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Displaying drugs 2901 - 2925 of 9629 in total
Bromazepam
One of the benzodiazepines that is used in the treatment of anxiety disorders. It is a Schedule IV drug in the U.S. and Canada and under the Convention on Psychotropic Substances. It is a intermediate-acting benzodiazepine.
Approved
Illicit
Investigational
Matched Description: … One of the benzodiazepines that is used in the treatment of anxiety disorders. …
Eleuthero
Eleuthero is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Respiratory syncytial virus vaccine, adjuvanted
Arexvy (respiratory syncytial virus vaccine, adjuvanted) is an adjuvanted vaccine developed by GlaxoSmithKline Biologicals. It comprises lyophilized recombinant respiratory syncytial virus glycoprotein F (RSVPreF3) stabilized in pre-fusion conformation as the antigen component, which is reconstituted at the time of use with the accompanying vial of AS01E adjuvant as the adjuvant...
Approved
Matched Description: … use with the accompanying vial of AS01E adjuvant as the adjuvant suspension component. ... stabilized in pre-fusion conformation as the antigen component, which is reconstituted at the time of …
Lubiprostone
Lubiprostone is a medication used in the management of idiopathic chronic constipation. A prostaglandin E1 derivative, lubiprostone is a bicyclic fatty acid that activates ClC-2 chloride channels located on the apical side of the gastrointestinal epithelial cells. Activation of these channels promotes the secretion of a chloride-rich fluid that soften...
Approved
Investigational
Matched Description: … Activation of these channels promotes the secretion of a chloride-rich fluid that soften the stool, increase ... Lubiprostone is a medication used in the management of idiopathic chronic constipation. ... lubiprostone is a bicyclic fatty acid that activates ClC-2 chloride channels located on the apical side of …
Perhexiline
Perhexiline is a coronary vasodilator used especially for angina of effort. It may cause neuropathy and hepatitis.
Approved
Investigational
Matched Description: … Perhexiline is a coronary vasodilator used especially for angina of effort. …
Fingolimod
Multiple sclerosis, or MS, is a devastating inflammatory disease that often progresses and causes severe neurological, physical, and cognitive effects. Fingolimod is a sphingosine 1-phosphate receptor modulator for the treatment of relapsing-remitting multiple sclerosis. It was developed by Novartis and initially approved by the FDA in 2010. Fingolimod was also...
Approved
Investigational
Matched Description: … [L12651] Fingolimod was also studied for the treatment of COVID-19, the disease caused by infection with ... [A176474] Fingolimod is a sphingosine 1-phosphate receptor modulator for the treatment of relapsing-remitting …
Telotristat ethyl
Telotristat ethyl is a prodrug of telotristat that was approved by the FDA in March 2017 as Xermelo. It was previously referred to as telotristat etiprate, the hippurate salt form; however, the FDA recommends the use of the name of the neutral form rather than that of the salt.[A252937, A252942]...
Approved
Investigational
Matched Description: … the name of the neutral form rather than that of the salt. ... over the course of the disease. ... [L43367] Overexposure to serotonin can cause severe diarrhea, one of the main clinical symptoms of carcinoid …
Cephalosporium roseum
Cephalosporium roseum allergenic extract is used in allergenic testing.
Approved
Vorinostat
Vorinostat (rINN) or suberoylanilide hydroxamic acid (SAHA), is a drug currently under investigation for the treatment of cutaneous T cell lymphoma (CTCL), a type of skin cancer, to be used when the disease persists, gets worse, or comes back during or after treatment with other medicines. It is the first...
Approved
Investigational
Matched Description: … It is the first in a new class of agents known as histone deacetylase inhibitors. ... Further brain tumor trials are planned using combinations of vorinostat with other drugs. ... or suberoylanilide hydroxamic acid (SAHA), is a drug currently under investigation for the treatment of …
Choline salicylate
Choline salicylate is an anti-inflammatory pain reliever agent that is related to aspirin. It is used to decrease swelling and to treat mild-moderate pain. It is used to treat arthritis in both children and adults. This medicine can also be used for fever .
Choline Salicylate is the choline salt...
Approved
Nutraceutical
Matched Description: … The UK government has regulated its use, due to toxicity in those under 16 years of age. ... Choline salicylate is effective in the treatment of gout, rheumatic fever, rheumatoid arthritis and muscle ... Choline Salicylate is the choline salt of salicylic acid, used as an analgesic, antipyretic and antirheumatic …
Pravastatin
Pravastatin is the 6-alpha-hydroxy acid form of mevastatin. Pravastatin was firstly approved in 1991 becoming the second available statin in the United States. It was the first statin administered as the active form and not as a prodrug. This drug was developed by Sankyo Co. Ltd.; however, the first approved...
Approved
Matched Description: … Pravastatin is the 6-alpha-hydroxy acid form of [mevastatin]. ... The manufacturing process is followed by the hydrolysis of the lactone group and the biological hydroxylation …
Mifepristone
Mifepristone is a progestational and glucocorticoid hormone antagonist. Its inhibition of progesterone induces bleeding during the luteal phase and in early pregnancy by releasing endogenous prostaglandins from the endometrium or decidua. As a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients with nonpituitary cushing syndrome....
Approved
Investigational
Matched Description: … Its inhibition of progesterone induces bleeding during the luteal phase and in early pregnancy by releasing ... The two marketed forms of mifepristone are Mifeprex® (mifepristone 200mg) and Korlym™ (mifepristone 300mg …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Bromhexine
Bromhexine is mucolytic agent used for a variety of respiratory conditions associated with increased mucus secretion. It is derived from the Adhatoda vasica plant and aids in the clearance of excess mucus, improving breathing and reducing cough. It was introduced into the market in 1963, and is widely available as...
Approved
Matched Description: … Bromhexine is mucolytic agent used for a variety of respiratory conditions associated with increased ... It is derived from the Adhatoda vasica plant and aids in the clearance of excess mucus, improving breathing ... bromhexine and its metabolite [ambroxol] have garnered interest for the potential prevention and treatment of …
Choline C-11
Choline C 11 Injection is a radioactive diagnostic agent for positron emission tomography (PET) imaging of pat ients with suspected prostate cancer recurrence and non-informative bone scintigraphy, computerized tomography (CT) or magnetic resonance imaging.
Approved
Matched Description: … Choline C 11 Injection is a radioactive diagnostic agent for positron emission tomography (PET) imaging of …
Linzagolix
Linzagolix is a non-peptide, selective antagonist of the gonadotropin-releasing hormone (GnRH) receptor. It has been studied for the treatment of estrogen-dependent conditions such as uterine fibroids and endometriosis.[A253642,A253647] It is similar to other GnRH receptor antagonists like cetrorelix, relugolix, and elagolix.
Uterine fibroids occur in >70% of women of reproductive...
Approved
Matched Description: … Uterine fibroids occur in >70% of women of reproductive age, and when symptomatic are associated with ... Linzagolix is a non-peptide, selective antagonist of the gonadotropin-releasing hormone (GnRH) receptor ... [A253667]
Linzagolix was approved for use in the European Union in June 2022 for the management of …
Dalbavancin
Dalbavancin is a second-generation lipoglycopeptide antibiotic that was designed to improve on the natural glycopeptides currently available, such as vancomycin and teicoplanin [A4072, A4073]. Modifications from these older glycoprotein classes facilitated a similar mechanism of action for dalbavancin but with increased activity and once-weekly dosing [FDA Label, F2356, A4072, A4073]....
Approved
Investigational
Matched Description: … Its use is indicated for the treatment of acute bacterial skin and skin structure infections (ABSSSI) ... Modifications from these older glycoprotein classes facilitated a similar mechanism of action for dalbavancin ... acts by interfering with bacterial cell wall synthesis by binding to the D-alanyl-D-alanine terminus of …
Adenosine
The structure of adenosine was first described in 1931, though the vasodilating effects were not described in literature until the 1940s. Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy, though it is rarely used in this indication, having largely been replaced by dipyridamole and [regadenson].[A229833,A229838] Adenosine...
Approved
Investigational
Matched Description: … The structure of adenosine was first described in 1931,[A229823] though the vasodilating effects were ... [A229833,A229838] Adenosine is also indicated in the treatment of supraventricular tachycardia. …
Matched Mixtures name: … Plalab Placenta R-20 …
Matched Mixtures name: … Plalab Placenta R-20 …
Conivaptan
Conivaptan is a non-peptide inhibitor of antidiuretic hormone (vasopressin). It was approved in 2004 for hyponatremia (low blood sodium levels) caused by syndrome of inappropriate antidiuretic hormone (SIADH). Conivaptan inhibits both isotypes of the vasopressin receptor (V1a and V2).
Approved
Investigational
Matched Description: … Conivaptan is a non-peptide inhibitor of antidiuretic hormone (vasopressin). ... Conivaptan inhibits both isotypes of the vasopressin receptor (V1a and V2). ... It was approved in 2004 for hyponatremia (low blood sodium levels) caused by syndrome of inappropriate …
Edoxudine
Edoxudine is a deoxythymidine analog with activity against herpes simplex virus. It is a potent and selective inhibitor of herpes simplex virus type 1 and 2. The obtained product is an antiviral ointment. The activity of edoxudine against herpes simplex virus was first recognized in 1967. It was later recognized...
Approved
Investigational
Withdrawn
Matched Description: … It is a potent and selective inhibitor of herpes simplex virus type 1 and 2. ... [L2407] The activity of edoxudine against herpes simplex virus was first recognized in 1967. ... It was later recognized to be effective in vivo in a preclinical model of keratitis caused by herpes …
Thimerosal
Thiomersal (INN), commonly known in the U.S. as thimerosal, is an organomercury compound. This compound is a well-established and widely used antiseptic and antifungal agent.
Developed in 1927, thimerosal has been and is still being used as a preservative in some cosmetics, topical pharmaceuticals, and biological drug products, which includes...
Approved
Insulin lispro
Insulin lispro is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the pancreas...
Approved
Matched Description: … high levels of insulin in a short period of time to mimic the release of endogenous insulin from the ... , with a goal of avoiding any periods of hypoglycemia. ... Insulin lispro is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type …
Sorafenib
Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated in tumour cell proliferation and tumour angiogenesis. First approved by the FDA and European Commission in 2007 for the treatment of hepatocellular carcinoma, sorafenib is also...
Approved
Investigational
Matched Description: … [A255852] First approved by the FDA and European Commission in 2007 for the treatment of hepatocellular …
Olodaterol
Olodaterol is a novel, long-acting beta2-adrenergic agonist (LABA) that exerts its pharmacological effect by binding and activating beta2-adrenergic receptors located primarily in the lungs. Beta2-adrenergic receptors are membrane-bound receptors that are normally activated by endogenous epinephrine whose signalling, via a downstream L-type calcium channel interaction, mediates smooth muscle relaxation and...
Approved
Matched Description: … of COPD or for the treatment of asthma. ... Elevation of these two molecules induces bronchodilation by relaxation of airway smooth muscles. ... (COPD) and the progressive airflow obstruction that is characteristic of it. …
Lorlatinib
Lorlatinib is a third-generation ALK tyrosine kinase inhibitor (TKI) for patients with ALK-positive metastatic non-small cell lung cancer which was first approved by the US FDA in November of 2018. It was subsequently approved by the EMA in 2019 for the treatment of select patients with previously treated advanced ALK-positive...
Approved
Investigational
Matched Description: … It was subsequently approved by the EMA in 2019 for the treatment of select patients with previously ... ALK-positive metastatic non-small cell lung cancer[L39905] which was first approved by the US FDA in November of …
Apixaban
Apixaban is an oral, direct, and highly selective factor Xa (FXa) inhibitor of both free and bound FXa, as well as prothrombinase, independent of antithrombin III for the prevention and treatment of thromboembolic diseases[Label,A6897]. It is marketed under the name Eliquis[Label,L6043]. Apixaban was approved by the FDA on December 28,...
Approved
Matched Description: … , as well as prothrombinase, independent of antithrombin III for the prevention and treatment of thromboembolic ... Apixaban is an oral, direct, and highly selective factor Xa (FXa) inhibitor of both free and bound FXa …
Displaying drugs 2901 - 2925 of 9629 in total