Displaying drugs 251 - 275 of 5748 in total
Flunisolide
Flunisolide (marketed as AeroBid, Nasalide, Nasarel) is a corticosteroid with anti-inflammatory actions. It is often prescribed as treatment for allergic rhinitis and its principle mechanism of action involves activation of glucocorticoid receptors.
Approved
Investigational
Matched Iupac: … (1S,2S,4R,8S,9S,11S,12S,13R,19S)-19-fluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo …
Matched Salts cas: … 77326-96-6 …
Matched Salts cas: … 77326-96-6 …
Flurandrenolide
A corticosteroid used topically in the treatment of various skin disorders. It is usually employed as a cream or an ointment, and is also used as a polyethylene tape with an adhesive. (From Martindale, The Extra Pharmacopoeia, 30th ed, p733)
Approved
Matched Iupac: … (1S,2S,4R,8S,9S,11S,12S,13R,19S)-19-fluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo …
Pralsetinib
Pralsetinib, similar to the previously approved selpercatinib, is a kinase inhibitor with enhanced specificity for RET tyrosine kinase receptors (RTKs) over other RTK classes.[A202055, A219751, L15986] Enhanced RET (Rearranged during transfection) oncogene expression is a hallmark of many cancers, including non-small cell lung cancer. Although multikinase inhibitors, including cabozantinib, ponatinib,...
Approved
Investigational
Matched Iupac: … (1s,4s)-N-[(1S)-1-[6-(4-fluoro-1H-pyrazol-1-yl)pyridin-3-yl]ethyl]-1-methoxy-4-{4-methyl-6-[(5-methyl …
Pentoxifylline
Pentoxifylline (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties of blood and also has both anti-oxidant and anti-inflammatory properties.[A226415, L30300] Although originally developed to treat intermittent claudication, a form of exertion-induced leg pain common in patients with peripheral arterial disease, PTX has been investigated for its possible...
Approved
Investigational
Matched Description: … [A226410, A226415, A226455] More recently, PTX has been suggested as a possible treatment for COVID-19 …
Matched Products: … HEMOPENE 100 MG 5 ML 10 AMPUL …
Matched Products: … HEMOPENE 100 MG 5 ML 10 AMPUL …
Caffeine
Caffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and to combat drowsiness. Caffeine is similar in chemical structure to Theophylline and Theobromine.[A187691,L9851] It can be sourced from coffee beans, but also occurs naturally in...
Approved
Matched Description: … This correlates to about 1 in 10 births. …
Matched Mixtures name: … GRIPAL 500/30 MG TABLET, 10 TABLET ... THOMAPVRIN 250 mg/200 mg/50 mg TABLET, 10 ADET ... GERALGINE-K 500 MG/30 MG/10 MG TABLET, 20 ADET …
Matched Products: … PEYONA 20MG/ML INFÜZYONLUK VE ORAL ÇÖZELTI, 10 AMPUL ... SITAFEIN 20 MG / ML INFÜZYONLUK / ORAL ÇÖZELTİ, 10 ADET ... KAFSİTON 60 MG/3 ML İNFÜZYONLUK VE ORAL ÇÖZELTİ, 10 ADET …
Matched Mixtures name: … GRIPAL 500/30 MG TABLET, 10 TABLET ... THOMAPVRIN 250 mg/200 mg/50 mg TABLET, 10 ADET ... GERALGINE-K 500 MG/30 MG/10 MG TABLET, 20 ADET …
Matched Products: … PEYONA 20MG/ML INFÜZYONLUK VE ORAL ÇÖZELTI, 10 AMPUL ... SITAFEIN 20 MG / ML INFÜZYONLUK / ORAL ÇÖZELTİ, 10 ADET ... KAFSİTON 60 MG/3 ML İNFÜZYONLUK VE ORAL ÇÖZELTİ, 10 ADET …
Sofosbuvir
Sofosbuvir (tradename Sovaldi) is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the...
Approved
Matched Description: … Approved in October 2014 by the FDA, Harvoni is indicated for the treatment of HCV genotypes 1, 4, 5, and 6 …
Chloroquine
Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. It was the drug of choice to treat malaria until the development of newer antimalarials such as pyrimethamine, artemisinin, and mefloquine. Chloroquine and its derivative hydroxychloroquine have since been repurposed for the treatment of a...
Approved
Investigational
Vet approved
Matched Description: … FDA emergency use authorization for [hydroxychloroquine] and chloroquine in the treatment of COVID-19 …
Matched Categories: … Experimental Unapproved Treatments for COVID-19 …
Matched Products: … KUTLU 250 MG FİLM KAPLI TABLET, 10 ADET ... OROQUİNE 250 MG/5 ML IV İNFÜZYONLUK ÇÖZELTİ , 10 ADET …
Matched Categories: … Experimental Unapproved Treatments for COVID-19 …
Matched Products: … KUTLU 250 MG FİLM KAPLI TABLET, 10 ADET ... OROQUİNE 250 MG/5 ML IV İNFÜZYONLUK ÇÖZELTİ , 10 ADET …
Triflupromazine
A phenothiazine used as an antipsychotic agent and as an antiemetic.
Approved
Vet approved
Matched Synonyms: … 10-(3-(Dimethylamino)propyl)-2-(trifluoromethyl)phenothiazine ... 2-Trifluoromethyl-10-(gamma-dimethylaminopropyl)phenothiazine …
Matched Iupac: … dimethyl({3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl})amine …
Matched Iupac: … dimethyl({3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl})amine …
Nortriptyline
Nortriptyline hydrochloride, the active metabolite of amitriptyline, is a tricyclic antidepressant (TCA). It is used in the treatment of major depression and is also used off-label for chronic pain and other conditions.
Approved
Matched Products: … ออทริพ 10 ... เอ็น-ทริป 10 ... นูทริพ(10 มก.) …
Lypressin
Approved
Matched Iupac: … (2S)-6-amino-2-({[(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-13-benzyl-6,9,12,15,18-pentahydroxy-10-[2- …
Lopinavir
Lopinavir is an antiretroviral protease inhibitor used in combination with other antiretrovirals in the treatment of HIV-1 infection. Lopinavir is marketed and administered exclusively in combination with ritonavir - this combination, first marketed by Abbott under the brand name Kaletra in 2000, is necessary due to lopinavir's poor oral bioavailability...
Approved
Matched Description: … Lopinavir was previously under investigation in combination with ritonavir for the treatment of COVID-19 …
Matched Mixtures name: … LOPIMUNE ® + RITONAVIR 10 MG - PELLETS EN CÁPSULAS ORALES …
Matched Categories: … Experimental Unapproved Treatments for COVID-19 …
Matched Mixtures name: … LOPIMUNE ® + RITONAVIR 10 MG - PELLETS EN CÁPSULAS ORALES …
Matched Categories: … Experimental Unapproved Treatments for COVID-19 …
Strontium ranelate
Strontium ranelate, a strontium (II) salt of ranelic acid, is a medication for osteoporosis. Some reports have shown that strontium ranelate can slow down the progression of osteoarthritis of the knee. This agent presents an atypical mechanism of action in which it increases deposition of new bone by osteoblasts and,...
Approved
Withdrawn
Milk thistle
Milk thistle is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Investigational
Collagenase clostridium histolyticum
Collagenase clostridium histolyticum is an enzyme produced by the bacterium Clostridium histolyticum. It is beneficial in the breakdown of collagen plaques for the treatment of Dupuytren's contracture and Peyronie's disease. The topical formulation is used for the debridement of necrotic tissue due to burns or chronic ulcers. On July 6,...
Approved
Investigational
Matched Description: … [L14912]
On July 6, 2020 a combination of injectable bacterial collagenases was approved by the FDA …
Icodextrin
Icodextrin is an iso-osmotic peritoneal dialysis solution containing glucose polymers. It is used primarily for ambulatory peritoneal dialysis (CAPD) of diabetic patients and automated peritoneal dialysis (APD) for patients with end-stage renal disease. It is injected as a solution into the peritoneal cavity. The drug is absorbed via convective transport...
Approved
Investigational
Terbinafine
Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell...
Approved
Investigational
Vet approved
Valoctocogene roxaparvovec
Valoctocogene roxaparvovec is an adeno-associated virus serotype 5 (AAV5) based gene therapy vector that expresses the B-domain deleted SQ form of human coagulation factor VIII (hFVIII-SQ). The expression of hFVIII-SQ is driven by a liver-specific promoter, which enables hepatocytes to produce factor VIII protein and increase the levels of active...
Approved
Investigational
Ascorbic acid
A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic...
Approved
Nutraceutical
Matched Mixtures name: … DAYCOLD-HOT 500/10/15/100 MG SAŞE,6 SAŞE ... Mvc 9+4 Inj ... Mvc 9 Plus 3 Inj …
Matched Products: … Vitamin C 10 % ... FORDRAY 250 MG VAJİNAL TABLET, 6 ADET ... CEVIMAX 1000 MG EFERVESAN TABLET, 10 ADET …
Matched Products: … Vitamin C 10 % ... FORDRAY 250 MG VAJİNAL TABLET, 6 ADET ... CEVIMAX 1000 MG EFERVESAN TABLET, 10 ADET …
Isoniazid
Antibacterial agent used primarily as a tuberculostatic. It remains the treatment of choice for tuberculosis.
Approved
Investigational
Matched Mixtures name: … TB VIT 6 …
Perflexane
Approved
Octreotide
Acromegaly is a disorder caused by excess growth hormone (GH), increasing the growth of body tissues and causing metabolic dysfunction. In most cases, it results from an anterior pituitary growth hormone-releasing tumor. Typically, the feet, hands, and face grow abnormally large; organomegaly and insulin resistance may also occur. Acromegaly is...
Approved
Investigational
Matched Products: … SANDOSTATIN LAR 10 MG ... SANDOSTATIN LAR FOR INJECTION 10 mg ... SANDOSTATIN LAR 10 MG ENJEKSİYONLUK SÜSPANSİYON İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET …
Imipramine
Imipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, imipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, imipramine exerts...
Approved
Matched Products: … มินาพีน 10 ... IMIPRAMINA 10 MG ... IMIPRAMIN-NEURAX 10 MG …
Darunavir
Darunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as ritonavir for the effective management of HIV-1 infection. As a second-generation protease inhibitor, darunavir is designed to combat resistance to standard HIV therapy.[A2278,A2281] It was initially approved by the FDA in 2006. Darunavir is being...
Approved
Matched Description: … Darunavir is being studied as a possible treatment for SARS-CoV-2, the coronavirus responsible for COVID-19 …
Matched Categories: … Experimental Unapproved Treatments for COVID-19 …
Matched Categories: … Experimental Unapproved Treatments for COVID-19 …
Setmelanotide
Setmelanotide is the first available treatment for patients with pro-opiomelanocortin, proprotein subilisin/kexin type 1, or leptin deficiencies. It is an agonist of the melanocortin 4 receptor. Earlier attempts at agonizing MC4R (such as LY2112688) lead to successful weight loss, but also an increase in blood pressure and heart rate. Other...
Approved
Investigational
Matched Iupac: … 4R,7S,10S,13R,16S,19R,22R)-13-benzyl-22-[(2S)-5-[(diaminomethylidene)amino]-2-acetamidopentanamido]-10 ... -{3-[(diaminomethylidene)amino]propyl}-16-[(1H-imidazol-5-yl)methyl]-7-[(1H-indol-3-yl)methyl]-19-methyl …
Matched Description: … [A224449] Imcivree was granted EMA orphan designation on November 19, 2018 [L24559] and FDA approval …
Matched Salts cas: … 1504602-49-6 …
Matched Description: … [A224449] Imcivree was granted EMA orphan designation on November 19, 2018 [L24559] and FDA approval …
Matched Salts cas: … 1504602-49-6 …
Omaveloxolone
Omaveloxolone (RTA-408) is a semisynthetic oleanane triterpenoid with antioxidant and anti-inflammatory properties.[A257534,A257539] Omaveloxolone acts as an activator of nuclear factor (erythroid-derived 2)-like 2 (Nrf2), a transcription factor that mitigates oxidative stress. In patients with Friedreich's ataxia, a genetic disease involving mitochondrial dysfunction, the Nrf2 pathway is impaired, and Nrf2 activity...
Approved
Investigational
Displaying drugs 251 - 275 of 5748 in total