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Displaying drugs 351 - 375 of 10558 in total

Ponesimod

Ponesimod is a selective sphingosine 1-phosphate receptor 1 modulator indicated in the treatment of relapsing forms of multiple sclerosis in adults.[A232079,L32709] Ponesimod was developed out of a need for a more selective modulator of sphingosine 1-phosphate receptor 1 than fingolimod. Fingolimod's activity at sphingosine 1-phosphate receptor 3 was suspected to...
Approved
Investigational
Matched Description: … Ponesimod is a selective sphingosine 1-phosphate receptor 1 modulator indicated in the treatment of relapsing ... phosphate receptor 1 than [fingolimod]. ... A232079,L32709] Ponesimod was developed out of a need for a more selective modulator of sphingosine 1- …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Sphingosine 1-phosphate Receptor Modulator ... Sphingosine 1 Phosphate Receptor Modulators ... Sphingosine-1-phosphate (S1P) receptor modulators …

Brentuximab vedotin

Brentuximab vedotin, also known as Adcetris®, is an antibody-drug conjugate that combines an anti-CD30 antibody with the drug monomethyl auristatin E (MMAE). It is an anti-neoplastic agent used in the treatment of Hodgkin's lymphoma and systemic anaplastic large-cell lymphoma. Brentuximab vedotin was initially approved in 2011. In January 2012, the...
Approved
Investigational
Matched Description: … [L1737] The ECHELON-1 study results demonstrated superior efficacy of the drug combined with a chemotherapy …
Matched Products: … ADCETRIS 50 MG IV INFÜZYONLUK ÇÖZELTI KONSANTRESI IÇIN TOZ IÇEREN FLAKON ,FLAKON, 1 ADET …

Carbamoylcholine

Carbamoylcholine, also known as carbachol, is a muscarinic agonist discovered in 1932. Carbamoylcholine was initially used as a treatment for migraines, induction of diuresis, and other parasympathetic effects. Carbamoylcholine was granted FDA approval on 28 September 1972.
Approved
Matched Products: … MIOSTAT %0.01 İNTRAOKÜLER ÇÖZELTİ (1 ADET) …

Rolapitant

Rolapitant is a potent, highly selective, long-acting Neurokinin-1 (NK-1) receptor antagonist approved for the prevention of delayed chemotherapy-induced nausea and vomiting (CINV) in adults. Delayed-phase CINV typically occurs >24 hours after chemotherapy treatment and is principally mediated by Neurokinin-1 and its ligand Substance P, which is released in the gut...
Approved
Investigational
Matched Iupac: … (5S,8S)-8-{[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl}-8-phenyl-1,7-diazaspiro[4.5]decan-2 …
Matched Description: … Neurokinin-1 is also known as Tachykinin Receptor 1 (TACR1), Neurokinin 1 Receptor (NK1R), and Substance ... Rolapitant is a potent, highly selective, long-acting Neurokinin-1 (NK-1) receptor antagonist approved ... CINV typically occurs >24 hours after chemotherapy treatment and is principally mediated by Neurokinin-1 …
Matched Salts cas: … 858102-79-1 …
Matched Categories: … Neurokinin 1 Antagonists ... Neurokinin-1 Receptor Antagonists ... Substance P/Neurokinin-1 Receptor Antagonist …

Urea

A compound formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.
Approved
Investigational
Matched Mixtures name: … CANESTEN ULTRA UÑAS 1% ... ROZA %1 + %2 KREM (30 G) ... HYDROCORTISONE 1% ET UREA 5% CREAM …
Matched Products: … PYTEST 14C ÜRE NEFES TESTİ İÇİN KAPSÜL, 1 ADET …

Fludarabine

Fludarabine is a chemotherapeutic agent used in the treatment of hematological malignancies. It is commonly marketed under the brand name Fludara.
Approved
Matched Products: … FLUDALYM 50 MG/2 ML IV ENJEKSİYON/İNFÜZYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON, 1 ADET ... DARABIN 50 MG IV ENJEKSIYON/INFÜZYON ICIN LIYOFILIZE TOZ IÇEREN FLAKON ,FLAKON, 1 ADET …

Valaciclovir

Valaciclovir (valacyclovir), also known as Valtrex, is an antiviral drug that has been used to manage and treat various herpes infections for more than 2 decades. It was initially approved by the FDA in 1995 [FDA label] and marketed by GlaxoSmithKline . Valacyclovir is the L-valine ester of aciclovir. It...
Approved
Investigational
Matched Products: … VALACICLOVIR 1 G …

Nandrolone decanoate

Nandrolone decanoate, also known as nandrolone caprinate, is an alkylated anabolic steroid indicated in the management of anemia of renal insufficiency and as an adjunct therapy in the treatment of senile and postmenopausal osteoporosis.[A233789,A233849,L32564,L9464] The process for creating esters of nandrolone was patented in Spain in 1959 and in 1960,...
Approved
Illicit
Matched Iupac: … 11aS)-11a-methyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1- …
Matched Products: … PARABOLIN RETARD 25 MG AMPUL, 1 ADET …

Yellow fever vaccine

Yellow fever vaccine prevents against Yellow Fever, a viral hemorrhagic disease caused by the transmission of a flavivirus through the bite of an infected mosquito. Symptoms of Yellow fever can range from asymptomatic, to mild flu-like illness, to more severe symptoms such as shock, jaundice, internal bleeding, and organ failure...
Approved
Investigational
Matched Products: … 0,5 ML IM/SC ENJEKSİYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON VE ÇÖZÜCÜ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 …

Everolimus

Everolimus is a derivative of Rapamycin (sirolimus), and works similarly to Rapamycin as an mTOR (mammalian target of rapamycin) inhibitor. It is currently used as an immunosuppressant to prevent rejection of organ transplants. In a similar fashion to other mTOR inhibitors Everolimus' effect is solely on the mTORC1 protein and...
Approved
Matched Iupac: … (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-( …
Matched Products: … Aderolio 1 mg – Tabletten ... CERTICAN TABLETS 1 MG ... Certican 1 mg - Tabletten …

Cetirizine

Cetirizine, also commonly known as Zyrtec, is an orally active second-generation histamine H1 antagonist proven effective in the treatment of various allergic symptoms, such as sneezing, coughing, nasal congestion, hives, and other symptoms , . One of the most common uses for this drug is for a condition called allergic...
Approved
Matched Iupac: … 2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid …
Matched Salts cas: … 83881-52-1 …
Matched Products: … CETIRIZINA 1% GOTAS ... CETIRIZINA GOTAS 1% ... CETIRIZINA 1 MG./ML. …

Povidone-iodine

Povidone-iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It contains from 9.0% to 12.0% available iodine, calculated on a dry basis. This unique complex was discovered in 1955 at the Industrial Toxicology Laboratories in Philadelphia by H. A. Shelanski and M. V. Shelanski. During in...
Approved
Matched Mixtures name: … Mlp A-1 ... Pro-C-Dure 1 Kit …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Douche Tray 1% ... Certus PVP-1 Prep Swabstick ... Solunet 1 Brosse 0.75% …

Dexpanthenol

Dexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Dexpanthenol is enzymatically cleaved to form pantothenic acid, which is an essential component of Coenzyme A, which acts as a cofactor in many enzymatic reactions that...
Approved
Matched Mixtures name: … NASOWELL 1 MG/ML+ 50 MG/ML BURUN SPREYİ, ÇÖZELTİ, 1 ADET ... Otrivin plus Dexpanthenol 1 mg/ml + 50 mg/ml Nasenspray, Lösung …
Matched Products: … Corneregel 50 mg Dexpanthenol pro 1 g Augengel …

Hexylresorcinol

Hexylresorcinol is a substituted dihydroxybenzene. It exhibits antiseptic, anthelmintic, and local anesthetic properties. It can be found in topical applications for minor skin infections and in oral solutions or throat lozenges for pain relief and first aid antiseptic. The compound may also be used commonly in various commercial cosmetic anti-aging...
Approved

Dorzolamide

Dorzolamide is a non-bacteriostatic sulfonamide derivative and topical carbonic anhydrase (CA) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and ocular hypertension. It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes. Unlike oral CA inhibitors, dorzolamide...
Approved
Matched Mixtures name: … DORZASOPT GÖZ DAMLASI ,1 ŞIŞE ... XOLATIM %2+ %0,5 GÖZ DAMLASI, ÇÖZELTİ ,5 ML,1 ŞİŞE …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … DORZAMED %2 GÖZ DAMLASI ,1 ŞIŞE ... XOLADOR %2 GÖZ DAMLASI ,5 ML, 1 ŞIŞE …

Maraviroc

Maraviroc (brand-named Selzentry, or Celsentri outside the U.S.) is a chemokine receptor antagonist drug developed by the drug company Pfizer that is designed to act against HIV by interfering with the interaction between HIV and CCR5. It was originally labelled as UK-427857 during development but was assigned the Maraviroc name...
Approved
Investigational
Matched Iupac: … phenylpropyl]cyclohexane-1-carboxamide ... 1S)-3-[(1R,3S,5S)-3-[3-methyl-5-(propan-2-yl)-4H-1,2,4-triazol-4-yl]-8-azabicyclo[3.2.1]octan-8-yl]-1- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Salicylamide

Salicylamide is the common name for the substance o-hydroxybenzamide, or amide of salicyl. Salicylamide is a non-prescription drug with analgesic and antipyretic properties. It has similar medicinal uses to aspirin. Salicylamide is used in combination with both aspirin and caffeine in the over-the-counter pain remedies
Approved

Insulin human

Human Insulin, also known as Regular Insulin, is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Human insulin is produced by recombinant DNA technology and is identical to endogenously produced insulin. Typically prescribed for the management of diabetes mellitus,...
Approved
Investigational
Matched Description: … Regular Insulin, is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 ... as a crystalline suspension of insulin with protamine and zinc, resulting in an onset of action in 1 ... Insulin is an important treatment in the management of Type 1 Diabetes (T1D) which is caused by an autoimmune …
Matched Mixtures name: … MIXTARD 30 HM 100 IU/ML ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 1 ADET ... MIXTARD 30 HM 100 IU/ML ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 1 ADET …
Matched Products: … HUMULIN R 100 IU/ML ÇÖZELTİ İÇEREN FLAKON, 1 ADET ... HUMULIN N (NPH) 100 IU/ML SÜSPANSİYON İÇEREN FLAKON, 1 ADET ... ACTRAPID HM 100 IU/ML ENJEKSİYONLUK ÇÖZELTI İÇEREN FLAKON, 1 ADET …

Lenacapavir

HIV/AIDS remains an area of concern despite the introduction of numerous successful therapies, mainly due to the emergence of multidrug resistance and patient difficulty in adhering to treatment regimens.[A244170, A244175] Lenacapavir is a first-in-class capsid inhibitor that demonstrates picomolar HIV-1 inhibition as a monotherapy in vitro, little to no cross-resistance...
Approved
Investigational
Matched Iupac: … N-[(1S)-1-{3-[4-chloro-3-methanesulfonamido-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl]-6-(3-methanesulfonyl ... -3-methylbut-1-yn-1-yl)pyridin-2-yl}-2-(3,5-difluorophenyl)ethyl]-2-[(2S,4R)-5,5-difluoro-9-(trifluoromethyl ... )-7,8-diazatricyclo[4.3.0.0^{2,4}]nona-1(6),8-dien-7-yl]acetamide …
Matched Description: … [A244170, A244175] Lenacapavir is a first-in-class capsid inhibitor that demonstrates picomolar HIV-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Human Immunodeficiency Virus 1 Capsid Inhibitor …

Benzethonium

Benzethonium is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties. Its salt form, benzethonium chloride, is primarily used as a skin disinfectant at concentrations of 0.1-0.2 %, which are safe and effective concentrations for the compound specified by the U.S. Food and Drug Administration (FDA)....
Approved
Matched Products: … 3 in 1 First Aid Wound Care ... Skin Cleanser & Deodorizer Liq .1% ... Charm Tex 3 IN 1 Antibacterial Shave Gel Body Wash …

Enfuvirtide

Enfuvirtide is a 36 amino acid biomimetic peptide that is structurally similar to the HIV proteins that are responsible for the fusion of the virus to cell membranes and subsequent intracellular uptake. The first agent in the novel class of antiretroviral drugs called HIV fusion inhibitors, enfuvirtide works by inhibiting...
Approved
Investigational
Matched Description: … novel class of antiretroviral drugs called HIV fusion inhibitors, enfuvirtide works by inhibiting HIV-1 …
Matched Categories: … Human Immunodeficiency Virus 1 Fusion Inhibitor …

Amiodarone

Amiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings. Most known for its approved indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and inpatient setting for atrial fibrillation. Because of its ability to cause serious toxicity and possibly death, amiodarone...
Approved
Investigational
Matched Iupac: … {2-[4-(2-butyl-1-benzofuran-3-carbonyl)-2,6-diiodophenoxy]ethyl}diethylamine …
Matched Products: … AMIODARONE FARMA 1 …

Zonisamide

Zonisamide is a sulfonamide anticonvulsant used as an adjunctive therapy in adults with partial-onset seizures.[L42530,L42535] Zonisamide may act by blocking repetitive firing of voltage-gated sodium channels, leading to a reduction of T-type calcium channel currents or by binding allosterically to GABA receptors. This latter action may inhibit the uptake of...
Approved
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Dihydrocodeine

Dihydrocodeine is an opioid analgesic used as an alternative or adjunct to codeine to treat moderate to severe pain, severe dyspnea, and cough. It is semi-synthetic, and was developed in Germany in 1908 during an international search to find a more effective antitussive agent to help reduce the spread of...
Approved
Illicit
Matched Salts cas: … 5965-15-1 …

Escitalopram

Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic citalopram. It is used to restore serotonergic function in the treatment of depression and anxiety.[L8513,L8516,L8522] Escitalopram is approximately 150 times more potent than citalopram’s R-enantiomer and is responsible for the vast majority of citalopram’s clinical activity, with...
Approved
Matched Iupac: … (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile …
Displaying drugs 351 - 375 of 10558 in total