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Displaying drugs 2751 - 2775 of 9510 in total

Sufentanil

Sufentanil is an opioid analgesic that is used as an adjunct in anesthesia, in balanced anesthesia, and as a primary anesthetic agent. It is administered by the intravenous, epidural and sublingual routes. Also known as Dsuvia, the sublingual form is used for the management of acute pain in adults that...
Approved
Investigational
Matched Description: … Also known as _Dsuvia_, the sublingual form is used for the management of acute pain in adults that is ... severe to warrant the use of an opioid analgesic in certified medically supervised healthcare settings ... Consideration may be made in the future for the use of the sublingual form in the US military in cases …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Magnesium carbonate

Magnesium carbonate, also known as magnesite, is a common over the counter remedy for heartburn and upset stomach caused by overproduction of acid in the stomach [FDA Label].
Approved
Investigational
Matched Description: … magnesite, is a common over the counter remedy for heartburn and upset stomach caused by overproduction of …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …

Efavirenz

Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency virus (HIV) type 1. For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with...
Approved
Investigational
Matched Description: … Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as part of ... highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency virus (HIV ... Efavirenz is also used in combination with other antiretroviral agents as part of an expanded postexposure …
Matched Categories: … Inducers of Drug Clearance ... Metabolic Side Effects of Drugs and Substances ... Antivirals used in combination for the treatment of HIV infections …

Rifampin

Rifampin, also known as rifampicin, is a broad-spectrum antimicrobial that was first discovered in 1965 and clinically used in 1968. Rifampin is used to treat tuberculosis and works by inhibiting the microbial DNA-dependent RNA polymerase (RNAP).
Approved
Matched Categories: … Drugs for Treatment of Lepra ... Drugs for Treatment of Tuberculosis ... Metabolic Side Effects of Drugs and Substances …

Dosulepin

Dosulepin (INN, BAN) formerly known as dothiepin (USAN), is a tricyclic antidepressant with anxiolytic properties that is used in several European and South Asian countries, as well as Australia, South Africa, and New Zealand. It is not FDA-approved due to low therpeutic index and significant toxicity in overdose. Dosulepin inhibits...
Approved
Matched Description: … Dosulepsin is a thio derivative of [DB00321] with a similar efficacy to that of [DB00321], and also exhibits ... Dosulepin inhibits the reuptake of biogenic amines, increasing available neurotransmitter levels at the ... The use of dosulepsin is only recommended in patients who are intolerant or unresponsive to alternative …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Frovatriptan

Frovatriptan is a triptan drug developed by Vernalis for the treatment of migraine headaches, in particular those associated with menstruation. Frovatriptan causes vasoconstriction of arteries and veins that supply blood to the head.
Approved
Investigational
Matched Description: … Frovatriptan causes vasoconstriction of arteries and veins that supply blood to the head. ... Frovatriptan is a triptan drug developed by Vernalis for the treatment of migraine headaches, in particular …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Ergoloid mesylate

Ergoloid Mesylate is an equiproportional preparation of three different ergotamantriones: dihydroergocornine, dihydroergocristine, and dihydroergocryptine. All these components are produced by the fungus Claviceps purpurea and are all derivatives of the tetracyclic compound 6-methylergonovine. The derivatives of this fungus are identified to be about 350 different substances from which the components...
Approved
Matched Description: … components of the ergoloid mesylate mixture are composed of the dihydrogenated ergot alkaloid derivatives ... Ergoloid Mesylate is an equiproportional preparation of three different ergotamantriones: dihydroergocornine ... A32912] All these components are produced by the fungus _Claviceps purpurea_ and are all derivatives of …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Inotuzumab ozogamicin

Inotuzumab ozogamicin is an antibody-drug conjugate consisting of a humanized IgG4 kappa CD22-targeting monoclonal antibody covalently attached to calicheamicin derivative, N-acetyl-gamma-calicheamicin dimethylhydrazide. The antibody portion of the drug binds to CD22 receptors expressed on leukemic B cells and intracellularly releases N-acetyl-gamma-calicheamicin dimethylhydrazide, which produces cytotoxic effects. Inotuzumab ozogamicin was first...
Approved
Investigational
Matched Description: … Inotuzumab ozogamicin is an antibody-drug conjugate consisting of a humanized IgG4 kappa CD22-targeting ... Inotuzumab ozogamicin was first approved by the European Commission in June 2017 for the treatment of ... [A20352] The antibody portion of the drug binds to CD22 receptors expressed on leukemic B cells and intracellularly …
Matched Categories: … CD22 (Clusters of Differentiation 22) inhibitors …

Acetaminophen

Acetaminophen (paracetamol), also commonly known as Tylenol, is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO). It is also used for its antipyretic effects, helping to reduce fever. This drug was initially approved by the U.S. FDA...
Approved
Matched Description: … [L5783] Confusion about dosing of this drug may be caused by the availability of different formulas, ... strengths, and dosage instructions for children of different ages. ... FDA in 1951 and is available in a variety of forms including syrup form, regular tablets, effervescent …
Matched Mixtures name: … DOSITAN (R) TABLETAS ... Regular Strength Cold Medication(daytime R.) ... Hot Lemon Relief for Symptoms Of Cold and Flu …
Matched Products: … PRODOL®R JARABE ... Babies R Us Pain Relief ... Babies R Us Pain and Fever …

Levomefolic acid

Levomefolic acid (INN) is the metabolite of folic acid (Vitamin B9) and it is a predominant active form of folate found in foods and in the blood circulation, accounting for 98% of folates in human plasma . It is transported across the membranes including the blood-brain barrier into various tissues...
Approved
Investigational
Matched Description: … It is available commercially as a crystalline form of the calcium salt (Metafolin(R)), which has the ... of folate found in foods and in the blood circulation, accounting for 98% of folates in human plasma ... Levomefolic acid (INN) is the metabolite of folic acid (Vitamin B9) and it is a predominant active form …

Metronidazole

Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics. It is frequently used to treat gastrointestinal infections as well as trichomoniasis and giardiasis, and amebiasis which are parasitic infections.[A181036,A181039] Metronidazole has been used as an antibiotic for several decades , with added antiparasitic properties that set...
Approved
Matched Description: … Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics. ... properties that set it apart from many other antibacterial drugs, allowing it to treat a wide variety of ... available in capsule form, tablet form, and topical form, and suppository preparations for the treatment of …
Matched Mixtures name: … MIKIUM(R) OVULOS …
Matched Categories: … combinations of imidazole derivatives …
Matched Products: … AMEFAR(R) TABLETA VAGINAL500 MG …

Thiamine

Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. Thiamine plays...
Approved
Investigational
Nutraceutical
Vet approved
Matched Description: … a key role in intracellular glucose metabolism and it is thought that thiamine inhibits the effect of ... Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of ... It is essential for normal growth and development and helps to maintain proper functioning of the heart …
Matched Mixtures name: … MIOBION(R) 1000 JERINGA PRELLENADA ... Harvest Of Values All B Complex Tab ... Herbs of Gold B Complex Plus Softgel …

Prilocaine

A local anesthetic that is similar pharmacologically to lidocaine. Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)
Approved
Matched Mixtures name: … R-LATE % 15 + % 5 DERİ SPREYİ, ÇÖZELTİ, 50 ML ... R-LATE % 15 + % 5 DERİ SPREYİ, ÇÖZELTİ, 6.5 ML …

Rolapitant

Rolapitant is a potent, highly selective, long-acting Neurokinin-1 (NK-1) receptor antagonist approved for the prevention of delayed chemotherapy-induced nausea and vomiting (CINV) in adults. Delayed-phase CINV typically occurs >24 hours after chemotherapy treatment and is principally mediated by Neurokinin-1 and its ligand Substance P, which is released in the gut...
Approved
Investigational
Matched Description: … , highly selective, long-acting Neurokinin-1 (NK-1) receptor antagonist approved for the prevention of ... Unlike other available NK-1 receptor antagonists, rolapitant is not an inhibitor of Cytochrome P450 enzyme …

Sulfisoxazole

A short-acting sulfonamide antibacterial with activity against a wide range of gram- negative and gram-positive organisms.
Approved
Vet approved
Matched Description: … A short-acting sulfonamide antibacterial with activity against a wide range of gram- negative and gram-positive …
Matched Categories: … combinations of sulfonamides …

Chlorthalidone

Chlorthalidone is a thiazide-like diuretic used for the treatment of hypertension and for management of edema caused by conditions such as heart failure or renal impairment. Chlorthalidone improves blood pressure and swelling by preventing water absorption from the kidneys through inhibition of the Na+/Cl− symporter in the distal convoluted tubule...
Approved
Matched Description: … of edema caused by conditions such as heart failure or renal impairment. ... Chlorthalidone is a thiazide-like diuretic used for the treatment of hypertension and for management ... improves blood pressure and swelling by preventing water absorption from the kidneys through inhibition of …
Matched Categories: … combinations of sulfonamides …

Stavudine

A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.
Approved
Investigational
Matched Categories: … Antivirals used in combination for the treatment of HIV infections …

Naltrexone

Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of naloxone. It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction. The FDA has approved naltrexone for the treatment of alcohol dependence.
Approved
Investigational
Vet approved
Matched Description: … Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of naloxone. ... The FDA has approved naltrexone for the treatment of alcohol dependence. ... effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Levacetylmethadol

Levacetylmethadol is a narcotic analgesic with a long onset and duration of action. It is used mainly in the treatment of narcotic dependence. Levacetylmethadol was withdrawn from use in the European Union due to its high risk of QT interval prolongation. The production of levacetylmethadol in the US has ceased...
Approved
Investigational
Withdrawn
Matched Description: … It is used mainly in the treatment of narcotic dependence. ... Levacetylmethadol is a narcotic analgesic with a long onset and duration of action. ... The production of levacetylmethadol in the US has ceased as well.[L44052,T862] …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Dihydrocodeine

Dihydrocodeine is an opioid analgesic used as an alternative or adjunct to codeine to treat moderate to severe pain, severe dyspnea, and cough. It is semi-synthetic, and was developed in Germany in 1908 during an international search to find a more effective antitussive agent to help reduce the spread of...
Approved
Illicit
Matched Description: … during an international search to find a more effective antitussive agent to help reduce the spread of …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Butriptyline

Butriptyline is a tricyclic antidepressant which has been used in Europe since 1974. It is the isobutyl side chain homologue of amitriptyline.
Approved
Withdrawn
Matched Description: … It is the isobutyl side chain homologue of amitriptyline. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Dasabuvir

Dasabuvir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Matched Description: … reduced liver-related damage, improved quality of life, reduced incidence of Hepatocellular Carcinoma ... Dasabuvir is a direct acting antiviral medication used as part of combination therapy to treat chronic ... nine distinct genotypes, with genotype 1 being the most common in the United States, and affecting 72% of …
Matched Categories: … Antivirals for treatment of HCV infections …

Amoxicillin

Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972. Amoxicillin has similar activity to penicillin and ampicillin, but leads to higher serum concentrations than ampicillin. Amoxicillin was granted FDA approval on 18 January 1974.
Approved
Vet approved
Matched Mixtures name: … AMOXICILLIN R C875MG/125MG ... AMOXICILLIN R C875MG/125MG …
Matched Categories: … combinations of penicillins …
Matched Products: … โคอะมอกซ์ (R) 500 ... AMOXICILINA 500 MG CAPSULAS CALOX(R) ... AMOXICILINA250 MG / 5 ML POLVO PARA RECONSTITUIR A SUSPENSION ORAL CALOX(R) …

Rucaparib

Rucaparib is an anticancer drug and poly (ADP-ribose) polymerase (PARP) inhibitor. PARP is an enzyme that plays an essential role in DNA repair. Rucaparib is proposed to work in several PARP-dependent and PARP-independent mechanisms of action; however, it causes a unique effect of synthetic lethality. By targeting the genetically-mutated cancer...
Approved
Investigational
Matched Description: … ; however, it causes a unique effect of synthetic lethality. ... [A18745] Rucaparib is proposed to work in several PARP-dependent and PARP-independent mechanisms of action …

Rilpivirine

Rilpivirine is non-nucleoside reverse transcriptase inhibitor (NNRTI) which is used for the treatment of HIV-1 infections in treatment-naive patients. It is a diarylpyrimidine derivative. The internal conformational flexibility of rilpivirine and the plasticity of it interacting binding site gives it a very high potency and reduces the chance of resistance...
Approved
Matched Description: … [A31329] The internal conformational flexibility of rilpivirine and the plasticity of it interacting ... Rilpivirine is non-nucleoside reverse transcriptase inhibitor (NNRTI) which is used for the treatment of ... binding site gives it a very high potency and reduces the chance of resistance compared to other NNRTI's …
Matched Categories: … Antivirals used in combination for the treatment of HIV infections …
Displaying drugs 2751 - 2775 of 9510 in total