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Displaying drugs 276 - 300 of 15732 in total

Satralizumab

Satralizumab is a recombinant humanized monoclonal antibody targeted against human interleukin-6 (IL-6) receptors, similar to tocilizumab, which is produced in Chinese hamster ovary cells and based on an IgG2 framework. Satralizumab is used in the treatment of neuromyelitis optica spectrum disorder (NMOSD), a rare autoimmune inflammatory disorder of the central...
Approved
Matched Description: … [A218551] It received subsequent approvals in Switzerland and Japan,[A218551] and was approved for use ... interleukin-6 (IL-6) receptors, similar to [tocilizumab], which is produced in Chinese hamster ovary cells and ... at least in part, by IL-6, including increased production of anti-aquaporin-4 (AQP4) autoantibodies and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …

Padimate O

Padimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in concentrations up to 8%, as regulated by the FDA . It is a structurally-related compound to DB02362 that absorbs UV-B rays to prevent photodamage. It penetrates human skin, and is shown to induce non-ligatable strand...
Approved
Matched Description: … It penetrates human skin, and is shown to induce non-ligatable strand breaks on DNA _in vitro_ and mutagenic ... Padimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in …
Matched Mixtures name: … Sun and Ski Stick SPF 15 ... Aruba Aloe Lip Sunscreen and Moisturizer ... Phineas and Ferb Sun Smacker SPF 24 Berry Busted …
Matched Products: … Hand and Body Lotion SPF 15 ... Green Tea and Ginkgo Moisturizer SPF 10 …

Capsicum oleoresin

Capsicum oleoresin is an oily organic resin derived from the fruit of plants in the Capsicum genus, such as chilli peppers. When the plants are finely ground, capsicum oleoresin is formed after the extraction process of capsaicin using oragnic solvents such as ethanol. It is commonly used as a culinary...
Approved
Matched Description: … pains of muscles and joints as an active ingredient in topical OTC preparations and has been studied ... , nordihydrocapsaicin, homocapsaicin, and homodihydrocapsaicin [A32318]. ... [DB06774] and dihydrocapsaicin are the most pungent capsaicinoid analogues [A32318]. …
Matched Mixtures name: … Half and Half Balm ... Hot Spice and Ice …
Matched Products: … Sheffield Arthritis and Muscle Pain Relief …

Plecanatide

Plecanatide is a drug approved in January 2017 by the FDA for the treatment of chronic idiopathic constipation (CIC). It should not be used in children less than six years of age, and should be avoided in patients six years to 18 years of age
Approved
Investigational
Matched Iupac: … }butanoic acid ... -32-[(1R)-1-hydroxyethyl]-4-methyl-19-(2-methylpropyl)-7,13-bis(propan-2-yl)-27,28,40,41-tetrathia-2,5,8,11,14,17,20,23,31,34,37 ... }-22-(2-carboxyethyl)-3,6,9,12,15,18,21,24,30,33,36-undecahydroxy-10-[(C-hydroxycarbonimidoyl)methyl] ... (4S)-4-{[(2S)-2-{[(2S)-2-amino-1-hydroxy-3-(C-hydroxycarbonimidoyl)propylidene]amino}-3-carboxy-1-hydroxypropylidene ... ]amino}-4-{[(1R,4S,7S,10S,13S,16R,19S,22S,25R,32S,38R)-38-{[(1S)-1-carboxy-3-methylbutyl]-C-hydroxycarbonimidoyl …
Matched Description: … It should not be used in children less than six years of age, and should be avoided in patients six years …
Matched Categories: … Guanylate Cyclase-C Agonist ... Guanylyl Cyclase C Agonists ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Ambrosia artemisiifolia pollen

Ambrosia artemisiifolia pollen is the pollen of the Ambrosia artemisiifolia plant. Ambrosia artemisiifolia pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … Short and Giant Ragweed Pollen Mix ... Pollens - Weeds and Garden Plants, Ragweed, Mixed Ambrosia ... Pollens - Weeds and Garden Plants, Ragweed, Mixed Ambrosia …
Matched Products: … Pollens - Weeds and Garden Plants, Short Ragweed, Ambrosia artemisiifolia …

Polyethylene glycol 400

Polyethylene glycols (PEGs) are products made of condensed ethylene oxide and water that can contain various derivatives and have various functions. Because many PEG types are hydrophilic, they are favorably used as enhancers of penetration, and used heavily in topical dermatological preparations. PEGs, along with their many nonionic derivatives, are...
Approved
Matched Description: … various derivatives and have various functions. ... Polyethylene glycols (PEGs) are products made of condensed ethylene oxide and water that can contain ... Examples of PEGylated medications are PEG-interferon alpha (Pegintron) and PEG-filgrastim. …
Matched Mixtures name: … Redness reliever and Lubricant ... Systane Day and Night Value Pack ... Systane Day and Night Value Pack …
Matched Products: … Foster and Thrive Dry Eye Relief …

Dactinomycin

A compound composed of a two cyclic peptides attached to a phenoxazine that is derived from streptomyces parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin...
Approved
Investigational
Matched Synonyms: … DILACTONE ACTINOMYCIN D ACID …
Matched Description: … It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than …
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …

Pepsin

Pepsin is a potent enzyme in gastric juice that digests proteins such as those in meat, eggs, seeds, and dairy products . Studies on gastric digestion from 1820-1840 led to the discovery of pepsin as the substance which, in the presence of stomach acid, causes nutrients including meat or coagulated...
Approved
Experimental
Investigational
Matched Description: … digestion from 1820-1840 led to the discovery of pepsin as the substance which, in the presence of stomach acid ... Stimulation of the pancreas and therefore enzymatic digestion of food is a tightly controlled and is ... Pepsin is a potent enzyme in gastric juice that digests proteins such as those in meat, eggs, seeds, and …
Matched Mixtures name: … Glutamic Acid Pepsin and Betaine Tablets ... Betaine HCl and Pepsin ... Glutamic Acid Hydrochloride Nu Life …
Matched Categories: … pepsin and acid preparations ... Aspartic Acid Proteases ... Enzymes and Coenzymes ... Aspartic Acid Endopeptidases ... Alimentary Tract and Metabolism …

Hydrochlorothiazide

Hydrochlorothiazide is the most commonly prescribed thiazide diuretic. It is indicated to treat edema and hypertension.[A185138,L8447,L8450] Hydrochlorothiazide use is common but declining in favour of angiotensin converting enzyme inhibitors. Many combination products are available containing hydrochlorothiazide and angiotensin converting enzyme inhibitors[L8390,L8423] or angiotensin II receptor blockers.[L7426,L7459] Hydrochlorothiazide was granted FDA...
Approved
Vet approved
Matched Description: … [A185138] It is indicated to treat edema and hypertension. ... [A185138] Many combination products are available containing hydrochlorothiazide and angiotensin converting …
Matched Mixtures name: … CANDESARTAN ABZ C 32/25 ... CANDESARTAN RAT C 32/25 ... CANDESARTAN RAT C 32/25 …
Matched Categories: … hydrochlorothiazide and potassium ... aliskiren and hydrochlorothiazide ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... ramipril, amlodipine and hydrochlorothiazide …
Matched Products: … Losartan Potassium and Hydrochlorothiazide …

Azithromycin

Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue penetration . It was initially approved by the FDA in 1991 . It is primarily used for the treatment of respiratory, enteric and genitourinary infections and may be used instead of other macrolides for...
Approved
Matched Description: … March 2020, a small study was funded by the French government to investigate the treatment of COVID-19 ... It is primarily used for the treatment of respiratory, enteric and genitourinary infections and may be ... used instead of other macrolides for some sexually transmitted and enteric infections. …
Matched Salts cas: … 554432-19-8 …
Matched Salts name: … Azithromycin monohydrate ... Azithromycin hemiethanolate monohydrate …
Matched Categories: … Experimental Unapproved Treatments for COVID-19 ... cefixime and azithromycin ... azithromycin, fluconazole and secnidazole ... Macrolides, Lincosamides and Streptogramins …
Matched Products: … GLED' C ZIT ... Azithromycin Monohydrate ... Azithromycin monohydrate …

Sotrovimab

Sotrovimab (VIR-7831), also known as GSK4182136, is a monoclonal antibody that can neutralize the SARS-CoV-2 virus. Sotrovimab was initially been granted emergency use authorization (EUA) to treat mild-to-moderate COVID-19 on May 26, 2021, based on interim results from a clinical trial, where sotrovimab was found to reduce the risk of...
Approved
Investigational
Matched Description: … sotrovimab was found to reduce the risk of death or hospitalization in high-risk adults with COVID-19 ... Sotrovimab was initially been granted emergency use authorization (EUA) to treat mild-to-moderate COVID-19 ... L34430, L34440] However, in April 2022, the FDA removed the EUA for sotrovimab due to the rising COVID-19 …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Approved Treatments for COVID-19 ... Immune Sera and Immunoglobulins ... Experimental Unapproved Treatments for COVID-19 …

Lucinactant

Lucinactant is a new synthetic peptide-containing surfactant for intratracheal use. It contains sinapultide, a novel, hydrophobic, 21-amino acid peptide (leucine and lysine repeating units, KL4 peptide) designed to mimic human surfactant protein-B (SB-P). More specifically, it mimics the C-terminal amphipathic helical domain of this protein. It also consists of phospholipids...
Approved
Investigational
Matched Description: … , POPG) and a fatty acid (palmitic acid). ... It contains sinapultide, a novel, hydrophobic, 21-amino acid peptide (leucine and lysine repeating units ... More specifically, it mimics the C-terminal amphipathic helical domain of this protein. …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Dalfampridine

Dalfampridine is a potassium channel blocker used to help multiple sclerosis patients walk. This is the first drug that was specifically approved to help with mobility in these patients. FDA approved on January 22, 2010.
Approved

Zinc gluconate

Zinc gluconate is a zinc salt of gluconic acid comprised of two gluconic acid molecules for each zinc cation (2+). Zinc gluconate is a generally recognized as safe (GRAS) substance by FDA . It is available as a trace mineral supplement and over the counter as a lozenge form for...
Approved
Vet approved
Matched Description: … Zinc gluconate is a zinc salt of gluconic acid comprised of two gluconic acid molecules for each zinc ... of common colds and with decreased symptom severity. ... It is available as a trace mineral supplement and over the counter as a lozenge form for a reduced duration …
Matched Salts cas: … 12389-19-4 …
Matched Mixtures name: … Cal-mag Vitamin C and Zinc Tab ... AVi VITAMIN C 1000 mg with Zinc, Real Ginger, Honey, Lemon and Lemongrass ... C 106 Tab …
Matched Categories: … Alimentary Tract and Metabolism ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …

Insulin aspart

Insulin aspart is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … with aspartic acid. ... Compared to human insulin, it has a single amino acid substitution at position B28 where proline is replaced ... and proteolysis among many other functions. …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin degludec and insulin aspart ... Insulins and Analogues for Injection, Fast-Acting ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … .Insulin Aspart Protamine and Insulin Aspart ... Insulin Aspart Protamine and Insulin Aspart Mix 70/30 …

Betaine

Betaine is a methyl group donor that functions in the normal metabolic cycle of methionine. It is a naturally occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and maintaining cell function.[A252235,A252240] Homocystinuria is an inherited disorder that leads to the accumulation of homocysteine in...
Approved
Investigational
Nutraceutical
Matched Description: … occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and ... levels, patients can be treated with vitamin B6 ([pyridoxine]), vitamin B12 ([cobalamin]), [folate] and ... The FDA and EMA have approved the product Cystadane (betaine anhydrous, oral solution) for the treatment …
Matched Mixtures name: … Glutamic Acid Pepsin and Betaine Tablets ... Glutamic Acid HCl Betaine HCl W Pepsin ... Betaine HCl and Pepsin …
Matched Categories: … Acid Preparations ... Amino Acids and Derivatives ... Alimentary Tract and Metabolism …

Hydrocortisone acetate

Approved
Vet approved
Matched Mixtures name: … ZISUAL-C ... HYDRODERM-C CREAM 1% ... Neomycin and Polymyxin B Sulfates and Bacitracin Zinc with Hydrocortisone Acetate …
Matched Categories: … Hydrocortisone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … American Safety and First Aid …

Flavin mononucleotide

A coenzyme for a number of oxidative enzymes including NADH DEHYDROGENASE. It is the principal form in which RIBOFLAVIN is found in cells and tissues.
Approved
Investigational
Matched Iupac: … -{7,8-dimethyl-2,4-dioxo-2H,3H,4H,10H-benzo[g]pteridin-10-yl}-2,3,4-trihydroxypentyl]oxy}phosphonic acid …
Matched Description: … It is the principal form in which RIBOFLAVIN is found in cells and tissues. …
Matched Mixtures name: … Somarexin and C 1000 ... B Complex W C and B12 Inj ... Supravite C 1000 …
Matched Categories: … Enzymes and Coenzymes ... Nucleic Acids, Nucleotides, and Nucleosides …

SARS-CoV-2 virus recombinant spike (S) protein receptor binding domain (RBD) fusion heterodimer (B.1.351-B.1.1.7 strains)

Bimervax is an adjuvanted non-mRNA COVID-19 vaccine utilizing a SARS-CoV-2 recombinant spike (S) protein receptor binding domain (RBD) fusion heterodimer. It is intended to elicit protection against Omicron XBB.1.5, one of the dominant circulating SARS-CoV-2 subvariants in 2023. It is produced using recombinant DNA technology in CHO cell lines and...
Approved
Matched Description: … [A262551] It is produced using recombinant DNA technology in CHO cell lines and is marketed by Hipra ... Bimervax is an adjuvanted non-mRNA COVID-19 vaccine utilizing a SARS-CoV-2 recombinant spike (S) protein ... the EU in March 2023 for use as a booster dose in patients who have previously received an mRNA COVID-19 …
Matched Categories: … COVID-19 Vaccines …

Leuprolide

Leuprolide is a synthetic 9-residue peptide analogue of gonadotropin-releasing hormone (GnRH). Unlike the endogenous decapeptide GnRH, leuprolide contains a single D-amino acid (D-leucyl) residue, which helps to increase its circulating half-life from three to four minutes to approximately three hours. As a GnRH mimic, leuprolide is capable of binding to...
Approved
Investigational
Matched Description: … Unlike the endogenous decapeptide GnRH, leuprolide contains a single D-amino acid (D-leucyl) residue, ... downstream modulation of both gonadotropin hormone and sex steroid levels. ... [A203222] As a GnRH mimic, leuprolide is capable of binding to the GnRH receptor (GnRHR) and inducing …
Matched Categories: … Hormones and Related Agents ... Amino Acids, Peptides, and Proteins ... leuprorelin and bicalutamide ... Antineoplastic and Immunomodulating Agents …
Matched Products: … POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 45mg ... POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 7.5mg ... POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 22.5mg …

Tioconazole

Tioconazole is an imidazole antifungal used to treat fungal and yeast infections. Topical formulations are used for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus". Tioconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the yeast membrane. In...
Approved
Matched Description: … Tioconazole is an imidazole antifungal used to treat fungal and yeast infections. ... Topical formulations are used for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus …
Matched Categories: … Imidazole and Triazole Derivatives ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Metabolic Side Effects of Drugs and Substances ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Up and up tioconazole 1 ... Foster and Thrive Tioconazole …

Aluminum hydroxide

Aluminum hydroxide is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. Subsequent increases in pH may inhibit the action of pepsin. An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects.
Approved
Investigational
Matched Description: … It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. ... An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects. …
Matched Mixtures name: … Mi Acid ... Mi Acid ... Mi Acid …
Matched Categories: … Carbonic Acid ... Antacids and Adsorbents ... Alimentary Tract and Metabolism ... Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders …

Indium In-111 pentetreotide

Indium In 111 pentetreotide (Octreoscan) has been used in trials studying the diagnostic of SARCOIDOSIS, Solid Tumors, and cushing syndrome.
Approved
Investigational
Matched Iupac: … -13-[(1H-indol-3-yl)methyl]-9-oxido-1,2-dithia-5,8,11,14,17-pentaazacycloicosa-5,8,11,14,17-pentaen-19 ... -yl]-C-hydroxycarbonimidoyl}-2-phenylethyl)-C-hydroxycarbonimidoyl]methyl}(carboxymethyl)amino)ethyl] ... (111In)indium(3+) ion 2-{[2-({[(1-{[10-(4-aminobutyl)-16-benzyl-4-[(1,3-dihydroxybutan-2-yl)-C-hydroxycarbonimidoyl …
Matched Description: … pentetreotide (Octreoscan) has been used in trials studying the diagnostic of SARCOIDOSIS, Solid Tumors, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Methylcellulose

Methyl cellulose polymer consisting of numerous linked glucose molecules used as a stabiliser, thickener and emulsifier for foodstuffs and cosmetics. The Degree of Substitution (DS) of a given form of methyl cellulose is defined as the average number of substituted hydroxyl groups per glucose with a theoretical maximum of 3,...
Approved
Matched Description: … emulsifier for foodstuffs and cosmetics. ... Like cellulose, it is not digestible, not toxic, and not allergenic ... Methyl cellulose polymer consisting of numerous linked glucose molecules used as a stabiliser, thickener and …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Foster and Thrive Fiber Laxative 188 …

Nilutamide

Nilutamide is an antineoplastic hormonal agent primarily used in the treatment of prostate cancer. Nilutamide is a pure, nonsteroidal anti-androgen with affinity for androgen receptors (but not for progestogen, estrogen, or glucocorticoid receptors). Consequently, Nilutamide blocks the action of androgens of adrenal and testicular origin that stimulate the growth of...
Approved
Investigational
Matched Description: … the growth of normal and malignant prostatic tissue. ... Consequently, Nilutamide blocks the action of androgens of adrenal and testicular origin that stimulate ... Prostate cancer is mostly androgen-dependent and can be treated with surgical or chemical castration. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Displaying drugs 276 - 300 of 15732 in total