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Displaying drugs 326 - 350 of 5157 in total
Elapegademase is a PEGylated recombinant adenosine deaminase. It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues. Elapegademase is generated in E. coli,...
Approved
Matched Synonyms: … PEPTIDE PRODUCED IN ESCHERICHIA COLI, AN AVERAGE OF 13 RESIDUES ARE SUBSTITUTED ON N.ALPHA..1ALANINE AND ... 356)-PEPTIDE, PRODUCED IN ESCHERICHIA COLI, SUBSTITUTED ON N2 OF THE N-TERMINAL ALANYL RESIDUE (A1) AND ... -CARBOXY-.OMEGA.-METHOXY-, AMIDE WITH ADENOSINE DEAMINASE (SYNTHETIC) …
Matched Description: … with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues ... as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and ... [F1937] Elapegademase is generated in _E. coli_, developed by Leadiant Biosciences and FDA approved on …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Enzymes and Coenzymes …
A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. It inhibits gastric acid secretion, as well as pepsin and gastrins output. It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.
Approved
Investigational
Matched Synonyms: … 1-Cyano-2-methyl-3-(2-(((5-methyl-4-imidazolyl)methyl)thio)ethyl)guanidine ... 2-cyano-1-methyl-3-(2-(((5-methylimidazol-4-yl)methyl)thio)ethyl)guanidine ... N''-cyano-N-methyl-N'-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]thio}ethyl)guanidine …
Matched Iupac: … (Z)-N''-cyano-N-methyl-N'-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine …
Matched Description: … It inhibits gastric acid secretion, as well as pepsin and gastrins output. …
Matched Mixtures name: … Cimetidine 10% / Lidocaine 5% / Salicylic Acid 40% ... Cimetidine 5% / Ibuprofen 2% / Salicylic Acid 17% …
Matched Categories: … Alimentary Tract and Metabolism ... Metabolic Side Effects of Drugs and Substances ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) ... Acid Reducers ... Gastric Acid Lowering Agents …
Matched Products: … Up and Up Acid Reducer ... Leader Heartburn Relief ... Tagamet Liquid 60mg/ml …
Tefidsogene civaparvovec, formerly known as SB-913, is an investigational therapy for genome editing. It consists of an adeno-associated virus (AAV) type 2/6 vector and a zinc finger nuclease (ZFN) system that inserts a correct copy of the Iduronate 2-Sulfatase (IDS) gene into the albumin locus in hepatocytes. Developed by Sangamo...
Experimental
Matched Synonyms: … IDURONATE 2-SULFATASE (HIDS) TRANSGENE CASSETTE, ENCODING PARTS OF EXON 1 PLUS EXONS 2-9 FROM HIDS AND
Matched Description: … It consists of an adeno-associated virus (AAV) type 2/6 vector and a zinc finger nuclease (ZFN) system …
Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse. Although similar in structure to other opioids, it has minimal interaction with opioid receptors. Dextromethorphan was granted FDA approval before 3 December 1957.[A215412,L14997]
Approved
Matched Iupac: … (1S,9S,10S)-4-methoxy-17-methyl-17-azatetracyclo[7.5.3.0^{1,10}.0^{2,7}]heptadeca-2(7),3,5-triene …
Matched Description: … and also a drug of abuse. ... Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant …
Matched Mixtures name: … Poly-Vent DM ... Pulmo Calcio ... Care One Cold Mutli Symptom …
Matched Categories: … Cough and Cold Preparations ... Uncompetitive N-methyl-D-aspartate Receptor Antagonist ... Opium Alkaloids and Derivatives ... bupropion and dextromethorphan ... Excitatory Amino Acid Agents …
Matched Products: … Up and Up Cough Suppressant DM ... Up and Up 12 Hour Cough Relief ... Foster and Thrive 12 Hour Cough Relief …
RP-L102 is a lentiviral vector carrying the Fanconi Anemia-A (FANCA) gene currently being developed by Rocket Pharmaceuticals for the treatment of Fanconi anemia type A
Investigational
Matched Synonyms: … Autologous CD34+-enriched Hematopoietic Stem and Progenitor Cells Transduced with Lentiviral Vector Carrying …
C-CAR039 is an autologous Chimeric Antigen Receptors (CAR) T-cell therapy expressing CD19/CD20 bi-specific CAR.
Investigational
Matched Synonyms: … , non-replicating lentiviral vector, encoding a bispecific chimeric antigen receptor targeting CD19 and
Pacmilimab is under investigation in clinical trial NCT04596150 (Study to Evaluate the Safety and Antitumor Activity of CX-2009 Monotherapy and in Combination With CX-072 in Advanced Breast Cancer).
Investigational
Matched Synonyms: … HUMAN MONOCLONAL CX-072 .GAMMA.4-CHAIN), DISULFIDE WITH PRODOMAIN PROTEIN (SYNTHETIC MASKING MOIETY AND
Matched Description: … Pacmilimab is under investigation in clinical trial NCT04596150 (Study to Evaluate the Safety and Antitumor ... Activity of CX-2009 Monotherapy and in Combination With CX-072 in Advanced Breast Cancer). …
Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis,...
Approved
Matched Iupac: … -8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}pyridin-1-ium ... 1-{[(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetamido]-2-carboxylato …
Matched Description: … a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and ... through inhibition of essential PBPs, result in impaired cell wall homeostasis, loss of cell integrity, and ... [L32935] Ceftazidime was approved by the FDA on July 19, 1985, and is currently available either alone …
Matched Categories: … Sulfur Compounds …
Matched Products: … CEFTAZIDIME ALVOGEN POWDER FOR SOLUTION FOR INJECTION AND INFUSION 1G/ VIAL ... Ceftazidime and Dextrose ... CEFTAZIDIME KABI POWDER FOR SOLUTION FOR INJECTION 2G/VIAL …
Factor IX Complex is a sterile, lyophilized concentrate composed of a number of Vitamin K-dependent clotting factors found in functioning human plasma. Also known as prothrombin complex concentrate, products containing this complex often include Factor IX (antihemophilic factor B), Factor II (prothrombin), Factor X (Stuart-Prower Factor), and low levels of...
Approved
Investigational
Matched Synonyms: … Coagulation factor IX, II, VII and X in combination …
Matched Description: … Coagulation factors are purified from pooled human plasma and subsequently sterilized and treated. ... include Factor IX (antihemophilic factor B), Factor II (prothrombin), Factor X (Stuart-Prower Factor), and ... For example, Kcentra (FDA) also contains the antithrombotic proteins C and S, while Bebulin VH (FDA) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. (From AMA Drug Evaluations Annual,...
Approved
Investigational
Vet approved
Matched Description: … treatment of pre-eclampsia and eclampsia. ... A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the ... Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. …
Matched Mixtures name: … Sodium Sulfate, Potassium Sulfate and Magnesium Sulfate ... Sodium Sulfate, Potassium Sulfate and Magnesium Sulfate ... Sodium Sulfate, Potassium Sulfate and Magnesium Sulfate …
Matched Categories: … Metal cations ... Metal divalent cations ... Sulfur Acids ... Sulfuric Acids ... Calcium-Regulating Hormones and Agents …
Matched Products: … Spearmint and Menthol scented Natural Epsom Salt ... Epsom Salt Soaking Solution ... SULFATO DE MAGNESIO SOLUCION INYECTABLE …
Mucor circinelloides f. circinelloides allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, mucor circinelloides f. circinelloides …
Meropenem is a broad-spectrum carbapenem antibiotic. It is active against Gram-positive and Gram-negative bacteria. Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis of vital cell wall components, which leads to cell death. In August 2017, a combination antibacterial therapy under the market name vabomere...
Approved
Investigational
Matched Synonyms: … oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid ... (4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]thio}-6-[(1R)-1-hydroxyethyl]-4-methyl-7- …
Matched Iupac: … -7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid ... (4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl
Matched Description: … of vital cell wall components, which leads to cell death. ... It is active against Gram-positive and Gram-negative bacteria. ... Vabomere consists of meropenem and [DB12107] and is intravenously admininstered. …
Matched Categories: … meropenem and vaborbactam ... Sulfur Compounds …
Matched Products: … Meropenem and Sodium Chloride ... MEROPENEM ACIC ... Meropenem for Injection USP and Sodium Chloride Injection USP …
Factor IX (or Christmas factor) is one of the serine proteases of the coagulation system; it belongs to peptidase family S1. Deficiency of this protein causes hemophilia B.
Approved
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU ... Octaplex Powder and Solvent for Solution for Infusion ... BERIPLEX P/N 500 POWDER FOR SOLUTION FOR INJECTION …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes ... coagulation factor IX, II, VII and X in combination …
Matched Products: … IMMUNINE 120IU/ML Powder and solvent for solution for injection or infusion …
A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline medium, such as the aqueous humor, and is used therapeutically as a diagnostic aid in corneal injuries and corneal trauma. It has been approved by FDA for use in externally applied drugs...
Approved
Matched Synonyms: … D and C Yellow No. 7 …
Matched Description: … and corneal trauma. ... A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline ... medium, such as the aqueous humor, and is used therapeutically as a diagnostic aid in corneal injuries …
Matched Mixtures name: … Fluorescein Sodium & Benoxinate Hydrochloride Ophthalmic Solution, USP ... Fluorescein Sodium and Proparacaine Hydrochloride ... Fluorescein Sodium and Benoxinate Hydrochloride …
Matched Categories: … Indicators and Reagents …
Matched Products: … FLUORESCEINA POEN SOLUCION OFTALMICA ... FLUORESCEIN SERB 100MG/ML SOLUTION FOR INJECTION …
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor...
Approved
Investigational
Matched Synonyms: … Heparinic acid
Matched Description: … UH has a higher risk of bleeding and higher risk of osteoporosis in long term use. ... coagulation enzymes thrombin (factor IIa) and factor Xa. ... It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates …
Matched Mixtures name: … Heparin Sodium and Dextrose 5% Inj USP ... Heparin Sod and 0.9% Sod Chloride Inj …
Matched Salts name: … Heparin calcium
Matched Categories: … Blood and Blood Forming Organs ... Heparin and similars …
Matched Products: … Heparin Sodium and Sodium Chloride ... Heparin Sodium and Dextrose ... Heparin Lock Flush Solution Inj 10unit/ml …
Approved
Vet approved
Matched Synonyms: … Cortisol 21-acetate ... Hydrocortisone acetate ... Hydrocortisone 21-acetate
Matched Name: … Hydrocortisone acetate
Matched Iupac: … -oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl acetate
Matched Mixtures name: … Terra-Cortril ... Neomycin and Polymyxin B Sulfates and Bacitracin Zinc with Hydrocortisone Acetate ... Lidocaine HCl and Hydrocortisone Acetate
Matched Categories: … Hydrocortisone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … American Safety and First Aid ... Carmol HC ... Hydrocortisone Acetate
Experimental
Matched Synonyms: … Strychnos nux-vomica ... Nux vomica seed ... Nux vomica extract …
Matched Name: … Nux vomica extract …
Insulin lispro is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the pancreas...
Approved
Matched Description: … acids in the blood and a syndrome called ketoacidosis, which is a life-threatening medical emergency ... In the long term, elevated blood sugar levels increase the risk of heart attack, stroke, and diabetic ... chemical nomenclature [LYS(B28), PRO(B29)], insulin lispro differs from human insulin in that the amino acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Insulins and Analogues for Injection, Fast-Acting …
Matched Products: … Insulin Lispro Protamine and Insulin Lispro Injectable Suspension Mix75/25 KwikPen …
Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms. It is one of the most common skin and mucous membrane antiseptic agents in use today. The molecule itself is a cationic bis-guanide consisting of...
Approved
Vet approved
Withdrawn
Matched Description: … [A190417] The molecule itself is a cationic bis-guanide consisting of two 4-chlorophenyl rings and two ... Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental ... [L11512] It is one of the most common skin and mucous membrane antiseptic agents in use today. …
Matched Mixtures name: … MUCO-AID LIQUID ... CLIP Liquid Sanitizer ... SANIDINA® JABON LIQUIDO
Matched Salts name: … Chlorhexidine acetate
Matched Categories: … Irrigating Solutions ... Alimentary Tract and Metabolism ... Antiseptics and Disinfectants ... Biguanides and Amidines ... Antiinfectives and Antiseptics for Local Oral Treatment …
Matched Products: … 3M AVAGARD 9232 ANTISEPTIC HAND AND BODY WASH CLORHEXIDINE GLUCONATE 2% W/W SOLUTION BOTTE . ... Foster and Thrive ... Maxiclens Chlorhexidine gluconate Liquid Solution, 4% …
Vudalimab is under investigation in clinical trial NCT05005728 (Xmab®20717 (Vudalimab) Alone or in Combination With Chemotherapy or Targeted Therapy in Patients With Metastatic Castration-resistant Prostate Cancer).
Investigational
Matched Synonyms: … kappa/scfv-h-ch2-ch3, anti-(homo sapiens ctla4 (cytotoxic t-lymphocyte-associated protein 4, cd152)) and
A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic...
Approved
Nutraceutical
Matched Synonyms: … acide ascorbique ... Ascorbic acid ... Acidum ascorbicum …
Matched Name: … Ascorbic acid
Matched Description: … Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and ... It is found naturally in citrus fruits and many vegetables. ... A six carbon compound related to glucose. …
Matched Mixtures name: … Luna Vitamin and Mineral Bar for Women ... L-Methyl PNV DHA ... Evc Liquid Vitamins A,c,b6 With Beta Caro&zn …
Matched Categories: … ascorbic acid (vit C) and calcium ... Alimentary Tract and Metabolism ... Diet, Food, and Nutrition ... Genito Urinary System and Sex Hormones ... Vitamin C and analogues …
Matched Products: … Sodium Ascorbate and Ascorbic Acid Pwr ... Vit.c With N-M.bioflav.rose Hips and Rutin ... Timed Release and Esterified Vitamin C-1000 …
Ketotifen is a benzocycloheptathiophene derivative with potent antihistaminic and mast cell stabilizing properties. It has a similar structure to some other first-generation antihistamines such as cyproheptadine and azatadine. Ketotifen was first developed in Switzerland in 1970 by Sandoz Pharmaceuticals and was initially marketed for the treatment of anaphylaxis. In the...
Approved
Matched Description: … Ketotifen is a benzocycloheptathiophene derivative[A231204] with potent antihistaminic and mast cell ... allergic symptoms and disorders,[A231204] including urticaria, mastocytosis, and food allergy. ... It has a similar structure to some other first-generation antihistamines such as [cyproheptadine] and
Matched Categories: … Decongestants and Antiallergics ... Sulfur Compounds …
Matched Products: … Up and Up Eye Itch Relief ... Leader Allergy Eye ... Leader Eye Itch Relief Drops …
Investigational
Matched Synonyms: … (L120>A,L121>E,G123>A,A216>S,P217>S)-TACI (TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR, TUMOR NECROSIS …
Matched Categories: … Amino Acids, Peptides, and Proteins …
A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV).
Approved
Investigational
Matched Description: … A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon ... It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV). …
Matched Mixtures name: … Lamivudine and Zidovudine ... Lamivudine and Zidovudine ... Lamivudine and Zidovudine …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Nucleic Acid Synthesis Inhibitors ... lamivudine and abacavir ... lamivudine and dolutegravir ... zidovudine and lamivudine …
Matched Products: … Lamivudine and Zidovudine ... LUTIC SOLUCION ... EPIVIR SOLUCION ORAL …
Cefepime is a fourth-generation cephalosporin antibiotic developed in 1994. Cefepime is active against Gram-positive and Gram-negative bacteria, and has greater activity against both compared to third-generation antibiotics.[A2457,A249050] Cefepime is normally used to treat severe nosocomial pneumonia and infections caused by multi-resistant microorganisms such as Pseudomonas aeruginosa, and is also indicated...
Approved
Investigational
Matched Synonyms: … -7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(1-methylpyrrolidinium-1-yl)methyl
Matched Iupac: … thiazol-4-yl)-2-(methoxyimino)acetamido]-2-carboxylato-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl
Matched Description: … Cefepime is active against Gram-positive and Gram-negative bacteria, and has greater activity against ... [A2457,A249050] Cefepime is normally used to treat severe nosocomial pneumonia and infections caused ... by multi-resistant microorganisms such as _Pseudomonas aeruginosa_, and is also indicated for the empirical …
Matched Categories: … cefepime and amikacin ... Sulfur Compounds …
Matched Products: … Cefepime Hydrochloride and Dextrose ... Cefevon powder for solution for injection 2g/vial ... ROXIPIME POWDER FOR SOLUTION FOR INJECTION 2G/VIAL …
Displaying drugs 326 - 350 of 5157 in total