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Displaying drugs 2951 - 2975 of 15149 in total

Diltiazem

Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. Approved in 1982 by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug class. It works through various mechanisms of action, but it primarily works by inhibiting the calcium influx into cardiac and vascular smooth muscle...
Approved
Investigational
Matched Synonyms: … Acetic acid (2S,3S)-5-(2-dimethylamino-ethyl)-2-(4-methoxy-phenyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][ ... cis-5-[2-(dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(p-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one acetate ... -5-(2-(dimethylamino)ethyl)-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl acetate …
Matched Iupac: … 3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate …
Matched Description: … Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. ... under various brand names with Cardizem and Tiazac being the most common ones. ... various mechanisms of action, but it primarily works by inhibiting the calcium influx into cardiac and …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …

Valine

Valine is a branched-chain essential amino acid that has stimulant activity. It promotes muscle growth and tissue repair. It is a precursor in the penicillin biosynthetic pathway.
Approved
Nutraceutical
Matched Synonyms: … 2-Amino-3-methylbutyric acid ... (2S)-2-Amino-3-methylbutanoic acid ... L-(+)-alpha-Aminoisovaleric acid …
Matched Iupac: … (2S)-2-amino-3-methylbutanoic acid …
Matched Description: … It promotes muscle growth and tissue repair. ... Valine is a branched-chain essential amino acid that has stimulant activity. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Travasol Amino Acid Inj 8.5% …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Colistimethate

Colistimethate is an antibiotic that has been shown to have bactericidal activity against aerobic gram-negative microorganisms. Colistimethate is particularly indicated when the infection is caused by sensitive strains of Pseudomonas aeruginosa.
Approved
Vet approved
Matched Synonyms: … Colistin methanesulfonic acid ... Colistinmethanesulfonic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Sodium fluorophosphate

Sodium monofluorophosphate is used in OTC dental preparations to help protect against cavities.
Approved
Matched Synonyms: … Phosphorofluoridic acid, disodium salt …
Matched Mixtures name: … Chunzam Silk Amino Acid Tooth ... Mentadent Specialty Whitening Toothpaste and Polishing ... Hawaiian Airline EC with Colgate Toothbrush and Sun …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Schmidts MINT and BERRY KIDS TOOTH AND MOUTH ... Schmidts WATERMELON and STRAWBERRY KIDS TOOTH AND MOUTH ... Thomas and Friends …

Ketoprofen

Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.
Approved
Vet approved
Matched Synonyms: … 3-Benzoylhydratropic acid ... m-Benzoylhydratropic acid ... 2-(3-Benzoylphenyl)propionic acid …
Matched Iupac: … 2-(3-benzoylphenyl)propanoic acid …
Matched Description: … and antipyretic properties. ... Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic …
Matched Categories: … Arylpropionic acid NSAIDS ... Ketoprofen and isomer ... Amino Acids, Peptides, and Proteins ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain …

Cabazitaxel

Cabazitaxel is a taxoid synthesized from 10-deacetylbaccatin III, a compound isolated from the yew tree. As a second-generation semisynthetic microtubule inhibitor, cabazitaxel stabilizes microtubules and induces tumour cell death. Due to its low affinity for the P-glycoprotein (P-gp) efflux pump, cabazitaxel can more readily penetrate the blood–brain barrier compared to...
Approved
Matched Synonyms: … -TRIYL 4-ACETATE 2-BENZOATE 13-((2R,3S)-3-(((TERT-BUTOXY)CARBONYL)AMINO)-2-HYDROXY-3-PHENYLPROPANOATE …
Matched Description: … A260621] As a second-generation semisynthetic microtubule inhibitor, cabazitaxel stabilizes microtubules and ... [A260421] It was also approved by the EMA on March 17, 2011 [L47381] and Health Canada on December 17 ... cabazitaxel can more readily penetrate the blood–brain barrier compared to other taxanes like [paclitaxel] and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … JEVTANA 60mg CONCENTRATE AND SOLVENT FOR SOLUTION FOR INFUSION ... JEVTANA (CONCENTRATE AND SOLVENT FOR SOLUTION FOR INFUSION) ... Concentrate and Solvent for Solution for Infusion 60mg/1.5ml …

Nogapendekin alfa

Nogapendekin alfa is a human IL-15N72D variant. It is one of the active ingredients in Anktiva, a combination product also containing inbakicept, where a single inbakicept is complexed with two nogapendekin alfa components. This combination product was approved by the FDA on April 22, 2024, for the treatment of BCG-unresponsive...
Approved
Investigational
Matched Synonyms: … Fusion protein consisting of il-15n72d and il-15rasu/fc ... Human interleukin 15 (72-aspartic acid) (human il-15 n72>d isoform) …
Matched Description: … 75% of all bladder tumours, is commonly treated with transurethral resection of the bladder tumour and ... proliferation of natural killer cells and CD8+ memory T cells, which also synergistically enhance BCG ... Nogapendekin alfa, in combination with inbakicept, mimics the actions of IL-15, , stimulating the activation and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Bufexamac

Bufexamac is a non-steroidal anti-inflammatory drug (NSAID) under the market name Droxaryl, Malipuran, Paraderm and Parfenac. It is typically administered topically for the treatment of subacute and chronic eczema of the skin, including atopic eczema and other inflammatory dermatoses, as well as sunburn and other minor burns, and itching. It...
Approved
Withdrawn
Matched Synonyms: … Bufexamic acid ... 4-Butoxyphenylacetohydroxamic acid ... 2-(p-Butoxyphenyl)-acetohydroxamic acid …
Matched Description: … and itching. ... including atopic eczema and other inflammatory dermatoses, as well as sunburn and other minor burns, ... clinical efficacy and a high prevalence of contact sensitization [A32822]. …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …

Cyclophosphamide

Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the liver to form the active aldophosphamide. It has been used in the treatment of lymphoma and leukemia. Its side effect, alopecia, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects,...
Approved
Investigational
Matched Synonyms: … Anhydrous cyclophosphamide ... Cyclophosphamide anhydrous …
Matched Description: … It has been used in the treatment of lymphoma and leukemia. ... Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer. ... Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

L-Glutamine

A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from glutamic acid and ammonia. It is the principal carrier of nitrogen in the body and is an important energy source for many cells. An oral formulation of L-glutamine was approved...
Approved
Investigational
Nutraceutical
Matched Synonyms: … Glutamic acid amide ... Glutamic acid 5-amide ... L-glutamic acid γ-amide …
Matched Iupac: … (2S)-2-amino-4-carbamoylbutanoic acid …
Matched Description: … It is synthesized from glutamic acid and ammonia. ... A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes ... It is the principal carrier of nitrogen in the body and is an important energy source for many cells. …
Matched Categories: … Amino Acids and Derivatives ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …

Fosfomycin

Fosfomycin was discovered in 1969 by scientists at the Spanish Penicillin and Antibiotics Company and is produced by Streptomyces fradiae.[A229338,A230348] It may also be produced synthetically and is commercially available as the disodium salt for intravenous administration and as the calcium or trometamol salt for oral administration. In terms of...
Approved
Matched Synonyms: … (1R,2S)-epoxypropylphosphonic acid ... L-cis-1,2-epoxypropylphosphonic acid ... cis-(1R,2S)-epoxypropylphosphonic acid …
Matched Iupac: … [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid …
Matched Description: … group and an epoxide ring. ... Fosfomycin was discovered in 1969 by scientists at the Spanish Penicillin and Antibiotics Company and ... is active against both gram-positive and gram-negative bacteria. …

Probenecid

The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
Approved
Investigational
Matched Synonyms: … Probenecid acid ... p-(Dipropylsulfamoyl)benzoic acid ... 4-((Dipropylamino)sulfonyl)benzoic acid …
Matched Iupac: … 4-(dipropylsulfamoyl)benzoic acid …
Matched Description: … It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. ... Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal …
Matched Mixtures name: … Probenecid and Colchicine ... Probenecid and Colchicine ... Probenecid and Colchicine …
Matched Categories: … Preparations Increasing Uric Acid Excretion ... Preparations With No Effect on Uric Acid Metabolism ... colchicine and probenecid ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Ouabain

A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like digitalis. It is commonly used in cell biological studies as an inhibitor of the NA(+)-K(+)-exchanging ATPase.
Approved
Matched Synonyms: … Ouabain anhydrous …
Matched Description: … gratus and other plants of the Apocynaceae; used like digitalis. ... A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus …

alpha-Tocopherol succinate

Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the...
Approved
Nutraceutical
Vet approved
Matched Synonyms: … alpha-Tocopheryl acid succinate ... d-alpha-Tocopherol acid succinate ... Tocopheryl acid succinate,D-alpha …
Matched Iupac: … 2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-yl]oxy}butanoic acid …
Matched Description: … manufacturers typically convert the phenol component of the vitamin to esters using acetic or succinic acid ... d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and ... inflammation mediation [A32958] activities that are unique from the alpha-tocopherol form and other …
Matched Mixtures name: … Folic Acid Plus ... Co-q10 and Vitamin E ... Multi-Vitamin Fluoride and Iron Drops …
Matched Categories: … Diet, Food, and Nutrition …

Light green SF yellowish

Light green SF yellowish is a green triarylmethane dye that is used in the preparation of the staining solution which is widely used as a counterstain. It is used in histological applications and other labratory settings, and usually exists as a disodium salt. The maximum absorption of light green SF...
Approved
Experimental
Matched Synonyms: … Acid green ... Acid green 5 ... Acid Green A …
Matched Description: … It is used in histological applications and other labratory settings, and usually exists as a disodium ... discontinued from the market due to low popularity which are possibly due to low durability of the dye and …

Biotin

A water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.
Approved
Investigational
Nutraceutical
Matched Synonyms: … (+)-cis-Hexahydro-2-oxo-1H-thieno[3,4]imidazole-4-valeric acid ... cis-Hexahydro-2-oxo-1H-thieno(3,4)imidazole-4-valeric acid ... 5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid …
Matched Iupac: … 5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid …
Matched Description: … and milk. ... It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, …
Matched Mixtures name: … Folivane-Plus with Ascorbic Acid Precursors ... B-complex With Vitamin C, Biotin, Folic Acid ... Prenatal Vitamin No 53 Iron Fum Folic Acid Docusate CA DHA …
Matched Categories: … Enzymes and Coenzymes ... Diet, Food, and Nutrition ... Alimentary Tract and Metabolism …
Matched Products: … Biona-vit Controls and Prevents Hair Loss …

Tioguanine

An antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.
Approved
Matched Synonyms: … Thioguanine anhydrous ... Thioguanine, anhydrous …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Ornithine

Produced during the urea cycle, ornithine is an amino acid produced from the splitting off of urea from arginine. L-Ornithine allows for the disposal of excess nitrogen and acts as a precursor of citrulline and arginine.
Approved
Nutraceutical
Matched Synonyms: … (S)-2,5-diaminovaleric acid ... (S)-2,5-Diaminopentanoic acid ... (S)-α,δ-diaminovaleric acid …
Matched Iupac: … (2S)-2,5-diaminopentanoic acid …
Matched Description: … Produced during the urea cycle, ornithine is an amino acid produced from the splitting off of urea from ... L-Ornithine allows for the disposal of excess nitrogen and acts as a precursor of citrulline and arginine …
Matched Mixtures name: … PRIMENE 10% AMINO ACID INTRAVENOUS INFUSION …
Matched Categories: … Bile and Liver Therapy ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …

Tyrosine

Tyrosine is a non-essential amino acid. In animals it is synthesized from phenylalanine. It is also the precursor of epinephrine, thyroid hormones, and melanin.
Approved
Investigational
Nutraceutical
Matched Synonyms: … (−)-α-amino-p-hydroxyhydrocinnamic acid ... (2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid ... (S)-α-amino-4-hydroxybenzenepropanoic acid …
Matched Iupac: … (2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid …
Matched Description: … It is also the precursor of [epinephrine], thyroid hormones, and melanin. ... Tyrosine is a non-essential amino acid. In animals it is synthesized from [phenylalanine]. …
Matched Mixtures name: … Travasol Amino Acid Inj 8.5% ... Travasol Amino Acid Inj 5.5% ... Amino Acid InJ.W.elecw.25%dex …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Cidofovir

Cidofovir is an injectable antiviral medication employed in the treatment of cytomegalovirus (CMV) retinitis in patients diagnosed with AIDS. It suppresses CMV replication through selective inhibition of viral DNA synthesis.[FDA label] It was manufactured by Gilead and initially approved by the FDA in 1996, but has since been discontinued.
Approved
Matched Synonyms: … Cidofovir anhydrous ... (S)-(3-(4-amino-2-Oxopyrimidin-1(2H)-yl)-1-hydroxypropan-2-yloxy)methylphosphonic acid ... [(S)-2-(4-Amino-2-oxo-2H-pyrimidin-1-yl)-1-hydroxymethyl-ethoxymethyl]-phosphonic acid …
Matched Iupac: … ({[(2S)-1-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid …
Matched Description: … [FDA label] It was manufactured by _Gilead_ and initially approved by the FDA in 1996, but has since …
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …

Brilliant blue G

Brilliant Blue G is used in an ophthalmic solution for staining the internal limiting membrane (ILM) of the eye during ophthalmic procedures.[A188841,A188844] This membrane is thin and translucent, making it difficult to identify during eye surgeries that require high levels of visual accuracy. Brilliant blue G, like its name, imparts...
Approved
Matched Synonyms: … Acid Blue 90 ... Acid Blue 90 …
Matched Description: … [A188841,A188844] This membrane is thin and translucent, making it difficult to identify during eye surgeries …
Matched Categories: … Indicators and Reagents …

Benzyl benzoate

Benzyl benzoate is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei. It is characterised by severe itching (particularly at night), red spots, and may lead to a secondary infection. Benzyl benzoate is lethal to this mite and so...
Approved
Matched Synonyms: … Benzoic acid, benzyl ester ... Benzoic acid phenylmethylester ... Benzoic acid, phenylmethyl ester …
Matched Description: … It is also used to treat lice infestation of the head and body. ... Benzyl benzoate is lethal to this mite and so is useful in the treatment of scabies. ... It is characterised by severe itching (particularly at night), red spots, and may lead to a secondary …
Matched Categories: … Scabicides, Insecticides and Repellents ... Antiparasitic Products, Insecticides and Repellents …

Nicotinamide

An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
Approved
Investigational
Matched Synonyms: … Nicotinic acid amide …
Matched Description: … Its primary significance is in the prevention and/or cure of blacktongue and pellagra. ... Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and …
Matched Mixtures name: … Lactic Acid 10% / Niacinamide 4% ... Azelaic Acid 15% / Niacinamide 4% ... Iron Polysaccharides Folic Acid DHA …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Dr.g Lock and More A-clear Mask ... P8 Tone - Up and Brightening CreamEX ... HANSKIN BiO FILL PEP MASK Firming and Moisture …

Cysteine

A thiol-containing non-essential amino acid that is oxidized to form cystine.
Approved
Nutraceutical
Matched Synonyms: … (2R)-2-amino-3-mercaptopropanoic acid ... (2R)-2-amino-3-sulfanylpropanoic acid ... (R)-2-Amino-3-mercaptopropanoic acid …
Matched Iupac: … (2R)-2-amino-3-sulfanylpropanoic acid …
Matched Description: … A thiol-containing non-essential amino acid that is oxidized to form cystine. …
Matched Mixtures name: … Premasol - sulfite-free (Amino Acid) ... Premasol - sulfite-free (Amino Acid) ... PRIMENE 10% AMINO ACID INTRAVENOUS INFUSION …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Sodium ascorbate

Approved
Nutraceutical
Matched Synonyms: … Ascorbic acid sodium salt ... L-Ascorbic acid sodium salt ... L-Ascorbic acid, monosodium salt …
Matched Mixtures name: … Peg-3350, Sodium Sulfate, Sodium Chloride, Potassium Chloride, Sodium Ascorbate and Ascorbic Acid ... PEG-3350, Electrolytes, and Ascorbate ... Bugs Bunny and Friends Multiple Vitamins …
Matched Categories: … Vitamin C and analogues ... Diet, Food, and Nutrition …
Displaying drugs 2951 - 2975 of 15149 in total