Displaying drugs 276 - 300 of 9337 in total
Zolpidem
Zolpidem, also known as Ambien, is a hypnotic drug that was initially approved by the FDA in 1992 [FDA label]. Zolpidem improves sleep in patients with insomnia. It is aimed for use in patients with difficulties initiating sleep. This drug decreases the time to fall asleep (sleep latency), increases the...
Approved
Matched Description: … Zolpidem, also known as _Ambien_, is a hypnotic drug that was initially approved by the FDA in 1992 [ …
Entacapone
Entacapone is a selective, reversible catechol-O-methyl transferase (COMT) inhibitor for the treatment of Parkinson's disease. It is a member of the class of nitrocatechols. When administered concomittantly with levodopa and a decarboxylase inhibitor (e.g., carbidopa), increased and more sustained plasma levodopa concentrations are reached as compared to the administration of...
Approved
Investigational
Hydrogen peroxide
Hydrogen peroxide is the simplest peroxide with a chemical formula H2O2. Hydrogen peroxide is an unstable compound in the presence of a base or catalyst, and is typically stored with a stabilizer in a weakly acidic solution. If heated to its boiling point, it may undergo potentially explosive thermal decomposition....
Approved
Vet approved
Matched Description: … antimicrobial agent in starch and cheese products, and as an oxidizing and reducing agent in products ... It is used in industrial and cosmetic applications as a bleaching agent. ... Hydrogen peroxide is an unstable compound in the presence of a base or catalyst, and is typically stored …
Glasdegib
Glasdegib, also known as PF-04449913, is a small-molecule hedgehog signaling inhibitor selected under the group of benzimidazoles. In early research, benzimidazoles attracted large interest as they represented a class of inhibitors with low molecular weight, potent inhibitory activity, and lacking unstable functionality. The great lipophilicity of this group of compounds...
Approved
Investigational
Matched Description: … [A40310]
Glasdegib was developed by Pfizer Inc and approved on November 21, 2018 by the FDA for the ... Glasdegib, also known as PF-04449913, is a small-molecule hedgehog signaling inhibitor selected under the group ... [A40310] The great lipophilicity of this group of compounds brought interest to further modification. …
Sufentanil
Sufentanil is an opioid analgesic that is used as an adjunct in anesthesia, in balanced anesthesia, and as a primary anesthetic agent. It is administered by the intravenous, epidural and sublingual routes.
Also known as Dsuvia, the sublingual form is used for the management of acute pain in adults that...
Approved
Investigational
Matched Description: … as a primary anesthetic agent. ... (AcelRx), was approved on November 2, 2018 [L4717]. ... Sufentanil is an opioid analgesic that is used as an adjunct in anesthesia, in balanced anesthesia, and …
Moxisylyte
Moxisylyte, denominated as thymoxamine in the UK, is a specific and orally active α1-adrenergic antagonist. According to the WHO, moxisylyte is approved since 1987 and in the same year, it acquired the denomination of orphan product by the FDA. This drug was developed by the Japanese company Fujirebio and also...
Approved
Investigational
Matched Description: … [T45] According to the WHO, moxisylyte is approved since 1987[T91] and in the same year, it acquired …
Biperiden
A muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine.
Approved
Investigational
Brentuximab vedotin
Brentuximab vedotin, also known as Adcetris®, is an antibody-drug conjugate that combines an anti-CD30 antibody with the drug monomethyl auristatin E (MMAE). It is an anti-neoplastic agent used in the treatment of Hodgkin's lymphoma and systemic anaplastic large-cell lymphoma. Brentuximab vedotin was initially approved in 2011. In January 2012, the...
Approved
Investigational
Matched Description: … It is an anti-neoplastic agent used in the treatment of Hodgkin's lymphoma and systemic anaplastic large-cell ... Brentuximab vedotin, also known as Adcetris®, is an antibody-drug conjugate that combines an anti-CD30 ... Brentuximab vedotin was initially approved in 2011. …
Pimavanserin
Pimavanserin is an atypical antipsychotic indicated for the treatment of psychiatric disorders. Although the exact mechanism of action is unknown, it is thought that pimavanserin interacts with the serotonin receptors, particularly the 5-HT2A and HT2C receptors. Unlike other atypical antipsychotics, pimavanserin lacks inherent dopaminergic activity. In fact, pimavanserin is the...
Approved
Investigational
Matched Description: … Pimavanserin is an atypical antipsychotic indicated for the treatment of psychiatric disorders. ... [A232783] It was approved by the FDA in April 2016 for the treatment of hallucinations and delusions ... psychosis thanks to favorable results from a pivotal six-week, randomized, placebo-controlled, parallel-group …
Matched Categories: … Antidepressive Agents …
Matched Categories: … Antidepressive Agents …
Gadoteric acid
Gadoteric acid, commonly used in the salt form gadoterate meglumine, is a macrocyclic, ionic gadolinium-based contrast agent (GBCA). It is composed of the organic acid DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) used for its chelating properties, and gadolinium (Gd3+). Gadoterate meglumine has one of the highest thermodynamic stability, apparent stability, and kinetic stability,...
Approved
Matched Description: … commonly used in the salt form gadoterate meglumine, is a macrocyclic, ionic gadolinium-based contrast agent ... [A263141,A263106]
Gadoterate is approved by the FDA under the brand name DOTAREM on 20th March 2013 …
Matched Categories: … Gadolinium-based Contrast Agent …
Matched Categories: … Gadolinium-based Contrast Agent …
Cevimeline
Cevimeline is a parasympathomimetic agent that act as an agonist at the muscarinic acetylcholine receptors M1 and M3. It is indicated by the Food and Drug Administration for the treatment of dry mouth associated with Sjögren's syndrome.
Approved
Matched Description: … Cevimeline is a parasympathomimetic agent that act as an agonist at the muscarinic acetylcholine receptors …
Raltitrexed
Raltitrexed (brand name Tomudex®) is a chemotherapy drug manufactured AstraZeneca Company, is an antimetabolite used in chemotherapy. It is an inhibitor of thymidylate synthase.
Approved
Investigational
Matched Description: … It is an inhibitor of thymidylate synthase. ... Raltitrexed (brand name Tomudex®) is a chemotherapy drug manufactured AstraZeneca Company, is an …
Panitumumab
Panitumumab (ABX-EGF) is a recombinant human IgG2 monoclonal antibody that binds specifically to the human epidermal growth factor receptor (EGFR). This drug is an antineoplastic agent.
Panitumumab was granted FDA approval on 27 September 2006.
Approved
Investigational
Matched Description: … This drug is an antineoplastic agent.
Panitumumab was granted FDA approval on 27 September 2006. …
Vancomycin
Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear.
As of January 29 2018, CutisPharma's Firvanq is the only FDA approved vancomycin oral liquid treatment option available for the the treatment of...
Approved
Matched Description: … As of January 29 2018, CutisPharma's Firvanq is the only FDA approved vancomycin oral liquid treatment ... Such an oral liquid formulation is expected to make _Clostridium difficile_ associated diarrhea therapy …
Mercaptopurine
An antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.
Approved
Matched Description: … An antimetabolite antineoplastic agent with immunosuppressant properties. …
Erdafitinib
In early April of 2019, the US FDA approved Janssen Pharmaceutical Companies' brand name Balversa (erdafitinib) as the first-ever fibroblast growth factor receptor (FGFR) kinase inhibitor indicated for patients with locally advanced or metastatic urothelial carcinoma, with susceptible FGFR3 or FGFR2 genetic alterations, that has progressed during or following platinum-containing...
Approved
Investigational
Matched Description: … In early April of 2019, the US FDA approved Janssen Pharmaceutical Companies' brand name Balversa (erdafitinib ... [L5956, L5959] At the same time, the FDA also approved the therascreen FGFR RGQ RT-PCR Kit (Qiagen) for …
Pegulicianine
Pegulicianine is an optical imaging agent indicated for fluorescence imaging in patients with breast cancer. It is used following surgical resection of the primary tumor to detect areas of remaining cancer. Pegulicianine itself is a prodrug comprising three main fragments, one of which contains a fluorescence quencher that keeps the...
Approved
Matched Description: … Pegulicianine is an optical imaging agent indicated for fluorescence imaging in patients with breast ... [L50537]
Pegulicianine (under the brand name Lumisight) was approved for use by the FDA in April 2024 …
Dihydrocodeine
Dihydrocodeine is an opioid analgesic used as an alternative or adjunct to codeine to treat moderate to severe pain, severe dyspnea, and cough.
It is semi-synthetic, and was developed in Germany in 1908 during an international search to find a more effective antitussive agent to help reduce the spread of...
Approved
Illicit
Matched Description: … effective antitussive agent to help reduce the spread of airborne infectious diseases such as tuburculosis ... Dihydrocodeine is an opioid analgesic used as an alternative or adjunct to codeine to treat moderate ... It is semi-synthetic, and was developed in Germany in 1908 during an international search to find a more …
Anthrax immune globulin human
Anthrax immune globulin is a human antibody given with antibiotics for the treatment of anthrax. It is derived from the plasma of humans immunized with BioThrax (adsorbed anthrax vaccine), which is then further purified. Available as the product Anthrasil (FDA), the result is a solution for slow IV infusion containing...
Approved
Methylnaltrexone
Methylnaltrexone is a pheriphally-acting μ-opioid antagonist that acts on the gastrointestinal tract to decrease opioid-induced constipation without producing analgesic effects or withdrawal symptoms. It is also a weak CYP2D6 inhibitor. FDA approved in 2008.
Approved
Matched Description: … FDA approved in 2008. …
Aluminum zirconium pentachlorohydrate
Aluminum zirconium pentachlorohydrate is a common active ingredient in personal care products as an antiperspirant agent. Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing sweat from leaving the body.
Approved
Matched Description: … agent. ... Aluminum zirconium pentachlorohydrate is a common active ingredient in personal care products as an antiperspirant …
Levodopa
Levodopa is a prodrug of dopamine that is administered to patients with Parkinson's due to its ability to cross the blood-brain barrier[Label]. Levodopa can be metabolised to dopamine on either side of the blood-brain barrier and so it is generally administered with a dopa decarboxylase inhibitor like carbidopa to prevent...
Approved
Matched Description: … called Sinemet that was approved on May 2, 1975[A177781,L6133]. ... The first developed drug product that was approved by the FDA was a levodopa and carbidopa combined product …
Levonorgestrel
Levonorgestrel (LNG) is a synthetic progestogen similar to Progesterone used in contraception and hormone therapy.[A181988,T659] Also known as Plan B, it is used as a single agent in emergency contraception, and as a hormonal contraceptive released from an intrauterine device, commonly referred to as an IUD. Some of these devices...
Approved
Investigational
Matched Description: … a hormonal contraceptive released from an intrauterine device, commonly referred to as an IUD. ... [A181988,T659] Also known as Plan B, it is used as a single agent in emergency contraception, and as …
Brodalumab
Brodalumab has been used in trials studying the treatment of Asthma, Psoriasis, Crohn's Disease, Psoriatic Arthritis, and Rheumatoid Arthritis. Brodalumab was FDA approved in February, 2017 as Siliq for the treatment of moderate-to-severe plaque psoriasis.
Approved
Investigational
Matched Description: … Brodalumab was FDA approved in February, 2017 as Siliq for the treatment of moderate-to-severe plaque …
Dexrazoxane
An antimitotic agent with immunosuppressive properties. Dexrazoxane, the (+)-enantiomorph of razoxane, provides cardioprotection against anthracycline toxicity. It appears to inhibit formation of a toxic iron-anthracycline complex. [PubChem]
The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the prevention or reduction in the incidence and...
Approved
Withdrawn
Matched Description: … An antimitotic agent with immunosuppressive properties. ... [PubChem]
The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the …
Matched Categories: … Cytoprotective Agent …
Matched Categories: … Cytoprotective Agent …
Displaying drugs 276 - 300 of 9337 in total