Displaying drugs 3101 - 3125 of 4014 in total
Betaxolol
A cardioselective beta-1-adrenergic antagonist with no partial agonist activity.
Approved
Investigational
Matched Salts name: … Betaxolol hydrochloride …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Products: … Betaxolol Hydrochloride …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Products: … Betaxolol Hydrochloride …
Acebutolol
A cardioselective beta-adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic action.
Approved
Investigational
Matched Description: … The drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic …
Matched Salts name: … Acebutolol hydrochloride …
Matched Categories: … Beta Blocking Agents and Thiazides ... acebutolol and thiazides ... Beta Blocking Agents, Selective, and Thiazides …
Matched Products: … Acebutolol Hydrochloride …
Matched Salts name: … Acebutolol hydrochloride …
Matched Categories: … Beta Blocking Agents and Thiazides ... acebutolol and thiazides ... Beta Blocking Agents, Selective, and Thiazides …
Matched Products: … Acebutolol Hydrochloride …
Cannabinol
Cannabinol (CBN) is a physiologically inactive constituent of Cannabis sativa.
Experimental
Investigational
Matched Synonyms: … 6,6,9-Trimethyl-3-pentyl-6H-dibenzo(b,d)pyran-1-ol …
Matched Categories: … Cannabinoids and similars …
Matched Categories: … Cannabinoids and similars …
5-Nitroso-6-ribityl-amino-2,4(1H,3H)-pyrimidinedione
Experimental
Matched Synonyms: … 1-Deoxy-1-[(5-nitroso-2,6-dioxo-1,2,3,6-tetrahydro-4-pyrimidinyl)amino]-D-ribitol …
Morphine glucuronide
Investigational
Matched Synonyms: … Morphine 6-beta-D-glucopyranosiduronide …
Matched Iupac: … azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10,15-tetraen-14-yl]oxy}oxane-2-carboxylic acid …
Matched Iupac: … azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10,15-tetraen-14-yl]oxy}oxane-2-carboxylic acid …
Racemetyrosine
Racemetyrosine is under investigation in clinical trial NCT03512756 (A Randomized Phase 2/3 Multi-center Study of SM-88 in Patients With Metastatic Pancreatic Cancer).
Investigational
Matched Synonyms: … DL-metyrosine ... D,L-metyrosine …
Matched Iupac: … 2-amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Matched Iupac: … 2-amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Dihydrouridine
Investigational
Matched Synonyms: … -d-ribofuranosyl- ... -d-ribofuranosyl- …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Maprotiline
Maprotiline is a tetracyclic antidepressant with similar pharmacological properties to tricyclic antidepressants (TCAs). Similar to TCAs, maprotiline inhibits neuronal norepinephrine reuptake, possesses some anticholinergic activity, and does not affect monoamine oxidase activity. It differs from TCAs in that it does not appear to block serotonin reuptake. Maprotiline may be used...
Approved
Investigational
Matched Description: … does not affect monoamine oxidase activity. ... TCAs, maprotiline inhibits neuronal norepinephrine reuptake, possesses some anticholinergic activity, and ... be used to treat depressive affective disorders, including dysthymic disorder (depressive neurosis) and …
Matched Salts name: … Maprotiline hydrochloride …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors …
Matched Products: … Maprotiline Hydrochloride …
Matched Salts name: … Maprotiline hydrochloride …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors …
Matched Products: … Maprotiline Hydrochloride …
Naphazoline
Naphazoline is a rapid acting imidazoline sympathomimetic vasoconstrictor of ocular or nasal artierioles[L5804,L5807]. It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations[L5804,L5807].
Naphazoline was first developed in 1942 as a nasal formulation for congestion .
Approved
Investigational
Matched Description: … It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations …
Matched Mixtures name: … Naphazoline Hydrochloride and Pheniramine Maleate ... Naphazoline Hydrochloride and Pheniramine Maleate ... Naphazoline Hydrochloride and Pheniramine Maleate …
Matched Salts name: … Naphazoline hydrochloride …
Matched Categories: … Decongestants and Antiallergics ... Adrenergic alpha-Agonists ... Adrenergic alpha-1 Receptor Agonists ... Adrenergic alpha-2 Receptor Agonists …
Matched Products: … Naphazoline Hydrochloride ... IRIDINA DUE ... Clear Eyes By Murine Eye Dps …
Matched Mixtures name: … Naphazoline Hydrochloride and Pheniramine Maleate ... Naphazoline Hydrochloride and Pheniramine Maleate ... Naphazoline Hydrochloride and Pheniramine Maleate …
Matched Salts name: … Naphazoline hydrochloride …
Matched Categories: … Decongestants and Antiallergics ... Adrenergic alpha-Agonists ... Adrenergic alpha-1 Receptor Agonists ... Adrenergic alpha-2 Receptor Agonists …
Matched Products: … Naphazoline Hydrochloride ... IRIDINA DUE ... Clear Eyes By Murine Eye Dps …
Floxuridine
An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection. Floxuridine is available as a sterile, nonpyrogenic, lyophilized powder for reconstitution. When administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for...
Approved
Matched Synonyms: … 1-beta-D-2'-Deoxyribofuranosyl-5-flurouracil ... 1-(2-Deoxy-beta-D-ribofuranosyl)-5-fluorouracil ... 1beta-D-2'-Deoxyribofuranosyl-5-flurouracil …
Matched Description: … malignant neoplasms of the liver and gastrointestinal tract. ... It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Antineoplastic and Immunomodulating Agents …
Matched Description: … malignant neoplasms of the liver and gastrointestinal tract. ... It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Antineoplastic and Immunomodulating Agents …
Flavoxate
A drug that has been used in various urinary syndromes and as an antispasmodic. Its therapeutic usefulness and its mechanism of action are not clear. It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity as a muscarinic antagonist. [PubChem]
Approved
Matched Description: … A drug that has been used in various urinary syndromes and as an antispasmodic. ... Its therapeutic usefulness and its mechanism of action are not clear. ... It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity …
Matched Salts name: … Flavoxate hydrochloride …
Matched Categories: … Drugs for Urinary Frequency and Incontinence ... Genito Urinary System and Sex Hormones …
Matched Products: … Flavoxate Hydrochloride …
Matched Salts name: … Flavoxate hydrochloride …
Matched Categories: … Drugs for Urinary Frequency and Incontinence ... Genito Urinary System and Sex Hormones …
Matched Products: … Flavoxate Hydrochloride …
(2Z,3E)-2,3'-biindole-2',3(1H,1'H)-dione 3-{O-[(3R)-3,4-dihydroxybutyl]oxime}
Experimental
Matched Name: … (2Z,3E)-2,3'-biindole-2',3(1H,1'H)-dione 3-{O-[(3R)-3,4-dihydroxybutyl]oxime} …
Isoflurophate
An irreversible cholinesterase inhibitor with actions similar to those of echothiophate. It is a powerful miotic used mainly in the treatment of glaucoma. Its vapor is highly toxic and it is recommended that only solutions in arachis oil be used therapeutically. (From Martindale, The Extra Pharmacopoeia, 29th ed, p1330)
Approved
Investigational
Withdrawn
Matched Synonyms: … DFP ... Diisopropylfluorophosphoric acid ester …
Matched Description: … Its vapor is highly toxic and it is recommended that only solutions in arachis oil be used therapeutically …
Matched Description: … Its vapor is highly toxic and it is recommended that only solutions in arachis oil be used therapeutically …
Azlocillin
Azlocillin is a semisynthetic ampicillin-derived acylureido penicillin.
Approved
Matched Synonyms: … oxoimidazolidin-1-yl)carbonyl]amino}-2-phenylacetyl]amino}-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Iupac: … oxoimidazolidine-1-carbonyl)amino]-2-phenylacetamido]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Salts name: … Azlocillin sodium …
Matched Iupac: … oxoimidazolidine-1-carbonyl)amino]-2-phenylacetamido]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Salts name: … Azlocillin sodium …
Symmetric dimethylarginine
Experimental
Matched Synonyms: … (S)-2-amino-5-(N',N''-dimethylguanidino)pentanoic acid …
Matched Iupac: … (2S)-2-amino-5-[(Z)-N',N''-dimethylcarbamimidamido]pentanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino …
Matched Iupac: … (2S)-2-amino-5-[(Z)-N',N''-dimethylcarbamimidamido]pentanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino …
N-Acetylmethionine
Experimental
Matched Synonyms: … (2S)-2-acetamido-4-(methylsulfanyl)butanoic acid …
Matched Iupac: … (2S)-2-acetamido-4-(methylsulfanyl)butanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Neutral ... Amino Acids, Sulfur …
Matched Iupac: … (2S)-2-acetamido-4-(methylsulfanyl)butanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Neutral ... Amino Acids, Sulfur …
Carbocisteine
Dyspnea and cough are common symptoms of chronic obstructive pulmonary disease (COPD) and other respiratory conditions characterized by increased mucus production. Individuals with COPD have a greater risk of pulmonary infection due to the growth and accumulation of viruses and bacteria in thick bronchial mucus. Carbocisteine is a mucolytic drug...
Approved
Investigational
Matched Synonyms: … (L)-2-Amino-3-(carboxymethylthio)propionic acid …
Matched Iupac: … (2R)-2-amino-3-[(carboxymethyl)sulfanyl]propanoic acid …
Matched Description: … Individuals with COPD have a greater risk of pulmonary infection due to the growth and accumulation of ... Dyspnea and cough are common symptoms of chronic obstructive pulmonary disease (COPD)[A231169] and other ... viruses and bacteria in thick bronchial mucus. …
Matched Mixtures name: … GUAYACOLATO DE GLICERILO - CARBOXIMETILCISTEINA …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cough and Cold Preparations ... Amino Acids ... Amino Acids, Neutral ... Amino Acids, Sulfur …
Matched Products: … SOLVELIN DE ANGELI ... CARBOCISTEINA DOC GENERICI …
Matched Iupac: … (2R)-2-amino-3-[(carboxymethyl)sulfanyl]propanoic acid …
Matched Description: … Individuals with COPD have a greater risk of pulmonary infection due to the growth and accumulation of ... Dyspnea and cough are common symptoms of chronic obstructive pulmonary disease (COPD)[A231169] and other ... viruses and bacteria in thick bronchial mucus. …
Matched Mixtures name: … GUAYACOLATO DE GLICERILO - CARBOXIMETILCISTEINA …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cough and Cold Preparations ... Amino Acids ... Amino Acids, Neutral ... Amino Acids, Sulfur …
Matched Products: … SOLVELIN DE ANGELI ... CARBOCISTEINA DOC GENERICI …
INCB-086550
INCB-086550 is under investigation in clinical trial NCT04629339 (Study of INCB086550 in Select Solid Tumors).
Investigational
Matched Synonyms: … 3-PYRROLIDINECARBOXYLIC ACID, 1-((7-CYANO-2-(3'-((3-(((3R)-3-HYDROXY-1-PYRROLIDINYL)METHYL)-1,7-NAPHTHYRIDIN …
Bortezomib
Bortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma and mantle cell lymphoma. The 26S proteasome is a protein complex that degrades ubiquitinated proteins in the ubiquitin-proteasome pathway: reversible inhibition of the 26S proteasome, leading to cell cycle arrest and apoptosis of cancer cells,...
Approved
Investigational
Matched Synonyms: … [(1R)-3-methyl-1-({(2S)-3-phenyl-2-[(pyrazin-2-ylcarbonyl)amino]propanoyl}amino)butyl]boronic acid …
Matched Iupac: … [(1R)-3-methyl-1-[(2S)-3-phenyl-2-[(pyrazin-2-yl)formamido]propanamido]butyl]boronic acid …
Matched Description: … Bortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma ... and mantle cell lymphoma. ... ubiquitin-proteasome pathway: reversible inhibition of the 26S proteasome, leading to cell cycle arrest and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Acids ... Boronic Acids ... Acids, Noncarboxylic …
Matched Products: … BORTEZOMIB DR. REDDY'S …
Matched Iupac: … [(1R)-3-methyl-1-[(2S)-3-phenyl-2-[(pyrazin-2-yl)formamido]propanamido]butyl]boronic acid …
Matched Description: … Bortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma ... and mantle cell lymphoma. ... ubiquitin-proteasome pathway: reversible inhibition of the 26S proteasome, leading to cell cycle arrest and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Acids ... Boronic Acids ... Acids, Noncarboxylic …
Matched Products: … BORTEZOMIB DR. REDDY'S …
Dornase alfa
Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. It is produced in genetically modified Chinese hamster ovary (CHO) cells using recombinant DNA technology. The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and...
Approved
Matched Synonyms: … Dornase alpha …
Matched Description: … Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and 5´-phosphooligonucleotide end products ... Enzymatic breakdown of this extracellular DNA appears to reduce sputum viscosity and viscoelasticity. ... The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cough and Cold Preparations ... Enzymes and Coenzymes …
Matched Description: … Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and 5´-phosphooligonucleotide end products ... Enzymatic breakdown of this extracellular DNA appears to reduce sputum viscosity and viscoelasticity. ... The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cough and Cold Preparations ... Enzymes and Coenzymes …
Nadofaragene firadenovec
Nadofaragene firadenovec (nadofaragene firadenovec-vncg) is a recombinant non-replicating adenovirus serotype 5 vector containing a transgene encoding human interferon alfa-2b (IFNα2b). It was approved by the FDA on December 2022 for the treatment of high-risk Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ (CIS) with or without...
Approved
Investigational
Matched Synonyms: … alpha-2b) gene under the control of the cytomegalovirus (cmv) immediate-early enhancer/promoter ... Replication-deficient adenovirus type 5 (ad5) vector encoding the human interferon alpha 2 (ifna2, interferon …
Matched Description: … [L44381,L44431] BCG-unresponsive NMIBC has a high recurrence and is notably difficult to treat. ... firadenovec is formulated with an excipient (Syn-3) that facilitates gene transfer across the urothelium and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Cellular and Gene Therapy ... Antineoplastic cell and gene therapy …
Matched Description: … [L44381,L44431] BCG-unresponsive NMIBC has a high recurrence and is notably difficult to treat. ... firadenovec is formulated with an excipient (Syn-3) that facilitates gene transfer across the urothelium and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Cellular and Gene Therapy ... Antineoplastic cell and gene therapy …
2'-deoxyuridine 5'-alpha,beta-imido-diphosphate
Experimental
Matched Name: … 2'-deoxyuridine 5'-alpha,beta-imido-diphosphate …
Matched Iupac: … 1,2,3,4-tetrahydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)amino]phosphonic acid …
Matched Iupac: … 1,2,3,4-tetrahydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)amino]phosphonic acid …
5-Alpha-Androstane-3-Beta,17beta-Diol
Experimental
Matched Name: … 5-Alpha-Androstane-3-Beta,17beta-Diol …
North-methanocarbathymidine
Investigational
Matched Synonyms: … .,2.alpha.,4.beta.,5.alpha ... 2,4(1h,3h)-pyrimidinedione, 1-(4-hydroxy-5-(hydroxymethyl)bicyclo(3.1.0)hex-2-yl)-5-methyl-, (1s-(1.alpha …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
MMDA
MMDA, or 3-methoxy-4,5-methylenedioxyamphetamine, is a member of the amphetamine drug class with stimulant and psychedelic properties. It also acts as an entheogen and an entactogen. MMDA bears resemblance to the psychopharmacologically active essential oils elemicin and myristicin found in nutmeg. The effects of MMDA includes feelings of euphoria and warmth,...
Experimental
Illicit
Matched Synonyms: … 3-Methoxy-alpha-methyl-4,5-methylenedioxyphenethylamine …
Matched Description: … It also acts as an entheogen and an entactogen. ... or 3-methoxy-4,5-methylenedioxyamphetamine, is a member of the amphetamine drug class with stimulant and ... MMDA bears resemblance to the psychopharmacologically active essential oils elemicin and myristicin found …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Description: … It also acts as an entheogen and an entactogen. ... or 3-methoxy-4,5-methylenedioxyamphetamine, is a member of the amphetamine drug class with stimulant and ... MMDA bears resemblance to the psychopharmacologically active essential oils elemicin and myristicin found …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Displaying drugs 3101 - 3125 of 4014 in total