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Did you mean bitopertin of rp 493838 of r 18 of ビトペルチン?
Displaying drugs 2826 - 2850 of 9610 in total

Thioridazine

A phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the control of severely disturbed or agitated behavior. It has little antiemetic activity. Thioridazine has a higher incidence of antimuscarinic effects, but a lower incidence of extrapyramidal symptoms, than chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed,...
Approved
Withdrawn
Matched Description: … Thioridazine has a higher incidence of antimuscarinic effects, but a lower incidence of extrapyramidal ... control of severely disturbed or agitated behavior. ... A phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Glecaprevir

Glecaprevir is a direct acting antiviral agent and Hepatitis C virus (HCV) NS3/4A protease inhibitor that targets the the viral RNA replication. In combination with DB13878, glecaprevir is a useful therapy for patients who experienced therapeutic failure from other NS3/4A protease inhibitors. It demonstrates a high genetic barrier against resistance...
Approved
Investigational
Matched Description: … treatment, of ≥93% across genotypes 1a, 2a, 3a, 4, 5 and 6 [FDA Label]. ... It demonstrates a high genetic barrier against resistance mutations of the virus. ... The combinations of amino acid substitutions at NS3 position Y65H and D/Q168 also results in greater …
Matched Categories: … Antivirals for treatment of HCV infections …

Paliperidone

Paliperidone is the primary active metabolite of risperidone. The mechanism of action is unknown but it is likely to act via a similar pathway to risperidone. It has been proposed that the drug's therapeutic activity in schizophrenia is mediated through a combination of central dopamine Type 2 (D2) and serotonin...
Approved
Matched Description: … the other effects of the drug. ... Paliperidone is the primary active metabolite of risperidone. ... The mechanism of action is unknown but it is likely to act via a similar pathway to risperidone. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Dimazole

Dimazole (diamthazole) is an antifungal. It was withdrawn in Franch in 1972 due to neuropsychiatric reactions.
Approved
Withdrawn

Rubidium

Approved
Investigational

Cisapride

In many countries (including Canada) cisapride has been either withdrawn or has had its indications limited due to reports about long QT syndrome due to cisapride, which predisposes to arrhythmias. The FDA issued a warning letter regarding this risk to health care professionals and patients.
Approved
Investigational
Withdrawn
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Phenelzine

Phenelzine, with the formula β-phenylethylhydrazine, is a monoamine oxidase inhibiting antidepressant that is effective in the treatment of panic disorder and social anxiety disorder. It was developed by Parke Davis and originally FDA approved on June 9th, 1961. It is currently approved under prescription by the name of Nardil.
Approved
Matched Description: … It is currently approved under prescription by the name of Nardil. ... β-phenylethylhydrazine, is a monoamine oxidase inhibiting antidepressant that is effective in the treatment of …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Dihydroergotamine

A 9,10alpha-dihydro derivative of ergotamine. Dihydroergotamine is used as an abortive therapy for migraines. Its use has largely been supplanted by triptans in current therapy due to the class's greater selectivity and more favourable side effect profile. Recent improvements have been made in the design of intranasal delivery devices allowing...
Approved
Investigational
Matched Description: … 3-fold in Cmax and 4-fold in AUC despite the solution formulated at 75% of the strength of the existing ... A 9,10alpha-dihydro derivative of [ergotamine]. ... delivery of dihydroergotamine solution to the vasculature-rich upper nasal cavity. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Trimethoprim

Trimethoprim is an antifolate antibacterial agent that inhibits bacterial dihydrofolate reductase (DHFR), a critical enzyme that catalyzes the formation of tetrahydrofolic acid (THF) - in doing so, it prevents the synthesis of bacterial DNA and ultimately continued bacterial survival. Trimethoprim is often used in combination with sulfamethoxazole due to their...
Approved
Vet approved
Matched Description: … that inhibits bacterial dihydrofolate reductase (DHFR), a critical enzyme that catalyzes the formation of ... tetrahydrofolic acid (THF) - in doing so, it prevents the synthesis of bacterial DNA and ultimately ... complementary and synergistic mechanisms but may be used as a monotherapy in the treatment and/or prophylaxis of …
Matched Mixtures name: … SOLASTEM(R) TABLETAS ... MEDIPRIM F (R) TABLETA ... MEDIPRIM F (R) TABLETA …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …

Rifabutin

A broad-spectrum antibiotic that is being used as prophylaxis against disseminated Mycobacterium avium complex infection in HIV-positive patients.
Approved
Investigational
Matched Categories: … Drugs for Treatment of Tuberculosis …

Primidone

Primidone is an anticonvulsant used to treat essential tremor as well as grand mal, psychomotor, and focal epileptic seizures. Primidone was developed by J Yule Bogue and H C Carrington in 1949. Primidone was granted FDA Approval on 8 March 1954.
Approved
Vet approved
Matched Categories: … combinations of barbiturates …

Clonostachys rosea f. rosea

Clonostachys rosea f. rosea allergenic extract is used in allergenic testing.
Approved

D-glucose

Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through...
Approved
Investigational
Vet approved
Matched Description: … Its aldohexose stereoisomer, dextrose or D-glucose, is the most commonly occurring isomer of glucose ... It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis ... [T28] The unspecified form of glucose is commonly supplied as an injection for nutritional supplementation …
Matched Mixtures name: … Reveos Select CPD/AS-5 Red Cell Preservative For Collection Of Blood ... IMUFLEX WB-RP Blood Bag System with Integral Whole Blood Leukocyte Reduction Filter (Removing Platelets ... IMUFLEX WB-RP Blood Bag System with Integral Whole Blood Leukocyte Reduction Filter (Removing Platelets …

Benzoyl peroxide

Benzoyl peroxide is a commonly used drug in topical treatments for acne.[L33249,L33264,L33269,L33299,L33314] It has been formulated as products with either a single active ingredient,[L33249,L33299] or with erythromycin, clindamycin, or adapalene. After administration, the peroxide bond is cleaved, allowing benzoyloxy radicals to nonspecifically interact with proteins.[A18903,A233859] This treatment decreases keratin and...
Approved
Matched Description: … A233859] This treatment decreases keratin and sebum around follicles, as well as increasing turnover of …
Matched Mixtures name: … R+f Paired Regimen for Wrinkles + Occasional Acne …
Matched Products: … BENZAC(R) AC 2 1/2 ... NeoBenz(R) Micro Benzoyl Peroxide Wash, 7% …

Rofecoxib

Rofecoxib is used for the treatment of osteoarthritis, rheumatoid arthritis, acute pain in adults, and primary dysmenorrhea, as well as acute treatment of migraine attacks with or without auras. Rofecoxib is a solid. This compound belongs to the stilbenes. These are organic compounds containing a 1,2-diphenylethylene moiety. Stilbenes (C6-C2-C6 )...
Approved
Investigational
Withdrawn
Matched Description: … doses of 125, 25, and 50 mg is approximately 93%. ... The introduction of one or more hydroxyl groups to a phenyl ring lead to stilbenoids. ... primary dysmenorrhea, as well as acute treatment of migraine attacks with or without auras. …

Rosoxacin

Rosoxacin is a quinolone derivative antibiotic for the treatment of bacterial infection of respiratory tract, urinary tract, GI, CNS and immuno compromised patients. Rosoxacin is known to be effective against penicillin resistant strains and is a single dose orally administered drug, which avoids all complications of parenteral administration seen with...
Approved
Investigational
Matched Description: … Rosoxacin is a quinolone derivative antibiotic for the treatment of bacterial infection of respiratory ... penicillin resistant strains and is a single dose orally administered drug, which avoids all complications of …

Red pepper

Red pepper allergenic extract is used in allergenic testing.
Approved

Tobramycin

Aminoglycosides, many of which are derived directly from Streptomyces spp., are concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive and Gram-negative organisms. Inhaled tobramycin is notable for its use in treating chronic Pseudomonas aeruginosa infections in cystic fibrosis patients, as P. aeruginosa is notoriously inherently resistant to...
Approved
Investigational
Matched Description: … Aminoglycosides, many of which are derived directly from _Streptomyces_ spp., are concentration-dependent ... L32739] However, tobramycin can also be administered intravenously and topically to treat a variety of ... bactericidal antibiotics with a broad spectrum of activity against Gram-positive and Gram-negative organisms …
Matched Mixtures name: … GOTABIOTIC(R)F OFTALMICO …

Losartan

Losartan is an angiotensin II receptor blocker (ARB) used to treat hypertension. Angiotensin-converting enzyme (ACE) inhibitors are used for a similar indication but are associated with a cough. When patients with ACE inhibitor associated coughs are switched to ARBs like losartan, they have an incidence of cough similar to placebo...
Approved
Matched Description: … patients with ACE inhibitor associated coughs are switched to ARBs like losartan, they have an incidence of ... [L7423] Losartan is available as losartan potassium oral tablets as well as a combination tablet of losartan …
Matched Products: … ATRELAN (R) 50MG/TABLETAS …

Salicylic acid

A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions. Its salts, the salicylates, are used as analgesics.
Approved
Investigational
Vet approved
Matched Description: … A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically …
Matched Products: … R-044 Blemish Fix ... Fruit of the Earth Acne Wash …

Chondroitin sulfate

Chondroitin sulfate is a glycosaminoglycan considered as a symptomatic slow-acting drug for osteoarthritis (SYSADOA). The SYSADOA status suggested a pain relief and increased joint mobility after a relative long regular administration, as well as a long-lasting effect after the end of the treatment. Chondroitin sulfate is composed of alternating 1,3-N-acetyl-β-d-galactosamine...
Approved
Investigational
Nutraceutical
Matched Description: … Chondroitin sulfate is composed of alternating 1,3-N-acetyl-β-d-galactosamine and 1,4-β-d-glucuronic ... mobility after a relative long regular administration, as well as a long-lasting effect after the end of ... acid units which bear 4-O- and/or 6-O-sulfations at the N-acetylgalactosamine units disposed of in specific …
Matched Mixtures name: … ARTROFORT(R) COMPLEX …

Rimexolone

Rimexolone is a 1% eye drop solution is a glucocorticoid steroid. It is used to treat inflammation in the eye. It is marketed as Vexol.
Approved

Roxadustat

Roxadustat is a first-in-class hypoxia-inducible factor prolyl hydroxylase inhibitor used to treat anemia associated with chronic kidney disease. It works by reducing the breakdown of the hypoxia-inducible factor (HIF), which is a transcription factor that stimulates red blood cell production in response to low oxygen levels. Roxadustat was first approved...
Approved
Investigational
Matched Description: … It works by reducing the breakdown of the hypoxia-inducible factor (HIF), which is a transcription factor …

Romidepsin

Romidepsin is a selective inhibitor of histone deacetylase, approved in the US in 2009 for the treatment of cutaneous T-cell lymphoma (CTCL) in patients who have received at least one prior systemic therapy.
Approved
Investigational
Matched Description: … Romidepsin is a selective inhibitor of histone deacetylase, approved in the US in 2009 for the treatment ... of cutaneous T-cell lymphoma (CTCL) in patients who have received at least one prior systemic therapy …

Red currant

Red currant allergenic extract is used in allergenic testing.
Approved
Displaying drugs 2826 - 2850 of 9610 in total