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Displaying drugs 276 - 300 of 9713 in total

Sulfasalazine

Sulfasalazine is an anti-inflammatory drug structurally related to salicylates and other non-steroidal anti-inflammatory drugs. It is indicated for managing inflammatory diseases such as ulcerative colitis and rheumatoid arthritis (RA).[L39065, A255582] Metabolized by intestinal bacteria, sulfasalazine is broken down into mesalazine and sulfapyridine, 2 compounds that carry out the main pharmacological...
Approved
Matched Description: … [A255582] Sulfasalazine fell out of favor as the drug of choice for RA due to poorly designed clinical ... is not FDA-recommmended for treatment of Crohn's disease. ... into [mesalazine] and [sulfapyridine], 2 compounds that carry out the main pharmacological activity of …
Matched Categories: … combinations of sulfonamides …

Sofosbuvir

Sofosbuvir (tradename Sovaldi) is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the...
Approved
Matched Description: … therapy of 93-99% depending on genotype and level of cirrhosis [L852]. ... Lack of significant side effects and short duration of therapy is a considerable advantage over older ... reduced liver-related damage, improved quality of life, reduced incidence of Hepatocellular Carcinoma …
Matched Categories: … Antivirals for treatment of HCV infections …

Chlorhexidine

Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms. It is one of the most common skin and mucous membrane antiseptic agents in use today. The molecule itself is a cationic bis-guanide consisting of...
Approved
Vet approved
Withdrawn
Matched International brands: … Prevacare R …
Matched Description: … of this product. ... [L43942,L44027] Other formulations of chlorhexidine continue to be available. ... [L11512] It is one of the most common skin and mucous membrane antiseptic agents in use today. …
Matched Mixtures name: … TANTUM VERDE DUO 22,5 MG+18 MG/15 ML GARGARA ... TANTUM VERDE DUO FORTE 45 MG+18 MG/15 ML GARGARA …

Beroctocog alfa

Approved
Investigational
Matched Mixtures name: … OPTIVATE(R) …

Buspirone

Buspirone is a novel anxiolytic agent with a unique structure and a pharmacological profile. Belonging to the azaspirodecanedione drug class, buspirone is a serotonin 5-HT1A receptor agonist that is not chemically or pharmacologically related to benzodiazepines, barbiturates, and other sedative/anxiolytic drugs. Unlike many drugs used to treat anxiety, buspirone does...
Approved
Investigational
Matched Description: … been used to treat anxiety disorders, such as generalized anxiety disorder (GAD), and relieve symptoms of ... It has also been used as a second-line therapy for unipolar depression when the use of selective serotonin ... [L7375] The potential use of buspirone in combination with [melatonin] in depression and cognitive impairment …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Nafcillin

A semi-synthetic antibiotic related to penicillin, Naficillin is a narrow-spectrum beta-lactam antibiotic drug. It is a beta-lactamase-resistant penicillin that is indicated for the treatment of Staphylococcal infections caused by strains that are resistant to other penicillins, except those caused by MRSA. It may be used as a first-line therapy in...
Approved
Investigational
Matched Description: … It is a beta-lactamase-resistant penicillin that is indicated for the treatment of Staphylococcal infections …
Matched Categories: … combinations of penicillins …

Methyltestosterone

A synthetic anabolic steroid used for treating men with testosterone deficiency or similar androgen replacement therapies. Also, has antineoplastic properties and so has been used secondarily in women with advanced breast cancer. Methyltestosterone is a schedule III drug in the US.
Approved
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Febuxostat

Febuxostat is a non-purine xanthine oxidase (XO) inhibitor. In early 2008, febuxostat was granted marketing authorization by the European Commission for the treatment of chronic hyperuricemia and gout. In the following year, the FDA for approved febuxostat for use in the chronic management of hyperuricemia in adult patients with gout...
Approved
Matched Description: … [L32238] Gout is a form of arthritis that is caused by the accumulation of uric acid crystal in or around ... Febuxostat works by inhibiting the activity of an enzyme that is responsible for the synthesis of uric ... [A230548] In the following year, the FDA for approved febuxostat for use in the chronic management of …

Rubidium Rb-82

Rubidium chloride Rb-82 injection is a sterile nonpyrogenic solutions of rubidium Rb 82 chloride. It is indicated for Positron Emission Tomography (PET) imaging of the myocardium under rest or pharmacologic stress conditions to evaluate regional myocardial perfusion in adult patients with suspected or existing coronary artery disease.
Approved
Investigational
Matched Description: … Rubidium chloride Rb-82 injection is a sterile nonpyrogenic solutions of rubidium Rb 82 chloride. ... It is indicated for Positron Emission Tomography (PET) imaging of the myocardium under rest or pharmacologic …

Ferric maltol

Ferric maltol is an iron(III) atom complexed with 3 maltol molecules to increase the bioavailability compared to iron(II), without depositing it in the duodenum as insoluble ferric hydroxide and phosphate. Ferric maltol has been described in literature since at least the late 1980s as a potential treatment for iron deficiency....
Approved

Padimate O

Padimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in concentrations up to 8%, as regulated by the FDA . It is a structurally-related compound to DB02362 that absorbs UV-B rays to prevent photodamage. It penetrates human skin, and is shown to induce non-ligatable strand...
Approved
Matched Mixtures name: … Sun Lipcare SPF 18 ... Rayito de Sol Sunscreen SPF 18 ... Kiss My Face SPF 18 Lip Balm …

Memantine

Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). It is different from many other Alzheimer's Disease medications, as it works by a different mechanism than the cholinesterase enzyme inhibitors normally employed in the management of Alzheimer's...
Approved
Investigational
Matched Description: … FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of ... a different mechanism than the cholinesterase enzyme inhibitors normally employed in the management of ... Almost doubling every 20 years, the prevalence of Alzheimer's Disease is predicted to reach 66 million …
Matched Products: … MEMDRIVE (R) 10 TABLETAS RECUBIERTAS …

Wormwood

Wormwood is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental

Idarucizumab

Idarucizumab is a humanized monoclonal antibody fragment (Fab) derived from an immunoglobulin G1 isotype molecule that binds to and inactivates the oral anticoagulant dabigatran, thereby reversing its anticoagulant effect. As a direct acting oral anticoagulant (DOAC), one of the risks associated with the use of dabigatran includes bleeding, espeically when...
Approved
Matched Description: … As a direct acting oral anticoagulant (DOAC), one of the risks associated with the use of dabigatran ... Its use is associated with immediate, complete and sustained reversal of the anticoagulant effects of ... Approved under the tradename Praxbind (FDA), idarucizumab is indicated for the emergency treatment of …

Rosuvastatin

Rosuvastatin, also known as the brand name product Crestor, is a lipid-lowering drug that belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver. More specifically, statin medications...
Approved
Matched Description: … studies to significantly reduce the risk of development of CVD and all-cause mortality. ... and for people with a moderate to high risk of development of CVD, such as those with Type 2 Diabetes ... [A181087,A181553] Use of statins to target and reduce LDL levels has been shown in a number of landmark …
Matched Categories: … combinations of sulfonamides …
Matched Products: … KALINEX (R) TABLETASRECUBIERTASX 10 MG …

Pentobarbital

A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA...
Approved
Investigational
Vet approved
Matched Description: … induction than for sedation but, like similar agents, may lose its effectiveness by the second week of …
Matched Categories: … combinations of barbiturates …

Minaprine

Minaprine is a psychotropic drug which has proved to be effective in the treatment of various depressive states. Like most antidepressants minaprine antagonizes behavioral despair. Minaprine is an amino-phenylpyridazine antidepressant reported to be relatively free of cardiotoxicity, drowsiness, and weight gain.
Approved
Matched Description: … Minaprine is a psychotropic drug which has proved to be effective in the treatment of various depressive ... Minaprine is an amino-phenylpyridazine antidepressant reported to be relatively free of cardiotoxicity …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Benzatropine

Benztropine, with the chemical formula 3alpha-diphenylmethoxytropane, is a tropane-based dopamine inhibitor used for the symptomatic treatment of Parkinson's disease. It is a combination molecule between a tropane ring, similar to cocaine, and a diphenyl ether from the dialkylpiperazines determined to be a dopamine uptake inhibitor since 1970. The generation of...
Approved
Matched Description: … of a chlorine substituent in the para position in one of the phenyl rings produces an increased potency ... 3alpha-diphenylmethoxytropane, is a tropane-based dopamine inhibitor used for the symptomatic treatment of ... for dopamine uptake inhibition as well as a decreased inhibition of serotonin and norepinephrine. …
Matched Categories: … Ethers of Tropine or Tropine Derivatives …

Loxapine

An antipsychotic agent used in schizophrenia. [PubChem]
Approved
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Metolazone

A quinazoline-sulfonamide that is considered a thiazide-like diuretic which is long-acting so useful in chronic renal failure. It also tends to lower blood pressure and increase potassium loss.
Approved
Matched Categories: … combinations of sulfonamides …

Linezolid

Linezolid is a synthetic antibiotic which is used for the treatment of infections caused by aerobic Gram-positive bacteria. Its effects are bacteriostatic against both enterococci and staphylococci and bactericidal against most isolates of streptococci. Linezolid exerts its antibacterial activity by inhibiting the initiation of bacterial protein synthesis - more specifically,...
Approved
Investigational
Matched Description: … are bacteriostatic against both enterococci and staphylococci and bactericidal against most isolates of ... [L32965] Linezolid exerts its antibacterial activity by inhibiting the initiation of bacterial protein ... synthesis - more specifically, it binds to the 23S ribosomal RNA of the 50S subunit[A11227,A199050] …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Opium

Opium is the first substance of the diverse group of the opiates. It has been known for a long time, and the first evidence of a poppy culture dates from 5 thousand years by the Sumerians. During the years, opium was used as a sedative and hypnotic, but it was...
Approved
Illicit
Matched Description: … Opium is the first substance of the diverse group of the opiates. ... harmful effects of opium. ... in the category of isoquinolines. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Norgestimate

Norgestimate was first described in the literature in 1977. It was developed by Ortho Pharmaceutical Corporation as part of an effort to develop new hormonal contraceptives with reduced adverse effects. It is commonly formulated with ethinylestradiol as a combined oral contraceptive that can also be used to treat moderate acne...
Approved
Investigational
Matched Description: … [A191068] It was developed by Ortho Pharmaceutical Corporation as part of an effort to develop new hormonal …
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Efmoroctocog alfa

Efmoroctocog alfa is a fully recombinant factor VIII-Fc fusion protein (rFVIIIFc) with an extended half-life compared with conventional factor VIII (FVIII) preparations, including recombinant FVIII (rFVIII) products such as DB13999 . It is an antihemorrhagic agent used in replacement therapy for patients with haemophilia A (congenital factor VIII deficiency). It...
Approved
Investigational
Matched Description: … The B domain of factor VIII is deleted. ... reduced frequency of injections required and improved adherence to prophylaxis [A31551]. ... Prophylactic treatment may dramatically improve the management of severe haemophilia A in the future …

Tazobactam

Tazobactam is an antibiotic of the beta-lactamase inhibitor class that prevents the breakdown of other antibiotics by beta-lactamase enzyme producing organisms. It is combined with Piperacillin and Ceftolozane for the treatment of a variety of bacterial infections. Piperacillin-tazobactam was initially approved by the FDA in 1994, and ceftolozane-tazobactam was approved...
Approved
Matched Description: … Tazobactam is an antibiotic of the beta-lactamase inhibitor class that prevents the breakdown of other ... It is combined with [Piperacillin] and [Ceftolozane] for the treatment of a variety of bacterial infections ... hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia, which are significant causes of …
Displaying drugs 276 - 300 of 9713 in total