Displaying drugs 251 - 275 of 11279 in total
Tolevamer
Sodium polystyrene sulfonate is a medication used to treat abnormally high potassium levels. It may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines. It is also an effective topical microbicide and spermicide, inhibiting the genital transfection of, among others, HIV.
Approved
Investigational
Matched Synonyms: … poly(styrene-4-sulfonic acid) …
Matched Salts cas: … 37286-92-3 …
Matched Salts cas: … 37286-92-3 …
Abacavir
Abacavir (ABC) is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS. Chemically, it is a synthetic carbocyclic nucleoside and is the enantiomer with 1S, 4R absolute configuration on the cyclopentene ring. In vivo, abacavir sulfate dissociates to its free base, abacavir.
Approved
Investigational
Matched Synonyms: … {(1S-cis)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol …
Matched Iupac: … [(1S,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl]methanol …
Matched Iupac: … [(1S,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl]methanol …
Ivermectin
Ivermectin is a semi-synthetic antiparasitic medication derived from avermectins, a class of highly-active broad-spectrum antiparasitic agents isolated from the fermentation products of Streptomyces avermitilis. Ivermectin itself is a mixture of two avermectins, comprising roughly 90% 5-O-demethyl-22,23-dihydroavermectin A1a (22,23-dihydroavermectin B1a) and 10% 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)avermectin A1a (22,23-dihydroavermectin B1b). Ivermectin is mainly used in...
Approved
Investigational
Vet approved
Matched Iupac: … -6-methyloxan-2-yl]oxy}-4-methoxy-6-methyloxan-2-yl]oxy}-5,11',13',22'-tetramethyl-3',7',19'-trioxaspiro ... ',22'-tetramethyl-6-(propan-2-yl)-3',7',19'-trioxaspiro[oxane-2,6'-tetracyclo[15.6.1.1^{4,8}.0^{20,24 ... 5-{[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-4-methoxy-6-methyloxan-2-yl]oxy}-5,11',13 ... (1'R,2R,4'S,5S,6R,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'R,24'S)-21',24'-dihydroxy-12'-{[(2R,4S,5S,6S)- ... }]pentacosane]-10',14',16',22'-tetraen-2'-one; (1'R,2R,4'S,5S,6R,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21 …
Matched Mixtures name: … Ivermectin 1% / Metronidazole 1% / Niacinamide 4% ... 171083 Ivermectin 1% / Metronidazole 1% / Niacinamide 4% ... Brimonidine Tartrate 0.25% / Ivermectin 1% / Metronidazole 1% / Niacinamide 4% …
Matched Products: … ZİVER 3 MG TABLET, 4 ADET ... ARMEC 3 MG TABLET, 4 ADET ... Scabioral 3 mg Tabletten …
Matched Mixtures name: … Ivermectin 1% / Metronidazole 1% / Niacinamide 4% ... 171083 Ivermectin 1% / Metronidazole 1% / Niacinamide 4% ... Brimonidine Tartrate 0.25% / Ivermectin 1% / Metronidazole 1% / Niacinamide 4% …
Matched Products: … ZİVER 3 MG TABLET, 4 ADET ... ARMEC 3 MG TABLET, 4 ADET ... Scabioral 3 mg Tabletten …
Sulfacetamide
An anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.
Approved
Matched Synonyms: … N-Acetyl-4-aminobenzenesulfonamide ... N(1)-Acetyl-4-aminophenylsulfonamide …
Matched Iupac: … N-(4-aminobenzenesulfonyl)acetamide …
Matched Mixtures name: … SulfaCleanse 8/4 ... Sulfatol 10-4 Cleansing pads ... Sodium Sulfacetamide 9% - Sulfur 4% …
Matched Iupac: … N-(4-aminobenzenesulfonyl)acetamide …
Matched Mixtures name: … SulfaCleanse 8/4 ... Sulfatol 10-4 Cleansing pads ... Sodium Sulfacetamide 9% - Sulfur 4% …
Oxiconazole
Oxiconazole is an antifungal agent that is commonly found in topical formulations. It is marketed under the brand names Oxistat and Oxistat, and is used in the treatment of various skin infections such as athlete's foot, jock itch and ringworm.
Approved
Matched Synonyms: … 2',4'-Dichloro-2-imidazol-1-ylacetophenone (Z)-[O-(2,4-dichlorobenzyl)oxime] …
Lornoxicam
Lornoxicam (chlortenoxicam) is a new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory and antipyretic properties. Lornoxicam differs from other oxicam compounds in its potent inhibition of prostaglandin biosynthesis, a property that explains the particularly pronounced efficacy of the drug. Lornoxicam is approved for use in Japan.
Approved
Investigational
Matched Iupac: … 6-chloro-4-hydroxy-2-methyl-1,1-dioxo-N-(pyridin-2-yl)-2H-1λ⁶-thieno[2,3-e][1,2]thiazine-3-carboxamide …
Matched Products: … flakon+3 çözücü ampul ... Xefo 4 mg - Filmtabletten ... MG IM/IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ VE ÇÖZÜCÜ, 1 flakon+1 çözücü ampul ve 3 …
Matched Products: … flakon+3 çözücü ampul ... Xefo 4 mg - Filmtabletten ... MG IM/IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ VE ÇÖZÜCÜ, 1 flakon+1 çözücü ampul ve 3 …
Arbutin
Extracted from the dried leaves of bearberry plant in the genus Arctostaphylos and other plants commonly in the Ericaceae family, arbutin is a beta-D-glucopyranoside of DB09526. It is found in foods, over-the-counter drugs, and herbal dietary supplements . Most commonly, it is an active ingredient in skincare and cosmetic products...
Approved
Matched Synonyms: … 4-Hydroxyphenyl-beta-D-glucopyranoside …
Matched Iupac: … (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol …
Matched Iupac: … (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol …
Probucol
A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
Approved
Investigational
Matched Synonyms: … Acetone bis(3,5-di-tert-butyl-4-hydroxyphenyl) mercaptole …
Matched Iupac: … 2,6-di-tert-butyl-4-({2-[(3,5-di-tert-butyl-4-hydroxyphenyl)sulfanyl]propan-2-yl}sulfanyl)phenol …
Matched Iupac: … 2,6-di-tert-butyl-4-({2-[(3,5-di-tert-butyl-4-hydroxyphenyl)sulfanyl]propan-2-yl}sulfanyl)phenol …
Mitotane
Mitotane is an adrenolytic isomer of the insecticide dichlorodiphenyldichloroethane (DDD) - itself a metabolite of dichlorodiphenyltrichloroethane (DDT) - that inhibits cells of the adrenal cortex and their production of hormones. It has been in use since 1959 for the treatment of inoperable adrenocortical carcinoma and is used off-label for the...
Approved
Matched Synonyms: … 1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]-benzene …
Matched Iupac: … 1-chloro-4-[2,2-dichloro-1-(2-chlorophenyl)ethyl]benzene …
Matched Iupac: … 1-chloro-4-[2,2-dichloro-1-(2-chlorophenyl)ethyl]benzene …
Dronabinol
Dronabinol (marketed as Marinol) is a synthetic form of delta-9-tetrahydrocannabinol (Δ⁹-THC), the primary psychoactive component of cannabis (marijuana). THC demonstrates its effects through weak partial agonist activity at Cannabinoid-1 (CB1R) and Cannabinoid-2 (CB2R) receptors, which results in the well-known effects of smoking cannabis such as increased appetite, reduced pain, and...
Approved
Illicit
Matched Synonyms: … 3-Pentyl-6,6,9-trimethyl-6a,7,8,10a-tetrahydro-6H-dibenzo(b,d)pyran-1-ol ... 6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol …
Matched Iupac: … (6aR,10aR)-6,6,9-trimethyl-3-pentyl-6H,6aH,7H,8H,10aH-benzo[c]isochromen-1-ol …
Matched Iupac: … (6aR,10aR)-6,6,9-trimethyl-3-pentyl-6H,6aH,7H,8H,10aH-benzo[c]isochromen-1-ol …
Ethyl hydroxybenzoate
Approved
Experimental
Matched Synonyms: … 4-hydroxybenzoic acid ethyl ester …
Matched Iupac: … ethyl 4-hydroxybenzoate …
Matched Iupac: … ethyl 4-hydroxybenzoate …
Ropinirole
Ropinirole, also known as ReQuip, is a non-ergoline dopamine agonist used in Parkinson's disease and restless legs syndrome [FDA label], . It is manufactured by GlaxoSmithKline Pharmaceuticals. Ropinirole was initially approved in 1997 by the FDA [FDA label] for the management of Parkinson's disease. In 2005, it was the first...
Approved
Investigational
Matched Iupac: … 4-[2-(dipropylamino)ethyl]-2,3-dihydro-1H-indol-2-one …
Matched Products: … ROPINIROL AL 3 MG RET ... ROPINIROL-NEURAX 3 MG ... ROPINIROL-NEURAX 3 RET …
Matched Products: … ROPINIROL AL 3 MG RET ... ROPINIROL-NEURAX 3 MG ... ROPINIROL-NEURAX 3 RET …
Clofibrate
A fibric acid derivative used in the treatment of hyperlipoproteinemia type III and severe hypertriglyceridemia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p986)
Approved
Investigational
Matched Synonyms: … 2-(4-Chlorophenoxy)-2-methylpropanoic acid ethyl ester …
Matched Iupac: … ethyl 2-(4-chlorophenoxy)-2-methylpropanoate …
Matched Iupac: … ethyl 2-(4-chlorophenoxy)-2-methylpropanoate …
Lymecycline
Lymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and other susceptible bacterial infections.[L13880,L13883] It has been proven a cost-effective alternative to treatment with minocycline with comparable safety and efficacy. Lymecycline was initially discovered in 1961. It is marketed by Galderma and used in the UK...
Approved
Investigational
Matched Synonyms: … N6-((4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo- ... (+)-N-(5-Amino-5-carboxypentylaminomethyl)-4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy …
Matched Iupac: … (2S)-6-[({[(4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a …
Matched Iupac: … (2S)-6-[({[(4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a …
Cefuroxime
Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Approved
Matched Synonyms: … (6R,7R)-3-[(carbamoyloxy)methyl]-7-{[(2Z)-2-furan-2-yl-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo …
Matched Iupac: … (6R,7R)-3-[(carbamoyloxy)methyl]-7-[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo …
Matched Products: … CEFROX 750 MG IM ENJEKSIYON IÇIN TOZ IÇEREN FLAKON, 3 FLAKON + 3 ÇÖZÜCÜ AMPUL …
Matched Iupac: … (6R,7R)-3-[(carbamoyloxy)methyl]-7-[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo …
Matched Products: … CEFROX 750 MG IM ENJEKSIYON IÇIN TOZ IÇEREN FLAKON, 3 FLAKON + 3 ÇÖZÜCÜ AMPUL …
Ramipril
Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. Ramiprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII)....
Approved
Matched Synonyms: … (2S-(1(R*(R*)),2alpha,3abeta,6abeta))-1-(2-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta …
Matched Iupac: … (2S,3aS,6aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-octahydrocyclopenta[ …
Matched Iupac: … (2S,3aS,6aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-octahydrocyclopenta[ …
Brexpiprazole
Brexpiprazole is an atypical antipsychotic and a novel D2 dopamine and serotonin 1A partial agonist called serotonin-dopamine activity modulator (SDAM). It has a high affinity for serotonin, dopamine and alpha (α)-adrenergic receptors. Although it is structurally similar to aripiprazole, brexpiprazole has different binding affinities for dopamine and serotonin receptors. Compared...
Approved
Investigational
Matched Iupac: … 7-{4-[4-(1-benzothiophen-4-yl)piperazin-1-yl]butoxy}-1,2-dihydroquinolin-2-one …
Matched Description: … It has a high affinity for serotonin, dopamine and alpha (α)-adrenergic receptors. …
Matched Products: … REXULTI (BREXPIPRAZOLE) TABLETS 3 MG ... REXULTI (BREXPIPRAZOLE) TABLETS 4 MG …
Matched Description: … It has a high affinity for serotonin, dopamine and alpha (α)-adrenergic receptors. …
Matched Products: … REXULTI (BREXPIPRAZOLE) TABLETS 3 MG ... REXULTI (BREXPIPRAZOLE) TABLETS 4 MG …
Levoleucovorin
Levoleucovorin is the enantiomerically active form of Folinic Acid (also known as 5-formyl tetrahydrofolic acid or leucovorin). Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary isomers, while levoleucovorin contains only the pharmacologically active levo-isomer. In vitro, the levo-isomer has been shown to be...
Approved
Investigational
Matched Synonyms: … N-[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic …
Matched Iupac: … (2S)-2-{[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido …
Matched Salts cas: … 419573-16-3 …
Matched Iupac: … (2S)-2-{[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido …
Matched Salts cas: … 419573-16-3 …
Pentamidine
Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of pneumocystis pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
Approved
Investigational
Matched Synonyms: … 1,5-bis(4-amidinophenoxy)pentane …
Matched Iupac: … 4-{[5-(4-carbamimidoylphenoxy)pentyl]oxy}benzene-1-carboximidamide …
Matched Iupac: … 4-{[5-(4-carbamimidoylphenoxy)pentyl]oxy}benzene-1-carboximidamide …
Aminohippuric acid
The glycine amide of 4-aminobenzoic acid. Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity. [PubChem]
Approved
Investigational
Matched Synonyms: … 4-aminohippuric acid …
Matched Iupac: … 2-[(4-aminophenyl)formamido]acetic acid …
Matched Description: … The glycine amide of 4-aminobenzoic acid. …
Matched Iupac: … 2-[(4-aminophenyl)formamido]acetic acid …
Matched Description: … The glycine amide of 4-aminobenzoic acid. …
Talquetamab
Talquetamab is a IgG4-PAA bispecific G protein-coupled receptor class C group 5 member D (GPRC5D)-directed CD3 T-cell engager. It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each arm comprising a heavy and light chain. Talquetamab binds to GPRC5D, a cell surface...
Approved
Investigational
Matched Synonyms: … 240-ALANINE,410-LEUCINE,414-LYSINE), ANTI-(HUMAN CD3 ANTIGEN) (HUMAN MONOCLONAL JNJ-63483043 .GAMMA.4- ... PROTEIN-COUPLED RECEPTOR CLASS C GROUP 5 MEMBER D)), AND ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4) ... PROTEIN-COUPLED RECEPTOR CLASS C GROUP 5 MEMBER D)), AND ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4) …
Tamoxifen
Tamoxifen is a non-steroidal antiestrogen used to treat estrogen receptor positive breast cancers as well as prevent the incidence of breast cancer in high risk populations.[A1025,L7799,L7802] Tamoxifen is used alone or as an adjuvant in these treatments.[L7799,L7802] Tamoxifen may no longer be the preferred treatment for these types of cancers...
Approved
Matched Synonyms: … (Z)-2-(4-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethanamine …
Matched Iupac: … (2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethyl)dimethylamine …
Matched Iupac: … (2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethyl)dimethylamine …
Rosiglitazone
Rosiglitazone is an anti-diabetic drug in the thiazolidinedione class of drugs. It is marketed by the pharmaceutical company GlaxoSmithKline as a stand-alone drug (Avandia) and in combination with metformin (Avandamet) or with glimepiride (Avandaryl). Like other thiazolidinediones, the mechanism of action of rosiglitazone is by activation of the intracellular receptor...
Approved
Investigational
Matched Synonyms: … (RS)-5-{4-[2-(Methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedion …
Matched Iupac: … 5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)methyl]-1,3-thiazolidine-2,4-dione …
Matched Iupac: … 5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)methyl]-1,3-thiazolidine-2,4-dione …
Ximelagatran
Ximelagatran is an anticoagulant intended to become a replacement for warfarin by overcoming the dietary restrictions, drug interaction, and monitoring issues associated with the former. In 2006, its manufacturer AstraZeneca announced that it would not attempt to market ximelagatran after reports of hepatotoxicity (liver damage) during trials, and to discontinue...
Approved
Investigational
Withdrawn
Matched Synonyms: … ethyl 2-[[(1R)-1-cyclohexyl-2- [(2S)-2-[[4-(N'-hydroxycarbamimidoyl) phenyl]methylcarbamoyl]azetidin- …
Matched Iupac: … ethyl 2-{[(1R)-1-cyclohexyl-2-[(2S)-2-[({4-[(Z)-N'-hydroxycarbamimidoyl]phenyl}methyl)carbamoyl]azetidin …
Matched Iupac: … ethyl 2-{[(1R)-1-cyclohexyl-2-[(2S)-2-[({4-[(Z)-N'-hydroxycarbamimidoyl]phenyl}methyl)carbamoyl]azetidin …
Vigabatrin
Vigabatrin is an analog of gamma-aminobutyric acid (GABA), the main inhibitory neurotransmitter in the central nervous system, used in the treatment of refractory seizures and infantile spasms. It irreversibly inhibits the enzyme responsible for GABA metabolism, thereby increasing levels of circulating GABA. Although administered as a racemic mixture, only the...
Approved
Matched Synonyms: … 4-Amino-5-hexenoic acid …
Matched Iupac: … 4-aminohex-5-enoic acid …
Matched Iupac: … 4-aminohex-5-enoic acid …
Displaying drugs 251 - 275 of 11279 in total