic, leuprolide is capable of binding to...
Approved
Investigational
Matched Iupac: … (2S)-1-[(2S)-5-carbamimidamido-2-[(2S)-2-[(2R)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol ... -4-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-(1H-indol-3-yl)propanamido]propanamido] …
Matched Salts cas: … 944347-41-5 …
Matched Products: … LEUPRONE 5 MG IMPLANT, 1 ADET ... PROSALID 5 MG/ML SUBKUTAN ENJEKSİYON İÇİN ÇÖZELTİ İÇEREN FLAKON, 1 FLAKON ... LUCRIN INJECTION 5 mg/ml …

Glucagon

Glucagon is a 29 amino acid hormone used as a diagnostic aid in radiologic exams to temporarily inhibit the movement of the gastrointestinal tract and to treat severe hypoglycemia.[L7634,L7637,L7640,L7643,L8519] Glucagon raises blood sugar through activation of hepatic glucagon receptors, stimulating glycogenolysis and the release of glucose.[L7640,L7643] Glucagon was granted FDA...
Approved
Matched Products: … R-GLUCAGON LILLY ... GLUCAGEN HYPOKIT 1 MG ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET ... Gvoke HypoPen 1 mg Auto-Injector …

Ceftazidime

Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis,...
Approved
Matched Iupac: … -8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}pyridin-1-ium ... 1-{[(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetamido]-2-carboxylato …
Matched Mixtures name: … CEFAZIME FOR INJECTION 1 g/vial …
Matched Products: … IESETUM 1 G IV/IM ENJEKTABL FLAKON, 1 ADET ... SEFAVİS 1 G IM/IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 FLAKON VE 1 AMPUL ... FORTUM INYECTABLE 1 G …

Nabilone

Nabilone (marketed as Cesamet) is a synthetic form of delta-9-tetrahydrocannabinol (Δ⁹-THC), the primary psychoactive component of cannabis (marijuana). Although structurally distinct from THC, nabilone mimics THC's structure and pharmacological activity through weak partial agonist activity at Cannabinoid-1 (CB1R) and Cannabinoid-2 (CB2R) receptors, however it is considered to be twice as...
Approved
Investigational
Matched Iupac: … (6aR,10aR)-1-hydroxy-6,6-dimethyl-3-(2-methyloctan-2-yl)-6H,6aH,7H,8H,9H,10H,10aH-benzo[c]isochromen- …
Matched Description: … Nabilone is a racemate consisting of the (S,S) and the (R,R) isomers. ... mimics THC's structure and pharmacological activity through weak partial agonist activity at Cannabinoid-1 …
Matched Products: … Canemes 1 mg Kapseln …

Emicizumab

Emicizumab is a humanized recombinant monoclonal antibody that mimics the function of the coagulation Factor VIII and it has the capacity to bind simultaneously to activated Factor IX and Factor X. The ability of Emicizumab to bind to all these three different factors allows it to overcome immunogenicity and unstable...
Approved
Investigational
Matched Products: … HEMLİBRA 150 MG/ 1 ML S.C. ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... HEMLİBRA 30 MG/ 1 ML S.C. ENJEKSİYONLUK ÇÖZELTİ , 1 ADET ... ENJEKSİYONLUK ÇÖZELTİ, 1 ADET …

Milrinone

Heart failure is a multifactorial condition that affects roughly 1-2% of the adult population. Often the result of long-term myocardial ischemia, cardiomyopathy, or other cardiac insults, heart failure results from an inability of the heart to perfuse peripheral tissues with sufficient oxygen and metabolites, resulting in complex systemic pathologies. Heart...
Approved
Matched Synonyms: … 1,6-Dihydro-2-methyl-6-oxo(3,4'-bipyridine)-5-carbonitrile …
Matched Iupac: … 2-methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carbonitrile …
Matched Description: … Heart failure is a multifactorial condition that affects roughly 1-2% of the adult population. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Milrinon Hikma 1 mg/ml Injektionslösung ... Milrinon Tillomed 1 mg/ml Injektions-/Infusionslösung ... Milrinon Carino 1 mg/ml Injektions- oder Infusionslösung …

Human immunoglobulin G

Intravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human plasma via Cohn fractionation. The purification process includes cold alcohol fractionation, polyethylene glycol precipitation, and ion exchange chromatography. IVIg contains the same distribution of IgG antibody subclasses as is found in the general human population....
Approved
Investigational
Matched Products: … FLEBOGAMMA % 5 5 GR 100 ML FLAKON, 1 ADET ... FLEBOGAMMA % 5 DIF 5 G/100 ML INFUZYON ICIN COZELTI ICEREN 1 FLAKON ... FLEBOGAMMA %5 2.5 GR 50 ML FLAKON, 1 ADET …

Glimepiride

First introduced in 1995, glimepiride is a member of the second-generation sulfonylurea (SU) drug class used for the management of type 2 diabetes mellitus (T2DM) to improve glycemic control. Type 2 diabetes is a metabolic disorder with increasing prevalences worldwide; it is characterized by insulin resistance in accordance with progressive...
Approved
Matched Iupac: … -(2-{4-[({[(1r,4r)-4-methylcyclohexyl]carbamoyl}amino)sulfonyl]phenyl}ethyl)-2,5-dihydro-1H-pyrrole-1- …
Matched Mixtures name: … GLUCOVEL 1 ... VELACOM PLUS 1/250 ... AMARYL®M 1 MG/ 500 MG …
Matched Products: … GLIMEPIRIDE SANDOZ(R) (2 MG) ... DIAPRIDE-1 TABLET 1 mg ... GLUVAS 1 …

Hepatitis B Vaccine (Recombinant)

Hepatitis B Vaccine is an ingredient in the EMA-withdrawn product Quintanrix. It is marketed in Canada as Engerix B. It is also a part of Twinrix (Hep A/Hep B vaccine) available also in Canada. The hepatitis B virus induces a severe form of viral hepatitis. Other causative agents are hepatitis...
Approved
Withdrawn
Matched Description: … Europe, 4% to 6% of the population are infected during their lifetime (mostly young adults); between 5% …
Matched Salts cas: … 351186-51-1 …
Matched Mixtures name: … HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 1 ADET ... TWINRIX ERİŞKİN IM 1 ML SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR ... HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET …
Matched Products: … HBVAXPRO PEDİYATRİK/ADOLESAN 5 MCG/0.5 ML IM ENJEKSİYON İÇİN SUSPANSİYON İÇEREN FLAKON, 1 ADET ... HBVAXPRO INJECTION 5 mcg/0.5 ml ... EUVAX-B 1 ML FLAKON, 1 ADET …

Talbutal

Talbutal, also called 5-allyl-5-sec-butylbarbituric acid, is a barbiturate with a short to intermediate duration of action. Talbutal is a schedule III drug in the U.S.
Approved
Illicit
Matched Synonyms: … 5-allyl-5-sec-butylbarbituric acid ... (RS)-5-allyl-5-sec-butylpyrimidine-2,4,6(1H,3H,5H)-trione …
Matched Iupac: … 5-(butan-2-yl)-5-(prop-2-en-1-yl)-1,3-diazinane-2,4,6-trione …
Matched Description: … Talbutal, also called 5-allyl-5-sec-butylbarbituric acid, is a barbiturate with a short to intermediate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Turoctocog alfa pegol

Turoctocog alfa pegol is a pegylated version of turoctocog alfa. Novo Nordisk's brand name Esperoct (turoctocog alfa pegol, N8-GP) was approved by the US FDA on February 19, 2019. Fundamentally, the N8-GP moiety is identical to turoctocog alfa, a recombinant human clotting factor VIII (rFVIII) with a truncated B-domain made...
Approved
Matched Description: … Nordisk's brand name Esperoct (turoctocog alfa pegol, N8-GP) was approved by the US FDA on February 19, 2019 …
Matched Products: … ESPEROCT 500 IU ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET ... ESPEROCT 1000 IU ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET ... ESPEROCT 1500 IU ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET …

Dimethicone

Dimethicone is a silicone oil that is also known as polydimethylsiloxane (PDMS). It has viscoelastic properties. Dimethicone is used as a surfactant, antifoaming agent, carminative in various products such as medical devices, food products, and lubricants. It is used in a number of health and beauty products including hair care...
Approved
Matched Mixtures name: … IDENEL Light R Tox Daily …
Matched Products: … Babies R Us Gas Relief Infants ... Siero Vanish Oi L Powde R Pact ... 4-N-1 Wash …

Phenylephrine

Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil, and induce local vasoconstriction. The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s. Phenylephrine was granted FDA approval in 1939.
Approved
Matched Synonyms: … R(-)-Phenylephrine …
Matched Iupac: … 3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol …
Matched Description: … Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate …
Matched Salts cas: … 1416-03-1 …
Matched Mixtures name: … PİRETİKOL PLUS 160 MG/5 ML+1 MG/5 ML+2.5 MG/5 ML PEDİATRİK ŞURUP, 100 ML ... Dibucaine HCl 0.5% / Lidocaine 15% / Phenylephrine HCl 1% / Prilocaine 5% ... R-Tanna …
Matched Categories: … Adrenergic alpha-1 Receptor Agonists …
Matched Products: … FENOSED % 10 STERIL GÖZ DAMLASI, 5 ML ... FENOSED % 2.5 STERIL GÖZ DAMLASI, 5 ML ... FENİLEFRİN % 10 STERİL GÖZ DAMLASI, ÇÖZELTİ, 5 ML …

Amylmetacresol

Amylmetacresol is an antiseptic available in Canada over-the-counter in a number of lozenges for the treatment of sore throat and minor mouth infections , . Amylmetacresol is often combined with dichlorobenzyl alcohol and menthol in the commonly used sore throat lozenges, known as Strepsils . The acute sore throat (pharyngitis)...
Approved
Matched Synonyms: … 5-methyl-2-pentylphenol …
Matched Iupac: … 5-methyl-2-pentylphenol …
Matched Mixtures name: … ซีพาคอล(R) อาร์เอ็กซ์ ... ซีพาคอล(R) อาร์เอ็กซ์ …
Matched Products: … Strepsils 1 - Loz …

Treprostinil

Treprostinil is a stable tricyclic analogue of prostacyclin that promotes the vasodilation of pulmonary and systemic arterial vascular beds and the inhibition of platelet aggregation.[L41855,L41860,L41865] It reduces symptoms in patients with pulmonary arterial hypertension (PAH) and pulmonary hypertension associated with interstitial lung disease.[L41855,L41860] The first agent approved for the treatment...
Approved
Investigational
Matched Iupac: … 5-yl]oxy}acetic acid ... 2-{[(1R,2R,3aS,9aS)-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-1H,2H,3H,3aH,4H,9H,9aH-cyclopenta[b]naphthalen- …
Matched Description: … The first generic form of treprostinil became available in 2019.[A248775] ... However, the use of epoprostenol is limited due to its short half-life (3-5 min) and instability at room …
Matched Products: … REMODULIN 5 mg/ml Infusionslösung ... Treposa 5 mg/ml Infusionslösung ... Trisuva 5 mg/ml Infusionslösung …

Flunitrazepam

Flunitrazepam is a benzodiazepine with pharmacologic actions similar to those of diazepam that can cause anterograde amnesia. Some reports indicate that it is used as a date rape drug and suggest that it may precipitate violent behavior. The United States Government has banned the importation of this drug.
Approved
Illicit
Matched Iupac: … 5-(2-fluorophenyl)-1-methyl-7-nitro-2,3-dihydro-1H-1,4-benzodiazepin-2-one …
Matched Products: … ROHYPNOL 1 ... Rohypnol 1 mg - Filmtabletten ... ROHYPNOL ROCHE TABLETAS 1 MG …

Cianidanol

An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin (cis) forms.
Approved
Withdrawn
Matched Iupac: … (2R,3S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Fluconazole

Fluconazole, commonly known as Diflucan, is an antifungal drug used for the treatment of both systemic and superficial fungal infections in a variety of tissues. It was initially approved by the FDA in 1990. This drug is an azole antifungal, in the same drug family as ketoconazole and itraconazole. Fluconazole...
Approved
Investigational
Matched Iupac: … 2-(2,4-difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol …
Matched Mixtures name: … Ciclopirox 8% / Fluconazole 1% / Terbinafine HCl 1% ... Canesoral Combi 1 Day ... Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4% …
Matched Products: … FLUCONAZOL50 MG/ 5 ML ... LUKO 25 MG/5 ML ŞURUP, 70 ML ... TRIFLUCAN 5 MG/ML SURUP, 150 ML …

Remdesivir

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19), which is a respiratory disease that is capable of progressing to viral pneumonia and acute respiratory distress syndrome (ARDS); COVID-19 can be fatal. Like other RNA viruses, SARS-CoV-2 depends on an RNA-dependent RNA polymerase...
Approved
Investigational
Matched Iupac: … 2-ethylbutyl (2S)-2-{[(S)-{[(2R,3S,4R,5R)-5-{4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl}-5-cyano-3,4-dihydroxyoxolan …
Matched Description: … acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 …
Matched Categories: … MATE 1 Inhibitors …
Matched Products: … VEKLURY 100 MG İNFÜZYONLUK ÇÖZELTİ KONSANTRESİ İÇİN TOZ, 1 ADET …
Displaying drugs 251 - 275 of 12244 in total