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Displaying drugs 301 - 325 of 7747 in total
Encainide
All drug products containing encainide hydrochloride. Encainide hydrochloride, formerly marketed as Enkaid capsules, was associated with increased death rates in patients who had asymptomatic heart rhythm abnormalities after a recent heart attack. The manufacturer of Enkaid capsules voluntarily withdrew the product from the US market on December 16, 1991.
Approved
Investigational
Withdrawn
Matched Synonyms: … (±)-2'-[2-(1-methyl-2-piperidyl)ethyl]-p-anisanilide ... 4-methoxy-2'-[2-(1-methyl-2-piperidyl)ethyl]benzanilide ... (±)-4-methoxy-N-(2-(2-(1-methyl-2-piperidinyl)ethyl)phenyl)benzamide …
Matched Iupac: … 4-methoxy-N-{2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl}benzamide …
Matched Iupac: … 4-methoxy-N-{2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl}benzamide …
Fexinidazole
Human African trypanosomiasis (HAT, also colloquially referred to as sleeping sickness), caused by T. brucei gambiense and T. brucei rhodesiense, remains a moderate risk (>1/10,000 inhabitants per year in endemic areas) despite focussed control efforts. Transmitted by the bite of an infected tsetse fly, HAT is biphasic with a first...
Approved
Investigational
Matched Iupac: … 1-methyl-2-{[4-(methylsulfanyl)phenoxy]methyl}-5-nitro-1H-imidazole …
Matched Categories: … MATE 2 Inhibitors ... MATE 2-K Inhibitors …
Matched Categories: … MATE 2 Inhibitors ... MATE 2-K Inhibitors …
Valproic acid
Valproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in 1881 by Beverly S. Burton. It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a century. In 1963, a serendipitous discovery was made by George Carraz during his investigations into...
Approved
Investigational
Matched Synonyms: … 2-Propylvaleric Acid ... 2-propyl-pentanoic acid ... 2-Propylpentanoic Acid …
Matched Iupac: … 2-propylpentanoic acid …
Matched Salts cas: … 1069-66-5 …
Matched Products: … EPILIM SYRUP 200 mg/5 ml ... hovid-Valproate Liquid 200 mg/5 ml ... ACIDO VALPROICO 100 MG/ ML POR 5 ML …
Matched Iupac: … 2-propylpentanoic acid …
Matched Salts cas: … 1069-66-5 …
Matched Products: … EPILIM SYRUP 200 mg/5 ml ... hovid-Valproate Liquid 200 mg/5 ml ... ACIDO VALPROICO 100 MG/ ML POR 5 ML …
Sodium citrate
Sodium citrate is the sodium salt of citric acid. It is white, crystalline powder or white, granular crystals, slightly deliquescent in moist air, freely soluble in water,
practically insoluble in alcohol. Like citric acid, it has a sour taste.
From the medical point of view, it is used as alkalinizing...
Approved
Investigational
Matched Iupac: … trisodium 2-hydroxypropane-1,2,3-tricarboxylate …
Matched Mixtures name: … Cytra-2 ... Cytra-2 ... Virtrate-2 …
Matched Mixtures name: … Cytra-2 ... Cytra-2 ... Virtrate-2 …
Clemastine
An ethanolamine-derivative, first generation histamine H1 antagonist used in hay fever, rhinitis, allergic skin conditions, and pruritus. It causes drowsiness.
Approved
Investigational
Matched Synonyms: … (+)-(2R)-2-(2-(((R)-p-chloro-α-methyl-α-phenylbenzyl)oxy)ethyl)-1-methylpyrrolidine ... (+)-(2R)-2-[2-[[(R)-p-chloro-α-methyl-α-phenylbenzyl]oxy]ethyl]-1-methylpyrrolidine …
Matched Iupac: … (2R)-2-{2-[1-(4-chlorophenyl)-1-phenylethoxy]ethyl}-1-methylpyrrolidine …
Matched Products: … CLEMAXCLIN® 2 MG/2ML SOLUCIÓN INYECTABLE. …
Matched Iupac: … (2R)-2-{2-[1-(4-chlorophenyl)-1-phenylethoxy]ethyl}-1-methylpyrrolidine …
Matched Products: … CLEMAXCLIN® 2 MG/2ML SOLUCIÓN INYECTABLE. …
Becaplermin
Becaplermin is produced by recombinant DNA technology by insertion of the gene for the B chain of platelet derived growth factor (PDGF) into the yeast, Saccharomyces cerevisiae. Becaplermin has a molecular weight of approximately 25 KD and is a homodimer composed of two identical polypeptide chains that are bound together...
Approved
Investigational
Matched Synonyms: … PDGF-2 …
Esmolol
Esmolol, commonly marketed under the trade name Brevibloc, is a cardioselective beta-1 receptor blocker. It has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses. It works by blocking beta-adrenergic receptors in the heart, which leads to decreased...
Approved
Withdrawn
Matched Synonyms: … (±)-methyl p-(2-hydroxy-3-(isopropylamino)propoxy)hydrocinnamate ... methyl p-(2-hydroxy-3-(isopropylamino)propoxy)hydrocinnamate ... Methyl 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)benzenepropanoate …
Matched Iupac: … methyl 3-(4-{2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)propanoate …
Matched Iupac: … methyl 3-(4-{2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)propanoate …
Influenza B virus B/Singapore/INFTT-16-0610/2016 hemagglutinin antigen (MDCK cell derived, propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Pantothenic acid
Pantothenic acid, also called pantothenate or vitamin B5 (a B vitamin), is a water-soluble vitamin discovered by Roger J. Williams in 1919. For many animals, pantothenic acid is an essential nutrient as it is required to synthesize coenzyme-A (CoA), as well as to synthesize and metabolize proteins, carbohydrates, and fats....
Approved
Nutraceutical
Vet approved
Matched Salts cas: … 867-81-2 …
Matched Mixtures name: … Complex 5 - Pwr ... Pregvit Folic 5 ... Pregvit Folic 5 …
Matched Products: … แพนโทธีนิค 200 (วิตามินบี5) …
Matched Mixtures name: … Complex 5 - Pwr ... Pregvit Folic 5 ... Pregvit Folic 5 …
Matched Products: … แพนโทธีนิค 200 (วิตามินบี5) …
Tapinarof
Tapinarof is a novel, first-in-class, small-molecule AhR agonist that is indicated for the treatment of adult psoriasis. It is available as a topical cream to be applied to the affected area once daily.[L41845, A248790] Tapiranof was first discovered as a metabolite (3,5-dihydroxy-4-isopropylstilbene) produced in Photorhabdus luminescens, a gram-negative bacillus that...
Approved
Investigational
Matched Iupac: … 5-[(E)-2-phenylethenyl]-2-(propan-2-yl)benzene-1,3-diol …
Tepotinib
Tepotinib is a MET tyrosine kinase inhibitor intended to treat a variety of MET-overexpressing solid tumors. It was originally developed in partnership between EMD Serono and the University of Texas M.D. Anderson Cancer Center in 2009 and has since been investigated in the treatment of neuroblastoma, gastric cancers, non-small cell...
Approved
Investigational
Matched Iupac: … 3-{1-[(3-{5-[(1-methylpiperidin-4-yl)methoxy]pyrimidin-2-yl}phenyl)methyl]-6-oxo-1,6-dihydropyridazin …
Matched Categories: … MATE 2 Inhibitors …
Matched Categories: … MATE 2 Inhibitors …
Cilgavimab
SARS-CoV-2, the causative agent of COVID-19, enters cells via the interaction between the trimeric spike (S) glycoprotein and host cell angiotensin-converting enzyme 2 (ACE2). Blocking the interaction between the receptor-binding domain (RBD) of the S1 subunit and ACE2 inhibits viral host cell entry; animal studies indicate that antibodies capable of...
Approved
Investigational
Matched Description: … (S) glycoprotein and host cell angiotensin-converting enzyme 2 (ACE2). ... SARS-CoV-2, the causative agent of COVID-19, enters cells via the interaction between the trimeric spike ... overlap with that of [tixagevimab], the two can be administered to synergistically impair SARS-CoV-2 …
Tixagevimab
SARS-CoV-2, the causative agent of COVID-19, enters cells via the interaction between the trimeric spike (S) glycoprotein and host cell angiotensin-converting enzyme 2 (ACE2). Blocking the interaction between the receptor-binding domain (RBD) of the S1 subunit and ACE2 inhibits viral host cell entry; animal studies indicate that antibodies capable of...
Approved
Investigational
Matched Description: … (S) glycoprotein and host cell angiotensin-converting enzyme 2 (ACE2). ... SARS-CoV-2, the causative agent of COVID-19, enters cells via the interaction between the trimeric spike ... cells derived from a neutralizing antibody isolated from a patient with a natural history of SARS-CoV-2 …
Solriamfetol
Solriamfetol marketed under the brand name Sunosi by Jazz Pharmaceuticals in the United States is a dopamine and norepinephrine reuptake inhibitor (DNRI) indicated in treating daytime sleepiness associated with narcolepsy or obstructive sleep apnea[FDA Label]. Solriamfetol was given FDA approval in 2019[FDA Label].
Approved
Matched Synonyms: … (2R)-2-amino-3-phenylpropyl carbamate …
Matched Iupac: … (2R)-2-amino-3-phenylpropyl carbamate …
Matched Iupac: … (2R)-2-amino-3-phenylpropyl carbamate …
Zaleplon
Zaleplon is a sedative/hypnotic, mainly used for insomnia. It is known as a nonbenzodiazepine hypnotic. Zaleplon interacts with the GABA receptor complex and shares some of the pharmacological properties of the benzodiazepines. Zaleplon is a schedule IV drug in the United States.
Approved
Illicit
Investigational
Matched Products: … SONATA ® 5 MG. CAPSULAS …
Penbutolol
Penbutolol is a drug in the beta-blocker class used to treat hypertension. Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker. Penbutolol can act as a partial agonist at beta adrenergic receptors, since it is a sympathomimetric drug. Penbutolol also demonstrates high binding affinity to the...
Approved
Investigational
Matched Synonyms: … (2S)-1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol …
Matched Iupac: … (2S)-1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol …
Matched Description: … Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker ... Penbutolol also demonstrates high binding affinity to the 5-hydroxytryptamine receptor 1A with antagonistic …
Matched Salts cas: … 38363-32-5 …
Matched Categories: … Serotonin 5-HT1 Receptor Antagonists ... Serotonin 5-HT1A Receptor Antagonists …
Matched Iupac: … (2S)-1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol …
Matched Description: … Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker ... Penbutolol also demonstrates high binding affinity to the 5-hydroxytryptamine receptor 1A with antagonistic …
Matched Salts cas: … 38363-32-5 …
Matched Categories: … Serotonin 5-HT1 Receptor Antagonists ... Serotonin 5-HT1A Receptor Antagonists …
Oteracil
Oteracil is an adjunct to antineoplastic therapy, used to reduce the toxic side effects associated with chemotherapy. Approved by the European Medicines Agency (EMA) in March 2011, Oteracil is available in combination with DB09257 and DB09256 within the commercially available product "Teysuno". The main active ingredient in Teysuno is DB09256,...
Approved
Matched Synonyms: … 5-azaorotic acid …
Matched Iupac: … 4,6-dioxo-1,4,5,6-tetrahydro-1,3,5-triazine-2-carboxylic acid …
Matched Description: … The main active ingredient in Teysuno is [DB09256], a pro-drug of [DB00544] (5-FU), which is a cytotoxic ... Oteracil's main role within Teysuno is to reduce the activity of 5-FU within normal gastrointestinal ... By mimicking a class of compounds called "pyrimidines" that are essential components of RNA and DNA, 5- …
Matched Salts cas: … 2207-75-2 …
Matched Iupac: … 4,6-dioxo-1,4,5,6-tetrahydro-1,3,5-triazine-2-carboxylic acid …
Matched Description: … The main active ingredient in Teysuno is [DB09256], a pro-drug of [DB00544] (5-FU), which is a cytotoxic ... Oteracil's main role within Teysuno is to reduce the activity of 5-FU within normal gastrointestinal ... By mimicking a class of compounds called "pyrimidines" that are essential components of RNA and DNA, 5- …
Matched Salts cas: … 2207-75-2 …
Vernakalant
Vernakalant was developed by Cardiome Pharma as as an antiarrhythmic drug intended for rapid conversion of atrial fibrillation to sinus rhythm. It acts as an atypical class III antiarrhythmic drug that potentiates its effect in higher heart rates. Intravenous formulation was approved in Europe in September 2010 as Brinavess and...
Approved
Investigational
Matched Synonyms: … (3R)-1-((1R,2R)-2-(2-(3,4-dimethoxyphenyl)ethoxy)cyclohexyl)pyrrolidin-3-ol …
Matched Iupac: … (3R)-1-[(1R,2R)-2-[2-(3,4-dimethoxyphenyl)ethoxy]cyclohexyl]pyrrolidin-3-ol …
Matched Iupac: … (3R)-1-[(1R,2R)-2-[2-(3,4-dimethoxyphenyl)ethoxy]cyclohexyl]pyrrolidin-3-ol …
Infigratinib
Infigratinib is a pan-fibroblast growth factor receptor (FGFR) kinase inhibitor. By inhibiting the FGFR pathway, which is often aberrated in cancers such as cholangiocarcinoma, infigratinib suppresses tumour growth. Cholangiocarcinoma is the most common primary malignancy affecting the biliary tract and the second most common primary hepatic malignancy. Infitratinib is a...
Approved
Investigational
Matched Description: … locally advanced or metastatic cholangiocarcinoma in adults with a fibroblast growth factor receptor 2 …
Matched Categories: … MATE 2 Inhibitors ... Fibroblast Growth Factor 2, antagonists & inhibitors …
Matched Categories: … MATE 2 Inhibitors ... Fibroblast Growth Factor 2, antagonists & inhibitors …
Zinc
A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with anemia, short stature, hypogonadism, impaired wound...
Approved
Investigational
Matched Description: … polymorphism of the common polymorphism in zinc transporter _SLC30A8/ZnT8_ may increase susceptibility to type 2 …
Matched Mixtures name: … QBx (formerly known as PHI-5, K041059) ... FENYSOL-Z 40 MG + 15 MG/5 ML ŞURUP, 100 ML ... For-2 …
Matched Products: … ZINCO-K 15MG/5 ML 28 KASIK SURUP ... ZINCLOMIN 15 MG/5 ML 100 ML SURUP ... ZINCO-K 15MG/5 ML KASIK SURUP, 20 ADET …
Matched Mixtures name: … QBx (formerly known as PHI-5, K041059) ... FENYSOL-Z 40 MG + 15 MG/5 ML ŞURUP, 100 ML ... For-2 …
Matched Products: … ZINCO-K 15MG/5 ML 28 KASIK SURUP ... ZINCLOMIN 15 MG/5 ML 100 ML SURUP ... ZINCO-K 15MG/5 ML KASIK SURUP, 20 ADET …
Permethrin
A pyrethroid insecticide commonly used in the treatment of lice infestations and scabies. It is a yellow to light orange-brown, low melt-ing solid or viscous liquid.
Approved
Investigational
Matched Products: … Infectoscab 5% Creme ... PIOKILL ® CREMA 5% ... Nix Dermal Cream 5% …
Flavone
Approved
Experimental
Matched Synonyms: … 2-Phenyl-4-chromone ... 2-phenylchromone ... 2-Phenyl-4-benzopyron …
Matched Iupac: … 2-phenyl-4H-chromen-4-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 2-phenyl-4H-chromen-4-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
D-alpha-Tocopherol acetate
Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the...
Approved
Nutraceutical
Vet approved
Matched Iupac: … (2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-yl acetate …
Matched Description: … 6 months, males = 5 mg (7.5 IU) females = 5 mg (7.5 IU) in ages 7-12 months, males = 6 mg (9 IU) females ... allowances (RDAs) for vitamin E alpha-tocopherol are: males = 4 mg (6 IU) females = 4 mg (6 IU) in ages 0- …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … 6 months, males = 5 mg (7.5 IU) females = 5 mg (7.5 IU) in ages 7-12 months, males = 6 mg (9 IU) females ... allowances (RDAs) for vitamin E alpha-tocopherol are: males = 4 mg (6 IU) females = 4 mg (6 IU) in ages 0- …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Viltolarsen
Duchenne muscular dystrophy (DMD) is an X-linked recessive allelic disorder characterized by a lack of functional dystrophin protein, which leads to progressive ambulatory, pulmonary, and cardiac function and is invariably fatal. A related, albeit a less severe, form of muscular dystrophy known as Becker muscular dystrophy (BMD) is characterized by...
Approved
Investigational
Mebutamate
Mebutamate is a sedative and anxiolytic drug with anti-hypertensive (blood pressure lowering) effects comparable to those of other barbiturates but is only around 1/3rd the potency of secobarbital as a sedative. Side effects include dizziness and headaches.
Approved
Matched Synonyms: … 2-Methyl-2-sec-butyl-1,3-propanediol dicarbamate ... 2-sec-Butyl-2-methyl-1,3-propanediol dicarbamate ... 2-sec-Butyl-2-methyltrimethylene dicarbamate …
Matched Iupac: … 2-[(carbamoyloxy)methyl]-2,3-dimethylpentyl carbamate …
Matched Iupac: … 2-[(carbamoyloxy)methyl]-2,3-dimethylpentyl carbamate …
Displaying drugs 301 - 325 of 7747 in total