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Displaying drugs 251 - 275 of 3307 in total
Zenocutuzumab is under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy in HER2+ and With Endocrine Therapy in ER+ and Low HER2 Breast Cancer).
Investigational
Matched Synonyms: … Immunoglobulin g1, bispecific, anti-(human epidermal growth factor receptors, her2 and her3) (humanized ... antibody with enhanced antibody-dependent cell-mediated cytotoxicity (adcc) activity targeting her2 and
Matched Description: … With Endocrine Therapy in ER+ and Low HER2 Breast Cancer). ... under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy in HER2+ and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Muparfostat (PI-88) is a mixture of highly sulfated, monophosphorylated mannose oligosaccharides, derived from the extracellular phosphomannan of the yeast Pichia (Hansenula) holstii, with potential antiangiogenic activity.
Investigational
Matched Synonyms: … Phosphomannopentaose sulfate ... Mannopentaose phosphate sulfate ... Sulfated mannopentaose phosphate …
Matched Iupac: … methyl]oxan-3-yl]oxy}oxan-4-yl]oxy}-6-[(phosphonooxy)methyl]-4,5-bis(sulfooxy)oxan-3-yl)oxidanesulfonic acid
Matched Description: … Muparfostat (PI-88) is a mixture of highly sulfated, monophosphorylated mannose oligosaccharides, derived …
Matched Salts name: … Muparfostat sodium
Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex. Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions.[L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone. Hydrocortisone was granted FDA approval on 5 August 1952.
Approved
Vet approved
Matched Description: … [A188387] Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions. ... [L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named …
Matched Mixtures name: … Neomycin and Polymyxin B Sulfates, Bacitracin Zinc and Hydrocortisone ... Hydrocortisone and Acetic Acid ... Neomycin and Polymyxin B Sulfates, Bacitracin Zinc and Hydrocortisone …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Medications that reduce magnesium levels ... Corticosteroids for Systemic Use ... Corticosteroids for Systemic Use, Plain ... Corticosteroids for Local Oral Treatment …
Matched Products: … HYDROCORTISON ACIS 10MG ... Healerz for Itches ... Rodan and Fields Soothe …
Investigational
Matched Synonyms: … Flt3 ligand, IL-7, IL-15 and IL-2 to generate the NK cell ... The cells are expanded and differentiated in the presence of cytokines including thrombopoietin, SCF, …
Investigational
Matched Synonyms: … engager antibody with a single chain fc moiety that binds to b cell maturation antigen surface receptor and
Povidone-iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It contains from 9.0% to 12.0% available iodine, calculated on a dry basis. This unique complex was discovered in 1955 at the Industrial Toxicology Laboratories in Philadelphia by H. A. Shelanski and M. V. Shelanski. During in...
Approved
Matched Description: … Shelanski and M. V. Shelanski. ... Povidone-iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine ... Povidone-iodine was immediately marketed, and has since become the universally preferred iodine antiseptic …
Matched Mixtures name: … Physician EZ Use Joint Tunnel and Trigger Kit ... Skin Antisepsis, Oral Cleansing and Nasal Antisepsis System ... JTT Physicians Joint, Tunnel and Trigger …
Matched Categories: … Antiseptics and Disinfectants ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Betadine Shampoo for Dry Hair 4% ... Fresh and Pure ... 3M Skin and Nasal Antiseptic …
Sodium Sulfate Anhydrous is the anhydrous, sodium salt form of sulfuric acid. Sodium sulfate anhydrous disassociates in water to provide sodium ions and sulfate ions. Sodium ion is the principal cation of the extracellular fluid and plays a large part in the therapy of fluid and electrolyte disturbances. Sodium sulfate...
Approved
Vet approved
Matched Synonyms: … Sulfuric acid disodium salt, anhydrous ... Anhydrous sodium sulfate ... Sodium sulfate anhydrous …
Matched Name: … Sodium sulfate
Matched Iupac: … disodium sulfate
Matched Description: … Sodium Sulfate Anhydrous is the anhydrous, sodium salt form of sulfuric acid. ... Sodium sulfate anhydrous disassociates in water to provide sodium ions and sulfate ions. ... Sodium sulfate anhydrous is an electrolyte replenisher and is used in isosmotic solutions so that administration …
Matched Mixtures name: … Sodium polysulthionate and folic acid ... Sodium Polysulthionate and Folic Acid ... Peg-3350, Sodium Sulfate, Sodium Chloride, Potassium Chloride, Sodium Ascorbate and Ascorbic Acid
Matched Salts name: … Sodium sulfate decahydrate …
Matched Categories: … sodium sulfate ... sodium sulfate ... Alimentary Tract and Metabolism ... Drugs for Constipation ... Sulfur Acids
A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2 (B2 CAS # 9060-10-0). It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. Bleomycin A2 is used as the representative structure for Bleomycin.
Approved
Investigational
Matched Description: … It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. ... of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and ... Bleomycin A2 is used as the representative structure for Bleomycin. …
Matched Salts name: … Bleomycin sulfate ... Bleomycin hydrochloride
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … DBL™ BLEOMYCIN SULFATE FOR INJECTION 15 units ... BIXEL (BLEOMYCIN SULPHATE FOR INJECTION 15 UNITS) ... DBL BLEOMYCIN SULFATE FOR INJECTION 15000 iu/vial …
Oxymetazoline is an imidazole derivative and a potent, direct-acting alpha (α)-adrenergic agonist with affinity to both α1- and α2-adrenoceptors. Oxymetazoline is available in various formulations with a wide variety of clinical implications. The topical formulation of the drug is used to treat persistent facial redness in adults. As an effective...
Approved
Investigational
Matched International brands: … Vicks Sinex 12 Hour Ultra Fine Mist for Sinus Relief …
Matched Description: … is used for regional anesthesia during dental procedures in children and adults. ... adults with acquired blepharoptosis, or ptosis, making it the first FDA-approved medical treatment for ... affinity to both α1- and α2-adrenoceptors. …
Matched Mixtures name: … Mucinex Sinus-Max Pressure, Pain and Cough and Mucinex Sinus-Max Severe Congestion Relief Clear and Cool …
Matched Salts name: … Oxymetazoline hydrochloride
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Mucinex Full Force ... Mucinex Sinus-Max Full Force ... ILIADIN SOLUTION FOR NOSE 0.01% …
Cetirizine, also commonly known as Zyrtec, is an orally active second-generation histamine H1 antagonist proven effective in the treatment of various allergic symptoms, such as sneezing, coughing, nasal congestion, hives, and other symptoms , . One of the most common uses for this drug is for a condition called allergic...
Approved
Matched Iupac: … 2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid
Matched Description: … with sleep, and other difficulties with day to day activities for many individuals [A175057]. ... in the treatment of various allergic symptoms, such as sneezing, coughing, nasal congestion, hives, and ... prevalence of allergic rhinitis in the United States is about 15% according to physician diagnoses, and
Matched Mixtures name: … FORT-GRIP ... Cetirizine Hydrochloride and Pseudoephedrine Hydrochloride ... Cetirizine Hydrochloride and Pseudoephedrine Hydrochloride
Matched Salts name: … Cetirizine hydrochloride
Matched Categories: … Antihistamines for Systemic Use ... Cetirizine and isomer ... Decongestants and Antiallergics …
Matched Products: … Berkley and Jensen Cetirizine Hydrochloride ... Berkley and Jensen Childrens Cetirizine Hydrochloride ... ZINE
Talquetamab is a IgG4-PAA bispecific G protein-coupled receptor class C group 5 member D (GPRC5D)-directed CD3 T-cell engager. It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each arm comprising a heavy and light chain. Talquetamab binds to GPRC5D, a cell surface...
Approved
Investigational
Matched Synonyms: … -KAPPA/G4-LAMBDA, ANTI-(HOMO SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP 5 MEMBER D)), AND ... ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), HUMANIZED AND CHIMERIC MONOCLONAL ANTIBODY, BISPECIFIC ... -KAPPA/G4-LAMBDA, ANTI-(HOMO SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP 5 MEMBER D)), AND
Matched Description: … arm comprising a heavy and light chain. ... It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each ... Talquetamab binds to GPRC5D, a cell surface receptor expressed predominantly on multiple myeloma cells, and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Glycerol monostearate, commonly known as GMS, is the glycerol ester of stearic acid . It is commonly used as an emulsifier in foods.
Experimental
Matched Synonyms: … Geleol mono and diglycerides ... Stearic acid, monoester with glycerol …
Matched Description: … Glycerol monostearate, commonly known as GMS, is the glycerol ester of stearic acid . …
Suratadenoturev is a gene-modified oncolytic adenovirus expressing the telomerase reverse transcriptase gene.
Investigational
Matched Synonyms: … -5) in which the E1 gene, including its normal transcriptional regulatory element, has been deleted and ... telomerase reverse transcriptase (hTERT) and IRES, respectively. ... A replication-competent adenovirus type 5 in which the E1A and E1B genes are under the control of a human …
Experimental
Matched Synonyms: … Cysteinyl-S-sulfonic acid ... Cysteine-S-sulfate ... Cysteine-S-sulfonate
Matched Iupac: … (2R)-2-amino-3-(sulfosulfanyl)propanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Neutral ... Amino Acids, Sulfur …
Lanolin is a yellow fat obtained from sheep's wool. It is used as an emollient, cosmetic, and pharmaceutic aid . The US federal code of regulations states that lanolin in the concentration range of 12-50% may be included in over the counter skin ointments . Lanolin is the purified, secreted...
Approved
Matched Description: … Lanolin is also frequently used in protective baby skin treatment and for sore nipples in breastfeeding ... It is used as an emollient, cosmetic, and pharmaceutic aid [L2580]. ... For this reason, it is also called wool wax or wool grease. …
Matched Mixtures name: … Kendra SKIN PROTECTION and PAIN RELIEF FOR HAIR REMOVAL ... Skullduggery Pain Relief and Skin Protection for Tattoos ... Vitamins A and D Diaper Rash …
Matched Categories: … Basic Ointments and Protectants …
Matched Products: … Soothe and Cool Free Medseptic Skin Protectant …
AB-201 is a CAR-NK cell therapy targeted against HER2. It is under investigation for the treatment of HER2-positive cancers, including breast and gastric carcinomas.
Investigational
Matched Synonyms: … allogeneic cord blood-derived NK cells that have been genetically modified to express a HER2-directed CAR and
Matched Description: … [L48340] It is under investigation for the treatment of HER2-positive cancers, including breast and gastric …
OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human gp91phox gene. It is being investigated for the treatment of X-linked chronic granulomatous disease.
Investigational
Matched Synonyms: … Autologous CD34+ enriched cell population that contains hematopoietic stem and progenitor cells transduced …
Matched Description: … OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells ... It is being investigated for the treatment of X-linked chronic granulomatous disease. …
Haemophilus influenzae type b strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen is an active immunization as a booster dose given intramuscularly to pediatric patients who have received a primary series with a Haemophilus b Conjugate Vaccine that is licensed for primarly immunization. The vaccine contains Haemophilus b capsular polysaccharide...
Approved
Investigational
Matched Synonyms: … Haemophilus influenzae type B-PRP and tetanus toxoid conjugate (PRP-T) …
Matched Description: … These are heat inactivated and purified. ... patients who have received a primary series with a Haemophilus b Conjugate Vaccine that is licensed for
Thrombotic thrombocytopenic purpura (TTP) is a rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and various degrees of organ damage. It may be inherited (congenital TTP; cTTP) or acquired due to autoantibodies (immune-mediated TTP; iTTP), although cTTP accounts for <5% of all cases of TTP. Patients with cTTP...
Approved
Investigational
Matched Synonyms: … Recombinant disintegrin and metalloprotease with thrombospondin type 1 motifs …
Matched Description: … rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and ... Patients with cTTP have a severe deficiency of a plasma metalloproteinase called ADAMTS13 (a disintegrin and ... large von Willebrand factor multimers and preventing the formation of microthrombi - this deficiency …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Blood and Blood Forming Organs ... apadamtase alfa and cinaxadamtase alfa …
Octinoxate is a cinnamate ester and common ingredient in sunscreen and other skin care products to minimize DNA photodamage. It was originally developed in 1950's as an organic UV-B filter that absorbs UV-B rays from sun. It is often combined with nanoparticles or other water-resistant liposomes in formulations to increase...
Approved
Investigational
Matched Description: … Octinoxate is a cinnamate ester and common ingredient in sunscreen and other skin care products to minimize ... Its use in pharmaceutical and cosmetic formulations is approved by FDA. ... nanoparticles or other water-resistant liposomes in formulations to increase the localization at the epidermis and
Matched Mixtures name: … Sodium Sulfacetamide and Sulfur ... Solar Sense Clear Zinc For Face And Lips SPF 50 ... Solar Sense Clear Zinc For Face Sunscreen SPF 70 …
Matched Categories: … Emollients and Protectives ... Protectives Against UV-Radiation for Topical Use ... Carboxylic Acids ... Acids, Carbocyclic …
Matched Products: … Resilience Lift Firming Sculpting Face and Neck Spf15 for Dry Skin ... Estee Lauder Resilience Lift Firming/sculpting Face and Neck CRème SPF 15 for Dry Skin ... Lancome Paris Absolue Makeup Broad Spectrum SPF 20 Sunscreen Absolute Replenishing Makeup for Dry and
Bacitracin is a combination of at least 9 bacitracins.[A955,A181952] 60-80% of commercially prepared bacitracin is bacitracin A. The bacillus that produces bacitracin was first isolated from a knee scrape in 1945 from the knee wound of a child named Margaret Tracy. Bacitracin was granted FDA approval on 29 July 1948.[A181997,L7748]
Approved
Vet approved
Matched Iupac: … heptaoxo-1,4,7,10,13,16,19-heptaazacyclopentacosan-21-yl]carbamoyl}-2-methylbutyl]carbamoyl}butanoic acid
Matched Mixtures name: … Bacitracin Zinc and Polymyxin B Sulfate ... Polysporin for Stitches ... Bacitracin Zinc and Polymyxin B Sulfate
Matched Salts name: … Bacitracin zinc
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antibiotics for Topical Use ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use ... Acids, Carbocyclic …
Matched Products: … Up and Up First Aid Antibiotic ... Up and Up Bacitracin first aid ... Bacitracin for Injection …
Atidarsagene autotemcel, sold under the brand name Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene. Libmeldy was granted orphan designation by the EMA in April 2007, and was...
Approved
Matched Synonyms: … Autologous CD34+ cells transduced with lentiviral vector which encodes for the aryl Sulfatase A complimentary ... Autologous CD34+ cell enriched population that contains haematopoietic stem and progenitor cells (HSPC ... deoxyribonucleic acid sequence …
Matched Description: … Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and ... [L45191] Libmeldy was granted orphan designation by the EMA in April 2007, and was issued a marketing ... authorization in the EU in December 2020 for the treatment of certain manifestations of metachromatic …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Calcium carbonate is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. Subsequent increases in pH may inhibit the action of pepsin. An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects. Calcium carbonate may also...
Approved
Investigational
Matched Synonyms: … Carbonic acid calcium salt (1:1) …
Matched Description: … It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. ... An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects. …
Matched Mixtures name: … PNV Ferrous Fumarate Docusate Folic Acid ... Calcium and Magnesium With Zinc ... Calcium and Magnesium W Zinc Tab …
Matched Categories: … Drugs for Acid Related Disorders ... ascorbic acid (vit C) and calcium ... Alimentary Tract and Metabolism ... Antacids and Adsorbents ... Carbonic Acid
Matched Products: … ACID STOP ... Only For ANTACID ... Formu Care Calcium Antacid …
Investigational
Matched Synonyms: … 3-butylidenephthalide, mixture of cis and trans isomers …
Matched Categories: … Phthalic Acids ... Acids, Carbocyclic ... Carboxylic Acids
OTL-203 is an autologous CD34+ enriched cell therapy that contains hematopoietic stem and progenitor cells transduced ex-vivo using a lentiviral vector encoding alpha-L-iduronidase gene.
Investigational
Matched Synonyms: … Autologous CD34+ enriched cell population that contains hematopoietic stem and progenitor cells transduced …
Matched Description: … OTL-203 is an autologous CD34+ enriched cell therapy that contains hematopoietic stem and progenitor …
Displaying drugs 251 - 275 of 3307 in total