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Displaying drugs 276 - 300 of 3593 in total
Fexofenadine is an over-the-counter second-generation antihistamine used in the treatment of various allergic symptoms. It is selective for the H1 receptor, carries little-to-no activity at off-targets, and does not cross the blood-brain barrier - this is in contrast to previous first-generation antihistamines, such as diphenhydramine, which readily bind to off-targets...
Approved
Investigational
Matched Synonyms: … 4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)butyl)-alpha,alpha-dimethylbenzeneacetic acid ... Terfenadine acid metabolite …
Matched Iupac: … 2-(4-{1-hydroxy-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butyl}phenyl)-2-methylpropanoic acid
Matched Description: … L4269] It is selective for the H1 receptor, carries little-to-no activity at off-targets, and ... [A1452] Fexofenadine is the major active metabolite of [terfenadine][A1495] and is administered as a …
Matched Mixtures name: … FEXOFENADINE HYDROCHLORIDE and PSEUDOEPHEDRINE HYDROCHLORIDE ... FEXOFENADINE HYDROCHLORIDE and PSEUDOEPHEDRINE HYDROCHLORIDE ... FEXOFENADINE HYDROCHLORIDE and PSEUDOEPHEDRINE HYDROCHLORIDE
Matched Salts name: … Fexofenadine hydrochloride
Matched Products: … Up and Up Allergy Relief ... Berkley and Jensen Allergy Relief ... Up and Up Non Drowsy Allergy Relief …
Bismuth subsalicylate is an antacid and anti-diarrheal agent. Exhibiting antibacterial and gastroprotective properties, bismuth subsalicylate is an insoluble salt of salicylic acid linked to trivalent bismuth cation. Each molecule of bismuth subsalicylate contains 58% bismuth and 42% salicylate by weight. Bismuth subsalicylate has been around for over 100 years: it...
Approved
Vet approved
Matched Synonyms: … Bismuth oxide salicylate …
Matched Description: … of [salicylic acid] linked to trivalent [bismuth cation]. ... Bismuth subsalicylate is an antacid and anti-diarrheal agent. ... Exhibiting antibacterial and gastroprotective properties, bismuth subsalicylate is an insoluble salt …
Matched Mixtures name: … Bismuth Tablets With Calcium Carbonate ... Chewable Bismuth Tablets With Calcium Carbonate ... Pepto-Bismol and Pepto-Bismol To Go …
Matched Categories: … Antacids and Adsorbents ... Acids, Carbocyclic ... Carboxylic Acids ... Hydroxy Acids
Matched Products: … Up and Up Stomach Relief ... Up and Up Digestive Relief ... Up and Up 5-symptom Digestive Relief …
Phenazopyridine, also known as Pyridium, is a urinary tract analgesic used for the short-term management of urinary tract irritation and its associated unpleasant symptoms such as burning and pain during urination. In the USA, this drug was previously marked by Roche but has been discontinued by the FDA. It is...
Approved
Matched Synonyms: … 2,6-Diamino-3-(phenylazo)pyridine
Matched Iupac: … 3-[(1E)-2-phenyldiazen-1-yl]pyridine-2,6-diamine …
Matched Description: … its associated unpleasant symptoms such as burning and pain during urination. ... Pyridium, is a urinary tract analgesic used for the short-term management of urinary tract irritation and
Matched Mixtures name: … Phenazopyridine Hydrochloride, Hyoscyamine Hydrobromide, and Butabarbital …
Matched Salts name: … Phenazopyridine hydrochloride
Matched Categories: … Antipruritics and Local Anesthetics ... Genito Urinary System and Sex Hormones …
Matched Products: … Foster and Thrive Maximum Strength Urinary Pain Relief ... Foster and Thrive Neighbor Pharmacy Urinary Pain Relief ... Phenazopyridine Hydrochloride
Tarlatamab is a first-in-class T-cell engager used to treat extensive-stage small cell lung cancer. It is a bispecific monoclonal antibody that targets CD3 expressed on the surface of T-cells and delta-like ligand 3 (DLL3), an inhibitory ligand that suppresses Notch signaling and is highly expressed across various SCLC disease stages...
Approved
Investigational
Matched Synonyms: … Immunoglobulin scfv-scfv-scfc, anti-(homo sapiens dll3 (delta-like ligand 3)) and anti-(homo sapiens ... Tarlatamab-dlle
Matched Description: … delta-like ligand 3 (DLL3), an inhibitory ligand that suppresses Notch signaling and is highly expressed ... across various SCLC disease stages and treatment statuses. ... L50748] It is a bispecific monoclonal antibody that targets CD3 expressed on the surface of T-cells and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … immunoglobulin g1 (igg1) t-cell bispecific (tcb) antibody targeting carcinoembryonic antigen (cea) and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Dabocemagene autoficel is an ex vivo, autologous cell-based gene therapy. It comprises autologous dermal fibroblasts genetically modified to express functional type VII collagen. Developed by Castle Creek Biosciences Inc., dabocemagene autoficel is being investigated for the treatment of dystrophic epidermolysis bullosa.
Investigational
Matched Synonyms: … AUTOLOGOUS HUMAN DERMAL FIBROBLAST CELLS DERIVED FROM SKIN BIOPSIES, AND TRANSDUCED WITH A NON-REPLICATING ... INTEGRATED PROVIRAL HUMAN COLLAGEN TYPE VII TRANSGENE COL7A1 PLUS 5'-HUMAN CYTOMEGALOVIRUS PROMOTER/UTR-AND ... , SELF-INACTIVATING LENTIVIRUS VECTOR THAT ENCODES HUMAN COLLAGEN TYPE VII ALPHA 1 (COL7A1) UNDER THE …
Pyrethrum is the crude extract form obtained from flowers of the plant Chrysanthemum cinerariifolium. Pyrethrin refers to a more refined extract of pyrethrum. While pyrethrum extract is composed of 6 esters, both organic compounds mediate insecticidal activities. Pyrethrum-containing mixtures are used as a common insecticide to control specific pest species....
Approved
Matched Synonyms: … Pyrethrins and pyrethroids …
Matched Description: … Pyrethrum extract is also used used to treat head, body, and pubic lice infections. ... The active compound is absorbed by the lice and destroys them by acting on their nervous systems but …
Matched Mixtures name: … Lice-Nil Lice and Eggs Killer ... Medi and Lice Lice Killing ... Weeks and Leo Complete Lice Treatment …
Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral alpha (α)-adrenergic properties. Available since the 1950s, tetryzoline is a selective α1-receptor agonist that is used as an ocular and nasal decongestant. Tetryzoline is found in a wide array of over-the-counter eye drops, including the most...
Approved
Matched Description: … alpha (α)-adrenergic properties. ... Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral ... such as [povidone], [polyethylene glycol 400], [dextran], and [zinc sulfate]. …
Matched Mixtures name: … Redness reliever and Lubricant ... Seasonal itchy and Red eye relief ... Up and Up Ultra Itchy Relief …
Matched Salts name: … Tetrahydrozoline hydrochloride
Matched Categories: … Decongestants and Antiallergics ... Adrenergic alpha-Agonists ... Adrenergic alpha-1 Receptor Agonists …
Matched Products: … Walgreens Eye Drops Original 15mL and twin pack ... Foster and Thrive Original Formula Eye Drops …
Xylometazoline is an imidazoline derivative with sympathomimetic and nasal decongestant activity. Xylometazoline works by binding to alpha (α)-adrenergic receptors to cause vasoconstriction of nasal blood vessels. Xylometazoline is available in over-the-counter (OTC) nasal sprays or drops to temporarily relieve nasal congestion due to cold, hay fever or other respiratory allergies....
Approved
Investigational
Matched Description: … Xylometazoline is an imidazoline derivative [A228523] with sympathomimetic and nasal decongestant activity ... Xylometazoline works by binding to alpha (α)-adrenergic receptors to cause vasoconstriction of nasal …
Matched Salts name: … Xylometazoline hydrochloride
Matched Categories: … Decongestants and Antiallergics ... Calcium Channel Blockers ... Adrenergic alpha-Agonists ... Adrenergic alpha-1 Receptor Agonists ... Adrenergic alpha-2 Receptor Agonists …
Matched Products: … Cold and Allergy Decongestant Nasal Spray ... Otrivin Cold and Allergy Decongestant Nose Drops ... Otrivin Allergy and Cold Decongestant Nasal Spray …
Garcinia gummi-gutta fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Garcinia Cambogia (Constituent of Garcinia Cambogia and Garcinia Indica) …
DCLL9718S is an antibody-drug conjugate targeting C-type lectin-like molecule-1 (CLL-1). DCLL9718S is under investigation in clinical trial NCT03298516 (A Study of DCLL9718S in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) or DCLL9718S in Combination With Azacitidine in Participants With Previously Untreated AML Unsuitable for Intensive Induction Chemotherapy).
Investigational
Matched Synonyms: … antibody drug conjugate comprised of humanized IgG1 anti-C-type lectin-like molecule-1 monoclonal antibody and
Matched Categories: … Amino Acids, Peptides, and Proteins …
This drug is a broad spectrum antimycotic or antifungal agent. Clotrimazole's antimycotic properties were discovered in the late 1960s . Clotrimazole falls under the imidazole category of azole antifungals, possessing broad-spectrum antimycotic activity . It is available in various preparations, including creams, pessaries, and troche formulations (slowly dissolving tablets). As...
Approved
Vet approved
Matched Description: … It is available in various preparations, including creams, pessaries, and troche formulations (slowly ... has become a drug of interest in treating several other diseases such as sickle cell disease, malaria and ... The minimal side effect profile of this drug and its uncomplicated metabolic profile have led it to gain …
Matched Mixtures name: … CLOTRIMAZOL ACIS 3 KOMBI ... CLOTRIMAZOL ACIS 3 KOMBI ... Clotrimazole and Betamethasone Dipropionate …
Matched Categories: … Antiinfectives and Antiseptics for Local Oral Treatment ... Imidazole and Triazole Derivatives ... Gynecological Antiinfectives and Antiseptics ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … CALCREM ... Terrasil Foot and Nail Anti-Fungal ... Up and Up Jock Itch Relief …
Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and secreted by the somatotropic cells of the anterior pituitary gland. Growth hormone plays an essential role in growth regulation during childhood as well as other basal metabolic functions, muscle and fat mass regulation, blood...
Approved
Investigational
Matched Description: … in a strain of _Escherichia coli_, recombinant HGH is a polypeptide hormone that contains 191 amino acid ... fat mass regulation, blood glucose level regulation, and lipid regulation in both children and adults ... Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Anterior Pituitary Lobe Hormones and Analogues ... Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Somatropin and Somatropin Agonists …
Matched Products: … GENOTROPIN® 12MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... GENOTROPIN® 5.3MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ZOMACTON Powder and Solvent for Solution for Injection 10mg …
Dexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Dexpanthenol is enzymatically cleaved to form pantothenic acid, which is an essential component of Coenzyme A, which acts as a cofactor in many enzymatic reactions that...
Approved
Matched Description: … Dexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and ... Due to its good penetration and high local concentrations, dexpanthanol is used in many topical products ... , such as ointments and lotions for treatment of dermatological conditions to relieve itching or promote …
Matched Mixtures name: … Somarexin and C 1000 ... B Complex W C and B12 Inj ... CH6 Perfumed Aloforthya Peony and the sunset …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Alimentary Tract and Metabolism ... Vitamin D and Analogues ... Preparations for Treatment of Wounds and Ulcers …
Matched Products: … Eros Aqua Sensations and Care Woman ... DEXPANTHENOL ACIS WUND+HEI …
Insulin aspart is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … with aspartic acid. ... body starts to break down fat, instead of glucose, for energy which results in a build-up of ketone acids ... Compared to human insulin, it has a single amino acid substitution at position B28 where proline is replaced …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... insulin degludec and insulin aspart ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Insulins and Analogues for Injection, Fast-Acting …
Matched Products: … Insulin Aspart Protamine and Insulin Aspart Mix 70/30 ... .Insulin Aspart Protamine and Insulin Aspart …
Originally approved by the FDA in 1989, omeprazole is a proton-pump inhibitor, used to treat gastric acid-related disorders. These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases characterized by the oversecretion of gastric acid. This drug was the first clinical useful drug in its class,...
Approved
Investigational
Vet approved
Matched Description: … characterized by the oversecretion of gastric acid. ... Omeprazole is generally effective and well-tolerated, promoting its popular use in children and adults ... These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases …
Matched Mixtures name: … Zegerid with Magnesium Hydroxide ... Zegerid with Magnesium Hydroxide ... Omeprazole, Sodium Bicarbonate, Magnesium Hydroxide …
Matched Salts name: … Omeprazole magnesium
Matched Categories: … Acid Reducers ... Medications that reduce magnesium levels ... Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders ... Alimentary Tract and Metabolism …
Matched Products: … Up and Up Omeprazole ... Berkley and Jensen Omeprazole ... Foster and Thrive Omeprazole …
Hydrochlorothiazide is the most commonly prescribed thiazide diuretic. It is indicated to treat edema and hypertension.[A185138,L8447,L8450] Hydrochlorothiazide use is common but declining in favour of angiotensin converting enzyme inhibitors. Many combination products are available containing hydrochlorothiazide and angiotensin converting enzyme inhibitors[L8390,L8423] or angiotensin II receptor blockers.[L7426,L7459] Hydrochlorothiazide was granted FDA...
Approved
Vet approved
Matched Description: … [A185138] It is indicated to treat edema and hypertension. ... [A185138] Many combination products are available containing hydrochlorothiazide and angiotensin converting …
Matched Mixtures name: … RAMIPRIL BETA COMP 5/25MG ... RAMIPRIL BETA COMP2.5/12.5 ... Co-Acetan - Tabletten …
Matched Categories: … hydrochlorothiazide and potassium ... Low-Ceiling Diuretics and Potassium-Sparing Agents ... hydrochlorothiazide and potassium-sparing agents ... Medications that reduce magnesium levels ... Non Potassium Sparing Diuretics …
Matched Products: … Losartan Potassium and Hydrochlorothiazide ... HCT BETA 25 ... HCT BETA 12.5 …
Mucor circinelloides f. lusitanicus allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, mucor circinelloides f. lusitanicus …
Investigational
Matched Synonyms: … antibody-drug conjugate comprised of a human aglycosylated anti-CD74 IgG1 antibody (SP7219) and two non-cleavable …
PRGN-3006 are autologous CD3+ T cells genetically modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and a truncated form of human HER1T (kill switch) on the cell surface.
Investigational
Matched Synonyms: … genetically modified using a non-viral system to express a CD33 CAR, membrane bound Interleukin-15, and
Matched Description: … genetically modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and
Investigational
Matched Synonyms: … recombinant adeno-associated viral (AAV) vector that contains a bio-engineered capsid (AAV-Spark100) and ... a codon-optimized expression cassette to drive expression of a secretable form of human acid a-glucosidase …
Investigational
Matched Synonyms: … , mixture of three isomers a, b and c (25%, 50%, 25%) ... 4,4'-(15,20-diphenyl-7,8(or 12,13 or 17,18)-dihydro-21h,23h-porphine-5,10-diyl)bisbenzenesulfonic acid ... Benzenesulfonic acid, 4,4'-(7,8(or 17,18)-dihydro-10,15(or 15,20)-diphenyl-21h,23h-porphine-5,20(or 5,10 …
Demplatin pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and Gemcitabine Versus Gemcitabine Alone in Pancreatic Cancer).
Investigational
Matched Synonyms: … A micelle drug formulation composed of cisplatin and mPEG-poly(l-Glu) diblock copolymer with 1,3-propanediyl …
Matched Description: … pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Amino Acids, Dicarboxylic …
Approved
Investigational
Matched Synonyms: … Aluminum acetate
Matched Name: … Aluminum acetate
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
Matched Products: … ACID MANTLECREMA ... ACID MANTLE NLOCION ... ACID MANTLE N LOCION …
evorpacept is under investigation in clinical trial NCT04755244 (A Study of Evorpacept (ALX148) With Venetoclax and Azacitidine for Acute Myeloid Leukemia (ASPEN-05)).
Investigational
Matched Synonyms: … (SIRPalpha) variant 1 (v1) genetically linked to a modified and inactive Fc domain of human IgG ... , fusion protein containing a high affinity engineered D1 domain of human signal regulatory protein alpha
Matched Description: … is under investigation in clinical trial NCT04755244 (A Study of Evorpacept (ALX148) With Venetoclax and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 276 - 300 of 3593 in total