Displaying drugs 3401 - 3425 of 8033 in total
Alitretinoin
An important regulator of gene expression during growth and development, and in neoplasms. Tretinoin, also known as retinoic acid and derived from maternal vitamin A, is essential for normal growth; and embryonic development. An excess of tretinoin can be teratogenic. It is used in the treatment of psoriasis; acne vulgaris;...
Approved
Investigational
Matched Description: … An excess of tretinoin can be teratogenic. ... An important regulator of gene expression during growth and development, and in neoplasms. ... It is used in the treatment of psoriasis; acne vulgaris; and several other skin diseases. …
Tripelennamine
A histamine H1 antagonist with low sedative action but frequent gastrointestinal irritation. It is used to treat asthma; HAY fever; urticaria; and rhinitis; and also in veterinary applications. Tripelennamine is administered by various routes, including topically.
Approved
Vet approved
Trifluoperazine
A phenothiazine with actions similar to chlorpromazine. It is used as an antipsychotic and an antiemetic.
Approved
Investigational
Cilastatin
Cilastatin is an inhibitor of renal dehydropeptidase, an enzyme responsible for both the metabolism of thienamycin beta-lactam antibiotics as well as conversion of leukotriene D4 to leukotriene E4. Since the antibiotic, imipenem, is one such antibiotic that is hydrolyzed by dehydropeptidase, cilastatin is used in combination with imipenem to prevent...
Approved
Investigational
Matched Description: … Cilastatin is an inhibitor of renal dehydropeptidase, an enzyme responsible for both the metabolism of ... thienamycin beta-lactam antibiotics as well as conversion of leukotriene D4 to leukotriene E4. ... The first combination product containing both drugs was approved by the FDA in November of 1985 under …
Quinestrol
The 3-cyclopentyl ether of ethinyl estradiol.
Approved
Matched Description: … The 3-cyclopentyl ether of ethinyl estradiol. …
Streptococcus pneumoniae type 19F capsular polysaccharide diphtheria CRM197 protein conjugate antigen
Streptococcus pneumoniae type 19F capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 19F individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). It is...
Approved
Matched Description: … protein, a nontoxic variant of diphtheria toxin isolated from cultures of *Corynebacterium diphtheriae ... the capsular antigens of *Streptococcus pneumoniae* serotype 19F individually conjugated to the CRM197 ... polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of …
Streptococcus pneumoniae type 23F capsular polysaccharide diphtheria CRM197 protein conjugate antigen
Streptococcus pneumoniae type 23f capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 23F individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). It is...
Approved
Matched Description: … protein, a nontoxic variant of diphtheria toxin isolated from cultures of *Corynebacterium diphtheriae ... the capsular antigens of *Streptococcus pneumoniae* serotype 23F individually conjugated to the CRM197 ... polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of …
Human papillomavirus type 18 L1 capsid protein antigen
Human papillomavirus type 18 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus...
Approved
Investigational
Matched Description: … It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused ... The vaccine is prepared from the purified virus-like particles (VLPs) of the major capsid (L1) protein ... of HPV Types 6, 11, 16, and 18, which are produced by separate fermentations in recombinant *Saccharomyces …
Brodalumab
Brodalumab has been used in trials studying the treatment of Asthma, Psoriasis, Crohn's Disease, Psoriatic Arthritis, and Rheumatoid Arthritis. Brodalumab was FDA approved in February, 2017 as Siliq for the treatment of moderate-to-severe plaque psoriasis.
Approved
Investigational
Matched Description: … Brodalumab has been used in trials studying the treatment of Asthma, Psoriasis, Crohn's Disease, Psoriatic ... Brodalumab was FDA approved in February, 2017 as Siliq for the treatment of moderate-to-severe plaque …
Streptococcus pneumoniae type 22F capsular polysaccharide diphtheria CRM197 protein conjugate antigen
Streptococcus pneumoniae type 22F capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 22F individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). It is...
Approved
Matched Description: … protein, a nontoxic variant of diphtheria toxin isolated from cultures of *Corynebacterium diphtheriae ... the capsular antigens of *Streptococcus pneumoniae* serotype 22F individually conjugated to the CRM197 ... polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of …
Influenza A virus A/Darwin/6/2021 (H3N2) recombinant hemagglutinin antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Description: … This defense includes the production of humoral immunity through the development of antibodies and of ... A seasonally-specific component of the influenza vaccine. ... cell-mediated immunity through the production of T-lymphocytes. …
Influenza B virus B/Austria/1359417/2021 recombinant hemagglutinin antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Description: … This defense includes the production of humoral immunity through the development of antibodies and of ... A seasonally-specific component of the influenza vaccine. ... cell-mediated immunity through the production of T-lymphocytes. …
Influenza A Virus A/Sydney/5/2021 SAN-013 (H1N1) antigen (formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Description: … This defense includes the production of humoral immunity through the development of antibodies and of ... A seasonally-specific component of the influenza vaccine. ... cell-mediated immunity through the production of T-lymphocytes. …
Influenza A virus A/Victoria/4897/2022 IVR-238 (H1N1) Antigen (UV, formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Description: … This defense includes the production of humoral immunity through the development of antibodies and of ... A seasonally-specific component of the influenza vaccine. ... cell-mediated immunity through the production of T-lymphocytes. …
Influenza A virus A/Norway/31694/2022 (H1N1) live (attenuated) antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Description: … This defense includes the production of humoral immunity through the development of antibodies and of ... A seasonally-specific component of the influenza vaccine. ... cell-mediated immunity through the production of T-lymphocytes. …
Phenindione
An indandione that has been used as an anticoagulant. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higher incidence of severe adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p234)
Approved
Investigational
Matched Description: … of severe adverse effects. ... Phenindione has actions similar to warfarin, but it is now rarely employed because of its higher incidence …
Etoricoxib
Etoricoxib is a new COX-2 selective inhibitor. Current therapeutic indications are: treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout. Like any other COX-2 selective inhibitor, Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase enzyme (COX-2) to reduce the generation of prostaglandins (PGs) from arachidonic...
Approved
Investigational
Matched Description: … enzyme (COX-2) to reduce the generation of prostaglandins (PGs) from arachidonic acid. ... Like any other COX-2 selective inhibitor, Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase ... Current therapeutic indications are: treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis …
Trabectedin
Trabectedin, also referred as ET-743 during its development, is a marine-derived antitumor agent discovered in the Carribean tunicate Ecteinascidia turbinata and now produced synthetically. Trabectedin has a unique mechanism of action. It binds to the minor groove of DNA interfering with cell division and genetic transcription processes and DNA repair...
Approved
Investigational
Matched Description: … Trabectedin has a unique mechanism of action. ... It binds to the minor groove of DNA interfering with cell division and genetic transcription processes ... It is currently under evaluation for the treatment of breast cancer, prostate cancer, in addition to …
Radium Ra 223 dichloride
Radium Ra 223 Dichloride is a radiopharmaceutical containing the radioisotope radium-223 that emits short range but high linear energy alpha particles. As a cation, radium mimics calicum and binds to hydroxyapatite, which is a bone mineral found in areas of high bone turnover as seen in bone metastases. It was...
Approved
Investigational
Matched Description: … a cation, radium mimics calicum and binds to hydroxyapatite, which is a bone mineral found in areas of ... Dichloride should not be used in women who are pregnant or may become pregnant due to the high risk of …
Elosulfase alfa
Elosulfase alfa is a synthetic version of the enzyme N-acetylgalactosamine-6-sulfatase. It was approved by the FDA in 2014 for the treatment of Morquio syndrome. Elosulfase alfa was developed by BioMarin Pharmaceutical Inc. and is marketed under the brand Vimizim™. The recommended dose is 2 mg per kg given intravenously over...
Approved
Investigational
Matched Description: … It was approved by the FDA in 2014 for the treatment of Morquio syndrome. ... Elosulfase alfa is a synthetic version of the enzyme N-acetylgalactosamine-6-sulfatase. ... The recommended dose is 2 mg per kg given intravenously over a minimum range of 3.5 to 4.5 hours, based …
Aluminum zirconium pentachlorohydrate
Aluminum zirconium pentachlorohydrate is a common active ingredient in personal care products as an antiperspirant agent. Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing sweat from leaving the body.
Approved
Matched Description: … Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing …
Fluindione
Fluindione is under investigation for the treatment of Venous Thrombosis, Pulmonary Embolism, Permanent Atrial Fibrillation, and Anticoagulating Treatment on a Duration at Least 12-month-old Superior. Fluindione has been investigated for the treatment of Blood Coagulation Disorders.
Approved
Investigational
Matched Description: … Fluindione has been investigated for the treatment of Blood Coagulation Disorders. ... Fluindione is under investigation for the treatment of Venous Thrombosis, Pulmonary Embolism, Permanent …
Cobalt
A trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis. Except for radioactive forms...
Approved
Experimental
Withdrawn
Matched Description: … Except for radioactive forms of cobalt and cobalamin, the FDA withdrew its approval for the use of drug ... A trace element that is a component of vitamin B12. …
Carbon dioxide
Carbon dioxide is a colorless, odorless gas vital to life on Earth. This naturally occurring chemical compound is composed of a carbon atom covalently double bonded to two oxygen atoms. Medical Carbon Dioxide is a liquefied medicinal gas, supplied in cylinders filled to a high pressure. Medical Carbon Dioxide may...
Approved
Investigational
Vet approved
Matched Description: … tissue and removal of warts. ... This naturally occurring chemical compound is composed of a carbon atom covalently double bonded to two ... inflate body cavities during surgery (such as key-hole surgery), and in solid form (dry ice) for freezing of …
Displaying drugs 3401 - 3425 of 8033 in total