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Displaying drugs 351 - 375 of 1644 in total
Investigational
Matched Synonyms: … ELX 02
CA-074 methyl ester (CA-074Me) is a cell-permeable cathepsin B inhibitor. It is converted by cellular esterases to CA-074.[A258234,A258239]
Experimental
Matched Synonyms: … CA 074 Me ester ... CA 074 methyl ester …
Matched Name: … CA-074 methyl ester …
Matched Description: … CA-074 methyl ester (CA-074Me) is a cell-permeable cathepsin B inhibitor. ... It is converted by cellular esterases to CA-074.[A258234,A258239] …
Naloxone is an opioid antagonist medication used to block or reverse the effects of opioid drugs, particularly within the setting of drug overdoses which are rapidly becoming a leading cause of death worldwide. More specifically, naloxone has a high affinity for μ-opioid receptors, where it acts as an inverse agonist,...
Approved
Vet approved
Matched Iupac: … (1S,5R,13R,17S)-10,17-dihydroxy-4-(prop-2-en-1-yl)-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{ …
Matched Salts cas: … 357-08-4 …
Matched Mixtures name: … BUPREN 2MG/0.5MG SUBLINGUAL TABLET ... SUBOXONE SUBLINGUAL FILM 2MG/0.5 MG ... Suboxone 2 mg/0.5 mg sublingual tablets …
Matched Products: … Narcan Injection 0.02mg/ml ... Narcan Injection 0.4mg/ml ... MAPIN 0.4MG/ML INJECTION (1ML AMP) …
Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis.[A188529,A188532] Budesonide was granted FDA approval on 14 February 1994. It is also available in a combination product...
Approved
Matched Iupac: … {4,8}.0^{13,18}]icosa-14,17-dien-16-one ... 11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-6-propyl-5,7-dioxapentacyclo[10.8.0.0^{2,9}.0^ …
Matched Products: … BETACTIN LOCION 0.025% ... Pulmicort Respules 0.25mg/ml ... Pulmicort Nebuamp 0.125 mg/ml …
Clobetasone is a corticosteroid that is often employed topically as a treatment for a variety of conditions such as eczema, psoriasis, various forms of dermatitis, and also for certain ophthalmologic conditions. Topical clobetasone butyrate has shown minimal suppression of the Hypothalamic-pituitary-adrenal axis.
Approved
Matched Iupac: … ,11S,13S,14R,15S)-14-(2-chloroacetyl)-1-fluoro-14-hydroxy-2,13,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^ …
Matched Salts cas: … 25122-57-0
Matched Products: … Eumovate Crm 0.05% ... Eumovate Ont 0.05% ... AMISOL CREAM 0.05% w/w …
Pergolide is a long-acting dopamine agonist approved in 1982 for the treatment of Parkinson’s Disease. It is an ergot derivative that acts on the dopamine D2 and D3, alpha2- and alpha1-adrenergic, and 5-hydroxytryptamine (5-HT) receptors. It was indicated as adjunct therapy with levodopa/carbidopa in the symptomatic treatment of parkinsonian syndrome....
Approved
Investigational
Vet approved
Withdrawn
Matched Iupac: … (2R,4R,7R)-4-[(methylsulfanyl)methyl]-6-propyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca- …
Matched Products: … Permax Tab 0.05mg ... PERGOLID-NEURAX 0.25 MG ... PERGOLID-NEURAX 0.05 MG …
Investigational
Matched Synonyms: … BLD-0409
Investigational
Matched Synonyms: … STK-001
Human alpha-1 proteinase inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and zinc chloride fractionation.
Approved
Matched Synonyms: … 122320-05-2 …
Caprylic acid is an eight-carbon chain fatty acid, also known systematically as octanoic acid. It is found naturally in coconuts and breast milk. It is an oily liquid with a slightly unpleasant rancid-like smell that is minimally soluble in water.
Investigational
Matched Synonyms: … C8:0
Gadoteric acid, commonly used in the salt form gadoterate meglumine, is a macrocyclic, ionic gadolinium-based contrast agent (GBCA). It is composed of the organic acid DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) used for its chelating properties, and gadolinium (Gd3+). Gadoterate meglumine has one of the highest thermodynamic stability, apparent stability, and kinetic stability,...
Approved
Matched Products: … Artirem 0,0025mmol/ml - Injektionslösung ... DOTAGRAF SOLUTION FOR INJECTION 0.5 MMOL/ML ... CLARISCAN SOLUTION FOR INJECTION IN VIAL 0.5 MMOL/ML …
Investigational
Matched Synonyms: … Mb-003 component c13c6-fr1 …
Omidenepag isopropyl is a topical ocular hypotensive agent used to reduce intraocular pressure (IOP) in patients with glaucoma and ocular hypertension. Omidenepag isopropyl is quickly metabolized to its active metabolite, omidenepag, a molecule with high selectivity and agonistic activity towards the prostaglandin E2 (EP2) receptor.[A253263,A253268] Prostanoid FP receptor agonists (FP...
Approved
Investigational
Matched Products: … Eybelis ophthalmic solution 0.002% ... EYBELIS OPHTHALMIC SOLUTION 0.002% …
Fludrocortisone is a synthetic mineralocorticoid used in conjunction with hydrocortisone to replace missing endogenous corticosteroids in patients with adrenal insufficiency.[A187169,A187187] It is functionally similar to aldosterone, the body's primary endogenous mineralocorticoid, and is structurally analogous to cortisol, differing only by a fluorine atom at the 9-position of the steroid structure...
Approved
Investigational
Matched Products: … Florinef Acetate 0.1mg ... ASTONIN-H 0,1 MG TABLET, 100 ADET ... FLORINEF TABLET 0.1 mg …
Sar9, Met (O2)11-Substance P is a neurokinin-1 receptor agonist. It is an analog of the naturally occurring human neuropeptide Substance P, which can be found throughout the body, including in the airways of humans and many other species.
Investigational
Matched Synonyms: … Bolton hunter-9-sar-11-met(02)-substance P …
Chondroitin sulfate is a glycosaminoglycan considered as a symptomatic slow-acting drug for osteoarthritis (SYSADOA). The SYSADOA status suggested a pain relief and increased joint mobility after a relative long regular administration, as well as a long-lasting effect after the end of the treatment. Chondroitin sulfate is composed of alternating 1,3-N-acetyl-β-d-galactosamine...
Approved
Investigational
Nutraceutical
Matched Salts cas: … 39455-18-0
Matched Products: … HIRUDOID FORT %0,445 JEL, 40 G ... HIRUDOID FORT %0,445 KREM, 40 G …
Flumethasone is a moderately potent difluorinated corticosteroid ester with anti-inflammatory, antipruritic and vasoconstrictive properties. As it is a privalate salt, its anti-inflammatory action is concentrated at the site of application. This local effect on diseased areas results in a prompt decrease in inflammation, exudation and itching.
Approved
Vet approved
Matched Iupac: … 14R,15S,17S)-1,8-difluoro-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵ …
Matched Mixtures name: … LOCASALENE 0,2MG/G+30MG/G MERHEM, 30 G ... LOCACORTENE VİOFORME 0,2 MG/G+30 MG/G KREM, 15 G ... LOCACORTENE VİOFORME 0,2 MG/G+30 MG/G KREM, 30 G …
Matched Products: … Locacorten .03% ... CERSON 0.2 MG/G CREME ... CERSON 0.2 MG/G FETTCREME …
Investigational
Matched Synonyms: … Ads-001 free acid ... Double stranded oligomer ADS-001 RNA interference-based liver targeted therapeutic …
Multiple sclerosis, or MS, is a devastating inflammatory disease that often progresses and causes severe neurological, physical, and cognitive effects. Fingolimod is a sphingosine 1-phosphate receptor modulator for the treatment of relapsing-remitting multiple sclerosis. It was developed by Novartis and initially approved by the FDA in 2010. Fingolimod was also...
Approved
Investigational
Matched Salts cas: … 162359-56-0
Matched Products: … Gilenya Capsule 0.5mg ... Gilenya 0.5mg Hard Capsule ... GILENYA CAPSULE 0.25mg
A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike physostigmine, does not cross the blood-brain barrier.
Approved
Vet approved
Matched Products: … NEOSTIGMINA 0. 5 MG / MLSOLUCION INYECTABLE ... Prostigmin Ampoules 0.5mg/ml ... Neostigmine Methylsulfate Inj 0.5mg/ml USP …
Vidutolimod is a Toll-like receptor 9 (TLR9) agonist. It is an investigational cancer vaccine.
Investigational
Matched Synonyms: … Cmp-001 component cpg-a oligodeoxynucleotide tlr9 agonist …
Epinastine is used for the prevention of itching associated with allergic conjunctivitis. It has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding to both the H1- and H2-receptors to...
Approved
Investigational
Matched Iupac: … 2,4-diazatetracyclo[12.4.0.0^{2,6}.0^{7,12}]octadeca-1(18),3,7,9,11,14,16-heptaen-3-amine …
Matched Salts cas: … 108929-04-0
Matched Products: … Relestat 0,5 mg/ml Augentropfen ... FLURINOL ® JARABE 0.2 G / 100 ML ... RELESTAT % 0,05 GÖZ DAMLASI, ÇÖZELTİ, 5 ML …
Investigational
Matched Synonyms: … OSSM-001
Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist used for the treatment of severe pain.[A186283,A186292] It is also commonly used as an alternative to methadone for the treatment of severe opioid addiction. Buprenorphine is commercially available as the brand name product Suboxone which is...
Approved
Illicit
Investigational
Vet approved
Matched Iupac: … {1,6}.0^{6,14}.0^{7,12}]icosa-7,9,11-trien-11-ol ... cyclopropylmethyl)-16-[(2S)-2-hydroxy-3,3-dimethylbutan-2-yl]-15-methoxy-13-oxa-3-azahexacyclo[13.2.2.1^{2,8}.0^ …
Matched Mixtures name: … BUPREN 2MG/0.5MG SUBLINGUAL TABLET ... SUBOXONE SUBLINGUAL FILM 2MG/0.5 MG ... Suboxone 2 mg/0.5 mg sublingual tablets …
Matched Products: … TEMGESIC INJECTION 0.3 mg/ml ... TEMGESIC INJECTION 0.3MG/ML (1ML) ... Temgesic 0,2 mg Sublingualtabletten …
Investigational
Matched Synonyms: … (92.6%)-(IGHD)-IGHJ4*01 (92.9%), CDR-IMGT (8.7.5) (26-33.51-57.96 ... FIBRILS), CHIMERIC MONOCLONAL ANTIBODY (GAMMA1 HEAVY CHAIN CHIMERIC (1-441) (MUS MUSCULUS VH (IGHV2-3*01
Displaying drugs 351 - 375 of 1644 in total