Displaying drugs 276 - 300 of 10800 in total
Varenicline
Varenicline is a prescription medication used to treat smoking addiction. This medication is the first approved nicotinic receptor partial agonist. Specifically, varenicline is a partial agonist of the alpha4/beta2 subtype of the nicotinic acetylcholine receptor. In addition it acts on alpha3/beta4 and weakly on alpha3beta2 and alpha6-containing receptors. A full...
Approved
Investigational
Matched Mixtures name: … CHAMPIX 0,5 MG 11 + 1 MG 42 FILM KAPLI TABLET ... CHAMPIX 0,5 MG 11 + 1 MG 42 FILM KAPLI TABLET ... CHAMPIX 0,5 MG 1 MG FILM KAPLI TABLET, 11 VE 14 ADET …
Matched Products: … และ 1 มก.) ... แชมปิกซ์ (1 มก.) ... CHAMPIX 1 MG FILM KAPLI TABLET, 28 ADET …
Matched Products: … และ 1 มก.) ... แชมปิกซ์ (1 มก.) ... CHAMPIX 1 MG FILM KAPLI TABLET, 28 ADET …
Lopinavir
Lopinavir is an antiretroviral protease inhibitor used in combination with other antiretrovirals in the treatment of HIV-1 infection. Lopinavir is marketed and administered exclusively in combination with ritonavir - this combination, first marketed by Abbott under the brand name Kaletra in 2000, is necessary due to lopinavir's poor oral bioavailability...
Approved
Matched Iupac: … [2-(2,6-dimethylphenoxy)acetamido]-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1- …
Matched Description: … Lopinavir was previously under investigation in combination with ritonavir for the treatment of COVID-19 ... antiretroviral protease inhibitor used in combination with other antiretrovirals in the treatment of HIV-1 ... protease enzyme but which itself cannot be cleaved, thus preventing the activity of the HIV-1 protease …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Experimental Unapproved Treatments for COVID-19 …
Matched Description: … Lopinavir was previously under investigation in combination with ritonavir for the treatment of COVID-19 ... antiretroviral protease inhibitor used in combination with other antiretrovirals in the treatment of HIV-1 ... protease enzyme but which itself cannot be cleaved, thus preventing the activity of the HIV-1 protease …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Experimental Unapproved Treatments for COVID-19 …
Phenylephrine
Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil, and induce local vasoconstriction. The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s. Phenylephrine was granted FDA approval in 1939.
Approved
Matched Iupac: … 3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol …
Matched Description: … Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate …
Matched Salts cas: … 1416-03-1 …
Matched Mixtures name: … Goyescas Broncovac 1 Cough and Cold ... PRAMOFEN %1 + % 0,25 KREM, 50 GRAM ... OLEDRO 32/ 1/ 0,2 MG/ML PEDIATRIK SURUP, 100 ML …
Matched Categories: … Adrenergic alpha-1 Receptor Agonists …
Matched Products: … Neo-synephrine Liq 1% ... Neo Synephrine Nasal Drop 1% ... Neo-synephrine Nasal Drop 1% …
Matched Description: … Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate …
Matched Salts cas: … 1416-03-1 …
Matched Mixtures name: … Goyescas Broncovac 1 Cough and Cold ... PRAMOFEN %1 + % 0,25 KREM, 50 GRAM ... OLEDRO 32/ 1/ 0,2 MG/ML PEDIATRIK SURUP, 100 ML …
Matched Categories: … Adrenergic alpha-1 Receptor Agonists …
Matched Products: … Neo-synephrine Liq 1% ... Neo Synephrine Nasal Drop 1% ... Neo-synephrine Nasal Drop 1% …
Nabilone
Nabilone (marketed as Cesamet) is a synthetic form of delta-9-tetrahydrocannabinol (Δ⁹-THC), the primary psychoactive component of cannabis (marijuana). Although structurally distinct from THC, nabilone mimics THC's structure and pharmacological activity through weak partial agonist activity at Cannabinoid-1 (CB1R) and Cannabinoid-2 (CB2R) receptors, however it is considered to be twice as...
Approved
Investigational
Matched Iupac: … (6aR,10aR)-1-hydroxy-6,6-dimethyl-3-(2-methyloctan-2-yl)-6H,6aH,7H,8H,9H,10H,10aH-benzo[c]isochromen- …
Matched Description: … mimics THC's structure and pharmacological activity through weak partial agonist activity at Cannabinoid-1 …
Matched Products: … Canemes 1 mg Kapseln …
Matched Description: … mimics THC's structure and pharmacological activity through weak partial agonist activity at Cannabinoid-1 …
Matched Products: … Canemes 1 mg Kapseln …
Terlipressin
Terlipressin is a synthetic analogue of vasopressin, which is an endogenous neurohormone that acts as a vasoconstrictor. It is a prodrug of lypressin, or lysine vasopressin. Compared to endogenous vasopressin, terlipressin has a longer half life and increased selectivity for the V1 receptor. As a potent vasopressor, terlipressin has been...
Approved
Investigational
Matched Products: … HAEMOPRESSIN® 1 MG ... GLYPRESSIN ® 1 MG ... GLYPRESSIN 1 MG IV ENJEKSIYONLUK TOZ IÇEREN FLAKON VE ÇÖZÜCÜ AMPUL, 1 ADET …
Iodohippurate sodium I-131
Approved
Ethylhexyl methoxycrylene
Ethylhexyl methoxycrylene is a photostabilizer that preserves the effectiveness of UV filters by interacting with both the singlet and triplet states . It returns UV filters to their ground states without absorbing sunlight . It is used as a solvent for crystalline UV filters and is easily emulsified and suitable...
Approved
Experimental
Upadacitinib
Upadacitinib is an oral Janus kinase (JAK)1-selective inhibitor and a disease-modifying antirheumatic drug (DMARD) used in the treatment of rheumatoid arthritis to slow down disease progression. Rheumatoid arthritis is a chronic autoimmune inflammatory disease affecting the peripheral joints. It is characterized by synovial inflammation and hyperplasia, autoantibody production, cartilage damage...
Approved
Investigational
Matched Iupac: … tetraazatricyclo[7.3.0.0^{2,6}]dodeca-2(6),3,7,9,11-pentaen-12-yl}-N-(2,2,2-trifluoroethyl)pyrrolidine-1- …
Matched Description: … Upadacitinib is an oral Janus kinase (JAK)1-selective inhibitor and a disease-modifying antirheumatic ... [A189165] The FDA approved upadacitinib in August 2019 and it is used for the treatment of active ... [L10896] In December 2019, it was additionally approved by the European Commission and Health Canada. …
Matched Description: … Upadacitinib is an oral Janus kinase (JAK)1-selective inhibitor and a disease-modifying antirheumatic ... [A189165] The FDA approved upadacitinib in August 2019 and it is used for the treatment of active ... [L10896] In December 2019, it was additionally approved by the European Commission and Health Canada. …
Amylmetacresol
Amylmetacresol is an antiseptic available in Canada over-the-counter in a number of lozenges for the treatment of sore throat and minor mouth infections , . Amylmetacresol is often combined with dichlorobenzyl alcohol and menthol in the commonly used sore throat lozenges, known as Strepsils .
The acute sore throat (pharyngitis)...
Approved
Matched Products: … Strepsils 1 - Loz …
Velaglucerase alfa
Velaglucerase alfa is a gene-activated human recombinant glucocerebrosidase used for the treatment of Type 1 Gaucher disease, caused by a deficiency of the lysosomal enzyme glucocerebrosidase. Additionally, Velaglucerase alfa has also been investigated for use in Type 3 Gaucher disease.
Approved
Investigational
Matched Description: … Velaglucerase alfa is a gene-activated human recombinant glucocerebrosidase used for the treatment of Type 1 …
Matched Products: … VPRIV 400 ÜNİTE İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADET …
Matched Products: … VPRIV 400 ÜNİTE İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADET …
Vinorelbine
Vinorelbine is an anti-mitotic chemotherapy drug that is used in the treatment of several types of malignancies, including breast cancer and non-small cell lung cancer (NSCLC) . It was initially approved in the USA in 1990's for the treatment of NSCLC .
It is a third-generation vinca alkaloid. The introduction...
Approved
Investigational
Matched Products: … RENOVEL 10 MG/1 ML IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET ... NAVELBINE 20 MG YUMUSAK KAPSUL, 1 ADET ... NAVELBINE 30 MG YUMUSAK KAPSUL, 1 ADET …
Tacrolimus
Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug whose main use is after organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It is also used in a topical preparation in the treatment of severe atopic dermatitis, severe refractory uveitis...
Approved
Investigational
Matched Iupac: … ]prop-1-en-2-yl]-23,25-dimethoxy-13,19,21,27-tetramethyl-17-(prop-2-en-1-yl)-11,28-dioxa-4-azatricyclo ... (1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-1,14-dihydroxy-12-[(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl …
Matched Mixtures name: … Hyaluronic Acid Sodium Salt 1% / Tacrolimus 0.1% / Urea 20% ... Hyaluronic Acid Sodium Salt 1% / Niacinamide 4% / Tacrolimus 0.1% …
Matched Products: … Tacrocord 1 Capsules 1 mg ... TACROCIN 1- TACROLIMUS CAPSULE USP 1 MG ... TACLIM 1 MG …
Matched Mixtures name: … Hyaluronic Acid Sodium Salt 1% / Tacrolimus 0.1% / Urea 20% ... Hyaluronic Acid Sodium Salt 1% / Niacinamide 4% / Tacrolimus 0.1% …
Matched Products: … Tacrocord 1 Capsules 1 mg ... TACROCIN 1- TACROLIMUS CAPSULE USP 1 MG ... TACLIM 1 MG …
Estradiol valerate
Estradiol Valerate (also known as E2V) is a pro-drug ester of DB00783, a naturally occurring hormone that circulates endogenously within the human body. Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex hormone. As a pro-drug of estradiol, estradiol acetate therefore...
Approved
Investigational
Vet approved
Matched Iupac: … 3bR,9bS,11aS)-7-hydroxy-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1- …
Matched Mixtures name: … DIVICONT TABLETAS 1 MG/5 MG ... DIVICONT TABLETAS 1 MG/2.5 MG ... Velbienne 1 mg/2 mg Filmtabletten …
Matched Products: … โปรกีโนวา 1 มก. ... PROGYNOVA 1 MG. ... MERIESTRA ® 1 MG …
Matched Mixtures name: … DIVICONT TABLETAS 1 MG/5 MG ... DIVICONT TABLETAS 1 MG/2.5 MG ... Velbienne 1 mg/2 mg Filmtabletten …
Matched Products: … โปรกีโนวา 1 มก. ... PROGYNOVA 1 MG. ... MERIESTRA ® 1 MG …
Methylcellulose
Methyl cellulose polymer consisting of numerous linked glucose molecules used as a stabiliser, thickener and emulsifier for foodstuffs and cosmetics. The Degree of Substitution (DS) of a given form of methyl cellulose is defined as the average number of substituted hydroxyl groups per glucose with a theoretical maximum of 3,...
Approved
Matched Products: … Murocel Liq 1% …
Tafamidis
Tafamidis and tafamidis meglumine (FX-1006A) are benzoxazole derivatives developed by FoldRX. Tafamidis is structurally similar to diflusinal. Tafamidis was granted an EMA market authorisation on 16 November 2011 and FDA approval on 3 May 2019.
Approved
Investigational
Matched Description: … Tafamidis was granted an EMA market authorisation on 16 November 2011[L6247] and FDA approval on 3 May 2019 …
Ceftazidime
Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis,...
Approved
Matched Iupac: … 1-{[(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetamido]-2-carboxylato ... -8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}pyridin-1-ium …
Matched Description: … [L32935] Ceftazidime was approved by the FDA on July 19, 1985, and is currently available either alone …
Matched Mixtures name: … CEFAZIME FOR INJECTION 1 g/vial …
Matched Products: … IESETUM 1 G IV/IM ENJEKTABL FLAKON, 1 ADET ... SEFAVİS 1 G IM/IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 FLAKON VE 1 AMPUL ... FORTUM INYECTABLE 1 G …
Matched Description: … [L32935] Ceftazidime was approved by the FDA on July 19, 1985, and is currently available either alone …
Matched Mixtures name: … CEFAZIME FOR INJECTION 1 g/vial …
Matched Products: … IESETUM 1 G IV/IM ENJEKTABL FLAKON, 1 ADET ... SEFAVİS 1 G IM/IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 FLAKON VE 1 AMPUL ... FORTUM INYECTABLE 1 G …
Rotavirus vaccine
Rotavirus commonly infects children and infants causing severe diarrhea and vomiting leading to potentially fatal dehydration. Two rotavirus vaccines are available for the prevention of rotavirus gastroenteritis, Rotateq and Rotarix. Rotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains. Rotarix is a live attenuated vaccine containing the...
Approved
Matched Products: … ROTARIX ORAL SÜSPANSIYON HAZIRLAMAK IÇIN LIYOFILIZE TOZ IÇEREN FLAKON, 1 ADET …
Autologous peripheral blood-derived CD34+ cells
Autologous peripheral blood-derived CD34+ cells, or CLBS119 (a proprietary version being developed by Caladrius Biosciences, Inc.), are hematopoietic stem cells. It is also a cell therapy being investigated by Caladrius Biosciences in the clinical trial NCT04522817 (CLBS119 for Repair of COVID-19 Induced Pulmonary Damage).
Approved
Investigational
Matched Description: … investigated by Caladrius Biosciences in the clinical trial NCT04522817 (CLBS119 for Repair of COVID-19 …
Solriamfetol
Solriamfetol marketed under the brand name Sunosi by Jazz Pharmaceuticals in the United States is a dopamine and norepinephrine reuptake inhibitor (DNRI) indicated in treating daytime sleepiness associated with narcolepsy or obstructive sleep apnea[FDA Label]. Solriamfetol was given FDA approval in 2019[FDA Label].
Approved
Matched Description: … Solriamfetol was given FDA approval in 2019[FDA Label]. …
Matched Categories: … MATE 1 Substrates …
Matched Categories: … MATE 1 Substrates …
Glimepiride
First introduced in 1995, glimepiride is a member of the second-generation sulfonylurea (SU) drug class used for the management of type 2 diabetes mellitus (T2DM) to improve glycemic control. Type 2 diabetes is a metabolic disorder with increasing prevalences worldwide; it is characterized by insulin resistance in accordance with progressive...
Approved
Matched Iupac: … -(2-{4-[({[(1r,4r)-4-methylcyclohexyl]carbamoyl}amino)sulfonyl]phenyl}ethyl)-2,5-dihydro-1H-pyrrole-1- …
Matched Mixtures name: … GLUCOVEL 1 ... VELACOM PLUS 1/250 ... AMARYL®M 1 MG/ 500 MG …
Matched Products: … DIAPRIDE-1 TABLET 1 mg ... GLUVAS 1 ... VELACOM 1 …
Matched Mixtures name: … GLUCOVEL 1 ... VELACOM PLUS 1/250 ... AMARYL®M 1 MG/ 500 MG …
Matched Products: … DIAPRIDE-1 TABLET 1 mg ... GLUVAS 1 ... VELACOM 1 …
Hepatitis B Vaccine (Recombinant)
Hepatitis B Vaccine is an ingredient in the EMA-withdrawn product Quintanrix. It is marketed in Canada as Engerix B. It is also a part of Twinrix (Hep A/Hep B vaccine) available also in Canada.
The hepatitis B virus induces a severe form of viral hepatitis. Other causative agents are hepatitis...
Approved
Withdrawn
Matched Salts cas: … 351186-51-1 …
Matched Mixtures name: … HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 1 ADET ... TWINRIX ERİŞKİN IM 1 ML SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR ... HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET …
Matched Products: … EUVAX-B 1 ML FLAKON, 1 ADET ... HBVAXPRO ERİŞKİN 10 MCG/1 ML IM ENJEKSİYON İÇİN SUSPANSİYON İÇEREN FLAKON, 1 ADET ... EUVAX-B 0,5 ML FLAKON, 1 ADET …
Matched Mixtures name: … HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 1 ADET ... TWINRIX ERİŞKİN IM 1 ML SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR ... HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET …
Matched Products: … EUVAX-B 1 ML FLAKON, 1 ADET ... HBVAXPRO ERİŞKİN 10 MCG/1 ML IM ENJEKSİYON İÇİN SUSPANSİYON İÇEREN FLAKON, 1 ADET ... EUVAX-B 0,5 ML FLAKON, 1 ADET …
Denosumab
Denosumab is a novel, fully human IgG2 monoclonal antibody specific to receptor activator of nuclear factor kappa-B ligand (RANKL), suppresses bone resorption via inhibiting RANK-mediated activation of osteoclasts. It is the first and currently the only RANKL inhibitor approved to prevent osteoclast-mediated bone loss. Chemically, it consists of 2 heavy...
Approved
Matched Products: … ENJEKSIYONLUK COZELTI ICEREN FLAKON, 1 ADET ... PROLIA 60 MG/ML SC ENJEKSIYONLUK COZELTI ICEREN KULLANIMA HAZIR ENJEKTOR, 1 ADET ... PROLİA 60 MG/ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET …
Fluconazole
Fluconazole, commonly known as Diflucan, is an antifungal drug used for the treatment of both systemic and superficial fungal infections in a variety of tissues. It was initially approved by the FDA in 1990. This drug is an azole antifungal, in the same drug family as ketoconazole and itraconazole. Fluconazole...
Approved
Investigational
Matched Iupac: … 2-(2,4-difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol …
Matched Mixtures name: … Ciclopirox 8% / Fluconazole 1% / Terbinafine HCl 1% ... Canesoral Combi 1 Day ... Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4% …
Matched Products: … CANDIMAX 150 MG KAPSUL, 1 ADET ... İNFÜZYONLUK ÇÖZELTİ, 1 ADET ... FLUCORAL 150 MG KAPSÜL, 1 ADET …
Matched Mixtures name: … Ciclopirox 8% / Fluconazole 1% / Terbinafine HCl 1% ... Canesoral Combi 1 Day ... Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4% …
Matched Products: … CANDIMAX 150 MG KAPSUL, 1 ADET ... İNFÜZYONLUK ÇÖZELTİ, 1 ADET ... FLUCORAL 150 MG KAPSÜL, 1 ADET …
Certolizumab pegol
Certolizumab pegol is a pegylated monoclonal antibody against the tumor necrosis factor-alpha (TNF-alpha). It is formed with a humanized Fab fragment of 50 kDa, from an IgG 1 isotype, fused to a 40 kDa polyethylene glycol moiety replacing the Fc antibody region. The absence of the Fc region was ideated...
Approved
Matched Description: … [A176585] It is formed with a humanized Fab fragment of 50 kDa, from an IgG 1 isotype, fused to a 40 ... manufactured by UCB Pharma, first FDA approved in 2008[L45018] and updated for a new indication on March 28, 2019 …
Troglitazone
Troglitazone was withdrawn in 2000 due to risk of hepatotoxicity. It was superseded by pioglitazone and rosiglitazone.
Approved
Investigational
Withdrawn
Matched Iupac: … 5-({4-[(6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-1-benzopyran-2-yl)methoxy]phenyl}methyl)-1,3-thiazolidine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 276 - 300 of 10800 in total