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Displaying drugs 251 - 275 of 15153 in total

Docetaxel

Docetaxel is a clinically well established anti-mitotic chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and non-small cell lung cancer. Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of paclitaxel.[A259676,L46466] Docetaxel reversibly binds to microtubulin with high affinity in a 1:1 stoichiometric...
Approved
Investigational
Matched Description: … Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of [paclitaxel]. ... chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and ... microtubulin with high affinity in a 1:1 stoichiometric ratio, allowing it to prevent cell division and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Oncotaxel Concentrate and solvent for solution for infusion 40 mg/ ml …

Lercanidipine

Lercanidipine is a calcium channel blocker of the dihydropyridine class. It is sold under various commercial names including Zanidip.
Approved
Investigational
Matched Iupac: … 3-{1-[(3,3-diphenylpropyl)(methyl)amino]-2-methylpropan-2-yl} 5-methyl 2,6-dimethyl-4-(3-nitrophenyl) …
Matched Categories: … valsartan and lercanidipine ... enalapril and lercanidipine ... ACE Inhibitors and Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers …

Amifostine

A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
Approved
Investigational
Matched Description: … It causes splenic vasodilation and may block autonomic ganglia. …

Acenocoumarol

Acenocoumarol is a coumarin derivative used as an anticoagulant. Coumarin derivatives inhibit the reduction of vitamin K by vitamin K reductase. This prevents carboxylation of vitamin K-dependent clotting factors, II, VII, IX and X, and interferes with coagulation. Hematocrit, hemoglobin, international normalized ratio and liver panel should be monitored. Patients...
Approved
Investigational
Matched Description: … This prevents carboxylation of vitamin K-dependent clotting factors, II, VII, IX and X, and interferes ... [A188739] Hematocrit, hemoglobin, international normalized ratio and liver panel should be monitored. …
Matched Categories: … Warfarin and isomers ... Blood and Blood Forming Organs …

Methylprednisolone hemisuccinate

A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.
Approved
Matched Description: … A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …

Vincristine

Vincristine is an antitumor vinca alkaloid isolated from Vinca Rosea. It is marketed under several brand names, many of which have different formulations such as Marqibo (liposomal injection) and Vincasar. Vincristine is indicated for the treatment of acute leukaemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis. vincristine sulfate...
Approved
Investigational
Matched Iupac: … methyl (1R,9R,10S,11R,12R,19R)-11-(acetyloxy)-12-ethyl-4-[(1R,13S,15R,17S)-17-ethyl-17-hydroxy-13-(methoxycarbonyl …
Matched Description: … several brand names, many of which have different formulations such as Marqibo (liposomal injection) and ... part of polychemotherapy because of lack of significant bone–marrow suppression (at recommended doses) and ... indicated for the treatment of acute leukaemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Aurothioglucose

Aurothioglucose, also known as gold thioglucose, was formerly used to treat rheumatoid arthritis. Contemporary research on the effect of gold salts treatment began in 1935, primarily to reduce inflammation and to slow disease progression in patients with rheumatoid arthritis . The use of gold compounds has decreased since the 1980s...
Approved
Withdrawn
Matched Description: … use of gold compounds has decreased since the 1980s owing to numerous side effects, limited efficacy, and ... Contemporary research on the effect of gold salts treatment began in 1935, primarily to reduce inflammation and ... replaced with the use of various current disease modifying anti-rheumatic drugs (DMARDs) like methotrexate and …
Matched Categories: … Antiinflammatory and Antirheumatic Products …

Lisinopril

Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and myocardial infarction.[L8384,L8387,L8390] Lisinopril and captopril are the only ACEIs that are not prodrugs. It functions by inhibition of angiotensin converting enzyme as well as the renin angiotensin aldosterone system.[A184781,A184808,A184817] ACEIs are commonly used as a...
Approved
Investigational
Matched Description: … [L8384,L8387,L8390] Lisinopril and [captopril] are the only ACEIs that are not prodrugs. ... Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and …
Matched Mixtures name: … Lisinopril and HCTZ ... Lisinopril and Hydrochlorothiazide ... Lisinopril and Hydrochlorothiazide …
Matched Categories: … ACE Inhibitors and Diuretics ... lisinopril and diuretics ... lisinopril and amlodipine ... Amino Acids, Peptides, and Proteins ... ACE Inhibitors and Calcium Channel Blockers …

Glipizide

Glipizide is an oral hypoglycemic agent in the second-generation sulfonylurea drug class that is used to control blood sugar levels in patients with type 2 diabetes mellitus. It was first introduced in 1984 and is available in various countries including Canada and the U.S. According to the 2018 Clinical Practice...
Approved
Investigational
Matched Description: … It was first introduced in 1984 [A179491] and is available in various countries including Canada and ... [A179485] Glipizide was first approved by the FDA in 1994 and is available in extended-release tablets ... onset of action with the shortest half-life and duration of action, reducing the risk for long-lasting …
Matched Mixtures name: … Glipizide and Metformin HCl ... Glipizide and Metformin HCl ... Glipizide and Metformin Hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism …

Buprenorphine

Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist used for the treatment of severe pain.[A186283,A186292] It is also commonly used as an alternative to methadone for the treatment of severe opioid addiction. Buprenorphine is commercially available as the brand name product Suboxone which is...
Approved
Illicit
Investigational
Vet approved
Matched Description: … who require larger and more frequent doses. ... an improved safety profile with a lower risk of overdose and respiratory depression. ... Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist …
Matched Mixtures name: … Buprenorphine and Naloxone ... Buprenorphine and Naloxone ... Buprenorphine and Naloxone …

Glyburide

Glyburide is a second generation sulfonylurea used to treat patients with diabetes mellitus type II. It is typically given to patients who cannot be managed with the standard first line therapy, metformin. Glyburide stimulates insulin secretion through the closure of ATP-sensitive potassium channels on beta cells, raising intracellular potassium and...
Approved
Matched Description: … through the closure of ATP-sensitive potassium channels on beta cells, raising intracellular potassium and …
Matched Mixtures name: … Glyburide and Metformin ... Glyburide and Metformin ... Glyburide and Metformin …
Matched Categories: … Alimentary Tract and Metabolism …

Amphetamine

Amphetamine, a compound discovered over 100 years ago, is one of the more restricted controlled drugs. It was previously used for a large variety of conditions and this changed until this point where its use is highly restricted. Amphetamine, with the chemical formula alpha-methylphenethylamine, was discovered in 1910 and first...
Approved
Illicit
Investigational
Matched Description: … Amphetamine structure presents one chiral center and it exists in the form of dextro- and levo-isomers ... After being proven to reduce drug-induced anesthesia and produce arousal and insomnia, amphetamine racemic ... mix was registered by Smith, Kline and French in 1935. …
Matched Mixtures name: … Dextroamphetamine Saccharate and Amphetamine Aspartate and Dextroamphetamine Sulfate and Amphetamine ... Dextroamphetamine Saccharate and Amphetamine Aspartate and Dextroamphetamine Sulfate and Amphetamine ... Dextroamphetamine Saccharate and Amphetamine Aspartate and Dextroamphetamine Sulfate and Amphetamine …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …

Nystatin

Nystatin is a polyene antifungal drug that has broad-spectrum fungicidal and fungistatic activity against a number of yeasts and fungi, most notably Candida species. It is one of the most effective antifungal agents synthesized by bacteria, in this case a strain of Streptomyces noursei, and is closely related to amphotericin...
Approved
Vet approved
Matched Description: … a number of yeasts and fungi, most notably _Candida_ species. ... Nystatin is a polyene antifungal drug that has broad-spectrum fungicidal and fungistatic activity against ... antifungal agents synthesized by bacteria, in this case a strain of _Streptomyces noursei_,[L10776] and …
Matched Mixtures name: … Nystatin and Triamcinolone ... Nystatin and Triamcinolone ... Nystatin and Triamcinolone …
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Brompheniramine

Histamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria.
Approved
Matched Description: … Histamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria. …
Matched Mixtures name: … Up and Up Childrens Cold and Cough ... Dimetapp Cold and Cough and Nighttime Cold and Congestion ... Daytime Cold and Cough and NightTime Cold and Congestion Childrens …

Etravirine

Etravirine is an antiretroviral agent more specifically classified as a Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI). Etraverine is used clinically for the treatment of human immunodeficiency virus type 1 (HIV-1) infection. On January 18, 2007, the FDA granted accelerated approved for the use of etravirine 100mg tablets in the treatment of...
Approved
Matched Description: … consequently blocks DNA-dependent and RNA-dependent polymerase activity. ... effects of use include mild to moderate rash within the first 6 weeks of therapy, nausea, diarrhea and ... direct inhibition of the reverse transcriptase enzyme of human immunodeficiency virus type 1 (HIV-1), and …

Sulfacetamide

An anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.
Approved
Matched Description: … An anti-infective agent that is used topically to treat skin infections and orally for urinary tract …
Matched Mixtures name: … Sodium Sulfacetamide and Sulfur 10 Percent and 5 Percent Cleanser ... Sodium Sulfacetamide and Sulfur 10 Percent and 2 Percent Cleanser ... SODIUM SULFACETAMIDE and SULFUR …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Polymyxin B

Polymyxin B was discovered in the 1940s . They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes . Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic[A176426,FDA Label]. All gram-positive bacteria, fungi, and the gram-negative cocci,...
Approved
Vet approved
Matched Description: … Polymyxin B has a narrow therapeutic index and so its use is limited and unlikely to be used first line ... All gram-positive bacteria, fungi, and the gram-negative cocci, are resistant[A176426]. ... Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic …
Matched Mixtures name: … Neomycin and Polymyxin B Sulfates and Bacitracin Zinc ... Neomycin and Polymyxin B Sulfates and Dexamethasone ... Neomycin and Polymyxin B Sulfates and Hydrocortisone …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Ophthalmological and Otological Preparations …

Tocofersolan

D-Alpha-tocopheryl polyethylene glycol 1000 succinate (Tocofersolan, Vedrop), has been developed in Europe as an orally bioavailable source of vitamin E in children suffering from cholestasis . Cholestasis is the reduction or stoppage of bile flow, either to impaired secretion by hepatocytes (liver cells) or obstruction , . Tocofersolan is a...
Approved
Matched Description: … Tocofersolan is a polyethylene glycol derivative of α-tocopherol and synthetic water-soluble version ... capable of demonstrating antioxidant effects that make it a popular component to include in cosmetics and …
Matched Categories: … Alimentary Tract and Metabolism …

Bisoprolol

Bisoprolol is a cardioselective β1-adrenergic blocking agent used to treat high blood pressure.[A180472,L7219] It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive drugs. Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor...
Approved
Matched Iupac: … 1-[(propan-2-yl)amino]-3-(4-{[2-(propan-2-yloxy)ethoxy]methyl}phenoxy)propan-2-ol …
Matched Description: … alternative to non-selective β-blocker drugs in the treatment of hypertension such as [Carvedilol] and ... A180472] Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor selectivity and ... It may be used alone or in combination with other drugs to manage hypertension[L7219] and can be useful …
Matched Mixtures name: … Bisoprolol Fumarate and Hydrochlorothiazide ... Bisoprolol Fumarate and Hydrochlorothiazide ... Bisoprolol Fumarate and Hydrochlorothiazide …
Matched Categories: … ramipril and bisoprolol ... bisoprolol and thiazides ... bisoprolol and amlodipine ... perindopril and bisoprolol ... Beta Blocking Agents and Thiazides …

Ipratropium

Ipratropium is a quaternary ammonium derivative of atropine that acts as an anticholinergic agent. It is commonly administered through inhalation which allows producing a local effect without presenting a significant systemic absorption. Ipratropium as a therapeutic agent was developed by Boehringer Ingelheim and its first monotherapy product was FDA approved...
Approved
Experimental
Matched Iupac: … (1R,3R,5S)-3-[(3-hydroxy-2-phenylpropanoyl)oxy]-8-methyl-8-(propan-2-yl)-8-azabicyclo[3.2.1]octan-8-ium …
Matched Description: … product was FDA approved in 1986, while the combination product of ipratropium and [albuterol] was approved ... [A176957] Ipratropium as a therapeutic agent was developed by Boehringer Ingelheim and its first monotherapy …
Matched Mixtures name: … Ipratropium Bromide and Albuterol Sulfate ... Ipratropium Bromide and Albuterol Sulfate ... Ipratropium Bromide and Albuterol Sulfate …
Matched Categories: … fenoterol and ipratropium bromide ... salbutamol and ipratropium bromide …

Estriol

A hydroxylated metabolite of estradiol or estrone that has a hydroxyl group at C3-beta, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen. During pregnancy, large amount of estriol is produced by the placenta. Isomers with inversion of the hydroxyl group or groups are called epiestriol. Though estriol is...
Approved
Investigational
Vet approved
Matched Iupac: … (1R,2R,3aS,3bR,9bS,11aS)-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene …
Matched Description: … It has also been approved and marketed throughout Europe and Asia for approximately 40 years for the ... A hydroxylated metabolite of estradiol or estrone that has a hydroxyl group at C3-beta, 16-alpha, and …
Matched Categories: … Genito Urinary System and Sex Hormones ... Natural and Semisynthetic Estrogens, Plain ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Hydrocortisone probutate

Approved
Vet approved
Matched Categories: … Hydrocortisone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Albuterol

Salbutamol (Albuterol [USAN]) is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. Salbutamol is formulated as a...
Approved
Vet approved
Matched Description: … Salbutamol is formulated as a racemic mixture of the R- and S-isomers. ... USAN]) is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and ... The R-isomer has 150 times greater affinity for the beta2-receptor than the S-isomer and the S-isomer …
Matched Mixtures name: … Ipratropium Bromide and Albuterol Sulfate ... Ipratropium Bromide and Albuterol Sulfate ... Ipratropium Bromide and Albuterol Sulfate …
Matched Categories: … salbutamol and budesonide ... salbutamol and beclometasone ... salbutamol and sodium cromoglicate ... salbutamol and ipratropium bromide …

Atorvastatin

Atorvastatin (Lipitor®), is a lipid-lowering drug included in the statin class of medications. By inhibiting the endogenous production of cholesterol in the liver, statins lower abnormal cholesterol and lipid levels, and ultimately reduce the risk of cardiovascular disease. More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,...
Approved
Matched Description: … Bruce Roth and approved by the FDA in 1996. ... lipid levels, and ultimately reduce the risk of cardiovascular disease. ... inhibiting the endogenous production of cholesterol in the liver, statins lower abnormal cholesterol and …
Matched Mixtures name: … Amlodipine and atorvastatin ... Amlodipine and atorvastatin ... Amlodipine and atorvastatin …
Matched Categories: … atorvastatin and ezetimibe ... atorvastatin and amlodipine ... atorvastatin and perindopril ... atorvastatin, amlodipine and ramipril ... atorvastatin and acetylsalicylic acid …

Dipyridamole

A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
Approved
Matched Description: … A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular …
Matched Mixtures name: … Aspirin and Dipyridamole ... Aspirin and Dipyridamole ... Aspirin and Dipyridamole …
Matched Categories: … Blood and Blood Forming Organs …
Displaying drugs 251 - 275 of 15153 in total