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Displaying drugs 3051 - 3075 of 3158 in total
Difloxacin is a synthetic fluoroquinolone used in veterinary. As an antibacterial, it presents a broad bactericidal spectrum and its effects are dependent on its concentration. However, it presents a reduced efficacy when compared to other fluoroquinolone antibacterials.
Vet approved
Matched Categories: … Anti-Bacterial Agents …
Experimental
Matched Categories: … Anti-Bacterial Agents …
Experimental
Matched Categories: … Anti-Inflammatory Agents …
Experimental
Matched Categories: … Anti-Infective Agents …
Oleoyl-estrone (OE) is a fatty acid ester of estrone. This hormone occurs naturally and is found circulating in various animal species and humans. It has been shown in animal studies to promote the loss of body fat while maintaining body protein storage, maintaining nitrogen balance. Body protein loss is an...
Investigational
Matched Categories: … Anti-Obesity Agents …
Tarenflurbil is an investigational drug that was studied in patients with mild Alzheimer's disease. It is a selective amyloid lowering agent (SALA) that reduces levels of the toxic peptide amyloid beta 42 (Aβ42) in cultured human cells and in animal models. Aβ42 is the primary initiator of neurotoxicity and amyloid...
Investigational
Matched Categories: … Anti-Inflammatory Agents …
Laninamivir has been used in trials studying the treatment of Influenza.
Investigational
Matched Categories: … Anti-Infective Agents …
Anisodamine has been investigated for the treatment of Intestinal Diseases.
Investigational
Matched Categories: … Anti-Ulcer Agents ... Anti-Inflammatory Agents …
Gefarnate has been investigated for the treatment and prevention of Stomach Ulcer, Duodenal Ulcer, and Cardio-cerebrovascular Disease.
Investigational
Matched Categories: … Anti-Ulcer Agents …
Inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease, is typified by a chronic gastrointestinal inflammatory microenvironment, driven in part by the excessive infiltration and retention of intestinal-homing lymphocytes.[A244564, A244569, A244579, A244584] A recent class of drugs designed to impair lymphocyte homing, so-called "anti-trafficking agents" (ATAs), have shown some...
Investigational
Matched Description: … A244569, A244579, A244584] A recent class of drugs designed to impair lymphocyte homing, so-called "anti-trafficking …
Superoxide is a natural byproduct of oxygen metabolism which, if left unchecked, leads to cell damage. Superoxide dismutase (SOD) is an enzyme that alternately catalyzes the dismutation of the superoxide radical into either the less damaging hydrogen peroxide or molecular oxygen. Hydrogen peroxide can be degraded by catalase. The antioxidant...
Investigational
Vet approved
Matched Categories: … Anti-Inflammatory Agents …
Experimental
Matched Categories: … Anti-Ulcer Agents …
Galidesivir is an adenosine analogue that has been investigated for use against Zaire Ebolavirus. In animal studies, galidesivir was effective in increasing the survival rates from infections caused by various pathogens, including Ebola, Marburg, Yellow Fever and Zika viruses. In vitro, it displayed broad-spectrum antiviral activity against various negative- and...
Investigational
Matched Categories: … Anti-Infective Agents …
Vesnarinone has been used in trials studying the treatment of HIV Infections and Sarcoma, Kaposi.
Investigational
Matched Categories: … Anti-Infective Agents …
Epofolate has been used in trials studying the treatment of Advanced Solid Tumors. Epofolate (BMS-753493) is a folate conjugate of the epothilone analog BMS-748285 that was designed to selectively target folate receptor expressing cancer cells. In Phase I/IIa pharmacokinetic and safety studies epofolate was generally tolerable and toxicities known to...
Investigational
Matched Categories: … Anti-Bacterial Agents …
Hypericin is under investigation for the treatment of Cutaneous T-cell Lymphoma.
Investigational
Matched Categories: … Anti-Infective Agents …
Experimental
Matched Categories: … Anti-Infective Agents …
Lactoferrin is under investigation in clinical trial NCT03748043 (The Effectiveness of Lactoferrin in Treatment of Iron Deficiency Anemia in Children With Chronic Tonsillitis).
Investigational
Matched Categories: … Anti-Infective Agents …
Experimental
Matched Categories: … Anti-Infective Agents …
An adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. (From Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1437)
Experimental
Matched Categories: … Anti-Inflammatory Agents …
Investigational
Matched Categories: … Anti-Infective Agents …
A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties. Suramin...
Investigational
Matched Categories: … Anti-Infective Agents …
Methapyrilene, formerly marketed in many drug products, was shown to be a potent carcinogen. Manufacturers voluntarily withdrew methapyriline drug products from the market in May and June 1979.
Withdrawn
Matched Categories: … Anti-Allergic Agents …
Orbifloxacin is a fluoroquinolone antibiotic. It is marketed by Schering-Plough Animal Health and approved for certain infections in dogs.
Vet approved
Matched Categories: … Anti-Bacterial Agents …
Sarafloxacin is a quinolone antibiotic drug, which was discontinued by its manufacturer, Abbott Laboratories, before receiving approval for use in the US or Canada.
Vet approved
Withdrawn
Matched Categories: … Anti-Bacterial Agents …
Displaying drugs 3051 - 3075 of 3158 in total