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Displaying drugs 301 - 325 of 11769 in total

Vildagliptin

Vildagliptin (LAF237) is an orally active antihyperglycemic agent that selectively inhibits the dipeptidyl peptidase-4 (DPP-4) enzyme. It is used to manage type II diabetes mellitus, where GLP-1 secretion and insulinotropic effects are impaired. By inhibiting DPP-4, vildagliptin prevents the degradation of glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP),...
Approved
Investigational
Matched Iupac: … (2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}pyrrolidine-2-carbonitrile …
Matched Mixtures name: … JALRA ®M 50 MG /500 MG ... JALRA® M 50 MG / 850 MG ... JALRA ®M 50 MG /500 MG …
Matched Products: … เดย์วัส 50 ... GALVUS 50 MG ... GALVUS (50 MG) …

Dicoumarol

Dicoumarol is an oral anticoagulant agent that works by interfering with the metabolism of vitamin K. In addition to its clinical use, it is also used in biochemical experiments as an inhibitor of reductases.
Approved
Matched Synonyms: … 3,3'-methylenebis(4-hydroxy-2H-1-benzopyran-2-one) …
Matched Iupac: … 4-hydroxy-3-[(4-hydroxy-2-oxo-2H-chromen-3-yl)methyl]-2H-chromen-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Repaglinide

Repaglinide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the meglitinide class of short-acting insulin secretagogues, which act by binding to β cells of the pancreas to stimulate insulin release. Repaglinide induces an early insulin response to meals decreasing postprandial blood...
Approved
Investigational
Matched Iupac: … 2-ethoxy-4-({[(1S)-3-methyl-1-[2-(piperidin-1-yl)phenyl]butyl]carbamoyl}methyl)benzoic acid …
Matched Mixtures name: … REPAMEF 2/500 MG EFERVESAN TABLET, 30 ADET ... REPAMEF 2/1000 MG EFERVESAN TABLET, 30 ADET ... REPAMEF 2/500 MG EFERVESAN TABLET, 90 ADET …
Matched Products: … NOVONORM TABLET 2 mg ... REPLIC 2 MG TABLET, 30 ADET ... SERGILEX 2 MG TABLET,90 ADET …

Human immunoglobulin G

Intravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human plasma via Cohn fractionation. The purification process includes cold alcohol fractionation, polyethylene glycol precipitation, and ion exchange chromatography. IVIg contains the same distribution of IgG antibody subclasses as is found in the general human population....
Approved
Investigational
Matched Products: … BERIGLOBINA P X 2 ML INYECTABLE ... INTRATECT ® X 50 ML ... PRIVIGEN 10% (5G/50 ML) …

Baricitinib

Baricitinib is a Janus kinase (JAK) inhibitor. JAKs are tyrosine protein kinases that play an important role in pro-inflammatory signaling pathways. Overactive JAKs have been implicated in autoimmune disorders, such as rheumatoid arthritis. By inhibiting the actions of JAK1 and JAK2, baricitinib attenuates JAK-mediated inflammation and immune responses. Baricitinib was...
Approved
Investigational
Matched Iupac: … 2-[1-(ethanesulfonyl)-3-(4-{7H-pyrrolo[2,3-d]pyrimidin-4-yl}-1H-pyrazol-1-yl)azetidin-3-yl]acetonitrile …
Matched Categories: … MATE 2 Inhibitors ... MATE 2 Substrates ... Heterocyclic Compounds, 2-Ring ... MATE 2 Substrates with a Narrow Therapeutic Index …
Matched Products: … โอลูเมียนท์ (2 มก.) ... UNAMİTY 2 MG FİLM KAPLI TABLET, 7 ADET ... UNAMİTY 2 MG FİLM KAPLI TABLET, 28 ADET …

Benzphetamine

A sympathomimetic agent with properties similar to dextroamphetamine. It is used in the treatment of obesity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1222)
Approved
Illicit
Matched Synonyms: … N-methyl-1-phenyl-N-(phenylmethyl)propan-2-amine …
Matched Iupac: … benzyl(methyl)[(2S)-1-phenylpropan-2-yl]amine …

Homatropine

Homatropine is an anticholinergic drug that acts as an antagonist at muscarinic acetylcholine receptors. It is present in antitussives, under the trade name Hycodan, in combination with hydrocodone (dihydrocodeinone) bitartrate indicated for the symptomatic relief of cough as oral tablets or solutions. Homatropine is included in subtherapeutic amounts as homatropine...
Approved
Matched Iupac: … (1R,3S,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 2-hydroxy-2-phenylacetate …
Matched Products: … HOMATRO 2% ... Isopto Homatropine 2% ... Minims Homatropine Hydrobromide 2% …

Polidocanol

Polidocanol is a sclerosing agent indicated to treat uncomplicated spider veins (varicose veins ≤1 mm in diameter) and uncomplicated reticular veins (varicose veins 1 to 3 mm in diameter) in the lower extremity. It is marketed under the brand names Asclera and Varithena. The formula for Polidocanol has the structural...
Approved
Matched Products: … Aethoxysklerol 2 % - Ampullen ... ATEROSKLEROL % 2 AMPUL, 5 ADET ... VARİKANOL % 2 ENJEKSİYONLUK ÇÖZELTİ …

Busulfan

Busulfan is a bifunctional alkylating agent, having a selective immunosuppressive effect on bone marrow. It is not a structural analog of the nitrogen mustards. It has been used in the palliative treatment of chronic myeloid leukemia (myeloid leukemia, chronic), but although symptomatic relief is provided, no permanent remission is brought...
Approved
Investigational
Matched Products: … MYRAN TABLETS 2 mg ... MYLERAN TABLETAS 2 MG ... Myleran 2 mg Filmtabletten …

Estazolam

A benzodiazepine with anticonvulsant, hypnotic, and muscle relaxant properties. It has been shown in some cases to be more potent than diazepam or nitrazepam.
Approved
Illicit
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … ESTA-2 ... ELGRAN-2 …

Sodium aurothiomalate

Sodium aurothiomalate is a gold compound that is used for its immunosuppressive anti-rheumatic effects. Gold Sodium Thiomalate is supplied as a solution for intramuscular injection containing 50 mg of Gold Sodium Thiomalate per mL. It is most effective in active progressive rheumatoid arthritis and of little or no value in...
Approved
Investigational
Matched Iupac: … disodium 2-(auriosulfanyl)butanedioate …
Matched Description: … Gold Sodium Thiomalate is supplied as a solution for intramuscular injection containing 50 mg of Gold …
Matched Products: … MIOCRIN 50 MG …

Isoniazid

Antibacterial agent used primarily as a tuberculostatic. It remains the treatment of choice for tuberculosis.
Approved
Investigational
Matched Mixtures name: … RIFAMPICIN 75 MG / ISONIAZID 50 MG (FDC 2 ANAK) ... RIFAMPICIN 75 MG / ISONIAZID 50 MG …
Matched Products: … I.N.H 300 MG TABLET, 50 ADET …

Etelcalcetide

Etelcalcetide is a calcimimetic drug for the treatment of secondary hyperparathyroidism in patients undergoing hemodialysis. Etelcalcetide was approved (trade name Parsabiv) for the treatment of secondary hyperparathyroidism (HPT) in adult patients with chronic kidney disease (CKD) on hemodialysis in February, 2017.
Approved
Investigational
Matched Iupac: … (2R)-2-amino-3-{[(2S)-2-{[(1R)-1-{[(1R)-4-carbamimidamido-1-{[(1R)-4-carbamimidamido-1-{[(1R)-4-carbamimidamido ... carbamoylbutyl]carbamoyl}ethyl]carbamoyl}butyl]carbamoyl}butyl]carbamoyl}butyl]carbamoyl}ethyl]carbamoyl}-2- …
Matched Products: … PARSABIV SOLUTION FOR INJECTION 10 mg/2 mL ... PARSABİV 10 MG/2 ML I.V. ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... PARSABİV 10 MG/2 ML I.V. ENJEKSİYONLUK ÇÖZELTİ, 6 ADET …

Guanfacine

Guanfacine, or BS 100-141,[A189838,A189841] is a selective alpha-A2 adrenergic receptor agonist initially indicated for the treatment of hypertension but is now indicated as an extended release tablet for the treatment of ADHD. Guanfacine was first described in the literature in 1974. Guanfacine was granted FDA approval on 27 October 1986.
Approved
Investigational
Matched Iupac: … N-carbamimidoyl-2-(2,6-dichlorophenyl)acetamide …
Matched Categories: … Adrenergic alpha-2 Receptor Agonists ... Central alpha-2 Adrenergic Agonist …
Matched Products: … GUAGO 2 MG UZATILMIŞ SALIMLI TABLET, 7 ADET ... GUAGO 2 MG UZATILMIŞ SALIMLI TABLET, 28 ADET ... ARİSLOW ER 2 MG UZATILMIŞ SALIMLI TABLET, 7 TABLET …

Topiramate

Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. It was initially approved by the FDA in 1996. In 2004, topiramate was approved for the prevention of migraine in adults.[A188309,L10544,L43478] Since 2012, the extended-release formulation has been approved in combination with phentermine for chronic weight management therapy...
Approved
Matched Products: … TOPAMAX 50 TABLET 50 mg ... เอพาเมท 50 ... MORAMAX 50 …

Salmeterol

Salmeterol is a long-acting beta-2 adrenergic receptor agonist drug that is currently prescribed for the treatment of asthma and chronic obstructive pulmonary disease COPD.[L11545,L11548,L11551,L11554,L11557] It has a longer duration of action than the short-acting beta-2 adrenergic receptor agonist, salbutamol. Salmeterol was first described in the literature in 1988. Salmeterol's structure...
Approved
Matched Iupac: … 4-(1-hydroxy-2-{[6-(4-phenylbutoxy)hexyl]amino}ethyl)-2-(hydroxymethyl)phenol …
Matched Description: … Salmeterol is a long-acting beta-2 adrenergic receptor agonist drug that is currently prescribed for ... [L11545,L11548,L11551,L11554,L11557] It has a longer duration of action than the short-acting beta-2 …
Matched Mixtures name: … SERETIDE 50/100 ACCUHALER 50 mcg/100 mcg ... SERETIDE 50/250 ACCUHALER 50 mcg/250 mcg ... SERETIDE 50/500 ACCUHALER 50 mcg/500 mcg …
Matched Categories: … Adrenergic beta-2 Receptor Agonists ... Selective Beta 2-adrenergic Agonists …
Matched Products: … SEREVENT DISKUS 50 MCG, 28 DOZ ... SEREVENT DISKUS 50 MCG, 60 DOZ ... SALMECAP 50 MCG INHALASYON ICIN TOZ ICEREN KAPSUL, 60 ADET …

Levetiracetam

Levetiracetam is a drug within the pyrrolidine class that is used to treat various types of seizures stemming from epileptic disorders. It was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated to other anti-epileptic drugs (AEDs).[L8606,L8600,L8615] Levetiracetam possesses a wide therapeutic index[L8615,A185918]...
Approved
Matched Iupac: … (2S)-2-(2-oxopyrrolidin-1-yl)butanamide …
Matched Products: … EPI-NO 250 MG FILM TABLET, 50 ADET ... EPI-NO 500 MG FILM TABLET, 50 ADET ... EPI-NO 750 MG FILM TABLET, 50 ADET …

Riluzole

A glutamate antagonist (receptors, glutamate) used as an anticonvulsant (anticonvulsants) and to prolong the survival of patients with amyotrophic lateral sclerosis. Riluzole is marketed as Rilutek by Sanofi.
Approved
Investigational
Matched Iupac: … 6-(trifluoromethoxy)-1,3-benzothiazol-2-amine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … DOLVIO 50 ... RILUTEK 50 MG ... RILUTEK TABLET 50 mg …

Eplerenone

Eplerenone, an aldosterone receptor antagonist similar to spironolactone, has been shown to produce sustained increases in plasma renin and serum aldosterone, consistent with inhibition of the negative regulatory feedback of aldosterone on renin secretion. The resulting increased plasma renin activity and aldosterone circulating levels do not overcome the effects of...
Approved
Matched Iupac: … methyl (1'R,2R,2'S,9'R,10'R,11'S,15'S,17'R)-2',15'-dimethyl-5,5'-dioxo-18'-oxaspiro[oxolane-2,14'-pentacyclo …
Matched Products: … EPLEDAY 50 MG FILM KAPLI TABLET, 50 ADET ... INSPRA 50 MG ... CARDIONONA 50 MG …

Ceftazidime

Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis,...
Approved
Matched Iupac: … 1-{[(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetamido]-2-carboxylato ... -8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}pyridin-1-ium …
Matched Salts cas: … 78439-06-2 ... 73547-61-2 …
Matched Mixtures name: … ZAVİCEFTA 2 G/0.5 G İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 10 ADET …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … FORTUM FOR INJECTION 2 g/vial ... Kefazim 2 g Trockenstechampulle ... IESETUM 2 G IV/IM ENJEKTABL FLAKON, 1 ADET …

Fluvoxamine

Fluvoxamine is an antidepressant which functions pharmacologically as a selective serotonin reuptake inhibitor. Though it is in the same class as other SSRI drugs, it is most often used to treat obsessive-compulsive disorder. Fluvoxamine has been in use in clinical practice since 1983 and has a clinical trial database comprised...
Approved
Investigational
Matched Iupac: … (E)-(2-aminoethoxy)({5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene})amine …
Matched Products: … FLUVOXIN 50 ... FAVERIN 50 MG ... Fluvoxamine-50 …

Mirabegron

Mirabegron is a sympathomimetic beta-3 adrenergic receptor agonist used to relax the smooth muscle of the bladder in the treatment of urinary frequency and incontinence. It is unique amongst overactive bladder treatment options in that, unlike other treatments such as solifenacin and darifenacin, it lacks significant antimuscarinic activity, which is...
Approved
Matched Iupac: … 2-(2-amino-1,3-thiazol-4-yl)-N-[4-(2-{[(2R)-2-hydroxy-2-phenylethyl]amino}ethyl)phenyl]acetamide …
Matched Products: … BETMIGA 50 MG UZATILMIŞ SALIMLI FILM TABLET ,50 TABLET ... BETMIGA 50 MG ... BETMIGA 25 MG UZATILMIŞ SALIMLI FILM TABLET , 50 TABLET …

Sunitinib

Sunitinib is a small-molecule multi-targeted receptor tyrosine kinase (RTK) inhibitor. On January 26, 2006, the agent was formally approved by the US FDA for the indications of treating renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST). For these purposes, sunitinib is generally available as an orally administered formulation....
Approved
Investigational
Matched Iupac: … N-[2-(diethylamino)ethyl]-5-{[(3Z)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-2,4-dimethyl …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … Sutent Capsule 50 mg ... SUTENT® CAPSULAS 50 MG ... Sunitinib Mylan 50 mg Hartkapseln …

Pomalidomide

Pomalidomide, an analogue of thalidomide, is an immunomodulatory antineoplastic agent. FDA approved on February 8, 2013.
Approved
Matched Iupac: … 4-amino-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … POMALYST 2 MG ... POMALEM 2 MG SERT KAPSÜL, 21 ADET ... IMNOVID 2 MG SERT KAPSÜL ,21 KAPSÜL …

Miglitol

Miglitol inhibits the breakdown complex carbohydrates into glucose. It is primarily used in diabetes mellitus type 2 for establishing greater glycemic control by preventing the digestion of carbohydrates (such as disaccharides, oligosaccharides, and polysaccharides) into monosaccharides which can be absorbed by the body. Miglitol should be taken at the start...
Approved
Matched Iupac: … (2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol …
Matched Description: … It is primarily used in diabetes mellitus type 2 for establishing greater glycemic control by preventing …
Matched Products: … DIASTABOL 50 MG ... MIOL 50 MG TABLET ,100 TABLET ... MIGLITEC 50 MG TABLET, 100 ADET …
Displaying drugs 301 - 325 of 11769 in total